Detail Information

Basic Information:


  VIRBase ID:  

HHID00011924

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5908

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-130a-5p:           C6orf62:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-130a-5p C6orf62
miRBase
Accession/Entrez ID		 MIMAT0004593 81688
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - dJ30M3.2//Nbla00237//XTP12

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-130a-5p
rs746985078 chr11:57641223    A/G
rs779670380 chr11:57641222    C/T
rs758215186 chr11:57641219    T/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR C6orf62
chr6:24710669(-) A-I      intronic
chr6:24706896(-) A-I      intronic
chr6:24708857(-) A-I      intronic
chr6:24710626(-) A-I      intronic
chr6:24710609(-) A-I      intronic
chr6:24711098(-) A-I      intronic
chr6:24710551(-) A-I      intronic
chr6:24710546(-) A-I      intronic
chr6:24710541(-) A-I      intronic
chr6:24711061(-) A-I      intronic
chr6:24710521(-) A-I      intronic
chr6:24711022(-) A-I      intronic
chr6:24710665(-) A-I      intronic
chr6:24708838(-) A-I      intronic
chr6:24710670(-) A-I      intronic
chr6:24710691(-) A-I      intronic
chr6:24711055(-) A-I      intronic
chr6:24708767(-) A-I      intronic
chr6:24708754(-) A-I      intronic
chr6:24708730(-) A-I      intronic
chr6:24708726(-) A-I      intronic
chr6:24708127(-) A-I      intronic
chr6:24708120(-) A-I      intronic
chr6:24708095(-) A-I      intronic
chr6:24708064(-) A-I      intronic
chr6:24710758(-) A-I      intronic
chr6:24708062(-) A-I      intronic
chr6:24711108(-) A-I      intronic
chr6:24711119(-) A-I      intronic
chr6:24711206(-) A-I      intronic
chr6:24711812(-) A-I      intronic
chr6:24714976(-) A-I      intronic
chr6:24715020(-) A-I      intronic
chr6:24715022(-) A-I      intronic
chr6:24715023(-) A-I      intronic
chr6:24715832(-) A-I      intronic
chr6:24715857(-) A-I      intronic
chr6:24716039(-) A-I      intronic
chr6:24707021(-) A-I      intronic
chr6:24708050(-) A-I      intronic
chr6:24707992(-) A-I      intronic
chr6:24710603(-) A-I      intronic
chr6:24707989(-) A-I      intronic
chr6:24707988(-) A-I      intronic
chr6:24707788(-) A-I      intronic
chr6:24707689(-) A-I      intronic
chr6:24707078(-) A-I      intronic
chr6:24706991(-) A-I      intronic
chr6:24706945(-) A-I      intronic
chr6:24706922(-) A-I      intronic
chr6:24707132(-) A-I      intronic
chr6:24711144(-) A-I      intronic
chr6:24710729(-) A-I      intronic
chr6:24707686(-) A-I      intronic
chr6:24711151(-) A-I      intronic
chr6:24708139(-) A-I      intronic
chr6:24710982(-) A-I      intronic
chr6:24707750(-) A-I      intronic
chr6:24707676(-) A-I      intronic
chr6:24707790(-) A-I      intronic
chr6:24707681(-) A-I      intronic
chr6:24706992(-) A-I      intronic
chr6:24707834(-) A-I      intronic
chr6:24708822(-) A-I      intronic
chr6:24711182(-) A-I      intronic
chr6:24710591(-) A-I      intronic
chr6:24711163(-) A-I      intronic
chr6:24706970(-) A-I      intronic
chr6:24708650(-) A-I      intronic
chr6:24707858(-) A-I      intronic
chr6:24707660(-) A-I      intronic
chr6:24707668(-) A-I      intronic
chr6:24707852(-) A-I      intronic
chr6:24716069(-) A-I      intronic
chr6:24710622(-) A-I      intronic
chr6:24712395(-) A-I      intronic
chr6:24711187(-) A-I      intronic
chr6:24711009(-) A-I      intronic
chr6:24708042(-) A-I      intronic
chr6:24710764(-) A-I      intronic
chr6:24710615(-) A-I      intronic
chr6:24707860(-) A-I      intronic
chr6:24716070(-) A-I      intronic
chr6:24715040(-) A-I      intronic
chr6:24711120(-) A-I      intronic
chr6:24707846(-) A-I      intronic
chr6:24710983(-) A-I      intronic
chr6:24715120(-) A-I      intronic
chr6:24711096(-) A-I      intronic
chr6:24707757(-) A-I      intronic
chr6:24707975(-) A-I      intronic
chr6:24706895(-) A-I      intronic
chr6:24711125(-) A-I      intronic
chr6:24710586(-) A-I      intronic
chr6:24707714(-) A-I      intronic
chr6:24710590(-) A-I      intronic
chr6:24707987(-) A-I      intronic
chr6:24716046(-) A-I      intronic
chr6:24714917(-) A-I      intronic
chr6:24710605(-) A-I      intronic
chr6:24712879(-) A-I      intronic
chr6:24708821(-) A-I      intronic
chr6:24711076(-) A-I      intronic
chr6:24707805(-) A-I      intronic
chr6:24712425(-) A-I      intronic
chr6:24715954(-) A-I      intronic
chr6:24710970(-) A-I      intronic
chr6:24710765(-) A-I      intronic
chr6:24712442(-) A-I      intronic
chr6:24707742(-) A-I      intronic
chr6:24707764(-) A-I      intronic
chr6:24708117(-) A-I      intronic
chr6:24710773(-) A-I      intronic
chr6:24707000(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED C6orf62
chr6:24706905(-) A-I intron -    22327324
chr6:24707750(-) A-I intron -    21960545
chr6:24707790(-) A-I intron -    21960545
chr6:24708730(-) A-I intron -    21960545
chr6:24711096(-) A-I intron -    21960545
chr6:24706883(-) A-G intron -    22484847
chr6:24706905(-) A-G intron -    22484847
chr6:24706948(-) A-G intron -    22484847
chr6:24706992(-) A-G intron -    22484847
chr6:24706996(-) A-G intron -    22484847
chr6:24707131(-) A-G intron -    22484847
chr6:24707668(-) A-G intron -    22484847
chr6:24707714(-) A-G intron -    22484847
chr6:24707750(-) A-G intron -    22484847
chr6:24707769(-) A-G intron -    22484847
chr6:24707834(-) A-G intron -    22484847
chr6:24707860(-) A-G intron -    22484847
chr6:24707987(-) A-G intron -    22484847
chr6:24708042(-) A-G intron -    22484847
chr6:24708115(-) A-G intron -    22484847
chr6:24708117(-) A-G intron -    22484847
chr6:24708704(-) A-G intron -    22484847
chr6:24708722(-) A-G intron -    22484847
chr6:24708821(-) A-G intron -    22484847
chr6:24710513(-) C-T intron -    22484847
chr6:24710591(-) A-G intron -    22484847
chr6:24710605(-) A-G intron -    22484847
chr6:24710620(-) T-C intron -    22484847
chr6:24710657(-) A-G intron -    22484847
chr6:24710690(-) A-G intron -    22484847
chr6:24710695(-) A-G intron -    22484847
chr6:24710729(-) A-G intron -    22484847
chr6:24710970(-) A-G intron -    22484847
chr6:24711076(-) A-G intron -    22484847
chr6:24711096(-) A-G intron -    22484847
chr6:24711120(-) A-G intron -    22484847
chr6:24711125(-) A-G intron -    22484847
chr6:24711137(-) A-G intron -    22484847
chr6:24711144(-) A-G intron -    22484847
chr6:24711232(-) G-T intron -    22484847
chr6:24711237(-) G-T intron -    22484847
chr6:24711245(-) T-G intron -    22484847
chr6:24712844(-) T-C intron -    22484847
chr6:24712905(-) A-G intron -    22484847
chr6:24712918(-) G-T intron -    22484847
chr6:24715040(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase C6orf62
chr6:24705583-24705584(-) m6A 3'UTR       26404942
chr6:24705600-24705601(-) m6A 3'UTR       26404942
chr6:24705626-24705627(-) m6A 3'UTR       26404942
chr6:24705868-24705869(-) m6A 3'UTR       26404942
chr6:24705931-24705932(-) m6A 3'UTR       26404942//27773535//22608085
chr6:24706090-24706091(-) m6A 3'UTR       24284625//24209618//24981863//28052920//26404942//27773535//22575960//22608085
chr6:24706163-24706164(-) m6A 3'UTR       24284625//24209618//24981863//28052920//26404942//27773535//22575960//22608085
chr6:24706187-24706188(-) m6A 3'UTR       24284625//24209618//24981863//28052920//26404942//27773535//22575960//22608085
chr6:24706193-24706194(-) m6A 3'UTR       24284625//24209618//24981863//28052920//26404942//27773535//22575960//22608085
chr6:24706235-24706236(-) m6A 3'UTR       24284625//24209618//24981863//28052920//26404942//27773535//22575960//22608085
chr6:24706252-24706253(-) m6A 3'UTR       24284625//24209618//24981863//28052920//26404942//27773535//22575960//22608085
chr6:24706265-24706266(-) m6A 3'UTR       24284625//24209618//24981863//28052920//26404942//27773535//22575960//22608085
chr6:24706341-24706342(-) Am 3'UTR       -
chr6:24706427-24706428(-) m6A CDS       24284625//26404942
chr6:24719859-24719860(-) m6A 5'UTR//intron       22575960
chr6:24719886-24719887(-) m6A 5'UTR//intron       22575960
chr6:24719991-24719992(-) m6A 5'UTR//intron       22575960
chr6:24720048-24720049(-) m6A 5'UTR//intron       24284625//22575960
chr6:24720118-24720119(-) m6A 5'UTR//CDS       24284625
chr6:24720308-24720309(-) m6A 5'UTR       24284625
chr6:24720317-24720318(-) m6A 5'UTR       24284625//24209618//27773535
chr6:24720326-24720327(-) m6A 5'UTR       24284625//24209618//27773535
chr6:24720348-24720349(-) m6A 5'UTR       24284625//24209618//27773535
chr6:24720418-24720419(-) m6A 5'UTR       24284625//24209618//27773535
chr6:24720461-24720462(-) m6A 5'UTR       24284625//24209618//27773535//22575960
chr6:24720669-24720670(-) m6A 5'UTR       24284625//24209618//24981863//28052920//27773535//22575960
chr6:24720862-24720863(-) m6A 5'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr6:24720882-24720883(-) m6A 5'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr6:24721044-24721045(-) m6A 5'UTR       24284625//24209618//25456834//24981863//28052920//27371828//22575960//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-130a-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
C6orf62
Chromatin K562 cells     -
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus Nasopharyngeal carcinoma cells     20498841
Nucleus HCC cell line (HepG2)     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-130a-5p
Eloxatine 5310940 Drug interaction    RC00006934
5-Fluorouracil 3385 Drug interaction    RC00006933
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-130a-5p
Tamoxifen 2733526       30840279

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-130a-5p
Interactor2: C6orf62

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence DIANA-microT//miRDB
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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