Detail Information

Basic Information:


  VIRBase ID:  

HHID00012359

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-33b-3p:           PIGK:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-33b-3p PIGK
miRBase
Accession/Entrez ID		 MIMAT0004811 10026
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - GPI8//NEDHCAS

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-33b-3p
rs1014636340 chr17:17813869    C/T
rs1175344913 chr17:17813860    C/T
rs1212055173 chr17:17813859    G/C
rs1333766161 chr17:17813870    G/A
rs1359466877 chr17:17813864    A/G
rs751021350 chr17:17813857    G/A
rs1272832890 chr17:17813873    G/A
rs1296048342 chr17:17813872    G/A
rs1399118390 chr17:17813874    C/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR PIGK
chr1:77602047(-) A-I      intronic
chr1:77672805(-) A-I      intronic
chr1:77564090(-) A-I      intronic
chr1:77603562(-) A-I      intronic
chr1:77605777(-) A-I      intronic
chr1:77603545(-) A-I      intronic
chr1:77662486(-) A-I      intronic
chr1:77672826(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED PIGK
chr1:77662486(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase PIGK
chr1:77556403-77556404(-) m6A 3'UTR       27773535
chr1:77556424-77556425(-) m6A 3'UTR       27773535
chr1:77556440-77556441(-) m6A 3'UTR       27773535
chr1:77557942-77557943(-) m6A 3'UTR       24981863
chr1:77558020-77558021(-) m6A 3'UTR       24981863
chr1:77558027-77558028(-) m6A 3'UTR       24981863
chr1:77558057-77558058(-) m6A 3'UTR       24981863
chr1:77558093-77558094(-) m6A 3'UTR//CDS       24981863
chr1:77676162-77676163(-) m6A CDS//exon//intron       24284625//24981863
chr1:77685088-77685089(-) m6A 5'UTR//exon       24284625//24981863//27773535

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-33b-3p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
PIGK
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Membrane K562 cells     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HeLa-S3 cells|K562 cells     -
Ribosome HEK-293 cells     22199352
Ribosome Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-33b-3p
Cisplatin 5702198       27559850

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-33b-3p
Interactor2: PIGK

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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