Basic Information:

  VIRBase ID:  

HHID00012593

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5908

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-33b-3p:  MIMAT0004811          CSRNP3:  NM_001172173     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-33b-3p	CSRNP3
miRBase Accession/Entrez ID	MIMAT0004811	80034
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	FAM130A2//PPP1R73//TAIP-2//TAIP2

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-33b-3p	rs1014636340 chr17:17813869    C/T rs1175344913 chr17:17813860    C/T rs1212055173 chr17:17813859    G/C rs1333766161 chr17:17813870    G/A rs1359466877 chr17:17813864    A/G rs751021350 chr17:17813857    G/A rs1272832890 chr17:17813873    G/A rs1296048342 chr17:17813872    G/A rs1399118390 chr17:17813874    C/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	CSRNP3	chr2:166455585(+) A-I      intronic chr2:166455584(+) A-I      intronic chr2:166456039(+) A-I      intronic chr2:166456075(+) A-I      intronic chr2:166455596(+) A-I      intronic chr2:166455478(+) A-I      intronic chr2:166455966(+) A-I      intronic chr2:166455984(+) A-I      intronic chr2:166465788(+) A-I      intronic chr2:166501764(+) A-I      intronic chr2:166501765(+) A-I      intronic chr2:166382179(+) A-I      intronic chr2:166382176(+) A-I      intronic chr2:166378655(+) A-I      intronic chr2:166510210(+) A-I      intronic chr2:166472319(+) A-I      intronic chr2:166456023(+) A-I      intronic chr2:166508458(+) A-I      intronic chr2:166455495(+) A-I      intronic chr2:166511402(+) A-I      intronic chr2:166456037(+) A-I      intronic chr2:166456069(+) A-I      intronic chr2:166333873(+) A-I      intronic chr2:166340783(+) A-I      intronic chr2:166455753(+) A-I      intronic chr2:166508266(+) A-I      intronic chr2:166508349(+) A-I      intronic chr2:166472515(+) A-I      intronic chr2:166340786(+) A-I      intronic chr2:166455581(+) A-I      intronic chr2:166482443(+) A-I      intronic chr2:166455500(+) A-I      intronic chr2:166340768(+) A-I      intronic chr2:166529922(+) A-I      intronic chr2:166455580(+) A-I      intronic chr2:166378723(+) A-I      intronic chr2:166455606(+) A-I      intronic chr2:166455609(+) A-I      intronic chr2:166471851(+) A-I      intronic chr2:166508346(+) A-I      intronic chr2:166510224(+) A-I      intronic chr2:166522166(+) A-I      intronic chr2:166502312(+) A-I      intronic chr2:166510428(+) A-I      intronic chr2:166488964(+) A-I      intronic chr2:166510208(+) A-I      intronic chr2:166509130(+) A-I      intronic chr2:166456077(+) A-I      intronic chr2:166456091(+) A-I      intronic chr2:166456040(+) A-I      intronic chr2:166455723(+) A-I      intronic chr2:166455521(+) A-I      intronic chr2:166340769(+) A-I      intronic chr2:166378630(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	CSRNP3	chr2:166533044-166533045(+) m6A CDS       22608085 chr2:166533080-166533081(+) m6A CDS       22608085 chr2:166535300-166535301(+) m6A CDS       24209618//24981863//22608085 chr2:166535326-166535327(+) m6A CDS       24209618//24981863//22608085 chr2:166535332-166535333(+) m6A CDS       24981863//22608085 chr2:166535343-166535344(+) m6A CDS       24981863//22608085 chr2:166535448-166535449(+) m6A CDS       24981863//22608085 chr2:166535465-166535466(+) m6A CDS       24981863//22608085 chr2:166535840-166535841(+) m6A CDS       24981863//22575960//22608085 chr2:166535862-166535863(+) m6A CDS       24981863//22575960//22608085 chr2:166535877-166535878(+) m6A CDS       24981863//22575960//22608085 chr2:166536067-166536068(+) m6A CDS       22608085 chr2:166536248-166536249(+) m6A CDS       22608085 chr2:166536282-166536283(+) m6A 3'UTR       22608085 chr2:166536346-166536347(+) m6A 3'UTR       22608085 chr2:166536353-166536354(+) m6A 3'UTR       22608085 chr2:166536362-166536363(+) m6A 3'UTR       22608085 chr2:166536387-166536388(+) m6A 3'UTR       22608085 chr2:166536471-166536472(+) m6A 3'UTR       22608085 chr2:166536532-166536533(+) m6A 3'UTR       22608085 chr2:166536542-166536543(+) m6A 3'UTR       22608085 chr2:166537174-166537175(+) m6A 3'UTR       22608085 chr2:166537181-166537182(+) m6A 3'UTR       22608085 chr2:166537318-166537319(+) m6A 3'UTR       22608085 chr2:166537352-166537353(+) m6A 3'UTR       22608085 chr2:166537363-166537364(+) m6A 3'UTR       22608085 chr2:166537530-166537531(+) m6A 3'UTR       22608085 chr2:166537542-166537543(+) m6A 3'UTR       22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-33b-3p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     -
	CSRNP3	Exosome Blood     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	PMID
NoncoRNA	hsa-miR-33b-3p	Cisplatin 5702198       27559850

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-33b-3p
Interactor2: CSRNP3

Evidence Support:

Weak-Evidence	RNA-Seq
Prediction-Evidence	DIANA-microT//miRDB
Support Database	ViRBase

References:

PMID	31570108	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	ARPE-19 human RPE cells	Interactor2 expression	None
Description	Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).