Detail Information

Basic Information:


  VIRBase ID:  

HHID00012369

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-33b-3p:           VPS26C:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-33b-3p VPS26C
miRBase
Accession/Entrez ID
MIMAT0004811 10311
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - DCRA//DSCR3//DSCRA

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-33b-3p
rs1014636340 chr17:17813869    C/T
rs1175344913 chr17:17813860    C/T
rs1212055173 chr17:17813859    G/C
rs1333766161 chr17:17813870    G/A
rs1359466877 chr17:17813864    A/G
rs751021350 chr17:17813857    G/A
rs1272832890 chr17:17813873    G/A
rs1296048342 chr17:17813872    G/A
rs1399118390 chr17:17813874    C/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR VPS26C
chr21:38596709(-) A-I      3'UTR
chr21:38602418(-) A-I      intronic
chr21:38614028(-) A-I      intronic
chr21:38613931(-) A-I      intronic
chr21:38596714(-) A-I      3'UTR
chr21:38596748(-) A-I      3'UTR
chr21:38596747(-) A-I      3'UTR
chr21:38614040(-) A-I      intronic
chr21:38602440(-) A-I      intronic
chr21:38614037(-) A-I      intronic
chr21:38601076(-) A-I      intronic
chr21:38620269(-) A-I      intronic
chr21:38629364(-) A-I      intronic
chr21:38629376(-) A-I      intronic
chr21:38629381(-) A-I      intronic
chr21:38629389(-) A-I      intronic
chr21:38632761(-) A-I      intronic
chr21:38632762(-) A-I      intronic
chr21:38620219(-) A-I      intronic
chr21:38620221(-) A-I      intronic
chr21:38620253(-) A-I      intronic
chr21:38600413(-) A-I      intronic
chr21:38601111(-) A-I      intronic
chr21:38602219(-) A-I      intronic
chr21:38602276(-) A-I      intronic
chr21:38602277(-) A-I      intronic
chr21:38602278(-) A-I      intronic
chr21:38602283(-) A-I      intronic
chr21:38602293(-) A-I      intronic
chr21:38602300(-) A-I      intronic
chr21:38602349(-) A-I      intronic
chr21:38602351(-) A-I      intronic
chr21:38602364(-) A-I      intronic
chr21:38602386(-) A-I      intronic
chr21:38602411(-) A-I      intronic
chr21:38602414(-) A-I      intronic
chr21:38602441(-) A-I      intronic
chr21:38620289(-) A-I      intronic
chr21:38601186(-) A-I      intronic
chr21:38602405(-) A-I      intronic
chr21:38632778(-) A-I      intronic
chr21:38619116(-) A-I      intronic
chr21:38612698(-) A-I      intronic
chr21:38614047(-) A-I      intronic
chr21:38614001(-) A-I      intronic
chr21:38601145(-) A-I      intronic
chr21:38619335(-) A-I      intronic
chr21:38628340(-) A-I      intronic
chr21:38596590(-) A-I      3'UTR
chr21:38596661(-) A-I      3'UTR
chr21:38596589(-) A-I      3'UTR
chr21:38601221(-) A-I      intronic
chr21:38601212(-) A-I      intronic
chr21:38614011(-) A-I      intronic
chr21:38628410(-) A-I      intronic
chr21:38601287(-) A-I      intronic
chr21:38601116(-) A-I      intronic
chr21:38602400(-) A-I      intronic
chr21:38620209(-) A-I      intronic
chr21:38601251(-) A-I      intronic
chr21:38619278(-) A-I      intronic
chr21:38601210(-) A-I      intronic
chr21:38601315(-) A-I      intronic
chr21:38602401(-) A-I      intronic
chr21:38601167(-) A-I      intronic
chr21:38602454(-) A-I      intronic
chr21:38629234(-) A-I      intronic
chr21:38614023(-) A-I      intronic
chr21:38628261(-) A-I      intronic
chr21:38602371(-) A-I      intronic
chr21:38614082(-) A-I      intronic
chr21:38601128(-) A-I      intronic
chr21:38601115(-) A-I      intronic

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-33b-3p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
VPS26C
Chromatin K562 cells     -
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus Nasopharyngeal carcinoma cells     20498841

Related Drug Information:


Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-33b-3p

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-33b-3p
Interactor2: VPS26C

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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