Detail Information

Basic Information:


  VIRBase ID:  

HHID00012045

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-130a-5p:           C3orf38:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-130a-5p C3orf38
miRBase
Accession/Entrez ID		 MIMAT0004593 285237
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-130a-5p
rs746985078 chr11:57641223    A/G
rs779670380 chr11:57641222    C/T
rs758215186 chr11:57641219    T/G

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase C3orf38
chr3:88198902-88198903(+) m6A 5'UTR       24981863
chr3:88198955-88198956(+) m6A 5'UTR       24981863
chr3:88198987-88198988(+) m6A 5'UTR       24981863
chr3:88199011-88199012(+) m6A 5'UTR       24981863
chr3:88199216-88199217(+) m6A CDS       24981863
chr3:88202422-88202423(+) m6A CDS//exon       22608085
chr3:88202509-88202510(+) m6A CDS       27773535//22608085
chr3:88202594-88202595(+) m6A CDS       24981863//27773535//22608085
chr3:88202601-88202602(+) m6A CDS       24981863//27773535//22608085
chr3:88205247-88205248(+) m6A CDS//intron       24284625//24209618//24981863//27773535//22575960//22608085
chr3:88205277-88205278(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr3:88205298-88205299(+) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr3:88205352-88205353(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr3:88205366-88205367(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr3:88205457-88205458(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr3:88205509-88205510(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr3:88205525-88205526(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr3:88205547-88205548(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr3:88205559-88205560(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr3:88205647-88205648(+) m6A 3'UTR//CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr3:88205658-88205659(+) m6A 3'UTR//CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr3:88205676-88205677(+) m6A 3'UTR//CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr3:88205767-88205768(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr3:88205774-88205775(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr3:88205800-88205801(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr3:88205810-88205811(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr3:88205820-88205821(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr3:88205886-88205887(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr3:88205968-88205969(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085
chr3:88205975-88205976(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085
chr3:88206090-88206091(+) m6A 3'UTR//exon       24284625//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-130a-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
C3orf38
Exosome Blood     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-130a-5p
Eloxatine 5310940 Drug interaction    RC00006934
5-Fluorouracil 3385 Drug interaction    RC00006933
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-130a-5p
Tamoxifen 2733526       30840279

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-130a-5p
Interactor2: C3orf38

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence DIANA-microT
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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