Basic Information:

  VIRBase ID:  

HHID00007389

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-19b-1-5p:  MIMAT0004491          RAB13:  NR_073553     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-19b-1-5p	RAB13
miRBase Accession/Entrez ID	MIMAT0004491	5872
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	GIG4

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-19b-1-5p	rs1330845252 chr13:91351221    G/A rs771220050 chr13:91351229    C/T rs1259633726 chr13:91351212    T/G rs1279688822 chr13:91351213    G/T

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	RAB13	chr1:153954275-153954276(-) m6A 3'UTR//exon       24209618//25456834//24981863//27773535//22608085 chr1:153954299-153954300(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//22608085 chr1:153954528-153954529(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085 chr1:153954539-153954540(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085 chr1:153954571-153954572(-) m6A 3'UTR//exon       24284625//24209618//24981863//28052920//27773535//27371828//27773536//22575960//22608085 chr1:153954599-153954600(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//27773536//22575960 chr1:153954615-153954616(-) m6A CDS//exon       24284625//24209618//24981863//26404942//27773535//27371828//27773536 chr1:153954717-153954718(-) m6A exon//intron       24209618//24981863//27773535//27371828//27773536 chr1:153954847-153954848(-) m6A exon//intron       24981863 chr1:153954897-153954898(-) m6A CDS//exon       24981863 chr1:153954942-153954943(-) m6A exon//intron       24981863 chr1:153955042-153955043(-) m6A CDS//exon       24981863 chr1:153955125-153955126(-) m6A exon//intron       24981863 chr1:153955164-153955165(-) m6A exon//intron       24981863 chr1:153955246-153955247(-) m6A CDS//exon       24981863//27773535 chr1:153955313-153955314(-) m6A exon//intron       24981863//27773535 chr1:153955396-153955397(-) m6A exon//intron       27773535 chr1:153955976-153955977(-) m6A exon//intron       27773535 chr1:153956028-153956029(-) m6A 5'UTR//CDS//exon       27773535 chr1:153956054-153956055(-) m6A 5'UTR//CDS//exon       27773535 chr1:153957207-153957208(-) m6A 5'UTR//CDS//exon       27773535 chr1:153958620-153958621(-) m6A CDS//exon       24981863 chr1:153958648-153958649(-) m6A CDS//exon       24981863 chr1:153958665-153958666(-) m6A CDS//exon       24981863 chr1:153958818-153958819(-) m6A 5'UTR//exon       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-19b-1-5p	Exosome Jurkat-derived T cell line (J77cl20)     21505438 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Mesenchymal stem cells     -
	RAB13	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)     - Exosome Blood     - Nucleus HeLa-S3 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-19b-1-5p
Interactor2: RAB13

Evidence Support:

Weak-Evidence	RNA-Seq
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	31570108	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	ARPE-19 human RPE cells	Interactor2 expression	None
Description	Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).