Detail Information

Basic Information:


  VIRBase ID:  

HHID00008412

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-100-3p:           FAM169A:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-100-3p FAM169A
miRBase
Accession/Entrez ID		 MIMAT0004512 26049
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - SLAP75

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-100-3p
rs1388368183 chr11:122152253    A/G
rs530428149 chr11:122152245    C/T
rs749039221 chr11:122152247    A/G
rs775253529 chr11:122152245    CTA/C
rs909526986 chr11:122152248    T/C
rs1321972926 chr11:122152258    C/T
rs770590792 chr11:122152255    A/G
rs773933142 chr11:122152260    T/C
rs773933142 chr11:122152260    T/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR FAM169A
chr5:74141221(-) A-I      intronic
chr5:74141305(-) A-I      intronic
chr5:74142662(-) A-I      intronic
chr5:74142663(-) A-I      intronic
chr5:74142672(-) A-I      intronic
chr5:74150002(-) A-I      intronic
chr5:74150008(-) A-I      intronic
chr5:74155394(-) A-I      intronic
chr5:74157150(-) A-I      intronic
chr5:74105312(-) A-I      intronic
chr5:74105230(-) A-I      intronic
chr5:74154096(-) A-I      intronic
chr5:74133830(-) A-I      intronic
chr5:74154037(-) A-I      intronic
chr5:74150138(-) A-I      intronic
chr5:74150144(-) A-I      intronic
chr5:74150151(-) A-I      intronic
chr5:74151196(-) A-I      intronic
chr5:74156506(-) A-I      intronic
chr5:74154104(-) A-I      intronic
chr5:74154987(-) A-I      intronic
chr5:74151203(-) A-I      intronic
chr5:74155243(-) A-I      intronic
chr5:74155247(-) A-I      intronic
chr5:74155275(-) A-I      intronic
chr5:74155293(-) A-I      intronic
chr5:74156525(-) A-I      intronic
chr5:74151215(-) A-I      intronic
chr5:74155364(-) A-I      intronic
chr5:74155322(-) A-I      intronic
chr5:74155316(-) A-I      intronic
chr5:74155308(-) A-I      intronic
chr5:74109214(-) A-I      intronic
chr5:74108054(-) A-I      intronic
chr5:74108041(-) A-I      intronic
chr5:74107013(-) A-I      intronic
chr5:74155294(-) A-I      intronic
chr5:74152687(-) A-I      intronic
chr5:74152690(-) A-I      intronic
chr5:74152692(-) A-I      intronic
chr5:74152815(-) A-I      intronic
chr5:74154006(-) A-I      intronic
chr5:74154069(-) A-I      intronic
chr5:74154081(-) A-I      intronic
chr5:74154085(-) A-I      intronic
chr5:74109257(-) A-I      intronic
chr5:74154199(-) A-I      intronic
chr5:74109219(-) A-I      intronic
chr5:74154211(-) A-I      intronic
chr5:74154847(-) A-I      intronic
chr5:74154089(-) A-I      intronic
chr5:74106512(-) A-I      intronic
chr5:74106475(-) A-I      intronic
chr5:74106453(-) A-I      intronic
chr5:74106407(-) A-I      intronic
chr5:74106349(-) A-I      intronic
chr5:74105364(-) A-I      intronic
chr5:74154922(-) A-I      intronic
chr5:74156535(-) A-I      intronic
chr5:74154953(-) A-I      intronic
chr5:74148537(-) A-I      intronic
chr5:74125676(-) A-I      intronic
chr5:74105176(-) A-I      intronic
chr5:74111256(-) A-I      intronic
chr5:74111258(-) A-I      intronic
chr5:74123709(-) A-I      intronic
chr5:74133760(-) A-I      intronic
chr5:74114862(-) A-I      intronic
chr5:74156497(-) A-I      intronic
chr5:74157103(-) A-I      intronic
chr5:74157104(-) A-I      intronic
chr5:74157122(-) A-I      intronic
chr5:74157146(-) A-I      intronic
chr5:74154175(-) A-I      intronic
chr5:74105334(-) A-I      intronic
chr5:74137994(-) A-I      intronic
chr5:74138208(-) A-I      intronic
chr5:74141122(-) A-I      intronic
chr5:74090644(-) A-I      intronic
chr5:74101448(-) A-I      intronic
chr5:74109220(-) A-I      intronic
chr5:74106947(-) A-I      intronic
chr5:74155030(-) A-I      intronic
chr5:74151296(-) A-I      intronic
chr5:74133708(-) A-I      intronic
chr5:74160194(-) A-I      intronic
chr5:74133725(-) A-I      intronic
chr5:74154952(-) A-I      intronic
chr5:74105299(-) A-I      intronic
chr5:74138184(-) A-I      intronic
chr5:74154008(-) A-I      intronic
chr5:74106332(-) A-I      intronic
chr5:74151205(-) A-I      intronic
chr5:74149681(-) A-I      intronic
chr5:74154101(-) A-I      intronic
chr5:74151200(-) A-I      intronic
chr5:74154045(-) A-I      intronic
chr5:74155380(-) A-I      intronic
chr5:74151250(-) A-I      intronic
chr5:74106946(-) A-I      intronic
chr5:74114881(-) A-I      intronic
chr5:74141179(-) A-I      intronic
chr5:74154113(-) A-I      intronic
chr5:74154782(-) A-I      intronic
chr5:74155385(-) A-I      intronic
chr5:74154841(-) A-I      intronic
chr5:74154127(-) A-I      intronic
chr5:74107012(-) A-I      intronic
chr5:74154872(-) A-I      intronic
chr5:74149665(-) A-I      intronic
chr5:74106410(-) A-I      intronic
chr5:74157464(-) A-I      intronic
chr5:74150137(-) A-I      intronic
chr5:74138232(-) A-I      intronic
chr5:74106876(-) A-I      intronic
chr5:74154927(-) A-I      intronic
chr5:74155363(-) A-I      intronic
chr5:74106385(-) A-I      intronic
chr5:74138435(-) A-I      intronic
chr5:74154870(-) A-I      intronic
chr5:74151113(-) A-I      intronic
chr5:74109354(-) A-I      intronic
chr5:74154105(-) A-I      intronic
chr5:74154131(-) A-I      intronic
chr5:74160274(-) A-I      intronic
chr5:74109355(-) A-I      intronic
chr5:74123560(-) A-I      intronic
chr5:74108087(-) A-I      intronic
chr5:74138465(-) A-I      intronic
chr5:74149661(-) A-I      intronic
chr5:74154795(-) A-I      intronic
chr5:74154875(-) A-I      intronic
chr5:74154137(-) A-I      intronic
chr5:74155252(-) A-I      intronic
chr5:74154957(-) A-I      intronic
chr5:74138512(-) A-I      intronic
chr5:74106988(-) A-I      intronic
chr5:74114896(-) A-I      intronic
chr5:74150098(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED FAM169A
chr5:74095237(-) A-I intron -    22327324
chr5:74156448(-) A-G intron -    22484847
chr5:74156468(-) A-G intron -    22484847
chr5:74156475(-) A-G intron -    22484847
chr5:74157116(-) A-G intron -    22484847
chr5:74105299(-) A-G intron -    22484847
chr5:74106331(-) A-G intron -    22484847
chr5:74106332(-) A-G intron -    22484847
chr5:74106385(-) A-G intron -    22484847
chr5:74106410(-) A-G intron -    22484847
chr5:74107012(-) A-G intron -    22484847
chr5:74109354(-) A-G intron -    22484847
chr5:74109355(-) A-G intron -    22484847
chr5:74133708(-) A-G intron -    22484847
chr5:74133725(-) A-G intron -    22484847
chr5:74133840(-) T-C intron -    22484847
chr5:74138183(-) A-G intron -    22484847
chr5:74138184(-) A-G intron -    22484847
chr5:74138232(-) A-G intron -    22484847
chr5:74138435(-) A-G intron -    22484847
chr5:74138465(-) A-G intron -    22484847
chr5:74138512(-) A-G intron -    22484847
chr5:74141154(-) A-G intron -    22484847
chr5:74141179(-) A-G intron -    22484847
chr5:74141231(-) A-G intron -    22484847
chr5:74149661(-) A-G intron -    22484847
chr5:74149665(-) A-G intron -    22484847
chr5:74149671(-) A-G intron -    22484847
chr5:74149681(-) A-G intron -    22484847
chr5:74149697(-) A-G intron -    22484847
chr5:74150103(-) A-G intron -    22484847
chr5:74150108(-) A-G intron -    22484847
chr5:74150137(-) A-G intron -    22484847
chr5:74151113(-) A-G intron -    22484847
chr5:74151200(-) A-G intron -    22484847
chr5:74151202(-) A-G intron -    22484847
chr5:74151205(-) A-G intron -    22484847
chr5:74151250(-) A-G intron -    22484847
chr5:74151298(-) A-G intron -    22484847
chr5:74153956(-) A-G intron -    22484847
chr5:74154008(-) A-G intron -    22484847
chr5:74154045(-) A-G intron -    22484847
chr5:74154101(-) A-G intron -    22484847
chr5:74154105(-) A-G intron -    22484847
chr5:74154113(-) A-G intron -    22484847
chr5:74154126(-) A-G intron -    22484847
chr5:74154130(-) A-G intron -    22484847
chr5:74154131(-) A-G intron -    22484847
chr5:74154137(-) A-G intron -    22484847
chr5:74154191(-) A-G intron -    22484847
chr5:74154782(-) A-G intron -    22484847
chr5:74154795(-) A-G intron -    22484847
chr5:74154872(-) A-G intron -    22484847
chr5:74154875(-) A-G intron -    22484847
chr5:74154883(-) A-G intron -    22484847
chr5:74154891(-) A-G intron -    22484847
chr5:74154917(-) A-G intron -    22484847
chr5:74154927(-) A-G intron -    22484847
chr5:74154952(-) A-G intron -    22484847
chr5:74154957(-) A-G intron -    22484847
chr5:74155252(-) A-G intron -    22484847
chr5:74155253(-) A-G intron -    22484847
chr5:74155363(-) A-G intron -    22484847
chr5:74155380(-) A-G intron -    22484847
chr5:74155385(-) A-G intron -    22484847
chr5:74157464(-) A-G intron -    22484847
chr5:74160194(-) A-G intron -    22484847
chr5:74160274(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase FAM169A
chr5:74077165-74077166(-) m6A 3'UTR       24981863//27773535//22608085
chr5:74077192-74077193(-) m6A 3'UTR       24981863//27773535//22608085
chr5:74077209-74077210(-) m6A 3'UTR       24284625//24981863//27773535//22608085
chr5:74077314-74077315(-) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//22608085
chr5:74077354-74077355(-) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr5:74077479-74077480(-) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr5:74077512-74077513(-) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr5:74077553-74077554(-) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr5:74077588-74077589(-) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22608085
chr5:74077635-74077636(-) m6A 3'UTR//CDS       24284625//25456834//24981863//26404942//27773535//27371828//22608085
chr5:74077663-74077664(-) m6A 3'UTR//CDS       24284625//25456834//24981863//26404942//27773535//27371828//22608085
chr5:74077714-74077715(-) m6A 3'UTR//CDS       24284625//25456834//24981863//27773535//27371828//22608085
chr5:74078782-74078783(-) m6A 3'UTR//CDS       27773535
chr5:74078822-74078823(-) m6A 3'UTR//CDS       27773535
chr5:74078882-74078883(-) m6A 3'UTR//CDS       24981863//27773535
chr5:74078907-74078908(-) m6A 3'UTR//CDS       24981863//27773535
chr5:74091889-74091890(-) m6A 3'UTR//CDS       24981863//27773535
chr5:74091950-74091951(-) m6A 3'UTR//CDS       24981863//27773535
chr5:74091956-74091957(-) m6A 3'UTR//CDS       24981863//27773535
chr5:74096707-74096708(-) m6A 3'UTR//CDS       24981863//27773535
chr5:74096729-74096730(-) m6A 3'UTR//CDS       27773535
chr5:74096738-74096739(-) m6A 3'UTR//CDS       27773535
chr5:74130362-74130363(-) m6A CDS//intron       24981863
chr5:74134821-74134822(-) m6A CDS       24981863
chr5:74162089-74162090(-) m6A 5'UTR//intron       27773536
chr5:74162590-74162591(-) m6A 5'UTR//intron       27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-100-3p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
FAM169A
Cytosol HCC cell line (HepG2)     -
Exosome Blood     -
Nucleus HCC cell line (HepG2)     -
Ribosome Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-100-3p
Methyl (9R,10S,11S,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15R,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate 134755071       26617885

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-100-3p
Interactor2: FAM169A

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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