Basic Information:

  VIRBase ID:  

HHID00007779

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-19b-1-5p:  MIMAT0004491          FAM155A:  NM_001080396     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-19b-1-5p	FAM155A
miRBase Accession/Entrez ID	MIMAT0004491	728215
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	NLF-1

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-19b-1-5p	rs1330845252 chr13:91351221    G/A rs771220050 chr13:91351229    C/T rs1259633726 chr13:91351212    T/G rs1279688822 chr13:91351213    G/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	FAM155A	chr13:108374743(-) A-I      intronic chr13:108374731(-) A-I      intronic chr13:108373579(-) A-I      intronic chr13:108107599(-) A-I      intronic chr13:108411762(-) A-I      intronic chr13:108367814(-) A-I      intronic chr13:108410960(-) A-I      intronic chr13:108410969(-) A-I      intronic chr13:108107593(-) A-I      intronic chr13:108411761(-) A-I      intronic chr13:108107583(-) A-I      intronic chr13:108107577(-) A-I      intronic chr13:108490705(-) A-I      intronic chr13:108490837(-) A-I      intronic chr13:108006817(-) A-I      intronic chr13:108006830(-) A-I      intronic chr13:108008002(-) A-I      intronic chr13:108106742(-) A-I      intronic chr13:108361209(-) A-I      intronic chr13:108490710(-) A-I      intronic chr13:108380838(-) A-I      intronic chr13:108507110(-) A-I      intronic chr13:108383955(-) A-I      intronic chr13:108384007(-) A-I      intronic chr13:108384012(-) A-I      intronic chr13:107962642(-) A-I      intronic chr13:108490887(-) A-I      intronic chr13:108335534(-) A-I      intronic chr13:108033765(-) A-I      intronic chr13:108508377(-) A-I      intronic chr13:108507189(-) A-I      intronic chr13:108507159(-) A-I      intronic chr13:108489463(-) A-I      intronic chr13:108489729(-) A-I      intronic chr13:108489571(-) A-I      intronic chr13:108379153(-) A-I      intronic chr13:108429340(-) A-I      intronic chr13:108507090(-) A-I      intronic chr13:108107592(-) A-I      intronic chr13:108122152(-) A-I      intronic chr13:108122230(-) A-I      intronic chr13:108156537(-) A-I      intronic chr13:108220542(-) A-I      intronic chr13:108231685(-) A-I      intronic chr13:108267293(-) A-I      intronic chr13:108267343(-) A-I      intronic chr13:108267362(-) A-I      intronic chr13:108355858(-) A-I      intronic chr13:108355866(-) A-I      intronic chr13:108355869(-) A-I      intronic chr13:108355870(-) A-I      intronic chr13:108355876(-) A-I      intronic chr13:108355879(-) A-I      intronic chr13:108377007(-) A-I      intronic chr13:108377109(-) A-I      intronic chr13:108411043(-) A-I      intronic chr13:108411725(-) A-I      intronic chr13:108411731(-) A-I      intronic chr13:108411740(-) A-I      intronic chr13:108411785(-) A-I      intronic chr13:108411790(-) A-I      intronic chr13:108433108(-) A-I      intronic chr13:108444256(-) A-I      intronic chr13:108449622(-) A-I      intronic chr13:108504303(-) A-I      intronic chr13:108511029(-) A-I      intronic chr13:107992733(-) A-I      intronic chr13:108507036(-) A-I      intronic chr13:107962540(-) A-I      intronic chr13:107992627(-) A-I      intronic chr13:108337546(-) A-I      intronic chr13:108514020(-) A-I      intronic chr13:108366893(-) A-I      intronic chr13:107992693(-) A-I      intronic chr13:107963122(-) A-I      intronic chr13:107963093(-) A-I      intronic chr13:108274446(-) A-I      intronic chr13:108090895(-) A-I      intronic chr13:108377911(-) A-I      intronic chr13:108508416(-) A-I      intronic chr13:107980508(-) A-I      intronic chr13:107992716(-) A-I      intronic chr13:108355862(-) A-I      intronic chr13:107991224(-) A-I      intronic chr13:108348482(-) A-I      intronic chr13:108438761(-) A-I      intronic chr13:108175090(-) A-I      intronic chr13:108424262(-) A-I      intronic chr13:108076704(-) A-I      intronic chr13:108124489(-) A-I      intronic chr13:108444272(-) A-I      intronic chr13:108372673(-) A-I      intronic chr13:108367551(-) A-I      intronic chr13:108156417(-) A-I      intronic chr13:108377180(-) A-I      intronic chr13:108508544(-) A-I      intronic chr13:108367688(-) A-I      intronic chr13:108510809(-) A-I      intronic chr13:108377964(-) A-I      intronic chr13:108438759(-) A-I      intronic chr13:107988553(-) A-I      intronic chr13:108444196(-) A-I      intronic chr13:108164625(-) A-I      intronic chr13:108508454(-) A-I      intronic chr13:108231711(-) A-I      intronic chr13:107992668(-) A-I      intronic chr13:108411586(-) A-I      intronic chr13:108347305(-) A-I      intronic chr13:108175089(-) A-I      intronic chr13:108338961(-) A-I      intronic chr13:108379054(-) A-I      intronic chr13:108220458(-) A-I      intronic chr13:107963249(-) A-I      intronic chr13:108076664(-) A-I      intronic chr13:108377937(-) A-I      intronic chr13:108504349(-) A-I      intronic chr13:107938933(-) A-I      intronic chr13:108514010(-) A-I      intronic chr13:107951663(-) A-I      intronic chr13:108508501(-) A-I      intronic chr13:108429195(-) A-I      intronic chr13:108263977(-) A-I      intronic chr13:107992626(-) A-I      intronic chr13:108124445(-) A-I      intronic chr13:107992617(-) A-I      intronic chr13:108377864(-) A-I      intronic chr13:108504289(-) A-I      intronic chr13:107991291(-) A-I      intronic chr13:108098322(-) A-I      intronic chr13:108120132(-) A-I      intronic chr13:108366860(-) A-I      intronic chr13:107940069(-) A-I      intronic chr13:107945518(-) A-I      intronic chr13:107945533(-) A-I      intronic chr13:107945557(-) A-I      intronic chr13:107945562(-) A-I      intronic chr13:108373619(-) A-I      intronic chr13:108117006(-) A-I      intronic chr13:108449692(-) A-I      intronic chr13:108378006(-) A-I      intronic chr13:108076745(-) A-I      intronic chr13:108347304(-) A-I      intronic chr13:108379409(-) A-I      intronic chr13:108444225(-) A-I      intronic chr13:107963109(-) A-I      intronic chr13:108312256(-) A-I      intronic chr13:107940083(-) A-I      intronic chr13:108348414(-) A-I      intronic chr13:108162319(-) A-I      intronic chr13:108432984(-) A-I      intronic chr13:108312259(-) A-I      intronic chr13:108251579(-) A-I      intronic chr13:108504429(-) A-I      intronic chr13:108164630(-) A-I      intronic chr13:108122364(-) A-I      intronic chr13:108379137(-) A-I      intronic chr13:108337527(-) A-I      intronic chr13:108274376(-) A-I      intronic chr13:108312558(-) A-I      intronic chr13:108504249(-) A-I      intronic chr13:108312566(-) A-I      intronic chr13:108175080(-) A-I      intronic chr13:108337657(-) A-I      intronic chr13:108379203(-) A-I      intronic chr13:108508396(-) A-I      intronic chr13:108503188(-) A-I      intronic chr13:108510871(-) A-I      intronic chr13:108312274(-) A-I      intronic chr13:107922207(-) A-I      intronic chr13:108377895(-) A-I      intronic chr13:108312594(-) A-I      intronic chr13:108504324(-) A-I      intronic chr13:107963098(-) A-I      intronic chr13:108366946(-) A-I      intronic chr13:108124673(-) A-I      intronic chr13:107920609(-) A-I      intronic chr13:108090984(-) A-I      intronic chr13:108112187(-) A-I      intronic chr13:108378033(-) A-I      intronic chr13:108348415(-) A-I      intronic chr13:107940228(-) A-I      intronic chr13:108506977(-) A-I      intronic chr13:108507160(-) A-I      intronic chr13:108504423(-) A-I      intronic chr13:108312254(-) A-I      intronic chr13:108335495(-) A-I      intronic chr13:107992738(-) A-I      intronic chr13:108264219(-) A-I      intronic chr13:108506964(-) A-I      intronic chr13:108379152(-) A-I      intronic chr13:108504422(-) A-I      intronic chr13:108504377(-) A-I      intronic chr13:107917919(-) A-I      intronic chr13:108231578(-) A-I      intronic chr13:108070287(-) A-I      intronic chr13:108033749(-) A-I      intronic chr13:107976374(-) A-I      intronic chr13:108231635(-) A-I      intronic chr13:108220454(-) A-I      intronic chr13:108366767(-) A-I      intronic chr13:108070269(-) A-I      intronic chr13:108449642(-) A-I      intronic chr13:108090962(-) A-I      intronic chr13:108376977(-) A-I      intronic chr13:108338870(-) A-I      intronic chr13:108264185(-) A-I      intronic chr13:107985466(-) A-I      intronic chr13:107945493(-) A-I      intronic chr13:108379147(-) A-I      intronic chr13:108162251(-) A-I      intronic chr13:108449587(-) A-I      intronic chr13:107985248(-) A-I      intronic chr13:108170231(-) A-I      intronic chr13:108267392(-) A-I      intronic chr13:108267404(-) A-I      intronic chr13:108413667(-) A-I      intronic chr13:108076624(-) A-I      intronic chr13:107960814(-) A-I      intronic chr13:108444269(-) A-I      intronic chr13:108120199(-) A-I      intronic chr13:108070246(-) A-I      intronic chr13:107951670(-) A-I      intronic chr13:108337513(-) A-I      intronic chr13:108015825(-) A-I      intronic chr13:108312531(-) A-I      intronic chr13:108068466(-) A-I      intronic chr13:108507053(-) A-I      intronic chr13:108367823(-) A-I      intronic chr13:108347219(-) A-I      intronic chr13:108164679(-) A-I      intronic chr13:107920446(-) A-I      intronic chr13:108432985(-) A-I      intronic chr13:108070144(-) A-I      intronic chr13:108338838(-) A-I      intronic chr13:108338918(-) A-I      intronic chr13:107951657(-) A-I      intronic chr13:108274742(-) A-I      intronic chr13:108367558(-) A-I      intronic chr13:107962749(-) A-I      intronic chr13:108422534(-) A-I      intronic chr13:108506976(-) A-I      intronic chr13:108070285(-) A-I      intronic chr13:108162283(-) A-I      intronic chr13:108347317(-) A-I      intronic chr13:107951073(-) A-I      intronic chr13:107938817(-) A-I      intronic chr13:108504396(-) A-I      intronic chr13:108070152(-) A-I      intronic chr13:108381897(-) A-I      intronic chr13:108504242(-) A-I      intronic chr13:108411662(-) A-I      intronic chr13:108338853(-) A-I      intronic chr13:108267318(-) A-I      intronic chr13:108377048(-) A-I      intronic chr13:107962714(-) A-I      intronic chr13:107960646(-) A-I      intronic chr13:108353569(-) A-I      intronic chr13:107992653(-) A-I      intronic chr13:107922233(-) A-I      intronic chr13:108339255(-) A-I      intronic chr13:107836234(-) A-I      intronic chr13:108377799(-) A-I      intronic chr13:108507139(-) A-I      intronic chr13:108312683(-) A-I      intronic chr13:108376972(-) A-I      intronic chr13:108221636(-) A-I      intronic chr13:108175068(-) A-I      intronic chr13:108366758(-) A-I      intronic chr13:107940191(-) A-I      intronic chr13:108413653(-) A-I      intronic chr13:108107622(-) A-I      intronic chr13:108339243(-) A-I      intronic chr13:108377910(-) A-I      intronic chr13:108107406(-) A-I      intronic chr13:108339376(-) A-I      intronic chr13:108504285(-) A-I      intronic chr13:108353550(-) A-I      intronic chr13:108339398(-) A-I      intronic chr13:108267245(-) A-I      intronic chr13:107950858(-) A-I      intronic chr13:108366824(-) A-I      intronic chr13:107992600(-) A-I      intronic chr13:108391050(-) A-I      intronic chr13:107960661(-) A-I      intronic chr13:108384181(-) A-I      intronic chr13:108378002(-) A-I      intronic chr13:108076626(-) A-I      intronic chr13:108488477(-) A-I      intronic chr13:108432971(-) A-I      intronic chr13:108020941(-) A-I      intronic chr13:107992594(-) A-I      intronic chr13:108156384(-) A-I      intronic chr13:108312528(-) A-I      intronic chr13:107980407(-) A-I      intronic chr13:108312258(-) A-I      intronic chr13:108383918(-) A-I      intronic chr13:108367699(-) A-I      intronic chr13:108053050(-) A-I      intronic chr13:108107604(-) A-I      intronic chr13:108444244(-) A-I      intronic chr13:108411587(-) A-I      intronic chr13:108106659(-) A-I      intronic chr13:108347416(-) A-I      intronic chr13:108345280(-) A-I      intronic chr13:108508398(-) A-I      intronic chr13:107992770(-) A-I      intronic chr13:108384162(-) A-I      intronic chr13:108366770(-) A-I      intronic chr13:107940087(-) A-I      intronic chr13:108106637(-) A-I      intronic chr13:108068451(-) A-I      intronic chr13:107940202(-) A-I      intronic chr13:108312759(-) A-I      intronic chr13:108312257(-) A-I      intronic chr13:108366771(-) A-I      intronic chr13:108375034(-) A-I      intronic chr13:108384182(-) A-I      intronic chr13:108379005(-) A-I      intronic chr13:107992702(-) A-I      intronic chr13:108106958(-) A-I      intronic chr13:108144520(-) A-I      intronic chr13:108120167(-) A-I      intronic chr13:108362449(-) A-I      intronic chr13:108337659(-) A-I      intronic chr13:108373594(-) A-I      intronic chr13:108263976(-) A-I      intronic chr13:108444484(-) A-I      intronic chr13:107932407(-) A-I      intronic chr13:108335590(-) A-I      intronic chr13:108070297(-) A-I      intronic chr13:108507056(-) A-I      intronic chr13:108312661(-) A-I      intronic chr13:108156338(-) A-I      intronic chr13:107938815(-) A-I      intronic chr13:108312197(-) A-I      intronic chr13:108391160(-) A-I      intronic chr13:108374673(-) A-I      intronic chr13:108490947(-) A-I      intronic chr13:108373598(-) A-I      intronic chr13:108373595(-) A-I      intronic chr13:108374732(-) A-I      intronic chr13:108335527(-) A-I      intronic chr13:108229546(-) A-I      intronic chr13:108112210(-) A-I      intronic chr13:108374663(-) A-I      intronic chr13:108445271(-) A-I      intronic chr13:107936136(-) A-I      intronic chr13:108251601(-) A-I      intronic chr13:108444485(-) A-I      intronic chr13:108507098(-) A-I      intronic chr13:108194387(-) A-I      intronic chr13:107941148(-) A-I      intronic chr13:108433953(-) A-I      intronic chr13:108444857(-) A-I      intronic chr13:108504417(-) A-I      intronic chr13:108068629(-) A-I      intronic chr13:108489562(-) A-I      intronic chr13:108411685(-) A-I      intronic chr13:108258810(-) A-I      intronic chr13:108068644(-) A-I      intronic chr13:108162370(-) A-I      intronic chr13:108338968(-) A-I      intronic chr13:108229545(-) A-I      intronic chr13:108411672(-) A-I      intronic chr13:107992775(-) A-I      intronic chr13:108373584(-) A-I      intronic chr13:107988443(-) A-I      intronic chr13:108066213(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	FAM155A	chr13:108377799(-) A-I intron -    15545495 chr13:108377864(-) A-I intron -    15545495 chr13:108377875(-) A-I intron -    15545495 chr13:108377886(-) A-I intron -    15545495 chr13:108377895(-) A-I intron -    15545495 chr13:108377964(-) A-I intron -    15545495 chr13:108378033(-) A-I intron -    15545495

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	FAM155A	chr13:107822687-107822688(-) m6A 3'UTR       25456834//24981863 chr13:107822693-107822694(-) m6A 3'UTR       25456834//24981863 chr13:107822713-107822714(-) m6A 3'UTR       25456834//24981863 chr13:107822769-107822770(-) m6A 3'UTR       24209618//25456834//24981863 chr13:107822863-107822864(-) m6A CDS       24209618//25456834//24981863//22575960 chr13:107822898-107822899(-) m6A CDS       24209618//25456834//24981863//22575960 chr13:107822908-107822909(-) m6A CDS       24209618//25456834//24981863//22575960 chr13:107822973-107822974(-) m6A CDS       24209618//25456834//24981863//22575960 chr13:107822988-107822989(-) m6A CDS       24209618//25456834//24981863//22575960 chr13:107823017-107823018(-) m6A CDS       24209618//25456834//24981863//22575960 chr13:107823047-107823048(-) m6A CDS       24209618//25456834//24981863 chr13:108118846-108118847(-) m6A intron       - chr13:108118875-108118876(-) m6A intron       - chr13:108518036-108518037(-) m6A CDS       24209618//24981863 chr13:108518135-108518136(-) m6A CDS       24209618//25456834//24981863//27773535 chr13:108518210-108518211(-) m6A CDS       24209618//25456834//24981863//27773535//22575960 chr13:108518294-108518295(-) m6A CDS       24209618//25456834//24981863 chr13:108518363-108518364(-) m6A CDS       24209618//25456834//24981863 chr13:108518436-108518437(-) m6A CDS       24209618//25456834//24981863 chr13:108518465-108518466(-) m6A CDS       24209618//25456834//27773536 chr13:108518581-108518582(-) m6A CDS       24209618//25456834//27773536 chr13:108518738-108518739(-) m6A CDS       24209618 chr13:108518863-108518864(-) m6A CDS       24209618 chr13:108519027-108519028(-) m6A 5'UTR       25456834

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-19b-1-5p	Exosome Jurkat-derived T cell line (J77cl20)     21505438 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Mesenchymal stem cells     -
	FAM155A	Cytosol K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-19b-1-5p
Interactor2: FAM155A

Evidence Support:

Weak-Evidence	RNA-Seq
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	31570108	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	ARPE-19 human RPE cells	Interactor2 expression	None
Description	Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).