Detail Information

Basic Information:


  VIRBase ID:  

HHID00012365

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-33b-3p:           ALG3:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-33b-3p ALG3
miRBase
Accession/Entrez ID		 MIMAT0004811 10195
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - CDG1D//CDGS4//CDGS6//D16Ertd36e//not//Not56//NOT56L

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-33b-3p
rs1014636340 chr17:17813869    C/T
rs1175344913 chr17:17813860    C/T
rs1212055173 chr17:17813859    G/C
rs1333766161 chr17:17813870    G/A
rs1359466877 chr17:17813864    A/G
rs751021350 chr17:17813857    G/A
rs1272832890 chr17:17813873    G/A
rs1296048342 chr17:17813872    G/A
rs1399118390 chr17:17813874    C/T

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ALG3
chr3:183960152-183960153(-) m6A 3'UTR       27773535
chr3:183960225-183960226(-) m6A 3'UTR       27773535
chr3:183960244-183960245(-) m6A 3'UTR       27773535
chr3:183960260-183960261(-) m6A 3'UTR//exon       27773535
chr3:183960279-183960280(-) m6A 3'UTR//exon       24284625//27773535
chr3:183960428-183960429(-) m6A 3'UTR//CDS//exon       24284625//27773535//22575960
chr3:183960815-183960816(-) m6A exon//intron       24981863//27773535
chr3:183960873-183960874(-) m6A exon//intron       27773535
chr3:183961686-183961687(-) m6A 3'UTR//CDS//exon       27773535
chr3:183961693-183961694(-) m6A 3'UTR//CDS//exon       27773535
chr3:183961752-183961753(-) m6A 3'UTR//CDS//exon       27773535
chr3:183962777-183962778(-) m6A exon//intron       27773535
chr3:183962891-183962892(-) m6A exon//intron       27773535
chr3:183966671-183966672(-) m6A CDS//exon//intron       25456834//24981863//26404942//27773536//22575960
chr3:183966791-183966792(-) m6A CDS//intron       25456834//24981863//27773535//22608085
chr3:183966846-183966847(-) m6A CDS//intron       24981863//27773535
chr3:183966886-183966887(-) m6A 5'UTR//intron       24981863//27773535
chr3:183966929-183966930(-) m6A 5'UTR//intron       24284625//24981863//27773535
chr3:183966942-183966943(-) m6A 5'UTR//intron       24284625//24981863//27773535
chr3:183966987-183966988(-) m6A 5'UTR//intron       24981863//27773535
chr3:183967070-183967071(-) m6A 5'UTR       24981863//27773535
chr3:183967079-183967080(-) m6A 5'UTR       24981863//27773535
chr3:183967104-183967105(-) m6A 5'UTR       24981863//27773535
chr3:183967238-183967239(-) m6A 5'UTR       24981863//27773535
chr3:183967298-183967299(-) m6A 5'UTR       24981863//27773535
chr3:183967310-183967311(-) m6A 5'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-33b-3p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
ALG3
Chromatin K562 cells     -
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleolus K562 cells     -
Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Related Drug Information:


Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-33b-3p
Cisplatin 5702198       27559850

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-33b-3p
Interactor2: ALG3

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence DIANA-microT
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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