Detail Information

Basic Information:


  VIRBase ID:  

HHID00007767

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-19b-1-5p:           ILDR2:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-19b-1-5p ILDR2
miRBase
Accession/Entrez ID		 MIMAT0004491 387597
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - C1orf32//dJ782G3.1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-19b-1-5p
rs1330845252 chr13:91351221    G/A
rs771220050 chr13:91351229    C/T
rs1259633726 chr13:91351212    T/G
rs1279688822 chr13:91351213    G/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR ILDR2
chr1:166941386(-) A-I      intronic
chr1:166883151(-) A-I      3'UTR
chr1:166940898(-) A-I      intronic
chr1:166934988(-) A-I      intronic
chr1:166883186(-) A-I      3'UTR
chr1:166936899(-) A-I      intronic
chr1:166883136(-) A-I      3'UTR
chr1:166883150(-) A-I      3'UTR
chr1:166883132(-) A-I      3'UTR
chr1:166895903(-) A-I      intronic
chr1:166934948(-) A-I      intronic
chr1:166936894(-) A-I      intronic
chr1:166883275(-) A-I      3'UTR
chr1:166883269(-) A-I      3'UTR
chr1:166883188(-) A-I      3'UTR
chr1:166883230(-) A-I      3'UTR
chr1:166891465(-) A-I      intronic
chr1:166936872(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED ILDR2
chr1:166883151(-) A-G exon 3'UTR    22484847
chr1:166934948(-) A-G intron -    22484847
chr1:166940898(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ILDR2
chr1:166877331-166877332(-) m6A exon       -
chr1:166885945-166885946(-) m6A 3'UTR//intron       22608085
chr1:166885965-166885966(-) m6A 3'UTR//intron       22608085
chr1:166886018-166886019(-) m6A 3'UTR//intron       22608085
chr1:166886029-166886030(-) m6A 3'UTR//intron       22608085
chr1:166886037-166886038(-) m6A 3'UTR//intron       22608085
chr1:166886053-166886054(-) m6A 3'UTR//intron       22608085
chr1:166886437-166886438(-) m6A 3'UTR//intron       25456834
chr1:166886445-166886446(-) m6A 3'UTR//intron       25456834
chr1:166886486-166886487(-) m6A 3'UTR//intron       25456834
chr1:166886987-166886988(-) m6A 3'UTR//intron       -
chr1:166887000-166887001(-) m6A 3'UTR//intron       -
chr1:166887033-166887034(-) m6A 3'UTR//exon       -
chr1:166887117-166887118(-) m6A 3'UTR//exon       27371828//22608085
chr1:166887127-166887128(-) m6A 3'UTR//exon       27371828//22608085
chr1:166887150-166887151(-) m6A 3'UTR//exon       27371828//22608085
chr1:166887201-166887202(-) m6A 3'UTR//exon       27371828//22608085
chr1:166887311-166887312(-) m6A 3'UTR//exon       22608085
chr1:166887842-166887843(-) m6A 3'UTR       22608085
chr1:166887888-166887889(-) m6A 3'UTR       22608085
chr1:166887961-166887962(-) m6A 3'UTR       24209618//25456834//24981863//27371828//22608085
chr1:166888017-166888018(-) m6A 3'UTR       25456834//24981863//27371828//22608085
chr1:166888184-166888185(-) m6A 3'UTR       24209618//24981863//22608085
chr1:166888245-166888246(-) m6A 3'UTR       24209618//24981863//22608085
chr1:166888253-166888254(-) m6A 3'UTR       24209618//24981863//22608085
chr1:166888289-166888290(-) m6A 3'UTR       24209618//24981863//22608085
chr1:166888295-166888296(-) m6A 3'UTR       24209618//24981863//22608085
chr1:166888360-166888361(-) m6A 3'UTR       24209618//24981863//22608085
chr1:166888419-166888420(-) m6A 3'UTR       24209618//25456834//24981863//27371828//22608085
chr1:166888506-166888507(-) m6A 3'UTR       24209618//25456834//27371828//22608085
chr1:166888521-166888522(-) m6A 3'UTR       24209618//25456834//27371828//22608085
chr1:166888535-166888536(-) m6A 3'UTR//CDS       24209618//25456834//27371828//22608085
chr1:166888540-166888541(-) m6A 3'UTR//CDS       24209618//25456834//22608085
chr1:166888549-166888550(-) m6A 3'UTR//CDS       24209618//25456834//22608085
chr1:166888555-166888556(-) m6A 3'UTR//CDS       24209618//25456834//22608085
chr1:166889945-166889946(-) m6A CDS//intron       24209618//22608085
chr1:166890318-166890319(-) m6A CDS//intron       27371828//27773536
chr1:166891943-166891944(-) m6A CDS//intron       -
chr1:166892003-166892004(-) m6A CDS//intron       -
chr1:166892026-166892027(-) m6A CDS//intron       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-19b-1-5p
Exosome Jurkat-derived T cell line (J77cl20)     21505438
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Mesenchymal stem cells     -
ILDR2
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-19b-1-5p
Interactor2: ILDR2

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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