Detail Information

Basic Information:


  VIRBase ID:  

HHID00009463

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-101-5p:           MRPS25:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-101-5p MRPS25
miRBase
Accession/Entrez ID		 MIMAT0004513 64432
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - COXPD50//MRP-S25//RPMS25

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-101-5p
rs1200170859 chr1:65058478    G/C
rs548109012 chr1:65058477    A/G
rs548109012 chr1:65058477    A/T
rs1235943983 chr1:65058493    T/C
rs746487797 chr1:65058492    A/G
rs777575128 chr1:65058491    G/C
rs777575128 chr1:65058491    G/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR MRPS25
chr3:15101895(-) A-I      intronic
chr3:15097527(-) A-I      intronic
chr3:15095997(-) A-I      intronic
chr3:15095550(-) A-I      intronic
chr3:15095582(-) A-I      intronic
chr3:15095594(-) A-I      intronic
chr3:15091330(-) A-I      3'UTR
chr3:15097665(-) A-I      intronic
chr3:15097635(-) A-I      intronic
chr3:15097610(-) A-I      intronic
chr3:15097622(-) A-I      intronic
chr3:15097653(-) A-I      intronic
chr3:15102266(-) A-I      intronic
chr3:15102263(-) A-I      intronic
chr3:15102241(-) A-I      intronic
chr3:15102240(-) A-I      intronic
chr3:15101920(-) A-I      intronic
chr3:15099991(-) A-I      intronic
chr3:15099794(-) A-I      intronic
chr3:15099786(-) A-I      intronic
chr3:15099444(-) A-I      intronic
chr3:15097556(-) A-I      intronic
chr3:15095661(-) A-I      intronic
chr3:15099500(-) A-I      intronic
chr3:15095711(-) A-I      intronic
chr3:15099610(-) A-I      intronic
chr3:15099968(-) A-I      intronic
chr3:15099655(-) A-I      intronic
chr3:15097476(-) A-I      intronic
chr3:15095507(-) A-I      intronic
chr3:15099586(-) A-I      intronic
chr3:15099517(-) A-I      intronic
chr3:15099925(-) A-I      intronic
chr3:15091322(-) A-I      3'UTR
chr3:15092962(-) A-I      3'UTR
chr3:15092829(-) A-I      3'UTR
chr3:15099537(-) A-I      intronic
chr3:15095519(-) A-I      intronic
chr3:15099459(-) A-I      intronic
chr3:15099579(-) A-I      intronic
chr3:15097458(-) A-I      intronic
chr3:15095529(-) A-I      intronic
chr3:15101817(-) A-I      intronic
chr3:15099891(-) A-I      intronic
chr3:15099726(-) A-I      intronic
chr3:15095704(-) A-I      intronic
chr3:15096005(-) A-I      intronic
chr3:15097572(-) A-I      intronic
chr3:15097464(-) A-I      intronic
chr3:15099662(-) A-I      intronic
chr3:15099933(-) A-I      intronic
chr3:15099880(-) A-I      intronic
chr3:15099460(-) A-I      intronic
chr3:15099952(-) A-I      intronic
chr3:15096008(-) A-I      intronic
chr3:15099727(-) A-I      intronic
chr3:15097531(-) A-I      intronic
chr3:15095498(-) A-I      intronic
chr3:15101763(-) A-I      intronic
chr3:15101835(-) A-I      intronic
chr3:15096018(-) A-I      intronic
chr3:15099535(-) A-I      intronic
chr3:15099877(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED MRPS25
chr3:15099662(-) A-I intron -    22327324
chr3:15092866(-) G-A exon 3'UTR    22484847
chr3:15095545(-) A-G intron -    22484847
chr3:15095599(-) A-G intron -    22484847
chr3:15096008(-) A-G intron -    22484847
chr3:15096018(-) A-G intron -    22484847
chr3:15099477(-) A-G intron -    22484847
chr3:15099489(-) A-G intron -    22484847
chr3:15099615(-) A-G intron -    22484847
chr3:15099662(-) A-G intron -    22484847
chr3:15099877(-) A-G intron -    22484847
chr3:15099880(-) A-G intron -    22484847
chr3:15099891(-) A-G intron -    22484847
chr3:15099933(-) A-G intron -    22484847
chr3:15101817(-) A-G intron -    22484847
chr3:15101835(-) A-G intron -    22484847
chr3:15102200(-) A-G intron -    22484847
chr3:15102208(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase MRPS25
chr3:15083985-15083986(-) m6A exon       24284625//24981863//27773535//22608085
chr3:15084010-15084011(-) m6A exon       24284625//24981863//27773535//22608085
chr3:15084020-15084021(-) m6A exon       24284625//24981863//27773535//22608085
chr3:15084051-15084052(-) m6A exon       24284625//24981863//27773535//22608085
chr3:15084074-15084075(-) m6A exon       24284625//24209618//24981863//27773535//22608085
chr3:15084160-15084161(-) m6A exon       24284625//24981863//27773535//22608085
chr3:15084239-15084240(-) m6A exon       24284625//24209618//24981863//27773535//22608085
chr3:15084309-15084310(-) m6A exon       24284625//24209618//24981863//27773535//22608085
chr3:15084418-15084419(-) m6A exon       24284625//24209618//24981863//27773535//22575960//22608085
chr3:15084432-15084433(-) m6A exon       24284625//24209618//24981863//27773535//22575960//22608085
chr3:15084508-15084509(-) m6A exon       24284625//24209618//24981863//27773535//22608085
chr3:15086619-15086620(-) m6A exon//intron       24284625//24209618//24981863//27773535//22608085
chr3:15086746-15086747(-) m6A exon//intron       24284625//27773535//27371828//22608085
chr3:15090031-15090032(-) m6A 3'UTR//intron       24284625//27773535//27371828//22608085
chr3:15090070-15090071(-) m6A 3'UTR//intron       24284625//27773535//22608085
chr3:15090219-15090220(-) m6A 3'UTR//intron       24284625//24981863//26404942//27773535
chr3:15090227-15090228(-) m6A 3'UTR//intron       24284625//24981863//26404942//27773535
chr3:15090254-15090255(-) m6A 3'UTR//intron       24284625//24981863//26404942//27773535
chr3:15090263-15090264(-) m6A 3'UTR//intron       24284625//24981863//26404942//27773535
chr3:15090308-15090309(-) m6A 3'UTR//intron       24284625//27773535
chr3:15090321-15090322(-) m6A 3'UTR//intron       24284625//27773535
chr3:15090458-15090459(-) m6A 3'UTR//intron       27773535
chr3:15090484-15090485(-) m6A 3'UTR//intron       27773535
chr3:15090545-15090546(-) m6A 3'UTR//intron       27773535
chr3:15090575-15090576(-) m6A 3'UTR//intron       27773535
chr3:15090609-15090610(-) m6A 3'UTR//intron       27773535
chr3:15090616-15090617(-) m6A 3'UTR//intron       27773535
chr3:15090643-15090644(-) m6A 3'UTR//intron       27773535
chr3:15090700-15090701(-) m6A 3'UTR//intron       27773535
chr3:15090749-15090750(-) m6A 3'UTR//intron       27773535
chr3:15090880-15090881(-) m6A 3'UTR//intron       24284625//24209618//27773535//22608085
chr3:15090885-15090886(-) m6A 3'UTR//intron       24284625//24209618//27773535//22608085
chr3:15090948-15090949(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr3:15090995-15090996(-) m6A 3'UTR//intron       24284625//24981863//22608085
chr3:15091055-15091056(-) m6A 3'UTR//intron       24284625//24981863//22608085
chr3:15091116-15091117(-) Y 3'UTR//intron       26075521
chr3:15091177-15091178(-) m6A 3'UTR//intron       24284625//25456834//24981863//27773535//27371828//22608085
chr3:15091222-15091223(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr3:15091243-15091244(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr3:15091250-15091251(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr3:15091417-15091418(-) m6A 3'UTR//CDS//exon       24284625//25456834//24981863//22608085
chr3:15092552-15092553(-) m6A 3'UTR//intron       24284625//22608085
chr3:15092575-15092576(-) m6A 3'UTR//intron       24284625//22608085
chr3:15092609-15092610(-) m6A 3'UTR//intron       24284625//22608085
chr3:15092626-15092627(-) m6A 3'UTR//intron       24284625//22608085
chr3:15092640-15092641(-) m6A 3'UTR//intron       24284625//22608085
chr3:15092650-15092651(-) m6A 3'UTR//intron       24284625//22608085
chr3:15092657-15092658(-) m6A 3'UTR//intron       24284625//22608085
chr3:15092666-15092667(-) m6A 3'UTR//intron       24284625//22608085
chr3:15092717-15092718(-) m6A 3'UTR//intron       24284625//22608085
chr3:15093817-15093818(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr3:15093845-15093846(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr3:15093951-15093952(-) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr3:15094135-15094136(-) m6A 3'UTR//CDS//intron       24284625//24209618//24981863//27773535
chr3:15094857-15094858(-) m6A 3'UTR//intron       24284625//24209618//24981863//27773535
chr3:15094926-15094927(-) Gm CDS//intron       -
chr3:15094941-15094942(-) m6A CDS//intron       24209618//24981863//27773535
chr3:15100910-15100911(-) m6A CDS       24209618//24981863//27773535
chr3:15100940-15100941(-) m6A CDS       27773535
chr3:15106627-15106628(-) m6A CDS       22575960
chr3:15106658-15106659(-) Y CDS       26075521
chr3:15106809-15106810(-) m6A 5'UTR       24284625//24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-101-5p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cerebrospinal fluid     24797360
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
MRPS25
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -
Ribosome Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-101-5p
Benzothiazole 7222 Drug interaction    RC00006831
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-101-5p
Methyl (9R,10S,11S,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15R,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate 134755071       26617885

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-101-5p
Interactor2: MRPS25

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

Starting a new search, please wait ...