Detail Information

Basic Information:


  VIRBase ID:  

HHID00012310

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-33b-3p:           DNAH17:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-33b-3p DNAH17
miRBase
Accession/Entrez ID		 MIMAT0004811 8632
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - DNAHL1//DNEL2//SPGF39

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-33b-3p
rs1014636340 chr17:17813869    C/T
rs1175344913 chr17:17813860    C/T
rs1212055173 chr17:17813859    G/C
rs1333766161 chr17:17813870    G/A
rs1359466877 chr17:17813864    A/G
rs751021350 chr17:17813857    G/A
rs1272832890 chr17:17813873    G/A
rs1296048342 chr17:17813872    G/A
rs1399118390 chr17:17813874    C/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR DNAH17
chr17:76478367(-) A-I      intronic
chr17:76469437(-) A-I      intronic
chr17:76465490(-) A-I      intronic
chr17:76469422(-) A-I      intronic
chr17:76469413(-) A-I      intronic
chr17:76478374(-) A-I      intronic
chr17:76465487(-) A-I      intronic
chr17:76427996(-) A-I      intronic
chr17:76426942(-) A-I      intronic
chr17:76422095(-) A-I      intronic
chr17:76465666(-) A-I      intronic
chr17:76439770(-) A-I      intronic
chr17:76549401(-) A-I      intronic
chr17:76428002(-) A-I      intronic
chr17:76507286(-) A-I      intronic
chr17:76466649(-) A-I      intronic
chr17:76444578(-) A-I      intronic
chr17:76443275(-) A-I      intronic
chr17:76439764(-) A-I      intronic
chr17:76516175(-) A-I      intronic
chr17:76428178(-) A-I      intronic
chr17:76438126(-) A-I      intronic
chr17:76438102(-) A-I      intronic
chr17:76428192(-) A-I      intronic
chr17:76438057(-) A-I      intronic
chr17:76428213(-) A-I      intronic
chr17:76436485(-) A-I      intronic
chr17:76453854(-) A-I      intronic
chr17:76466688(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED DNAH17
chr17:76444548(-) T-C intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase DNAH17
chr17:76433873-76433874(-) m6A CDS//exon       24284625
chr17:76433912-76433913(-) m6A CDS//exon       24284625
chr17:76449460-76449461(-) m6A CDS//exon       25456834
chr17:76449472-76449473(-) m6A CDS//exon       25456834
chr17:76449479-76449480(-) m6A CDS//exon       25456834
chr17:76449490-76449491(-) m6A CDS//exon       24284625//25456834
chr17:76449508-76449509(-) m6A CDS//exon       24284625//25456834
chr17:76450559-76450560(-) m6A CDS//exon       24284625//25456834
chr17:76450580-76450581(-) m6A CDS//exon       24284625//25456834
chr17:76450596-76450597(-) m6A CDS//exon       24284625//25456834
chr17:76457722-76457723(-) m6A CDS//exon       27773535
chr17:76472745-76472746(-) m6A CDS//intron       -
chr17:76480961-76480962(-) m6A CDS//exon       24284625
chr17:76481009-76481010(-) m6A CDS//exon       24284625
chr17:76481024-76481025(-) m6A CDS//exon       24284625
chr17:76481075-76481076(-) m6A CDS//exon       24284625
chr17:76481690-76481691(-) m6A CDS//exon       24284625//22575960
chr17:76481696-76481697(-) m6A CDS//exon       24284625//22575960
chr17:76481714-76481715(-) m6A CDS//exon       24284625//24209618//22575960
chr17:76481789-76481790(-) m6A CDS//exon       24284625//24209618//25456834//22575960
chr17:76481814-76481815(-) m6A CDS//exon       24284625//24209618//25456834//22575960
chr17:76482088-76482089(-) m6A CDS//exon       24284625//24209618//25456834//22575960
chr17:76482163-76482164(-) m6A CDS//exon       24284625//24209618//24981863//22575960
chr17:76482309-76482310(-) m6A CDS//exon       24284625//24209618//24981863//22575960
chr17:76482397-76482398(-) m6A CDS//exon       24284625//22575960
chr17:76482495-76482496(-) m6A CDS//exon       24284625
chr17:76486783-76486784(-) m6A CDS//exon       24284625//22575960
chr17:76486891-76486892(-) m6A CDS//exon       24284625//22575960
chr17:76487570-76487571(-) m6A CDS//exon       24284625
chr17:76487576-76487577(-) m6A CDS       24284625
chr17:76487627-76487628(-) m6A CDS       24284625
chr17:76488782-76488783(-) m6A CDS       24284625
chr17:76488788-76488789(-) m6A CDS       24284625
chr17:76488815-76488816(-) m6A CDS       24284625
chr17:76488825-76488826(-) m6A CDS       24284625
chr17:76490211-76490212(-) m6A CDS       24284625
chr17:76490690-76490691(-) m6A CDS       24284625//22575960
chr17:76490726-76490727(-) m6A CDS       24284625//22575960
chr17:76490737-76490738(-) m6A CDS       24284625//22575960
chr17:76490786-76490787(-) m6A CDS       24284625//22575960
chr17:76490813-76490814(-) m6A CDS       24284625//22575960
chr17:76491148-76491149(-) m6A CDS       24284625//22575960
chr17:76491974-76491975(-) m6A CDS       24284625
chr17:76496393-76496394(-) m6A CDS       24284625//22575960
chr17:76496450-76496451(-) m6A CDS       24284625
chr17:76496466-76496467(-) m6A CDS       24284625
chr17:76496475-76496476(-) m6A CDS       24284625
chr17:76497914-76497915(-) m6A CDS       24284625
chr17:76498241-76498242(-) m6A exon//intron       24284625
chr17:76498980-76498981(-) m6A CDS//exon       24284625
chr17:76499064-76499065(-) m6A CDS//exon       24284625

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-33b-3p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
DNAH17
Chromatin K562 cells     -
Cytosol HCC cell line (HepG2)     -
Exosome Blood     -
Nucleus HeLa-S3 cells     -

Related Drug Information:


Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-33b-3p
Cisplatin 5702198       27559850

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-33b-3p
Interactor2: DNAH17

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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