Detail Information

Basic Information:


  VIRBase ID:  

HHID00007946

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-100-3p:           TYMSOS:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-100-3p TYMSOS
miRBase
Accession/Entrez ID		 MIMAT0004512 494514
Organism Homo sapiens Homo sapiens
Category miRNA lncRNA
Alias - C18orf56

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-100-3p
rs1388368183 chr11:122152253    A/G
rs530428149 chr11:122152245    C/T
rs749039221 chr11:122152247    A/G
rs775253529 chr11:122152245    CTA/C
rs909526986 chr11:122152248    T/C
rs1321972926 chr11:122152258    C/T
rs770590792 chr11:122152255    A/G
rs773933142 chr11:122152260    T/C
rs773933142 chr11:122152260    T/G
Resource Symbol SNP ID SNP Position Ref/Alt PMID
LincSNP 3.0 TYMSOS
rs2853741 chr18:657352 T/C         17052657
rs11664283 chr18:650968 A/G         20339536
rs2853533 chr18:658064 C/G         20339536
rs7237052 chr18:642678 A/C         20502693
rs1058151 chr18:649759 A/G         20502693
rs9967368 chr18:656020 C/G         20502693
rs7237413 chr18:642876 C/T         20502693
rs11081234 chr18:650816 A/G         22233810
rs523230 chr18:653847 C/T         22233810
rs9966612 chr18:649311 A/G         23474282

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR TYMSOS
chr18:651808(-) A-I      intronic
chr18:651788(-) A-I      intronic
chr18:651833(-) A-I      intronic
chr18:651793(-) A-I      intronic
chr18:654309(-) A-I      intronic
chr18:656263(-) A-I      intronic
chr18:651786(-) A-I      intronic
chr18:656301(-) A-I      intronic
chr18:651785(-) A-I      intronic
chr18:651817(-) A-I      intronic
chr18:651775(-) A-I      intronic
chr18:651329(-) A-I      intronic
chr18:651795(-) A-I      intronic
chr18:651797(-) A-I      intronic
chr18:656121(-) A-I      intronic
chr18:656247(-) A-I      intronic
chr18:654312(-) A-I      intronic
chr18:654375(-) A-I      intronic
chr18:654388(-) A-I      intronic
chr18:654399(-) A-I      intronic
chr18:654423(-) A-I      intronic
chr18:656250(-) A-I      intronic
chr18:656222(-) A-I      intronic
chr18:656163(-) A-I      intronic
chr18:655244(-) A-I      intronic
chr18:657067(-) A-I      intronic
chr18:651725(-) A-I      intronic
chr18:651715(-) A-I      intronic
chr18:651248(-) A-I      intronic
chr18:651375(-) A-I      intronic
chr18:651791(-) A-I      intronic
chr18:656293(-) A-I      intronic
chr18:651814(-) A-I      intronic
chr18:656136(-) A-I      intronic
chr18:656207(-) A-I      intronic
chr18:656189(-) A-I      intronic
chr18:656094(-) A-I      intronic
chr18:655053(-) A-I      intronic
chr18:656226(-) A-I      intronic
chr18:654292(-) A-I      intronic
chr18:651770(-) A-I      intronic
chr18:657139(-) A-I      intronic
chr18:656149(-) A-I      intronic
chr18:654392(-) A-I      intronic
chr18:651328(-) A-I      intronic
chr18:654229(-) A-I      intronic
chr18:657099(-) A-I      intronic
chr18:654389(-) A-I      intronic
chr18:657047(-) A-I      intronic
chr18:651311(-) A-I      intronic
chr18:656117(-) A-I      intronic
chr18:657102(-) A-I      intronic
chr18:656140(-) A-I      intronic
chr18:654230(-) A-I      intronic
chr18:655264(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase TYMSOS
chr18:649624-649625(-) m6A exon//intron       27773535
chr18:649738-649739(-) m6A exon//intron       27773535//22608085
chr18:649841-649842(-) m6A exon//intron       22608085
chr18:658045-658046(-) m6A exon       27773536
chr18:658310-658311(-) m6A exon       24981863//27371828
chr18:658318-658319(-) m6A exon       24981863//27371828

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-100-3p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
TYMSOS
Exosome Blood     -
Nucleus HeLa-S3 cells     -

Related Drug Information:


Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-100-3p
Methyl (9R,10S,11S,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15R,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate 134755071       26617885

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-100-3p
Interactor2: TYMSOS

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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