Basic Information:

  VIRBase ID:  

HHID00009749

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-29b-1-5p:  MIMAT0004514          BACE1:  NM_138972     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-29b-1-5p	BACE1
miRBase Accession/Entrez ID	MIMAT0004514	23621
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	ASP2//BACE//HSPC104

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-29b-1-5p	rs1189550020 chr7:130877522    G/GA rs1554489373 chr7:130877519    T/C rs1554489375 chr7:130877520    A/C rs782109811 chr7:130877509    TA/T rs778204762 chr7:130877526    C/A rs778204762 chr7:130877526    C/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	BACE1	chr11:117156629(-) A-I      3'UTR chr11:117157654(-) A-I      3'UTR chr11:117157651(-) A-I      3'UTR chr11:117156680(-) A-I      3'UTR chr11:117177267(-) A-I      intronic chr11:117157609(-) A-I      3'UTR chr11:117156655(-) A-I      3'UTR chr11:117156666(-) A-I      3'UTR chr11:117169754(-) A-I      5'UTR chr11:117169666(-) A-I      5'UTR chr11:117157650(-) A-I      3'UTR chr11:117179485(-) A-I      intronic chr11:117157646(-) A-I      3'UTR chr11:117157639(-) A-I      3'UTR chr11:117169715(-) A-I      5'UTR chr11:117157638(-) A-I      3'UTR chr11:117156632(-) A-I      3'UTR chr11:117157655(-) A-I      3'UTR chr11:117157659(-) A-I      3'UTR chr11:117157635(-) A-I      3'UTR chr11:117157633(-) A-I      3'UTR chr11:117157629(-) A-I      3'UTR chr11:117156679(-) A-I      3'UTR chr11:117157628(-) A-I      3'UTR chr11:117177239(-) A-I      intronic chr11:117157668(-) A-I      3'UTR chr11:117177333(-) A-I      intronic chr11:117177307(-) A-I      intronic chr11:117177294(-) A-I      intronic chr11:117177279(-) A-I      intronic chr11:117157625(-) A-I      3'UTR chr11:117157623(-) A-I      3'UTR chr11:117157620(-) A-I      3'UTR chr11:117156628(-) A-I      3'UTR chr11:117156633(-) A-I      3'UTR chr11:117180722(-) A-I      intronic chr11:117179587(-) A-I      intronic chr11:117165519(-) A-I      intronic chr11:117179586(-) A-I      intronic chr11:117178232(-) A-I      intronic chr11:117177444(-) A-I      intronic chr11:117175780(-) A-I      intronic chr11:117173047(-) A-I      intronic chr11:117173023(-) A-I      intronic chr11:117165544(-) A-I      intronic chr11:117180212(-) A-I      intronic chr11:117165174(-) A-I      intronic chr11:117165169(-) A-I      intronic chr11:117177405(-) A-I      intronic chr11:117165155(-) A-I      intronic chr11:117164998(-) A-I      intronic chr11:117164968(-) A-I      intronic chr11:117164961(-) A-I      intronic chr11:117173479(-) A-I      intronic chr11:117175747(-) A-I      intronic chr11:117177358(-) A-I      intronic chr11:117165035(-) A-I      intronic chr11:117180199(-) A-I      intronic chr11:117184353(-) A-I      intronic chr11:117181976(-) A-I      intronic chr11:117175797(-) A-I      intronic chr11:117179545(-) A-I      intronic chr11:117180762(-) A-I      intronic chr11:117175819(-) A-I      intronic chr11:117181213(-) A-I      intronic chr11:117173549(-) A-I      intronic chr11:117180736(-) A-I      intronic chr11:117180749(-) A-I      intronic chr11:117179431(-) A-I      intronic chr11:117177322(-) A-I      intronic chr11:117184358(-) A-I      intronic chr11:117180771(-) A-I      intronic chr11:117181310(-) A-I      intronic chr11:117184247(-) A-I      intronic chr11:117178300(-) A-I      intronic chr11:117176562(-) A-I      intronic chr11:117181356(-) A-I      intronic chr11:117181854(-) A-I      intronic chr11:117165109(-) A-I      intronic chr11:117181977(-) A-I      intronic chr11:117182525(-) A-I      intronic chr11:117179415(-) A-I      intronic chr11:117182530(-) A-I      intronic chr11:117184350(-) A-I      intronic chr11:117184357(-) A-I      intronic chr11:117175846(-) A-I      intronic chr11:117182495(-) A-I      intronic chr11:117165370(-) A-I      intronic chr11:117168869(-) A-I      5'UTR chr11:117168224(-) A-I      5'UTR chr11:117168870(-) A-I      5'UTR chr11:117169611(-) A-I      5'UTR chr11:117168164(-) A-I      5'UTR chr11:117169618(-) A-I      5'UTR chr11:117169759(-) A-I      5'UTR chr11:117169690(-) A-I      5'UTR chr11:117168208(-) A-I      5'UTR chr11:117168133(-) A-I      5'UTR chr11:117168906(-) A-I      5'UTR chr11:117168254(-) A-I      5'UTR chr11:117168173(-) A-I      5'UTR chr11:117168079(-) A-I      5'UTR chr11:117168971(-) A-I      5'UTR chr11:117169556(-) A-I      5'UTR chr11:117168188(-) A-I      5'UTR chr11:117168883(-) A-I      5'UTR chr11:117168212(-) A-I      5'UTR chr11:117168214(-) A-I      5'UTR chr11:117168748(-) A-I      5'UTR chr11:117168936(-) A-I      5'UTR chr11:117172927(-) A-I      intronic chr11:117177458(-) A-I      intronic chr11:117173557(-) A-I      intronic chr11:117181946(-) A-I      intronic chr11:117173043(-) A-I      intronic chr11:117181937(-) A-I      intronic chr11:117182534(-) A-I      intronic chr11:117180234(-) A-I      intronic chr11:117180740(-) A-I      intronic chr11:117177289(-) A-I      intronic chr11:117165160(-) A-I      intronic chr11:117179503(-) A-I      intronic chr11:117173436(-) A-I      intronic chr11:117182442(-) A-I      intronic chr11:117183343(-) A-I      intronic chr11:117175728(-) A-I      intronic chr11:117184600(-) A-I      intronic chr11:117181355(-) A-I      intronic chr11:117173489(-) A-I      intronic chr11:117172965(-) A-I      intronic chr11:117173419(-) A-I      intronic chr11:117183367(-) A-I      intronic chr11:117180800(-) A-I      intronic chr11:117165378(-) A-I      intronic chr11:117173435(-) A-I      intronic chr11:117165726(-) A-I      intronic chr11:117164967(-) A-I      intronic chr11:117181432(-) A-I      intronic chr11:117181837(-) A-I      intronic chr11:117184179(-) A-I      intronic chr11:117165395(-) A-I      intronic chr11:117173342(-) A-I      intronic chr11:117180848(-) A-I      intronic chr11:117178231(-) A-I      intronic chr11:117175807(-) A-I      intronic chr11:117179500(-) A-I      intronic chr11:117177306(-) A-I      intronic chr11:117181275(-) A-I      intronic chr11:117182429(-) A-I      intronic chr11:117173381(-) A-I      intronic chr11:117177521(-) A-I      intronic chr11:117179409(-) A-I      intronic chr11:117181274(-) A-I      intronic chr11:117184386(-) A-I      intronic chr11:117164962(-) A-I      intronic chr11:117177411(-) A-I      intronic chr11:117184289(-) A-I      intronic chr11:117173040(-) A-I      intronic chr11:117181931(-) A-I      intronic chr11:117184275(-) A-I      intronic chr11:117180912(-) A-I      intronic chr11:117179482(-) A-I      intronic chr11:117172884(-) A-I      intronic chr11:117178323(-) A-I      intronic chr11:117165333(-) A-I      intronic chr11:117165070(-) A-I      intronic chr11:117165588(-) A-I      intronic chr11:117165452(-) A-I      intronic chr11:117177399(-) A-I      intronic chr11:117172793(-) A-I      intronic chr11:117182627(-) A-I      intronic chr11:117176630(-) A-I      intronic chr11:117165518(-) A-I      intronic chr11:117181947(-) A-I      intronic chr11:117172911(-) A-I      intronic chr11:117181222(-) A-I      intronic chr11:117183319(-) A-I      intronic chr11:117177464(-) A-I      intronic chr11:117178049(-) A-I      intronic chr11:117165412(-) A-I      intronic chr11:117179387(-) A-I      intronic chr11:117165030(-) A-I      intronic chr11:117175781(-) A-I      intronic chr11:117180224(-) A-I      intronic chr11:117180785(-) A-I      intronic chr11:117178063(-) A-I      intronic chr11:117165501(-) A-I      intronic chr11:117182521(-) A-I      intronic chr11:117172973(-) A-I      intronic chr11:117178125(-) A-I      intronic chr11:117165237(-) A-I      intronic chr11:117179547(-) A-I      intronic chr11:117165061(-) A-I      intronic chr11:117177392(-) A-I      intronic chr11:117165057(-) A-I      intronic chr11:117181950(-) A-I      intronic chr11:117165029(-) A-I      intronic chr11:117184288(-) A-I      intronic chr11:117165343(-) A-I      intronic chr11:117178192(-) A-I      intronic chr11:117176507(-) A-I      intronic chr11:117179447(-) A-I      intronic chr11:117182485(-) A-I      intronic chr11:117181842(-) A-I      intronic chr11:117165356(-) A-I      intronic chr11:117165434(-) A-I      intronic chr11:117165115(-) A-I      intronic chr11:117165161(-) A-I      intronic chr11:117177480(-) A-I      intronic chr11:117172880(-) A-I      intronic chr11:117164959(-) A-I      intronic chr11:117175694(-) A-I      intronic chr11:117169673(-) A-I      5'UTR chr11:117168855(-) A-I      5'UTR chr11:117169646(-) A-I      5'UTR chr11:117169637(-) A-I      5'UTR chr11:117169801(-) A-I      5'UTR chr11:117169768(-) A-I      5'UTR chr11:117168783(-) A-I      5'UTR chr11:117168800(-) A-I      5'UTR chr11:117168935(-) A-I      5'UTR chr11:117168910(-) A-I      5'UTR chr11:117168187(-) A-I      5'UTR chr11:117169594(-) A-I      5'UTR chr11:117169589(-) A-I      5'UTR chr11:117168833(-) A-I      5'UTR chr11:117168326(-) A-I      5'UTR chr11:117168801(-) A-I      5'UTR chr11:117168909(-) A-I      5'UTR chr11:117168284(-) A-I      5'UTR chr11:117168878(-) A-I      5'UTR chr11:117168826(-) A-I      5'UTR chr11:117168253(-) A-I      5'UTR chr11:117168761(-) A-I      5'UTR chr11:117168292(-) A-I      5'UTR chr11:117169686(-) A-I      5'UTR chr11:117169569(-) A-I      5'UTR chr11:117168101(-) A-I      5'UTR

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	BACE1	chr11:117156413-117156414(-) m6A 3'UTR       27773535 chr11:117156472-117156473(-) m6A 3'UTR       24981863//27773535 chr11:117156488-117156489(-) m6A 3'UTR       24981863//27773535 chr11:117156511-117156512(-) m6A 3'UTR       24981863//27773535 chr11:117156535-117156536(-) m6A 3'UTR       24981863//27773535 chr11:117156568-117156569(-) m6A 3'UTR       24981863//27773535 chr11:117156609-117156610(-) m6A 3'UTR       24981863//27773535 chr11:117156625-117156626(-) m6A 3'UTR       24981863//27773535 chr11:117156644-117156645(-) m6A 3'UTR       24981863//27773535 chr11:117156686-117156687(-) m6A 3'UTR       24981863//27773535 chr11:117156713-117156714(-) m6A 3'UTR       24981863 chr11:117156721-117156722(-) m6A 3'UTR       24981863 chr11:117156910-117156911(-) m6A 3'UTR       27773535 chr11:117156951-117156952(-) m6A 3'UTR       27773535 chr11:117158231-117158232(-) m6A 3'UTR       27773535 chr11:117158283-117158284(-) m6A 3'UTR       27773535 chr11:117158317-117158318(-) m6A 3'UTR       27773535 chr11:117158379-117158380(-) m6A 3'UTR       27773535 chr11:117158388-117158389(-) m6A 3'UTR       27773535 chr11:117158405-117158406(-) m6A 3'UTR       27773535 chr11:117158426-117158427(-) m6A 3'UTR       27773535 chr11:117158433-117158434(-) m6A 3'UTR       27773535 chr11:117158464-117158465(-) m6A 3'UTR       27773535 chr11:117158541-117158542(-) m6A 3'UTR       24284625 chr11:117158550-117158551(-) m6A 3'UTR       24284625 chr11:117158644-117158645(-) m6A 3'UTR       24284625 chr11:117158740-117158741(-) m6A 3'UTR       24284625 chr11:117159603-117159604(-) m6A 3'UTR       24981863//27773535 chr11:117159632-117159633(-) m6A 3'UTR       24981863//27773535 chr11:117159669-117159670(-) m6A 3'UTR       24284625//24981863//27773535//22608085 chr11:117159733-117159734(-) m6A 3'UTR       24284625//24981863//27773535//22608085 chr11:117159781-117159782(-) m6A 3'UTR       24284625//24981863//27773535//22608085 chr11:117159790-117159791(-) m6A 3'UTR       24284625//24981863//27773535//22608085 chr11:117159796-117159797(-) m6A 3'UTR       24284625//24981863//27773535//22608085 chr11:117159864-117159865(-) m6A 3'UTR       24284625//24981863//27773535//22608085 chr11:117159990-117159991(-) m6A 3'UTR       24284625//24981863//27773535//22575960//22608085 chr11:117160003-117160004(-) m6A 3'UTR       24284625//25456834//24981863//27773535//22575960//22608085 chr11:117160088-117160089(-) m6A 3'UTR       24284625//25456834//24981863//27773535//22575960//22608085 chr11:117160104-117160105(-) m6A 3'UTR       24284625//25456834//24981863//27773535//22575960//22608085 chr11:117160173-117160174(-) m6A 3'UTR       24284625//25456834//24981863//27773535//22575960//22608085 chr11:117160207-117160208(-) m6A 3'UTR       24284625//25456834//24981863//27773535//22575960//22608085 chr11:117160245-117160246(-) m6A 3'UTR       24284625//25456834//24981863//27773535//22575960//22608085 chr11:117160439-117160440(-) m6A CDS       24284625//24209618 chr11:117160462-117160463(-) m6A CDS       24284625 chr11:117160471-117160472(-) m6A CDS       24284625 chr11:117164678-117164679(-) m6A 5'UTR//CDS//exon//intron       27773535 chr11:117164751-117164752(-) m6A exon//intron       27773535 chr11:117170375-117170376(-) m6A 5'UTR//intron       24284625 chr11:117170388-117170389(-) m6A 5'UTR//intron       24284625 chr11:117186317-117186318(-) m6A CDS//exon       24284625//25456834//24981863//27773536 chr11:117186372-117186373(-) m6A CDS//exon       24284625//25456834//24981863//27773536 chr11:117186581-117186582(-) m6A 5'UTR       24284625//25456834//24981863//27371828//27773536//22575960//22608085 chr11:117186668-117186669(-) m6A 5'UTR       24284625//25456834//24981863//27773536//22575960//22608085 chr11:117186839-117186840(-) m6A 5'UTR       24209618//24981863//27773536

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-29b-1-5p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Seminal plasma     23539611 Microvesicle Fibroblasts|Mesenchymal stem cells     - Mitochondrion Skeletal muscle myoblasts     21637849
	BACE1	Chromatin K562 cells     - Exosome Blood     - Nucleolus K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-29b-1-5p
Interactor2: BACE1

Evidence Support:

Weak-Evidence	RNA-Seq
Prediction-Evidence	miRecords
Support Database	ViRBase

References:

PMID	31570108	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	ARPE-19 human RPE cells	Interactor2 expression	None
Description	Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Additional file 6. List of validated miRNA targets from miRecords and miRTarBase databases.