Detail Information

Basic Information:


  VIRBase ID:  

HHID00012410

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-33b-3p:           ZFYVE26:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-33b-3p ZFYVE26
miRBase
Accession/Entrez ID		 MIMAT0004811 23503
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - FYVE-CENT//SPG15

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-33b-3p
rs1014636340 chr17:17813869    C/T
rs1175344913 chr17:17813860    C/T
rs1212055173 chr17:17813859    G/C
rs1333766161 chr17:17813870    G/A
rs1359466877 chr17:17813864    A/G
rs751021350 chr17:17813857    G/A
rs1272832890 chr17:17813873    G/A
rs1296048342 chr17:17813872    G/A
rs1399118390 chr17:17813874    C/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR ZFYVE26
chr14:68225522(-) A-I      intronic
chr14:68199390(-) A-I      intronic
chr14:68227411(-) A-I      intronic
chr14:68209771(-) A-I      intronic
chr14:68199431(-) A-I      intronic
chr14:68227414(-) A-I      intronic
chr14:68209725(-) A-I      intronic
chr14:68199383(-) A-I      intronic
chr14:68225521(-) A-I      intronic
chr14:68209753(-) A-I      intronic
chr14:68199399(-) A-I      intronic
chr14:68203847(-) A-I      intronic
chr14:68225789(-) A-I      intronic
chr14:68224635(-) A-I      intronic
chr14:68199554(-) A-I      intronic
chr14:68209961(-) A-I      intronic
chr14:68210096(-) A-I      intronic
chr14:68226078(-) A-I      intronic
chr14:68198627(-) A-I      intronic
chr14:68198761(-) A-I      intronic
chr14:68246157(-) A-I      intronic
chr14:68224630(-) A-I      intronic
chr14:68226315(-) A-I      intronic
chr14:68198762(-) A-I      intronic
chr14:68225425(-) A-I      intronic
chr14:68225850(-) A-I      intronic
chr14:68209733(-) A-I      intronic
chr14:68225918(-) A-I      intronic
chr14:68225838(-) A-I      intronic
chr14:68224696(-) A-I      intronic
chr14:68246769(-) A-I      intronic
chr14:68209805(-) A-I      intronic
chr14:68227350(-) A-I      intronic
chr14:68246171(-) A-I      intronic
chr14:68225547(-) A-I      intronic
chr14:68246233(-) A-I      intronic
chr14:68224570(-) A-I      intronic
chr14:68225438(-) A-I      intronic
chr14:68226192(-) A-I      intronic
chr14:68224547(-) A-I      intronic
chr14:68225491(-) A-I      intronic
chr14:68199321(-) A-I      intronic
chr14:68226178(-) A-I      intronic
chr14:68225501(-) A-I      intronic
chr14:68246649(-) A-I      intronic
chr14:68224524(-) A-I      intronic
chr14:68199438(-) A-I      intronic
chr14:68246277(-) A-I      intronic
chr14:68246296(-) A-I      intronic
chr14:68225598(-) A-I      intronic
chr14:68246284(-) A-I      intronic
chr14:68226281(-) A-I      intronic
chr14:68246760(-) A-I      intronic
chr14:68224499(-) A-I      intronic
chr14:68212563(-) A-I      intronic
chr14:68261622(-) A-I      intronic
chr14:68225558(-) A-I      intronic
chr14:68225792(-) A-I      intronic
chr14:68198069(-) A-I      intronic
chr14:68261660(-) A-I      intronic
chr14:68198043(-) A-I      intronic
chr14:68197999(-) A-I      intronic
chr14:68197997(-) A-I      intronic
chr14:68269838(-) A-I      intronic
chr14:68209571(-) A-I      intronic
chr14:68204559(-) A-I      intronic
chr14:68227388(-) A-I      intronic
chr14:68199498(-) A-I      intronic
chr14:68226175(-) A-I      intronic
chr14:68246155(-) A-I      intronic
chr14:68210002(-) A-I      intronic
chr14:68259517(-) A-I      intronic
chr14:68269902(-) A-I      intronic
chr14:68209624(-) A-I      intronic
chr14:68226257(-) A-I      intronic
chr14:68246167(-) A-I      intronic
chr14:68225767(-) A-I      intronic
chr14:68225517(-) A-I      intronic
chr14:68225485(-) A-I      intronic
chr14:68220946(-) A-I      intronic
chr14:68225631(-) A-I      intronic
chr14:68246240(-) A-I      intronic
chr14:68209730(-) A-I      intronic
chr14:68209685(-) A-I      intronic
chr14:68209787(-) A-I      intronic
chr14:68198626(-) A-I      intronic
chr14:68246123(-) A-I      intronic
chr14:68225520(-) A-I      intronic
chr14:68227369(-) A-I      intronic
chr14:68246290(-) A-I      intronic
chr14:68204978(-) A-I      intronic
chr14:68246768(-) A-I      intronic
chr14:68210145(-) A-I      intronic
chr14:68246727(-) A-I      intronic
chr14:68209729(-) A-I      intronic
chr14:68224469(-) A-I      intronic
chr14:68209642(-) A-I      intronic
chr14:68203864(-) A-I      intronic
chr14:68225846(-) A-I      intronic
chr14:68209829(-) A-I      intronic
chr14:68203817(-) A-I      intronic
chr14:68225490(-) A-I      intronic
chr14:68225608(-) A-I      intronic
chr14:68210073(-) A-I      intronic
chr14:68226289(-) A-I      intronic
chr14:68199386(-) A-I      intronic
chr14:68273805(-) A-I      intronic
chr14:68225837(-) A-I      intronic
chr14:68209721(-) A-I      intronic
chr14:68225840(-) A-I      intronic
chr14:68259384(-) A-I      intronic
chr14:68225557(-) A-I      intronic
chr14:68209754(-) A-I      intronic
chr14:68225712(-) A-I      intronic
chr14:68210125(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED ZFYVE26
chr14:68262981(-) A-I intron -    15342557
chr14:68262986(-) A-I intron -    15342557
chr14:68263036(-) A-I intron -    15342557
chr14:68263039(-) A-I intron -    15342557
chr14:68263045(-) A-I intron -    15342557
chr14:68263091(-) A-I intron -    15342557
chr14:68263099(-) A-I intron -    15342557
chr14:68263100(-) A-I intron -    15342557
chr14:68263101(-) A-I intron -    15342557
chr14:68263105(-) A-I intron -    15342557
chr14:68263116(-) A-I intron -    15342557
chr14:68263118(-) A-I intron -    15342557
chr14:68263122(-) A-I intron -    15342557
chr14:68263126(-) A-I intron -    15342557
chr14:68263136(-) A-I intron -    15342557
chr14:68263150(-) A-I intron -    15342557
chr14:68263155(-) A-I intron -    15342557
chr14:68263169(-) A-I intron -    15342557
chr14:68263202(-) A-I intron -    15342557
chr14:68263424(-) A-I intron -    15342557
chr14:68263425(-) A-I intron -    15342557
chr14:68263477(-) A-I intron -    15342557
chr14:68263486(-) A-I intron -    15342557
chr14:68263503(-) A-I intron -    15342557
chr14:68263506(-) A-I intron -    15342557
chr14:68263582(-) A-I intron -    15342557
chr14:68263583(-) A-I intron -    15342557
chr14:68263617(-) A-I intron -    15342557
chr14:68263643(-) A-I intron -    15342557
chr14:68225520(-) A-G intron -    22484847
chr14:68263202(-) A-G intron -    22484847
chr14:68263583(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ZFYVE26
chr14:68213267-68213268(-) m6A 3'UTR//intron       27773535
chr14:68213306-68213307(-) m6A 3'UTR//intron       27773535
chr14:68213317-68213318(-) m6A 3'UTR//intron       27773535
chr14:68213345-68213346(-) m6A 3'UTR//intron       27773535
chr14:68213376-68213377(-) m6A 3'UTR//intron       24981863//27773535
chr14:68213406-68213407(-) m6A 3'UTR//intron       24981863//27773535
chr14:68213442-68213443(-) m6A 3'UTR//intron       24981863//27773535
chr14:68213499-68213500(-) m6A 3'UTR//intron       24981863//27773535
chr14:68213617-68213618(-) m6A 3'UTR//intron       24981863
chr14:68213625-68213626(-) m6A 3'UTR//intron       24981863
chr14:68213636-68213637(-) m6A 3'UTR//intron       24981863
chr14:68214988-68214989(-) m6A 3'UTR//exon//intron       24209618//25456834//24981863//27773535//27371828//22608085
chr14:68215018-68215019(-) m6A 3'UTR//exon//intron       24209618//25456834//24981863//27773535//27371828//22608085
chr14:68215059-68215060(-) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//28052920//27371828//22608085
chr14:68215130-68215131(-) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085
chr14:68215219-68215220(-) m6A 3'UTR//CDS//exon//intron       24209618//25456834//24981863//27371828//27773536//22575960//22608085
chr14:68215293-68215294(-) m6A 3'UTR//CDS//exon//intron       27773535//22608085
chr14:68215329-68215330(-) m6A 3'UTR//CDS//exon//intron       27773535
chr14:68227932-68227933(-) m6A 3'UTR//intron       24284625//27773535//22608085
chr14:68227939-68227940(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr14:68228006-68228007(-) m6A CDS//intron       24284625//25456834//24981863//27773535//22608085
chr14:68228026-68228027(-) m6A CDS//intron       24284625//25456834//24981863//27773535//22608085
chr14:68228070-68228071(-) m6A CDS//intron       24284625//25456834//24981863//27773535//22608085
chr14:68228076-68228077(-) m6A CDS//intron       24284625//25456834//24981863//27773535//22608085
chr14:68228203-68228204(-) m6A 3'UTR//CDS//exon       27773535
chr14:68228268-68228269(-) m6A 3'UTR//CDS//exon       27773535
chr14:68241780-68241781(-) m6A 3'UTR//CDS//exon       -
chr14:68244329-68244330(-) m6A 3'UTR//CDS//exon       27773535
chr14:68244914-68244915(-) m6A 3'UTR//CDS//exon       27773535
chr14:68249785-68249786(-) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//22608085
chr14:68249854-68249855(-) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//22608085
chr14:68249875-68249876(-) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//22608085
chr14:68249987-68249988(-) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//27773535//22608085
chr14:68250026-68250027(-) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//27773535//22608085
chr14:68250036-68250037(-) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//27773535//22608085
chr14:68250132-68250133(-) m6A 3'UTR//CDS//exon       24284625//24209618//27773535
chr14:68251849-68251850(-) m6A 3'UTR//CDS//exon       27773536
chr14:68251878-68251879(-) m6A 3'UTR//CDS//exon       27773536
chr14:68251888-68251889(-) m6A 3'UTR//CDS//exon       27773536
chr14:68251907-68251908(-) m6A 3'UTR//CDS//exon       27773536
chr14:68251985-68251986(-) m6A 3'UTR//CDS//exon       24284625//27773536
chr14:68262985-68262986(-) m6A exon//intron       24981863
chr14:68264406-68264407(-) m6A 3'UTR//CDS//exon       27371828//27773536
chr14:68264761-68264762(-) m6A 3'UTR//CDS//exon       27371828//27773536
chr14:68264815-68264816(-) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//27773535//27371828//27773536//22608085
chr14:68264971-68264972(-) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//27773535//22608085
chr14:68264978-68264979(-) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//27773535//22608085
chr14:68265014-68265015(-) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//27773535//22575960//22608085
chr14:68265060-68265061(-) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//27773535//22575960//22608085
chr14:68265185-68265186(-) m6A 3'UTR//CDS//exon       24284625//24981863//22608085
chr14:68265248-68265249(-) m6A 3'UTR//CDS//exon       24284625//24981863//22608085
chr14:68268842-68268843(-) m6A CDS//exon//intron       27773535
chr14:68268857-68268858(-) m6A CDS//exon//intron       27773535
chr14:68268866-68268867(-) m6A CDS//exon//intron       27773535
chr14:68268893-68268894(-) m6A CDS//exon//intron       27773535
chr14:68274255-68274256(-) m6A CDS//exon       25456834//27773536//22608085
chr14:68274274-68274275(-) m6A CDS//exon       25456834//24981863//27773536//22608085
chr14:68274310-68274311(-) m6A CDS//exon       25456834//24981863//27371828//27773536//22608085
chr14:68274330-68274331(-) m6A CDS//exon       25456834//24981863//27371828//22608085
chr14:68274416-68274417(-) m6A CDS//exon       25456834//24981863//27371828//22608085
chr14:68282742-68282743(-) m6A 5'UTR//exon       24981863
chr14:68283294-68283295(-) m6A 5'UTR//exon       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-33b-3p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
ZFYVE26
Chromatin K562 cells     -
Cytosol K562 cells     -
Exosome Blood     -
Membrane K562 cells     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Related Drug Information:


Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-33b-3p
Cisplatin 5702198       27559850

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-33b-3p
Interactor2: ZFYVE26

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence DIANA-microT
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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