Detail Information

Basic Information:


  VIRBase ID:  

HHID00007011

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-19a-5p:           WDR82:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-19a-5p WDR82
miRBase
Accession/Entrez ID		 MIMAT0004490 80335
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - MST107//MSTP107//PRO2730//PRO34047//SWD2//TMEM113//WDR82A

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-19a-5p
rs1162564162 chr13:91350912    A/G
rs1170543143 chr13:91350916    T/C
rs1388542964 chr13:91350918    G/C
rs1403138754 chr13:91350923    A/C
rs1442807536 chr13:91350921    C/G
rs764765453 chr13:91350924    CAAG/C
rs1051963210 chr13:91350909    T/C
rs756288295 chr13:91350905    G/A
rs780315531 chr13:91350911    C/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR WDR82
chr3:52299310(-) A-I      intronic
chr3:52299188(-) A-I      intronic
chr3:52308836(-) A-I      intronic
chr3:52308976(-) A-I      intronic
chr3:52298872(-) A-I      intronic
chr3:52303007(-) A-I      intronic
chr3:52304354(-) A-I      intronic
chr3:52298840(-) A-I      intronic
chr3:52298837(-) A-I      intronic
chr3:52297062(-) A-I      intronic
chr3:52297061(-) A-I      intronic
chr3:52309075(-) A-I      intronic
chr3:52309137(-) A-I      intronic
chr3:52309174(-) A-I      intronic
chr3:52305938(-) A-I      intronic
chr3:52305988(-) A-I      intronic
chr3:52305981(-) A-I      intronic
chr3:52306558(-) A-I      intronic
chr3:52307220(-) A-I      intronic
chr3:52302991(-) A-I      intronic
chr3:52307866(-) A-I      intronic
chr3:52300649(-) A-I      intronic
chr3:52307905(-) A-I      intronic
chr3:52307823(-) A-I      intronic
chr3:52307805(-) A-I      intronic
chr3:52307713(-) A-I      intronic
chr3:52307704(-) A-I      intronic
chr3:52300657(-) A-I      intronic
chr3:52307339(-) A-I      intronic
chr3:52307243(-) A-I      intronic
chr3:52302905(-) A-I      intronic
chr3:52302939(-) A-I      intronic
chr3:52303025(-) A-I      intronic
chr3:52303058(-) A-I      intronic
chr3:52307919(-) A-I      intronic
chr3:52303081(-) A-I      intronic
chr3:52303299(-) A-I      intronic
chr3:52303311(-) A-I      intronic
chr3:52303382(-) A-I      intronic
chr3:52303616(-) A-I      intronic
chr3:52303699(-) A-I      intronic
chr3:52304273(-) A-I      intronic
chr3:52307910(-) A-I      intronic
chr3:52304300(-) A-I      intronic
chr3:52304315(-) A-I      intronic
chr3:52307911(-) A-I      intronic
chr3:52304331(-) A-I      intronic
chr3:52305888(-) A-I      intronic
chr3:52305958(-) A-I      intronic
chr3:52307352(-) A-I      intronic
chr3:52307814(-) A-I      intronic
chr3:52308411(-) A-I      intronic
chr3:52310325(-) A-I      intronic
chr3:52307815(-) A-I      intronic
chr3:52297110(-) A-I      intronic
chr3:52303732(-) A-I      intronic
chr3:52303013(-) A-I      intronic
chr3:52307338(-) A-I      intronic
chr3:52303001(-) A-I      intronic
chr3:52298841(-) A-I      intronic
chr3:52300627(-) A-I      intronic
chr3:52303024(-) A-I      intronic
chr3:52307411(-) A-I      intronic
chr3:52307702(-) A-I      intronic
chr3:52299168(-) A-I      intronic
chr3:52307722(-) A-I      intronic
chr3:52305949(-) A-I      intronic
chr3:52302946(-) A-I      intronic
chr3:52302952(-) A-I      intronic
chr3:52306023(-) A-I      intronic
chr3:52308381(-) A-I      intronic
chr3:52307734(-) A-I      intronic
chr3:52303027(-) A-I      intronic
chr3:52289065(-) A-I      3'UTR
chr3:52289055(-) A-I      3'UTR
chr3:52300743(-) A-I      intronic
chr3:52304318(-) A-I      intronic
chr3:52306006(-) A-I      intronic
chr3:52303663(-) A-I      intronic
chr3:52307802(-) A-I      intronic
chr3:52299269(-) A-I      intronic
chr3:52307733(-) A-I      intronic
chr3:52308654(-) A-I      intronic
chr3:52307856(-) A-I      intronic
chr3:52298883(-) A-I      intronic
chr3:52307811(-) A-I      intronic
chr3:52303104(-) A-I      intronic
chr3:52299865(-) A-I      intronic
chr3:52299204(-) A-I      intronic
chr3:52303588(-) A-I      intronic
chr3:52303008(-) A-I      intronic
chr3:52307762(-) A-I      intronic
chr3:52299730(-) A-I      intronic
chr3:52307347(-) A-I      intronic
chr3:52303659(-) A-I      intronic
chr3:52304423(-) A-I      intronic
chr3:52307917(-) A-I      intronic
chr3:52307855(-) A-I      intronic
chr3:52299149(-) A-I      intronic
chr3:52305966(-) A-I      intronic
chr3:52307776(-) A-I      intronic
chr3:52308835(-) A-I      intronic
chr3:52303063(-) A-I      intronic
chr3:52302889(-) A-I      intronic
chr3:52299688(-) A-I      intronic
chr3:52299864(-) A-I      intronic
chr3:52299158(-) A-I      intronic
chr3:52303004(-) A-I      intronic
chr3:52307858(-) A-I      intronic
chr3:52299075(-) A-I      intronic
chr3:52303582(-) A-I      intronic
chr3:52307786(-) A-I      intronic
chr3:52303683(-) A-I      intronic
chr3:52304329(-) A-I      intronic
chr3:52307742(-) A-I      intronic
chr3:52304409(-) A-I      intronic
chr3:52305865(-) A-I      intronic
chr3:52306529(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED WDR82
chr3:52305888(-) A-I intron -    21960545
chr3:52298841(-) A-G intron -    22484847
chr3:52299204(-) A-G intron -    22484847
chr3:52300627(-) A-G intron -    22484847
chr3:52300733(-) A-G intron -    22484847
chr3:52300743(-) A-G intron -    22484847
chr3:52302946(-) A-G intron -    22484847
chr3:52302984(-) A-G intron -    22484847
chr3:52303001(-) A-G intron -    22484847
chr3:52303013(-) A-G intron -    22484847
chr3:52303063(-) A-G intron -    22484847
chr3:52303582(-) A-G intron -    22484847
chr3:52303588(-) A-G intron -    22484847
chr3:52303634(-) A-G intron -    22484847
chr3:52303646(-) A-G intron -    22484847
chr3:52303663(-) A-G intron -    22484847
chr3:52303683(-) A-G intron -    22484847
chr3:52303694(-) A-G intron -    22484847
chr3:52303732(-) A-G intron -    22484847
chr3:52303740(-) A-G intron -    22484847
chr3:52304423(-) A-G intron -    22484847
chr3:52305949(-) A-G intron -    22484847
chr3:52306006(-) A-G intron -    22484847
chr3:52306023(-) A-G intron -    22484847
chr3:52307338(-) A-G intron -    22484847
chr3:52307347(-) A-G intron -    22484847
chr3:52307352(-) A-G intron -    22484847
chr3:52307722(-) A-G intron -    22484847
chr3:52307734(-) A-G intron -    22484847
chr3:52307762(-) A-G intron -    22484847
chr3:52307776(-) A-G intron -    22484847
chr3:52307786(-) A-G intron -    22484847
chr3:52307811(-) A-G intron -    22484847
chr3:52307813(-) A-G intron -    22484847
chr3:52307814(-) A-G intron -    22484847
chr3:52307815(-) A-G intron -    22484847
chr3:52307855(-) A-G intron -    22484847
chr3:52307856(-) A-G intron -    22484847
chr3:52307857(-) A-G intron -    22484847
chr3:52307858(-) A-G intron -    22484847
chr3:52307917(-) A-G intron -    22484847
chr3:52308835(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase WDR82
chr3:52288984-52288985(-) m6A 3'UTR//exon       24284625//24209618
chr3:52289054-52289055(-) m6A 3'UTR//exon       24209618
chr3:52289150-52289151(-) m6A 3'UTR//exon       24209618
chr3:52290832-52290833(-) m6A 3'UTR//exon       24981863//27773535
chr3:52290932-52290933(-) m6A 3'UTR//exon       24284625//24209618//27773535//22575960
chr3:52290946-52290947(-) m6A 3'UTR//exon       24284625//24209618//27773535//22575960
chr3:52290979-52290980(-) m6A 3'UTR//exon       24284625//24209618//27773535
chr3:52290991-52290992(-) m6A 3'UTR//exon       24284625//27773535
chr3:52291235-52291236(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr3:52291287-52291288(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr3:52291298-52291299(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr3:52291314-52291315(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr3:52291398-52291399(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr3:52291441-52291442(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr3:52291452-52291453(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr3:52292623-52292624(-) m6A CDS//exon       24284625//24209618//22608085
chr3:52312312-52312313(-) m6A 5'UTR//CDS//intron       27371828//22575960
chr3:52312318-52312319(-) m6A 5'UTR//CDS//intron       27371828//22575960
chr3:52312527-52312528(-) m1A 5'UTR//intron       26863196//26863410
chr3:52312547-52312548(-) m6A 5'UTR//intron       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085
chr3:52312632-52312633(-) m6A 5'UTR//intron       24284625//25456834//24981863//27371828//27773536//22575960//22608085
chr3:52318594-52318595(-) m6A 5'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-19a-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
WDR82
Chromatin K562 cells     -
Cytosol HCC cell line (HepG2)     -
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-19a-5p
Interactor2: WDR82

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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