Detail Information

Basic Information:


  VIRBase ID:  

HHID00007609

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-19b-1-5p:           RRAGD:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-19b-1-5p RRAGD
miRBase
Accession/Entrez ID		 MIMAT0004491 58528
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - bA11D8.2.1//RAGD

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-19b-1-5p
rs1330845252 chr13:91351221    G/A
rs771220050 chr13:91351229    C/T
rs1259633726 chr13:91351212    T/G
rs1279688822 chr13:91351213    G/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR RRAGD
chr6:90111044(-) A-I      intronic
chr6:90111032(-) A-I      intronic
chr6:90113040(-) A-I      intronic
chr6:90094201(-) A-I      intronic
chr6:90104741(-) A-I      intronic
chr6:90104733(-) A-I      intronic
chr6:90113042(-) A-I      intronic
chr6:90111105(-) A-I      intronic
chr6:90113052(-) A-I      intronic
chr6:90111082(-) A-I      intronic
chr6:90111115(-) A-I      intronic
chr6:90111125(-) A-I      intronic
chr6:90079399(-) A-I      intronic
chr6:90092225(-) A-I      intronic
chr6:90092226(-) A-I      intronic
chr6:90093649(-) A-I      intronic
chr6:90093740(-) A-I      intronic
chr6:90094217(-) A-I      intronic
chr6:90079373(-) A-I      intronic
chr6:90079380(-) A-I      intronic
chr6:90106326(-) A-I      intronic
chr6:90113055(-) A-I      intronic
chr6:90113158(-) A-I      intronic
chr6:90079343(-) A-I      intronic
chr6:90111053(-) A-I      intronic
chr6:90111062(-) A-I      intronic
chr6:90111066(-) A-I      intronic
chr6:90079391(-) A-I      intronic
chr6:90111101(-) A-I      intronic
chr6:90100843(-) A-I      intronic
chr6:90076001(-) A-I      3'UTR
chr6:90076127(-) A-I      3'UTR
chr6:90076042(-) A-I      3'UTR
chr6:90076067(-) A-I      3'UTR
chr6:90076211(-) A-I      3'UTR
chr6:90076244(-) A-I      3'UTR
chr6:90076002(-) A-I      3'UTR
chr6:90076142(-) A-I      3'UTR
chr6:90076075(-) A-I      3'UTR
chr6:90113627(-) A-I      intronic
chr6:90094135(-) A-I      intronic
chr6:90090569(-) A-I      intronic
chr6:90104916(-) A-I      intronic
chr6:90111821(-) A-I      intronic
chr6:90094155(-) A-I      intronic
chr6:90079342(-) A-I      intronic
chr6:90094200(-) A-I      intronic
chr6:90094161(-) A-I      intronic
chr6:90113520(-) A-I      intronic
chr6:90094506(-) A-I      intronic
chr6:90094291(-) A-I      intronic
chr6:90092242(-) A-I      intronic
chr6:90113101(-) A-I      intronic
chr6:90111141(-) A-I      intronic
chr6:90106242(-) A-I      intronic
chr6:90076201(-) A-I      3'UTR
chr6:90075990(-) A-I      3'UTR
chr6:90076242(-) A-I      3'UTR
chr6:90076129(-) A-I      3'UTR
chr6:90076054(-) A-I      3'UTR
chr6:90076209(-) A-I      3'UTR
chr6:90076044(-) A-I      3'UTR
chr6:90076139(-) A-I      3'UTR
chr6:90094136(-) A-I      intronic
chr6:90094115(-) A-I      intronic
chr6:90079375(-) A-I      intronic
chr6:90094713(-) A-I      intronic
chr6:90079220(-) A-I      intronic
chr6:90106284(-) A-I      intronic
chr6:90111905(-) A-I      intronic
chr6:90104973(-) A-I      intronic
chr6:90106256(-) A-I      intronic
chr6:90079364(-) A-I      intronic
chr6:90111904(-) A-I      intronic
chr6:90106411(-) A-I      intronic
chr6:90079265(-) A-I      intronic
chr6:90106558(-) A-I      intronic
chr6:90104934(-) A-I      intronic
chr6:90113492(-) A-I      intronic
chr6:90094109(-) A-I      intronic
chr6:90094203(-) A-I      intronic
chr6:90113391(-) A-I      intronic
chr6:90113462(-) A-I      intronic
chr6:90111114(-) A-I      intronic
chr6:90111937(-) A-I      intronic
chr6:90081092(-) A-I      intronic
chr6:90112975(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED RRAGD
chr6:90094093(-) A-I intron -    15545495
chr6:90094109(-) A-I intron -    15545495
chr6:90094115(-) A-I intron -    15545495
chr6:90094131(-) A-I intron -    15545495
chr6:90094135(-) A-I intron -    15545495
chr6:90094136(-) A-I intron -    15545495   //22327324
chr6:90094155(-) A-I intron -    15545495
chr6:90094203(-) A-I intron -    22327324
chr6:90081005(-) A-G intron -    22484847
chr6:90092242(-) A-G intron -    22484847
chr6:90094102(-) T-C intron -    22484847
chr6:90094131(-) A-G intron -    22484847
chr6:90094135(-) A-G intron -    22484847
chr6:90094136(-) A-G intron -    22484847
chr6:90094161(-) A-G intron -    22484847
chr6:90094200(-) A-G intron -    22484847
chr6:90094203(-) A-G intron -    22484847
chr6:90094291(-) A-G intron -    22484847
chr6:90113101(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase RRAGD
chr6:90076041-90076042(-) m6A 3'UTR       -
chr6:90076076-90076077(-) m6A 3'UTR       -
chr6:90076131-90076132(-) m6A 3'UTR       -
chr6:90077588-90077589(-) m6A 3'UTR       24981863//27773535//22608085
chr6:90077681-90077682(-) m6A 3'UTR       24981863//27773535//22608085
chr6:90077742-90077743(-) m6A 3'UTR       24981863//27773535//22608085
chr6:90077794-90077795(-) m6A CDS       27773535//22608085
chr6:90097045-90097046(-) m6A CDS//exon//intron       24209618//24981863//27371828//22608085
chr6:90097097-90097098(-) m6A CDS//exon//intron       24209618//24981863//27371828//22608085
chr6:90097107-90097108(-) m6A CDS//exon//intron       24209618//24981863//27371828//22608085
chr6:90097186-90097187(-) m6A CDS//exon//intron       24981863//27773535//27371828//22608085
chr6:90097302-90097303(-) m6A CDS//exon//intron       27773535//27371828//27773536
chr6:90121196-90121197(-) m6A exon//intron       27371828//27773536
chr6:90121215-90121216(-) m6A exon//intron       25456834//27371828//27773536
chr6:90121584-90121585(-) m6A 5'UTR//CDS       24209618//25456834//24981863//27371828//27773536
chr6:90121623-90121624(-) m6A 5'UTR//CDS       24209618//25456834//24981863//27371828//27773536
chr6:90121749-90121750(-) m6A 5'UTR       24209618//27371828//27773536
chr6:90121813-90121814(-) m6A 5'UTR       24209618//27371828//27773536
chr6:90121877-90121878(-) m6A 5'UTR       24209618//27371828//27773536
chr6:90121883-90121884(-) m6A 5'UTR       24209618//27371828//27773536
chr6:90121891-90121892(-) m6A 5'UTR       24209618//27371828//27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-19b-1-5p
Exosome Jurkat-derived T cell line (J77cl20)     21505438
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Mesenchymal stem cells     -
RRAGD
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-19b-1-5p
Interactor2: RRAGD

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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