Basic Information:

  VIRBase ID:  

HHID00008350

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-100-3p:  MIMAT0004512          CEP43:  NM_194429     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-100-3p	CEP43
miRBase Accession/Entrez ID	MIMAT0004512	11116
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	FGFR1OP//FOP

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-100-3p	rs1388368183 chr11:122152253    A/G rs530428149 chr11:122152245    C/T rs749039221 chr11:122152247    A/G rs775253529 chr11:122152245    CTA/C rs909526986 chr11:122152248    T/C rs1321972926 chr11:122152258    C/T rs770590792 chr11:122152255    A/G rs773933142 chr11:122152260    T/C rs773933142 chr11:122152260    T/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	CEP43	chr6:167423098(+) A-I      intronic chr6:167423055(+) A-I      intronic chr6:167423103(+) A-I      intronic chr6:167422948(+) A-I      intronic chr6:167432044(+) A-I      intronic chr6:167422624(+) A-I      intronic chr6:167427310(+) A-I      intronic chr6:167422851(+) A-I      intronic chr6:167427276(+) A-I      intronic chr6:167422493(+) A-I      intronic chr6:167422224(+) A-I      intronic chr6:167422113(+) A-I      intronic chr6:167419970(+) A-I      intronic chr6:167452735(+) A-I      intronic chr6:167446765(+) A-I      intronic chr6:167423226(+) A-I      intronic chr6:167446764(+) A-I      intronic chr6:167434290(+) A-I      intronic chr6:167434236(+) A-I      intronic chr6:167432088(+) A-I      intronic chr6:167423203(+) A-I      intronic chr6:167427413(+) A-I      intronic chr6:167423105(+) A-I      intronic chr6:167422487(+) A-I      intronic chr6:167434275(+) A-I      intronic chr6:167432005(+) A-I      intronic chr6:167427300(+) A-I      intronic chr6:167422162(+) A-I      intronic chr6:167434517(+) A-I      intronic chr6:167434385(+) A-I      intronic chr6:167427301(+) A-I      intronic chr6:167431978(+) A-I      intronic chr6:167419950(+) A-I      intronic chr6:167434325(+) A-I      intronic chr6:167423060(+) A-I      intronic chr6:167449329(+) A-I      intronic chr6:167422145(+) A-I      intronic chr6:167423166(+) A-I      intronic chr6:167422465(+) A-I      intronic chr6:167422625(+) A-I      intronic chr6:167422150(+) A-I      intronic chr6:167430690(+) A-I      intronic chr6:167422848(+) A-I      intronic chr6:167434293(+) A-I      intronic chr6:167422900(+) A-I      intronic chr6:167422008(+) A-I      intronic chr6:167434241(+) A-I      intronic chr6:167434470(+) A-I      intronic chr6:167434573(+) A-I      intronic chr6:167432064(+) A-I      intronic chr6:167452770(+) A-I      intronic chr6:167434238(+) A-I      intronic chr6:167419816(+) A-I      intronic chr6:167434276(+) A-I      intronic chr6:167422236(+) A-I      intronic chr6:167427346(+) A-I      intronic chr6:167429874(+) A-I      intronic chr6:167430744(+) A-I      intronic chr6:167422859(+) A-I      intronic chr6:167429882(+) A-I      intronic chr6:167434347(+) A-I      intronic chr6:167427207(+) A-I      intronic chr6:167432062(+) A-I      intronic chr6:167422943(+) A-I      intronic chr6:167419965(+) A-I      intronic chr6:167434235(+) A-I      intronic chr6:167422904(+) A-I      intronic chr6:167422073(+) A-I      intronic chr6:167455509(+) A-I      3'UTR chr6:167455557(+) A-I      3'UTR chr6:167455512(+) A-I      3'UTR chr6:167455429(+) A-I      3'UTR chr6:167455365(+) A-I      3'UTR chr6:167430601(+) A-I      intronic chr6:167427308(+) A-I      intronic chr6:167434317(+) A-I      intronic chr6:167434357(+) A-I      intronic chr6:167430623(+) A-I      intronic chr6:167419888(+) A-I      intronic chr6:167427314(+) A-I      intronic chr6:167432008(+) A-I      intronic chr6:167419925(+) A-I      intronic chr6:167430665(+) A-I      intronic chr6:167422694(+) A-I      intronic chr6:167423201(+) A-I      intronic chr6:167434306(+) A-I      intronic chr6:167434282(+) A-I      intronic chr6:167434190(+) A-I      intronic chr6:167422022(+) A-I      intronic chr6:167432079(+) A-I      intronic chr6:167429931(+) A-I      intronic chr6:167422887(+) A-I      intronic chr6:167427341(+) A-I      intronic chr6:167434239(+) A-I      intronic chr6:167422085(+) A-I      intronic chr6:167429791(+) A-I      intronic chr6:167434133(+) A-I      intronic chr6:167434211(+) A-I      intronic chr6:167434277(+) A-I      intronic chr6:167427309(+) A-I      intronic chr6:167422015(+) A-I      intronic chr6:167434141(+) A-I      intronic chr6:167423341(+) A-I      intronic chr6:167422095(+) A-I      intronic chr6:167422223(+) A-I      intronic chr6:167434210(+) A-I      intronic chr6:167434309(+) A-I      intronic chr6:167431979(+) A-I      intronic chr6:167430743(+) A-I      intronic chr6:167429985(+) A-I      intronic chr6:167434574(+) A-I      intronic chr6:167422799(+) A-I      intronic chr6:167427350(+) A-I      intronic chr6:167422820(+) A-I      intronic chr6:167434566(+) A-I      intronic chr6:167430548(+) A-I      intronic chr6:167434213(+) A-I      intronic chr6:167429879(+) A-I      intronic chr6:167423204(+) A-I      intronic chr6:167422205(+) A-I      intronic chr6:167422587(+) A-I      intronic chr6:167429772(+) A-I      intronic chr6:167423102(+) A-I      intronic chr6:167423124(+) A-I      intronic chr6:167434245(+) A-I      intronic chr6:167422822(+) A-I      intronic chr6:167434219(+) A-I      intronic chr6:167419892(+) A-I      intronic chr6:167430011(+) A-I      intronic chr6:167430024(+) A-I      intronic chr6:167422097(+) A-I      intronic chr6:167434379(+) A-I      intronic chr6:167434220(+) A-I      intronic chr6:167434221(+) A-I      intronic chr6:167432139(+) A-I      intronic chr6:167434237(+) A-I      intronic chr6:167434142(+) A-I      intronic chr6:167430564(+) A-I      intronic chr6:167434303(+) A-I      intronic chr6:167422877(+) A-I      intronic chr6:167422488(+) A-I      intronic

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-100-3p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     -
	CEP43	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus K562 cells     - Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	PMID
NoncoRNA	hsa-miR-100-3p	Methyl (9R,10S,11S,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15R,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate 134755071       26617885

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-100-3p
Interactor2: CEP43

Evidence Support:

Weak-Evidence	RNA-Seq
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	31570108	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	ARPE-19 human RPE cells	Interactor2 expression	None
Description	Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).