Detail Information

Basic Information:


  VIRBase ID:  

HHID00006922

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-19a-5p:           DZANK1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-19a-5p DZANK1
miRBase
Accession/Entrez ID		 MIMAT0004490 55184
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - ANKRD64//C20orf12//C20orf84

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-19a-5p
rs1162564162 chr13:91350912    A/G
rs1170543143 chr13:91350916    T/C
rs1388542964 chr13:91350918    G/C
rs1403138754 chr13:91350923    A/C
rs1442807536 chr13:91350921    C/G
rs764765453 chr13:91350924    CAAG/C
rs1051963210 chr13:91350909    T/C
rs756288295 chr13:91350905    G/A
rs780315531 chr13:91350911    C/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR DZANK1
chr20:18430355(-) A-I      intronic
chr20:18384582(-) A-I      intronic
chr20:18384588(-) A-I      intronic
chr20:18384608(-) A-I      intronic
chr20:18384612(-) A-I      intronic
chr20:18384613(-) A-I      intronic
chr20:18384632(-) A-I      intronic
chr20:18384640(-) A-I      intronic
chr20:18441192(-) A-I      intronic
chr20:18441184(-) A-I      intronic
chr20:18427903(-) A-I      intronic
chr20:18408613(-) A-I      intronic
chr20:18408104(-) A-I      intronic
chr20:18408075(-) A-I      intronic
chr20:18443519(-) A-I      intronic
chr20:18371974(-) A-I      intronic
chr20:18380119(-) A-I      intronic
chr20:18372002(-) A-I      intronic
chr20:18404999(-) A-I      intronic
chr20:18380149(-) A-I      intronic
chr20:18371829(-) A-I      intronic
chr20:18371691(-) A-I      intronic
chr20:18371657(-) A-I      intronic
chr20:18443500(-) A-I      intronic
chr20:18379558(-) A-I      intronic
chr20:18375771(-) A-I      intronic
chr20:18380153(-) A-I      intronic
chr20:18372137(-) A-I      intronic
chr20:18443525(-) A-I      intronic
chr20:18443535(-) A-I      intronic
chr20:18431666(-) A-I      intronic
chr20:18379707(-) A-I      intronic
chr20:18409010(-) A-I      intronic
chr20:18431657(-) A-I      intronic
chr20:18441130(-) A-I      intronic
chr20:18441129(-) A-I      intronic
chr20:18408111(-) A-I      intronic
chr20:18391356(-) A-I      intronic
chr20:18379687(-) A-I      intronic
chr20:18431783(-) A-I      intronic
chr20:18364732(-) A-I      3'UTR
chr20:18431754(-) A-I      intronic
chr20:18442422(-) A-I      intronic
chr20:18431784(-) A-I      intronic
chr20:18408865(-) A-I      intronic
chr20:18380034(-) A-I      intronic
chr20:18408091(-) A-I      intronic
chr20:18442311(-) A-I      intronic
chr20:18430977(-) A-I      intronic
chr20:18384584(-) A-I      intronic
chr20:18430938(-) A-I      intronic
chr20:18431860(-) A-I      intronic
chr20:18430333(-) A-I      intronic
chr20:18431772(-) A-I      intronic
chr20:18371637(-) A-I      intronic
chr20:18431861(-) A-I      intronic
chr20:18431728(-) A-I      intronic
chr20:18430947(-) A-I      intronic
chr20:18430935(-) A-I      intronic
chr20:18430998(-) A-I      intronic
chr20:18431655(-) A-I      intronic
chr20:18371677(-) A-I      intronic
chr20:18391373(-) A-I      intronic
chr20:18431027(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase DZANK1
chr20:18364918-18364919(-) m6A 3'UTR       24981863
chr20:18365023-18365024(-) m6A 3'UTR       25456834//24981863//22608085
chr20:18365071-18365072(-) m6A 3'UTR//CDS       25456834//24981863//22608085
chr20:18365085-18365086(-) m6A 3'UTR//CDS       25456834//24981863//22608085
chr20:18365145-18365146(-) m6A 3'UTR//CDS       25456834//22608085
chr20:18365167-18365168(-) m6A 3'UTR//CDS       25456834//22608085
chr20:18432523-18432524(-) m6A 3'UTR//intron       27773535
chr20:18432545-18432546(-) m6A 3'UTR//intron       27773535
chr20:18432600-18432601(-) m6A CDS//intron       27773535
chr20:18433279-18433280(-) m6A 5'UTR//CDS//intron       27773535

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-19a-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
DZANK1
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-19a-5p
Interactor2: DZANK1

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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