Basic Information:

  VIRBase ID:  

HHID00011829

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-130a-5p:  MIMAT0004593          SBNO1:  NM_001167856     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-130a-5p	SBNO1
miRBase Accession/Entrez ID	MIMAT0004593	55206
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	MOP3//Sno

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-130a-5p	rs746985078 chr11:57641223    A/G rs779670380 chr11:57641222    C/T rs758215186 chr11:57641219    T/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	SBNO1	chr12:123799360(-) A-I      intronic chr12:123799390(-) A-I      intronic chr12:123799432(-) A-I      intronic chr12:123799371(-) A-I      intronic chr12:123783006(-) A-I      intronic chr12:123799395(-) A-I      intronic chr12:123783023(-) A-I      intronic chr12:123783052(-) A-I      intronic chr12:123799367(-) A-I      intronic chr12:123817230(-) A-I      intronic chr12:123825926(-) A-I      intronic chr12:123802775(-) A-I      intronic chr12:123826698(-) A-I      intronic chr12:123798548(-) A-I      intronic chr12:123817242(-) A-I      intronic chr12:123817252(-) A-I      intronic chr12:123817318(-) A-I      intronic chr12:123826735(-) A-I      intronic chr12:123825813(-) A-I      intronic chr12:123790247(-) A-I      intronic chr12:123825833(-) A-I      intronic chr12:123791500(-) A-I      intronic chr12:123781534(-) A-I      intronic chr12:123796560(-) A-I      intronic chr12:123825884(-) A-I      intronic chr12:123830314(-) A-I      intronic chr12:123807967(-) A-I      intronic chr12:123830345(-) A-I      intronic chr12:123781452(-) A-I      intronic chr12:123830499(-) A-I      intronic chr12:123781286(-) A-I      intronic chr12:123831018(-) A-I      intronic chr12:123825948(-) A-I      intronic chr12:123795270(-) A-I      intronic chr12:123832333(-) A-I      intronic chr12:123807296(-) A-I      intronic chr12:123807273(-) A-I      intronic chr12:123831938(-) A-I      intronic chr12:123807261(-) A-I      intronic chr12:123817210(-) A-I      intronic chr12:123807082(-) A-I      intronic chr12:123781139(-) A-I      intronic chr12:123781754(-) A-I      intronic chr12:123834653(-) A-I      intronic chr12:123831408(-) A-I      intronic chr12:123785172(-) A-I      intronic chr12:123802831(-) A-I      intronic chr12:123831022(-) A-I      intronic chr12:123788088(-) A-I      intronic chr12:123785359(-) A-I      intronic chr12:123797711(-) A-I      intronic chr12:123783567(-) A-I      intronic chr12:123798571(-) A-I      intronic chr12:123798519(-) A-I      intronic chr12:123831476(-) A-I      intronic chr12:123798444(-) A-I      intronic chr12:123796694(-) A-I      intronic chr12:123799536(-) A-I      intronic chr12:123802830(-) A-I      intronic chr12:123783734(-) A-I      intronic chr12:123785358(-) A-I      intronic chr12:123798509(-) A-I      intronic chr12:123797517(-) A-I      intronic chr12:123797530(-) A-I      intronic chr12:123798544(-) A-I      intronic chr12:123817234(-) A-I      intronic chr12:123797686(-) A-I      intronic chr12:123806756(-) A-I      intronic chr12:123808180(-) A-I      intronic chr12:123796559(-) A-I      intronic chr12:123807974(-) A-I      intronic chr12:123831493(-) A-I      intronic chr12:123783578(-) A-I      intronic chr12:123797533(-) A-I      intronic chr12:123788013(-) A-I      intronic chr12:123788103(-) A-I      intronic chr12:123831477(-) A-I      intronic chr12:123806979(-) A-I      intronic chr12:123808130(-) A-I      intronic chr12:123791614(-) A-I      intronic chr12:123825973(-) A-I      intronic chr12:123794935(-) A-I      intronic chr12:123833493(-) A-I      intronic chr12:123805583(-) A-I      intronic chr12:123797584(-) A-I      intronic chr12:123831587(-) A-I      intronic chr12:123834725(-) A-I      intronic chr12:123804106(-) A-I      intronic chr12:123804101(-) A-I      intronic chr12:123788077(-) A-I      intronic chr12:123781777(-) A-I      intronic chr12:123802795(-) A-I      intronic chr12:123826206(-) A-I      intronic chr12:123833425(-) A-I      intronic chr12:123803095(-) A-I      intronic chr12:123797507(-) A-I      intronic chr12:123782925(-) A-I      intronic chr12:123826348(-) A-I      intronic chr12:123783001(-) A-I      intronic chr12:123799517(-) A-I      intronic chr12:123798605(-) A-I      intronic chr12:123796348(-) A-I      intronic chr12:123811247(-) A-I      intronic chr12:123783032(-) A-I      intronic chr12:123785792(-) A-I      intronic chr12:123808058(-) A-I      intronic chr12:123785723(-) A-I      intronic chr12:123803091(-) A-I      intronic chr12:123811256(-) A-I      intronic chr12:123833424(-) A-I      intronic chr12:123798522(-) A-I      intronic chr12:123816904(-) A-I      intronic chr12:123785627(-) A-I      intronic chr12:123791624(-) A-I      intronic chr12:123790292(-) A-I      intronic chr12:123797488(-) A-I      intronic chr12:123785692(-) A-I      intronic chr12:123807209(-) A-I      intronic chr12:123816576(-) A-I      intronic chr12:123785774(-) A-I      intronic chr12:123802700(-) A-I      intronic chr12:123811682(-) A-I      intronic chr12:123807024(-) A-I      intronic chr12:123816579(-) A-I      intronic chr12:123791550(-) A-I      intronic chr12:123807116(-) A-I      intronic chr12:123815403(-) A-I      intronic chr12:123828264(-) A-I      intronic chr12:123785733(-) A-I      intronic chr12:123811645(-) A-I      intronic chr12:123785341(-) A-I      intronic chr12:123807329(-) A-I      intronic chr12:123825740(-) A-I      intronic chr12:123785778(-) A-I      intronic chr12:123788298(-) A-I      intronic chr12:123807038(-) A-I      intronic chr12:123781710(-) A-I      intronic chr12:123788084(-) A-I      intronic chr12:123785759(-) A-I      intronic chr12:123807270(-) A-I      intronic chr12:123802855(-) A-I      intronic chr12:123790149(-) A-I      intronic chr12:123807305(-) A-I      intronic chr12:123798555(-) A-I      intronic chr12:123809630(-) A-I      intronic chr12:123798545(-) A-I      intronic chr12:123797702(-) A-I      intronic chr12:123815415(-) A-I      intronic chr12:123807048(-) A-I      intronic chr12:123790132(-) A-I      intronic chr12:123783075(-) A-I      intronic chr12:123811800(-) A-I      intronic chr12:123782942(-) A-I      intronic chr12:123817387(-) A-I      intronic chr12:123785737(-) A-I      intronic chr12:123783671(-) A-I      intronic chr12:123806877(-) A-I      intronic chr12:123807072(-) A-I      intronic chr12:123829161(-) A-I      intronic chr12:123832108(-) A-I      intronic chr12:123803679(-) A-I      intronic chr12:123816668(-) A-I      intronic chr12:123828356(-) A-I      intronic chr12:123797135(-) A-I      intronic chr12:123816976(-) A-I      intronic chr12:123807117(-) A-I      intronic chr12:123834692(-) A-I      intronic chr12:123785423(-) A-I      intronic chr12:123796421(-) A-I      intronic chr12:123797096(-) A-I      intronic chr12:123802934(-) A-I      intronic chr12:123815462(-) A-I      intronic chr12:123783392(-) A-I      intronic chr12:123803659(-) A-I      intronic chr12:123783000(-) A-I      intronic chr12:123790116(-) A-I      intronic chr12:123797650(-) A-I      intronic chr12:123817292(-) A-I      intronic chr12:123781787(-) A-I      intronic chr12:123832346(-) A-I      intronic chr12:123808076(-) A-I      intronic chr12:123811605(-) A-I      intronic chr12:123786495(-) A-I      intronic chr12:123817016(-) A-I      intronic chr12:123815648(-) A-I      intronic chr12:123785314(-) A-I      intronic chr12:123786622(-) A-I      intronic chr12:123797667(-) A-I      intronic chr12:123796447(-) A-I      intronic chr12:123834609(-) A-I      intronic chr12:123796096(-) A-I      intronic chr12:123788638(-) A-I      intronic chr12:123796629(-) A-I      intronic chr12:123816591(-) A-I      intronic chr12:123791741(-) A-I      intronic chr12:123818998(-) A-I      intronic chr12:123795314(-) A-I      intronic chr12:123802736(-) A-I      intronic chr12:123799015(-) A-I      intronic chr12:123833771(-) A-I      intronic chr12:123827741(-) A-I      intronic chr12:123785083(-) A-I      intronic chr12:123806752(-) A-I      intronic chr12:123817290(-) A-I      intronic chr12:123811610(-) A-I      intronic chr12:123817017(-) A-I      intronic chr12:123795309(-) A-I      intronic chr12:123802903(-) A-I      intronic chr12:123781278(-) A-I      intronic chr12:123811761(-) A-I      intronic chr12:123808173(-) A-I      intronic chr12:123827617(-) A-I      intronic chr12:123784824(-) A-I      intronic chr12:123783454(-) A-I      intronic chr12:123785719(-) A-I      intronic chr12:123826177(-) A-I      intronic chr12:123784128(-) A-I      intronic chr12:123826711(-) A-I      intronic chr12:123803579(-) A-I      intronic chr12:123830501(-) A-I      intronic chr12:123807937(-) A-I      intronic chr12:123833677(-) A-I      intronic chr12:123828355(-) A-I      intronic chr12:123808174(-) A-I      intronic chr12:123828303(-) A-I      intronic chr12:123785683(-) A-I      intronic chr12:123827761(-) A-I      intronic chr12:123788547(-) A-I      intronic chr12:123817293(-) A-I      intronic chr12:123803717(-) A-I      intronic chr12:123803034(-) A-I      intronic chr12:123833719(-) A-I      intronic chr12:123807370(-) A-I      intronic chr12:123809462(-) A-I      intronic chr12:123785420(-) A-I      intronic chr12:123834338(-) A-I      intronic chr12:123829136(-) A-I      intronic chr12:123828222(-) A-I      intronic chr12:123797674(-) A-I      intronic chr12:123782899(-) A-I      intronic chr12:123788926(-) A-I      intronic chr12:123802815(-) A-I      intronic chr12:123803684(-) A-I      intronic chr12:123786390(-) A-I      intronic chr12:123796403(-) A-I      intronic chr12:123785473(-) A-I      intronic chr12:123791474(-) A-I      intronic chr12:123808066(-) A-I      intronic chr12:123799343(-) A-I      intronic chr12:123828288(-) A-I      intronic chr12:123807208(-) A-I      intronic chr12:123807380(-) A-I      intronic chr12:123791740(-) A-I      intronic chr12:123833421(-) A-I      intronic chr12:123825909(-) A-I      intronic chr12:123826174(-) A-I      intronic chr12:123811692(-) A-I      intronic chr12:123832354(-) A-I      intronic chr12:123817018(-) A-I      intronic chr12:123790159(-) A-I      intronic chr12:123785670(-) A-I      intronic chr12:123815353(-) A-I      intronic chr12:123785824(-) A-I      intronic chr12:123797175(-) A-I      intronic chr12:123796533(-) A-I      intronic chr12:123783600(-) A-I      intronic chr12:123798470(-) A-I      intronic chr12:123833938(-) A-I      intronic chr12:123781724(-) A-I      intronic chr12:123806818(-) A-I      intronic chr12:123797668(-) A-I      intronic chr12:123807965(-) A-I      intronic chr12:123806939(-) A-I      intronic chr12:123786623(-) A-I      intronic chr12:123785344(-) A-I      intronic chr12:123807027(-) A-I      intronic chr12:123807196(-) A-I      intronic chr12:123782946(-) A-I      intronic chr12:123802929(-) A-I      intronic chr12:123797014(-) A-I      intronic chr12:123797093(-) A-I      intronic chr12:123786503(-) A-I      intronic chr12:123788324(-) A-I      intronic chr12:123817507(-) A-I      intronic chr12:123830483(-) A-I      intronic chr12:123829296(-) A-I      intronic chr12:123783057(-) A-I      intronic chr12:123817291(-) A-I      intronic chr12:123783024(-) A-I      intronic chr12:123826347(-) A-I      intronic chr12:123817317(-) A-I      intronic chr12:123782919(-) A-I      intronic chr12:123807364(-) A-I      intronic chr12:123816977(-) A-I      intronic chr12:123832240(-) A-I      intronic chr12:123785015(-) A-I      intronic chr12:123799403(-) A-I      intronic chr12:123791641(-) A-I      intronic chr12:123815606(-) A-I      intronic chr12:123803649(-) A-I      intronic chr12:123797663(-) A-I      intronic chr12:123811398(-) A-I      intronic chr12:123806944(-) A-I      intronic chr12:123828267(-) A-I      intronic chr12:123825874(-) A-I      intronic chr12:123803680(-) A-I      intronic chr12:123806745(-) A-I      intronic chr12:123781529(-) A-I      intronic chr12:123833848(-) A-I      intronic chr12:123811362(-) A-I      intronic chr12:123819037(-) A-I      intronic chr12:123786379(-) A-I      intronic chr12:123815375(-) A-I      intronic chr12:123832054(-) A-I      intronic chr12:123803746(-) A-I      intronic chr12:123817482(-) A-I      intronic chr12:123806777(-) A-I      intronic chr12:123791485(-) A-I      intronic chr12:123796719(-) A-I      intronic chr12:123797137(-) A-I      intronic chr12:123811438(-) A-I      intronic chr12:123783726(-) A-I      intronic chr12:123807383(-) A-I      intronic chr12:123785758(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	SBNO1	chr12:123782899(-) A-G intron -    22484847 chr12:123783000(-) A-G intron -    22484847 chr12:123799015(-) A-G intron -    22484847 chr12:123806818(-) A-G intron -    22484847 chr12:123807937(-) A-G intron -    22484847 chr12:123781529(-) A-G intron -    22484847 chr12:123781710(-) A-G intron -    22484847 chr12:123781724(-) A-G intron -    22484847 chr12:123783024(-) A-G intron -    22484847 chr12:123783057(-) A-G intron -    22484847 chr12:123783726(-) A-G intron -    22484847 chr12:123784128(-) A-G intron -    22484847 chr12:123785314(-) A-G intron -    22484847 chr12:123785341(-) A-G intron -    22484847 chr12:123785420(-) A-G intron -    22484847 chr12:123785423(-) A-G intron -    22484847 chr12:123785473(-) A-G intron -    22484847 chr12:123785719(-) A-G intron -    22484847 chr12:123785758(-) A-G intron -    22484847 chr12:123785759(-) A-G intron -    22484847 chr12:123785774(-) A-G intron -    22484847 chr12:123785778(-) A-G intron -    22484847 chr12:123785824(-) A-G intron -    22484847 chr12:123788084(-) A-G intron -    22484847 chr12:123788324(-) A-G intron -    22484847 chr12:123788638(-) A-G intron -    22484847 chr12:123788926(-) A-G intron -    22484847 chr12:123790159(-) A-G intron -    22484847 chr12:123791741(-) A-G intron -    22484847 chr12:123796096(-) A-G intron -    22484847 chr12:123797488(-) A-G intron -    22484847 chr12:123797663(-) A-G intron -    22484847 chr12:123797667(-) A-G intron -    22484847 chr12:123797668(-) A-G intron -    22484847 chr12:123797674(-) A-G intron -    22484847 chr12:123798545(-) A-G intron -    22484847 chr12:123802815(-) A-G intron -    22484847 chr12:123802855(-) A-G intron -    22484847 chr12:123802903(-) A-G intron -    22484847 chr12:123802929(-) A-G intron -    22484847 chr12:123802934(-) A-G intron -    22484847 chr12:123803659(-) A-G intron -    22484847 chr12:123804217(-) T-C intron -    22484847 chr12:123806877(-) A-G intron -    22484847 chr12:123807038(-) A-G intron -    22484847 chr12:123807048(-) A-G intron -    22484847 chr12:123807209(-) A-G intron -    22484847 chr12:123807270(-) A-G intron -    22484847 chr12:123807305(-) A-G intron -    22484847 chr12:123807370(-) A-G intron -    22484847 chr12:123807380(-) A-G intron -    22484847 chr12:123807965(-) A-G intron -    22484847 chr12:123811362(-) A-G intron -    22484847 chr12:123811398(-) A-G intron -    22484847 chr12:123811438(-) A-G intron -    22484847 chr12:123811800(-) A-G intron -    22484847 chr12:123815462(-) A-G intron -    22484847 chr12:123816976(-) A-G intron -    22484847 chr12:123816977(-) A-G intron -    22484847 chr12:123817016(-) A-G intron -    22484847 chr12:123817017(-) A-G intron -    22484847 chr12:123817018(-) A-G intron -    22484847 chr12:123817290(-) A-G intron -    22484847 chr12:123817291(-) A-G intron -    22484847 chr12:123817292(-) A-G intron -    22484847 chr12:123817293(-) A-G intron -    22484847 chr12:123817317(-) A-G intron -    22484847 chr12:123817515(-) C-G intron -    22484847 chr12:123825874(-) A-G intron -    22484847 chr12:123825909(-) A-G intron -    22484847 chr12:123827617(-) A-G intron -    22484847 chr12:123827761(-) A-G intron -    22484847 chr12:123828222(-) A-G intron -    22484847 chr12:123829161(-) A-G intron -    22484847 chr12:123830483(-) A-G intron -    22484847 chr12:123832354(-) A-G intron -    22484847 chr12:123832939(-) C-T intron -    22484847 chr12:123833421(-) A-G intron -    22484847 chr12:123833938(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	SBNO1	chr12:123775266-123775267(-) m6A 3'UTR       27371828 chr12:123775311-123775312(-) m6A 3'UTR       27371828 chr12:123775317-123775318(-) m6A 3'UTR       27371828 chr12:123775380-123775381(-) m6A 3'UTR       27371828 chr12:123776333-123776334(-) m6A 3'UTR       24981863 chr12:123779014-123779015(-) m6A 3'UTR       27773535 chr12:123779065-123779066(-) m6A 3'UTR       27773535 chr12:123779139-123779140(-) m6A 3'UTR       27773535 chr12:123780293-123780294(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085 chr12:123780316-123780317(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085 chr12:123780382-123780383(-) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//27371828//22608085 chr12:123780450-123780451(-) m6A 3'UTR       24284625//24209618//24981863//27773535//27371828//22608085 chr12:123780508-123780509(-) m6A CDS       24284625//24209618//24981863//27371828//22608085 chr12:123780539-123780540(-) m6A CDS       24284625//24209618//24981863//27371828//22608085 chr12:123789209-123789210(-) m6A CDS       24981863 chr12:123789247-123789248(-) m6A CDS       24981863 chr12:123789258-123789259(-) m6A CDS       24981863 chr12:123793886-123793887(-) m6A CDS       24981863 chr12:123800106-123800107(-) m6A CDS       - chr12:123800136-123800137(-) m6A CDS       - chr12:123800148-123800149(-) m6A CDS       - chr12:123800188-123800189(-) m6A CDS       - chr12:123805005-123805006(-) m6A CDS       24981863 chr12:123805017-123805018(-) m6A CDS       24981863 chr12:123805042-123805043(-) m6A CDS       24981863 chr12:123805379-123805380(-) m6A CDS       24981863//27773535 chr12:123805391-123805392(-) m6A CDS       24981863//27773535 chr12:123806149-123806150(-) m6A CDS       24981863//27773535 chr12:123820968-123820969(-) m6A CDS       24981863//27773535 chr12:123821008-123821009(-) m6A CDS       24981863//27773535 chr12:123829850-123829851(-) m6A CDS       24284625//24981863//26404942//27773535//22608085 chr12:123829859-123829860(-) m6A CDS       24284625//24981863//26404942//27773535//22608085 chr12:123829905-123829906(-) m6A CDS       24284625//24981863//26404942//27773535//22608085 chr12:123829978-123829979(-) m6A CDS       24284625//24981863//26404942//27773535//22608085 chr12:123830005-123830006(-) m6A CDS       24284625//24981863//26404942//27773535 chr12:123830032-123830033(-) m6A CDS       24284625//24981863//27773535 chr12:123832607-123832608(-) m6A CDS       27773535 chr12:123832614-123832615(-) m6A CDS       27773535 chr12:123832620-123832621(-) m6A CDS       27773535 chr12:123832643-123832644(-) m6A CDS       27773535 chr12:123849296-123849297(-) m6A 5'UTR       25456834//24981863//27371828

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-130a-5p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
	SBNO1	Chromatin K562 cells     - Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol K562 cells     - Exosome Blood     - Membrane HCC cell line (HepG2)|K562 cells     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus Nasopharyngeal carcinoma cells     20498841 Nucleus Colon cancer cells     24393600 Nucleus K562 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-130a-5p	Eloxatine 5310940 Drug interaction    RC00006934 5-Fluorouracil 3385 Drug interaction    RC00006933

Resource	Symbol	Drug Name	PubChem ID	PMID
NoncoRNA	hsa-miR-130a-5p	Tamoxifen 2733526       30840279

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-130a-5p
Interactor2: SBNO1

Evidence Support:

Weak-Evidence	RNA-Seq
Prediction-Evidence	DIANA-microT
Support Database	ViRBase

References:

PMID	31570108	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	ARPE-19 human RPE cells	Interactor2 expression	None
Description	Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).