Detail Information

Basic Information:


  VIRBase ID:  

HHID00006964

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-19a-5p:           TRMT5:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-19a-5p TRMT5
miRBase
Accession/Entrez ID		 MIMAT0004490 57570
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - COXPD26//KIAA1393//TRM5

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-19a-5p
rs1162564162 chr13:91350912    A/G
rs1170543143 chr13:91350916    T/C
rs1388542964 chr13:91350918    G/C
rs1403138754 chr13:91350923    A/C
rs1442807536 chr13:91350921    C/G
rs764765453 chr13:91350924    CAAG/C
rs1051963210 chr13:91350909    T/C
rs756288295 chr13:91350905    G/A
rs780315531 chr13:91350911    C/T

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase TRMT5
chr14:61438324-61438325(-) m6A 3'UTR       27773535
chr14:61438353-61438354(-) m6A 3'UTR       27773535
chr14:61438387-61438388(-) m6A 3'UTR       27773535
chr14:61438568-61438569(-) m6A 3'UTR       24981863//22608085
chr14:61438580-61438581(-) m6A 3'UTR       24981863//22608085
chr14:61438601-61438602(-) m6A 3'UTR       24981863//22608085
chr14:61438649-61438650(-) m6A 3'UTR       24981863
chr14:61439091-61439092(-) m6A 3'UTR       24284625//25456834//24981863//27773535//22608085
chr14:61439168-61439169(-) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085
chr14:61439252-61439253(-) m6A 3'UTR       24209618//25456834//24981863//27773535//22608085
chr14:61439380-61439381(-) m6A 3'UTR       27773535
chr14:61439393-61439394(-) m6A 3'UTR       27773535
chr14:61440725-61440726(-) m6A 3'UTR       24981863
chr14:61442204-61442205(-) m6A CDS       27773535
chr14:61442209-61442210(-) m6A CDS       27773535
chr14:61442263-61442264(-) m6A CDS       27773535
chr14:61442476-61442477(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22608085
chr14:61442499-61442500(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22608085
chr14:61442550-61442551(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//22608085
chr14:61442563-61442564(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//22608085
chr14:61442599-61442600(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//22608085
chr14:61442677-61442678(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr14:61442745-61442746(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr14:61442754-61442755(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr14:61442772-61442773(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr14:61442833-61442834(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr14:61444244-61444245(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr14:61445958-61445959(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr14:61445986-61445987(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr14:61446003-61446004(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr14:61446081-61446082(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr14:61446093-61446094(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr14:61446150-61446151(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//22608085
chr14:61446207-61446208(-) m6A CDS       24284625//24209618//24981863//28052920//26404942//27773535//22608085
chr14:61446338-61446339(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//27371828//22575960//22608085
chr14:61446353-61446354(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//27371828//22575960//22608085
chr14:61446363-61446364(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//27371828//22575960//22608085
chr14:61446407-61446408(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//27371828//22575960//22608085
chr14:61446422-61446423(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//27371828//22575960//22608085
chr14:61446428-61446429(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//27371828//22575960//22608085
chr14:61446509-61446510(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr14:61446561-61446562(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr14:61447587-61447588(-) m6A CDS//intron       24284625//24209618//24981863//22608085
chr14:61447789-61447790(-) m6A 5'UTR//CDS       25456834//24981863//27773536
chr14:61447810-61447811(-) m6A 5'UTR//CDS       25456834//24981863//27773536
chr14:61448041-61448042(-) m6A 5'UTR       24981863
chr14:61448047-61448048(-) m6A 5'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-19a-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
TRMT5
Exosome Blood     -
Nucleus K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-19a-5p
Interactor2: TRMT5

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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