Detail Information

Basic Information:


  VIRBase ID:  

HHID00007948

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-100-3p:           ACADL:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-100-3p ACADL
miRBase
Accession/Entrez ID		 MIMAT0004512 33
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - ACAD4//LCAD

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-100-3p
rs1388368183 chr11:122152253    A/G
rs530428149 chr11:122152245    C/T
rs749039221 chr11:122152247    A/G
rs775253529 chr11:122152245    CTA/C
rs909526986 chr11:122152248    T/C
rs1321972926 chr11:122152258    C/T
rs770590792 chr11:122152255    A/G
rs773933142 chr11:122152260    T/C
rs773933142 chr11:122152260    T/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR ACADL
chr2:211086610(-) A-I      intronic
chr2:211086709(-) A-I      intronic
chr2:211071102(-) A-I      intronic
chr2:211071103(-) A-I      intronic
chr2:211071175(-) A-I      intronic
chr2:211076784(-) A-I      intronic
chr2:211086561(-) A-I      intronic
chr2:211088864(-) A-I      intronic
chr2:211086562(-) A-I      intronic
chr2:211086564(-) A-I      intronic
chr2:211071570(-) A-I      intronic
chr2:211088863(-) A-I      intronic
chr2:211088859(-) A-I      intronic
chr2:211088813(-) A-I      intronic
chr2:211088788(-) A-I      intronic
chr2:211088785(-) A-I      intronic
chr2:211086726(-) A-I      intronic
chr2:211086590(-) A-I      intronic
chr2:211071576(-) A-I      intronic
chr2:211071580(-) A-I      intronic
chr2:211071583(-) A-I      intronic
chr2:211076776(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ACADL
chr2:211053004-211053005(-) m6A 3'UTR       22608085
chr2:211053073-211053074(-) m6A 3'UTR       22608085
chr2:211053082-211053083(-) m6A 3'UTR       22608085
chr2:211053128-211053129(-) m6A 3'UTR       22608085
chr2:211053157-211053158(-) m6A 3'UTR       22608085
chr2:211053174-211053175(-) m6A 3'UTR       22608085
chr2:211053187-211053188(-) m6A 3'UTR       22608085
chr2:211089295-211089296(-) m6A exon//intron       22608085
chr2:211089355-211089356(-) m6A exon//intron       22608085
chr2:211089395-211089396(-) m6A exon//intron       22608085
chr2:211089411-211089412(-) m6A exon//intron       22608085
chr2:211089436-211089437(-) m6A exon//intron       22608085
chr2:211089442-211089443(-) m6A exon//intron       22608085
chr2:211089449-211089450(-) m6A exon//intron       22608085
chr2:211089468-211089469(-) m6A exon//intron       22608085
chr2:211089491-211089492(-) m6A exon//intron       22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-100-3p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
ACADL
Exosome Blood     -

Related Drug Information:


Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-100-3p
Methyl (9R,10S,11S,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15R,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate 134755071       26617885

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-100-3p
Interactor2: ACADL

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

Starting a new search, please wait ...