Basic Information:

  VIRBase ID:  

HHID00012797

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-33b-3p:  MIMAT0004811          IYD:  NM_001318495     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-33b-3p	IYD
miRBase Accession/Entrez ID	MIMAT0004811	389434
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	C6orf71//DEHAL1//IYD-1//TDH4

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-33b-3p	rs1014636340 chr17:17813869    C/T rs1175344913 chr17:17813860    C/T rs1212055173 chr17:17813859    G/C rs1333766161 chr17:17813870    G/A rs1359466877 chr17:17813864    A/G rs751021350 chr17:17813857    G/A rs1272832890 chr17:17813873    G/A rs1296048342 chr17:17813872    G/A rs1399118390 chr17:17813874    C/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	IYD	chr6:150713259(+) A-I      intronic chr6:150718510(+) A-I      intronic chr6:150712284(+) A-I      intronic chr6:150718567(+) A-I      intronic chr6:150718599(+) A-I      intronic chr6:150712343(+) A-I      intronic chr6:150713283(+) A-I      intronic chr6:150713011(+) A-I      intronic chr6:150712187(+) A-I      intronic chr6:150712113(+) A-I      intronic chr6:150712098(+) A-I      intronic chr6:150718626(+) A-I      intronic chr6:150708455(+) A-I      intronic chr6:150713206(+) A-I      intronic chr6:150713290(+) A-I      intronic chr6:150718431(+) A-I      intronic chr6:150718509(+) A-I      intronic chr6:150712226(+) A-I      intronic chr6:150712242(+) A-I      intronic chr6:150712275(+) A-I      intronic chr6:150720060(+) A-I      3'UTR chr6:150720077(+) A-I      3'UTR chr6:150720078(+) A-I      3'UTR chr6:150720158(+) A-I      3'UTR chr6:150720159(+) A-I      3'UTR chr6:150720161(+) A-I      3'UTR chr6:150724115(+) A-I      3'UTR chr6:150724133(+) A-I      3'UTR chr6:150724138(+) A-I      3'UTR chr6:150724150(+) A-I      3'UTR chr6:150724163(+) A-I      3'UTR chr6:150724164(+) A-I      3'UTR chr6:150724168(+) A-I      3'UTR chr6:150724176(+) A-I      3'UTR chr6:150724189(+) A-I      3'UTR chr6:150720136(+) A-I      3'UTR chr6:150720144(+) A-I      3'UTR chr6:150720139(+) A-I      3'UTR chr6:150720083(+) A-I      3'UTR chr6:150720064(+) A-I      3'UTR chr6:150719922(+) A-I      3'UTR chr6:150719969(+) A-I      3'UTR chr6:150716093(+) A-I      intronic chr6:150712262(+) A-I      intronic chr6:150713222(+) A-I      intronic chr6:150713277(+) A-I      intronic chr6:150716091(+) A-I      intronic chr6:150724112(+) A-I      3'UTR chr6:150724143(+) A-I      3'UTR chr6:150720103(+) A-I      3'UTR chr6:150724103(+) A-I      3'UTR chr6:150720091(+) A-I      3'UTR chr6:150712119(+) A-I      intronic chr6:150718645(+) A-I      intronic chr6:150712164(+) A-I      intronic chr6:150718443(+) A-I      intronic chr6:150713294(+) A-I      intronic chr6:150710158(+) A-I      intronic

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-33b-3p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     -
	IYD	Exosome Blood     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	PMID
NoncoRNA	hsa-miR-33b-3p	Cisplatin 5702198       27559850

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-33b-3p
Interactor2: IYD

Evidence Support:

Weak-Evidence	RNA-Seq
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	31570108	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	ARPE-19 human RPE cells	Interactor2 expression	None
Description	Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).