Detail Information

Basic Information:


  VIRBase ID:  

HHID00006683

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-19a-5p:           SLAMF1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-19a-5p SLAMF1
miRBase
Accession/Entrez ID		 MIMAT0004490 6504
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - CD150//CDw150//SLAM

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-19a-5p
rs1162564162 chr13:91350912    A/G
rs1170543143 chr13:91350916    T/C
rs1388542964 chr13:91350918    G/C
rs1403138754 chr13:91350923    A/C
rs1442807536 chr13:91350921    C/G
rs764765453 chr13:91350924    CAAG/C
rs1051963210 chr13:91350909    T/C
rs756288295 chr13:91350905    G/A
rs780315531 chr13:91350911    C/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SLAMF1
chr1:160587723(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED SLAMF1
chr1:160586913(-) G-A intron -    22484847
chr1:160586955(-) A-T intron -    22484847
chr1:160586956(-) A-T intron -    22484847
chr1:160586967(-) T-C intron -    22484847
chr1:160587723(-) A-G intron -    22484847
chr1:160605543(-) C-A intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SLAMF1
chr1:160578928-160578929(-) m6A 3'UTR       26404942
chr1:160579628-160579629(-) m6A 3'UTR       26404942
chr1:160579650-160579651(-) m6A 3'UTR       26404942
chr1:160579662-160579663(-) m6A 3'UTR       -
chr1:160579669-160579670(-) m6A 3'UTR       -
chr1:160579676-160579677(-) m6A 3'UTR       -
chr1:160579746-160579747(-) m6A 3'UTR       -
chr1:160579859-160579860(-) m6A 3'UTR       -
chr1:160579866-160579867(-) m6A 3'UTR       -
chr1:160579873-160579874(-) m6A 3'UTR       -
chr1:160579908-160579909(-) m6A 3'UTR       -
chr1:160579932-160579933(-) m6A 3'UTR       -
chr1:160579985-160579986(-) m6A 3'UTR       -
chr1:160580071-160580072(-) m6A 3'UTR//CDS       28052920//26404942//27371828
chr1:160580152-160580153(-) m6A 3'UTR//intron       28052920//26404942//27371828
chr1:160580180-160580181(-) m6A 3'UTR//intron       28052920//26404942//27773535//27371828
chr1:160580193-160580194(-) m6A 3'UTR//intron       28052920//26404942//27773535//27371828
chr1:160580212-160580213(-) m6A 3'UTR//intron       28052920//26404942//27773535//27371828
chr1:160580239-160580240(-) m6A 3'UTR//intron       28052920//26404942//27773535//27371828
chr1:160580257-160580258(-) m6A 3'UTR//intron       28052920//26404942//27773535//27371828
chr1:160580312-160580313(-) m6A 3'UTR//intron       28052920//26404942//27371828
chr1:160580370-160580371(-) m6A 3'UTR//intron       28052920//26404942//27371828
chr1:160580443-160580444(-) m6A 3'UTR//intron       28052920//26404942//27371828
chr1:160580476-160580477(-) m6A 3'UTR//intron       28052920//26404942//27371828
chr1:160580483-160580484(-) m6A 3'UTR//intron       28052920//26404942//27371828
chr1:160580493-160580494(-) m6A 3'UTR//intron       28052920//26404942//27371828
chr1:160580516-160580517(-) m6A 3'UTR//intron       28052920//26404942//27371828
chr1:160580528-160580529(-) m6A 3'UTR//intron       28052920//26404942//27371828
chr1:160580584-160580585(-) m6A CDS//intron       28052920//26404942//27371828
chr1:160582332-160582333(-) m6A CDS//intron       -
chr1:160582355-160582356(-) m6A CDS//intron       -
chr1:160585535-160585536(-) m6A intron       -
chr1:160585542-160585543(-) m6A intron       -
chr1:160589571-160589572(-) m6A CDS//intron       -
chr1:160604441-160604442(-) m6A CDS//intron       28052920
chr1:160604545-160604546(-) m6A CDS//intron       28052920//26404942
chr1:160604593-160604594(-) m6A CDS//intron       26404942
chr1:160604633-160604634(-) m6A CDS//intron       26404942
chr1:160607168-160607169(-) m6A CDS//exon       28052920//26404942//27371828
chr1:160607180-160607181(-) m6A CDS//exon       28052920//26404942//27371828
chr1:160607225-160607226(-) m6A CDS//exon       28052920//26404942

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-19a-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
SLAMF1
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-19a-5p
Interactor2: SLAMF1

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence miRDB
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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