Detail Information

Basic Information:


  VIRBase ID:  

HHID00009285

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-101-5p:           SNX13:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-101-5p SNX13
miRBase
Accession/Entrez ID		 MIMAT0004513 23161
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - RGS-PX1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-101-5p
rs1200170859 chr1:65058478    G/C
rs548109012 chr1:65058477    A/G
rs548109012 chr1:65058477    A/T
rs1235943983 chr1:65058493    T/C
rs746487797 chr1:65058492    A/G
rs777575128 chr1:65058491    G/C
rs777575128 chr1:65058491    G/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SNX13
chr7:17855156(-) A-I      intronic
chr7:17966476(-) A-I      intronic
chr7:17967084(-) A-I      intronic
chr7:17966291(-) A-I      intronic
chr7:17966365(-) A-I      intronic
chr7:17952209(-) A-I      intronic
chr7:17964588(-) A-I      intronic
chr7:17966307(-) A-I      intronic
chr7:17966341(-) A-I      intronic
chr7:17855199(-) A-I      intronic
chr7:17966990(-) A-I      intronic
chr7:17966468(-) A-I      intronic
chr7:17876962(-) A-I      intronic
chr7:17951179(-) A-I      intronic
chr7:17966433(-) A-I      intronic
chr7:17951180(-) A-I      intronic
chr7:17967139(-) A-I      intronic
chr7:17966981(-) A-I      intronic
chr7:17952211(-) A-I      intronic
chr7:17967952(-) A-I      intronic
chr7:17916036(-) A-I      intronic
chr7:17859038(-) A-I      intronic
chr7:17967026(-) A-I      intronic
chr7:17952210(-) A-I      intronic
chr7:17964761(-) A-I      intronic
chr7:17966987(-) A-I      intronic
chr7:17918939(-) A-I      intronic
chr7:17856176(-) A-I      intronic
chr7:17952136(-) A-I      intronic
chr7:17951140(-) A-I      intronic
chr7:17859123(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED SNX13
chr7:17951140(-) A-G intron -    22484847
chr7:17951179(-) A-G intron -    22484847
chr7:17951180(-) A-G intron -    22484847
chr7:17952307(-) A-G intron -    22484847
chr7:17964754(-) A-G intron -    22484847
chr7:17964823(-) A-G intron -    22484847
chr7:17966298(-) A-G intron -    22484847
chr7:17966387(-) A-G intron -    22484847
chr7:17966433(-) A-G intron -    22484847
chr7:17966468(-) A-G intron -    22484847
chr7:17966987(-) A-G intron -    22484847
chr7:17966990(-) A-G intron -    22484847
chr7:17967026(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SNX13
chr7:17830386-17830387(-) m6A 3'UTR       27773535
chr7:17830488-17830489(-) m6A 3'UTR       27773535
chr7:17832508-17832509(-) m6A 3'UTR       27773535
chr7:17832530-17832531(-) m6A 3'UTR       27773535
chr7:17832609-17832610(-) m6A 3'UTR       27773535
chr7:17833050-17833051(-) m6A 3'UTR       27773535
chr7:17833059-17833060(-) m6A 3'UTR       27773535
chr7:17833141-17833142(-) m6A 3'UTR       27773535
chr7:17833168-17833169(-) m6A 3'UTR       27773535
chr7:17833271-17833272(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085
chr7:17833316-17833317(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085
chr7:17833384-17833385(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085
chr7:17833431-17833432(-) m6A 3'UTR//exon       24284625//24209618//24981863//27773535//22608085
chr7:17833616-17833617(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//22575960//22608085
chr7:17833629-17833630(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//22575960//22608085
chr7:17833700-17833701(-) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr7:17833707-17833708(-) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr7:17833713-17833714(-) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//27773535//22575960//22608085
chr7:17833749-17833750(-) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//27773535//22575960//22608085
chr7:17833761-17833762(-) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//27773535//22575960//22608085
chr7:17833790-17833791(-) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//27773535//22575960//22608085
chr7:17833886-17833887(-) m6A 3'UTR//CDS//exon       24284625//24981863//27773535//22608085
chr7:17833982-17833983(-) m6A 3'UTR//intron       27773535
chr7:17938980-17938981(-) m6A exon//intron       27773535
chr7:17939161-17939162(-) m6A exon//intron       27773535
chr7:17939169-17939170(-) m6A exon//intron       27773535
chr7:17980028-17980029(-) m6A 5'UTR//exon       24981863
chr7:17980046-17980047(-) m6A 5'UTR//exon       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-101-5p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cerebrospinal fluid     24797360
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
SNX13
Chromatin K562 cells     -
Cytosol HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Insoluble cytoplasm K562 cells     -
Membrane HCC cell line (HepG2)|K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|K562 cells     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-101-5p
Benzothiazole 7222 Drug interaction    RC00006831
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-101-5p
Methyl (9R,10S,11S,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15R,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate 134755071       26617885

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-101-5p
Interactor2: SNX13

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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