Basic Information:

  VIRBase ID:  

HHID00012658

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-33b-3p:  MIMAT0004811          MYOCD:  NM_153604     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-33b-3p	MYOCD
miRBase Accession/Entrez ID	MIMAT0004811	93649
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	MGBL//MYCD

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-33b-3p	rs1014636340 chr17:17813869    C/T rs1175344913 chr17:17813860    C/T rs1212055173 chr17:17813859    G/C rs1333766161 chr17:17813870    G/A rs1359466877 chr17:17813864    A/G rs751021350 chr17:17813857    G/A rs1272832890 chr17:17813873    G/A rs1296048342 chr17:17813872    G/A rs1399118390 chr17:17813874    C/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	MYOCD	chr17:12596204(+) A-I      intronic chr17:12596202(+) A-I      intronic chr17:12596192(+) A-I      intronic chr17:12596180(+) A-I      intronic chr17:12596179(+) A-I      intronic chr17:12596177(+) A-I      intronic chr17:12658843(+) A-I      intronic chr17:12658840(+) A-I      intronic chr17:12658848(+) A-I      intronic chr17:12596176(+) A-I      intronic chr17:12596199(+) A-I      intronic chr17:12596173(+) A-I      intronic chr17:12596225(+) A-I      intronic chr17:12596191(+) A-I      intronic chr17:12596209(+) A-I      intronic chr17:12596208(+) A-I      intronic chr17:12661050(+) A-I      intronic chr17:12644149(+) A-I      intronic chr17:12644086(+) A-I      intronic chr17:12643333(+) A-I      intronic chr17:12643322(+) A-I      intronic chr17:12643306(+) A-I      intronic chr17:12633069(+) A-I      intronic chr17:12633046(+) A-I      intronic chr17:12599438(+) A-I      intronic chr17:12582158(+) A-I      intronic chr17:12644192(+) A-I      intronic chr17:12647007(+) A-I      intronic chr17:12659018(+) A-I      intronic chr17:12659027(+) A-I      intronic chr17:12644185(+) A-I      intronic chr17:12661045(+) A-I      intronic chr17:12665080(+) A-I      intronic chr17:12633501(+) A-I      intronic chr17:12659948(+) A-I      intronic chr17:12658916(+) A-I      intronic chr17:12658867(+) A-I      intronic chr17:12658842(+) A-I      intronic chr17:12636539(+) A-I      intronic chr17:12647024(+) A-I      intronic chr17:12620307(+) A-I      intronic chr17:12643392(+) A-I      intronic chr17:12658807(+) A-I      intronic chr17:12643459(+) A-I      intronic chr17:12651359(+) A-I      intronic chr17:12644971(+) A-I      intronic chr17:12659958(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	MYOCD	chr17:12655744-12655745(+) m6A CDS//exon       24981863 chr17:12655800-12655801(+) m6A CDS//exon       24981863 chr17:12655821-12655822(+) m6A CDS//exon       24981863 chr17:12655845-12655846(+) m6A CDS//exon       24981863 chr17:12656022-12656023(+) m6A CDS//exon       24981863 chr17:12656145-12656146(+) m6A CDS//exon       25456834//24981863 chr17:12656157-12656158(+) m6A CDS//exon       25456834//24981863 chr17:12656194-12656195(+) m6A CDS//exon       25456834//24981863 chr17:12656206-12656207(+) m6A CDS//exon       25456834//24981863 chr17:12656371-12656372(+) m6A CDS//exon       24981863 chr17:12656465-12656466(+) m6A CDS//exon       24981863 chr17:12666689-12666690(+) m6A CDS       24981863 chr17:12666739-12666740(+) m6A CDS       24981863 chr17:12666764-12666765(+) m6A CDS       24981863 chr17:12666808-12666809(+) m6A CDS       25456834//24981863 chr17:12666824-12666825(+) m6A CDS       25456834//24981863 chr17:12666938-12666939(+) m6A CDS       24981863 chr17:12666989-12666990(+) m6A 3'UTR       24981863 chr17:12667045-12667046(+) m6A 3'UTR       24981863 chr17:12667097-12667098(+) m6A 3'UTR       24981863 chr17:12667103-12667104(+) m6A 3'UTR       24981863 chr17:12667243-12667244(+) m6A 3'UTR       24981863 chr17:12667489-12667490(+) m6A 3'UTR       24981863 chr17:12667497-12667498(+) m6A 3'UTR       24981863 chr17:12667502-12667503(+) m6A 3'UTR       24981863 chr17:12667554-12667555(+) m6A 3'UTR       24981863 chr17:12667578-12667579(+) m6A 3'UTR       24981863 chr17:12667591-12667592(+) m6A 3'UTR       24981863 chr17:12667624-12667625(+) m6A 3'UTR       24981863 chr17:12667638-12667639(+) m6A 3'UTR       24981863 chr17:12667650-12667651(+) m6A 3'UTR       24981863 chr17:12667725-12667726(+) m6A 3'UTR       24981863 chr17:12667741-12667742(+) m6A 3'UTR       24981863 chr17:12667802-12667803(+) m6A 3'UTR       24981863 chr17:12667873-12667874(+) m6A 3'UTR       24981863 chr17:12667878-12667879(+) m6A 3'UTR       24981863 chr17:12667915-12667916(+) m6A 3'UTR       24981863 chr17:12667938-12667939(+) m6A 3'UTR       24981863 chr17:12668087-12668088(+) m6A 3'UTR       24981863 chr17:12668166-12668167(+) m6A 3'UTR       24981863 chr17:12668228-12668229(+) m6A 3'UTR       24981863 chr17:12668338-12668339(+) m6A 3'UTR       24981863 chr17:12668394-12668395(+) m6A 3'UTR       24981863 chr17:12668430-12668431(+) m6A 3'UTR       24981863 chr17:12668504-12668505(+) m6A 3'UTR       24981863 chr17:12669021-12669022(+) m6A 3'UTR       24981863 chr17:12669092-12669093(+) m6A 3'UTR       24981863 chr17:12669129-12669130(+) m6A 3'UTR       24981863 chr17:12669134-12669135(+) m6A 3'UTR       24981863 chr17:12669196-12669197(+) m6A 3'UTR       24981863 chr17:12669660-12669661(+) m6A 3'UTR       24981863 chr17:12669684-12669685(+) m6A 3'UTR       24981863 chr17:12670418-12670419(+) m6A 3'UTR       24981863 chr17:12670434-12670435(+) m6A 3'UTR       24981863 chr17:12671087-12671088(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-33b-3p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     -
	MYOCD	Exosome Blood     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	PMID
NoncoRNA	hsa-miR-33b-3p	Cisplatin 5702198       27559850

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-33b-3p
Interactor2: MYOCD

Evidence Support:

Weak-Evidence	RNA-Seq
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	31570108	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	ARPE-19 human RPE cells	Interactor2 expression	None
Description	Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).