Detail Information

Basic Information:


  VIRBase ID:  

HHID00007268

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-19a-5p FP15737
miRBase
Accession/Entrez ID		 MIMAT0004490 FP15737
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-19a-5p
rs1162564162 chr13:91350912    A/G
rs1170543143 chr13:91350916    T/C
rs1388542964 chr13:91350918    G/C
rs1403138754 chr13:91350923    A/C
rs1442807536 chr13:91350921    C/G
rs764765453 chr13:91350924    CAAG/C
rs1051963210 chr13:91350909    T/C
rs756288295 chr13:91350905    G/A
rs780315531 chr13:91350911    C/T

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase FP15737
chr8:23432221-23432222(+) m6A 3'UTR       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-19a-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-19a-5p
Interactor2: FP15737

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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