Detail Information

Basic Information:


  VIRBase ID:  

HHID00006450

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-519e-3p:           ZNF286B:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-519e-3p ZNF286B
miRBase
Accession/Entrez ID		 MIMAT0002829 729288
Organism Homo sapiens Homo sapiens
Category miRNA pseudo
Alias - FOXO3B//ZNF286C//ZNF286L//ZNF590

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-519e-3p
rs1320260913 chr19:53680012    T/TA
rs748109530 chr19:53680008    G/A
rs756692397 chr19:53679994    T/C
rs762638742 chr19:53679970    CTTTCTGTTTGAAAGAAAACAAAGTGCCTCCTTTTAGAGTG/C
rs778834695 chr19:53679997    C/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR ZNF286B
chr17:18582899(-) A-I      intronic
chr17:18583226(-) A-I      intronic
chr17:18582866(-) A-I      intronic
chr17:18583161(-) A-I      intronic
chr17:18577876(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ZNF286B
chr17:18565282-18565283(-) m6A 3'UTR//CDS       24981863//22608085
chr17:18565339-18565340(-) m6A 3'UTR//CDS       24981863//22608085
chr17:18565356-18565357(-) m6A 3'UTR//CDS       24981863//22608085
chr17:18565423-18565424(-) m6A 3'UTR//CDS       24981863//22608085
chr17:18565450-18565451(-) m6A 3'UTR//CDS       24981863//22608085
chr17:18565479-18565480(-) m6A 3'UTR//CDS       24981863//22608085
chr17:18565507-18565508(-) m6A 3'UTR//CDS       24981863//22608085
chr17:18565563-18565564(-) m6A 3'UTR//CDS       24981863
chr17:18565941-18565942(-) m6A 3'UTR//CDS       22608085
chr17:18565951-18565952(-) m6A 3'UTR//CDS       22608085
chr17:18566008-18566009(-) m6A 3'UTR//CDS       22608085
chr17:18566065-18566066(-) m6A 3'UTR//CDS       24981863
chr17:18566092-18566093(-) m6A 3'UTR//CDS       24981863
chr17:18566109-18566110(-) m6A 3'UTR//CDS       24981863
chr17:18566129-18566130(-) m6A 3'UTR//CDS       24981863
chr17:18566140-18566141(-) m6A 3'UTR//CDS       24981863
chr17:18566256-18566257(-) m6A 3'UTR//CDS       22608085
chr17:18566302-18566303(-) m6A 3'UTR//CDS       27371828//22608085
chr17:18566396-18566397(-) m6A 3'UTR//CDS       24981863//22608085
chr17:18566467-18566468(-) m6A 3'UTR//CDS       22608085
chr17:18566472-18566473(-) m6A CDS       22608085
chr17:18566538-18566539(-) m6A CDS       22608085
chr17:18574265-18574266(-) m6A intron       24981863
chr17:18574345-18574346(-) m6A intron       24981863
chr17:18574397-18574398(-) m6A intron       24981863
chr17:18574403-18574404(-) m6A intron       24981863
chr17:18574445-18574446(-) m6A intron       24981863
chr17:18574620-18574621(-) m6A intron       27773535
chr17:18574643-18574644(-) m6A intron       27773535
chr17:18574769-18574770(-) m6A intron       24981863
chr17:18574808-18574809(-) m6A intron       24981863
chr17:18574823-18574824(-) m6A intron       24284625//24981863
chr17:18574833-18574834(-) m6A intron       24284625//24981863
chr17:18574877-18574878(-) m6A intron       24284625//24981863
chr17:18574890-18574891(-) m6A intron       24284625//24981863
chr17:18574916-18574917(-) m6A intron       24284625//24981863//22608085
chr17:18574930-18574931(-) m6A intron       24284625//24981863//22608085
chr17:18575020-18575021(-) m6A intron       24284625//24981863//22608085
chr17:18575084-18575085(-) m6A intron       24284625//24209618//25456834//24981863//27371828//27773536//22608085
chr17:18575144-18575145(-) m6A intron       24284625//24209618//25456834//24981863//27371828//27773536//22608085
chr17:18575316-18575317(-) m6A intron       24284625//27773536//22608085
chr17:18575413-18575414(-) m6A intron       24284625//24981863//27371828//22608085
chr17:18575475-18575476(-) m6A intron       24284625//24981863//22608085
chr17:18575557-18575558(-) m6A intron       24284625//24981863//22608085
chr17:18575616-18575617(-) m6A intron       24284625//24981863//22608085
chr17:18575715-18575716(-) m6A intron       24284625//24209618//24981863//22608085
chr17:18575748-18575749(-) m6A intron       24284625//24209618//24981863
chr17:18575763-18575764(-) m6A intron       24284625//24209618//24981863
chr17:18575919-18575920(-) m6A intron       24981863//27773536//22608085
chr17:18575952-18575953(-) m6A intron       25456834//24981863//27371828//27773536//22608085
chr17:18576183-18576184(-) m6A CDS//intron       27773536
chr17:18576268-18576269(-) m6A CDS//intron       27773536
chr17:18585193-18585194(-) m6A exon//intron       24981863
chr17:18585207-18585208(-) m6A exon//intron       24981863
chr17:18585226-18585227(-) m6A exon//intron       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-519e-3p
Exosome Brain tissue     23382797
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
ZNF286B
Chromatin K562 cells     -
Exosome Blood     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function
ncDR hsa-miR-519e-3p
Iodine Green 9956454 Drug sensitive
2-(2,4-Difluorophenyl)-4,5,6,7-tetrafluoro-1H-isoindole-1,3(2H)-dione 9905583 Drug sensitive
Kahalalide F 9898671 Drug resistant
CID 9604911 9604911 Drug sensitive
Actinomycin X4357G methoxime 9573583 Drug sensitive
Indolo[2,1-b]quinazoline-6,12-dione 73549 Drug sensitive
Venenatine 73061 Drug sensitive
Redoxal 72571 Drug sensitive
Piperidinium pentamethylenedithiocarbamate 72508 Drug sensitive
4-(2-Naphthylamino)phenol 7141 Drug sensitive
Tolonium chloride 7083 Drug sensitive
Sulbentine 67686 Drug sensitive
Reactive Blue 2 656725 Drug sensitive
(2R,3R,4S,5R)-2-(6-Benzylsulfanylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol 6477178 Drug sensitive
Vicenistatin 6438888 Drug sensitive
Verrucarin A 6326658 Drug sensitive
Deferoxamine hydrochloride 62880 Drug sensitive
Cytarabine 6253 Drug sensitive
Bizelesin 60794 Drug sensitive
Tributyrin 6050 Drug sensitive
Triethylenemelamine 5799 Drug sensitive
Teclothiazide potassium 56841138 Drug sensitive
(3beta)-3-((4-O-beta-D Glucopyranosyl-beta-D-xylopyranosyl)oxy)-14-hydroxy-19-oxocarda-4,20(22)-dienolide 56840951 Drug sensitive
Caracemide 54747 Drug sensitive
7Z-Plakortide H 5472712 Drug sensitive
Artelasticin 5471311 Drug sensitive
Antineoplastic-690266 5469577 Drug sensitive
3-Deazauridine 54684286 Drug sensitive
3,19-(4-Acetamido)benzylidineandrographolide 54612901 Drug sensitive
Herveline O 5459269 Drug sensitive
Betuletol 5459196 Drug sensitive
Cuspidatin C 5459164 Drug sensitive
Thiram 5455 Drug sensitive
Piritrexim isethionate 54368 Drug sensitive
(E)-1-(2,5-Dihydroxyphenyl)ethene-2-isonitrile 5388136 Drug sensitive
(1E,4E)-1,5-Dipyridin-3-ylpenta-1,4-dien-3-one 5382674 Drug sensitive
Crassin, acetate 5355441 Drug sensitive
Rozex 5353923 Drug sensitive
MX2 hydrochloride 5351347 Drug sensitive
Dihydro-5-azacytidine 5351280 Drug sensitive
7-(3-Methoxyphenyl)-N-(pyridin-4-ylmethylideneamino)-5H-pyrrolo[3,2-d]pyrimidin-4-amine 53239944 Drug sensitive
Vorinostat 5311 Drug sensitive
Improsulfan hydrochloride 5284401 Drug sensitive
Kekule 499328 Drug sensitive
Pyrimethamine 4993 Drug sensitive
10-Hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12-dodecahydro-1H-picene-4a-carboxylic acid 495604 Drug sensitive
Propyl gallate 4947 Drug resistant
1,4-Benzoquinone 4650 Drug sensitive
Melphalan 460612 Drug sensitive
Aclarubicin 451415 Drug sensitive
Ossirene 451379 Drug sensitive
Mycophenolic acid 446541 Drug sensitive
1-(4-(Benzyloxy)phenyl)-3-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl)phenyl)urea 44587530 Drug sensitive
Isopinnatal 44558939 Drug sensitive
Iproplatin 44214 Drug sensitive
Di-n-octyl-secalonsaure A 430141 Drug sensitive
S-(Dimethylarsino)-3-mercapto-1,2-propyl dibenzoate 406481 Drug sensitive
Aminopyrimidine-CH3 406278 Drug sensitive
Mechlorethamine 4033 Drug sensitive
Artelastin 399488 Drug sensitive
Cbz-[Lys3]-Didemnin B 398464 Drug resistant
Loratadine 3957 Drug sensitive
2,5-Bis(aziridin-1-yl)-3-(hydroxymethyl)-6-methylcyclohexa-2,5-diene-1,4-dione 394347 Drug sensitive
Sjg-136 393111 Drug sensitive
Leflunomide 3899 Drug sensitive
beta-Lapachone 3885 Drug sensitive
Lapachol 3884 Drug sensitive
Benzo[1,2-b:5,4-b']dithiophene-4,8-dione, 2-acetyl- 388028 Drug sensitive
3-(4-Fluorophenyl)-3-(4-hydroxy-2-methylphenyl)-2-benzofuran-1(3H)-one 387973 Drug resistant
1,3-Diphenyl-6-((triphenylphosphoranylidene)amino)-2,4(1H,3H)-pyrimidinedione 387460 Drug sensitive
Acetic acid,4,7,10-tetraazacyclododecane-1,7-diyl]bis 387352 Drug sensitive
L-LYS-L-p-NO2Phe-L-Ala-L-p-NO2PheNH2 386384 Drug sensitive
Stereoisomer of NSC 674066-O 384359 Drug sensitive
3-(4-Fluorophenyl)-3-(4-acetoxy-2-methylphenyl)phthalide 383342 Drug resistant
1-Azido-2-phenyl-3-phenalenone 381891 Drug sensitive
2-Acetyl-1,2-dihydroellipticine 376328 Drug resistant
Sanguilutine pseudobase 371258 Drug sensitive
1,2-Dimethyl-phenothiazone 369387 Drug sensitive
4-Nitro-6-(trifluoromethyl)-2,1,3-benzoselenadiazole 362897 Drug sensitive
Aplidazole C . TFA 362402 Drug sensitive
Predorine 333830 Drug sensitive
Rocaglamide 331783 Drug sensitive
Pinafide 327045 Drug sensitive
2,3-Dimethoxy-5-naphthalen-2-ylsulfanylcyclohexa-2,5-diene-1,4-dione 314728 Drug sensitive
Cytosine, 1beta-D-arabinofuranosyl-N(sup 4)-stearoyl- 304673 Drug sensitive
Flurocitabine 3034016 Drug sensitive
P-Ara-C 282479 Drug sensitive
Dichloroallyl lawsone 277767 Drug sensitive
6-Bromotoyocamycin 270861 Drug sensitive
2'-Deoxy-5-(trifluoromethyl)uridine 253083 Drug sensitive
2-(7-Aminotriazolo[4,5-d]pyrimidin-3-yl)-5-(hydroxymethyl)oxolane-3,4-diol 251928 Drug sensitive
2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-N-[2-(methylamino)ethyl]-1H-imidazo[4,5-c]pyridine-7-carboxamide 25023715 Drug resistant
9H-Purine, 6-(o-chlorobenzylthio)-9-(2-chloroethyl)- 246231 Drug sensitive
9H-Purine, 6-(benzylthio)-9-(2-chloroethyl)- 246230 Drug sensitive
Antimycin A3 245869 Drug sensitive
Prumycin HCl 24197905 Drug resistant
Cinerubin A hcl 24196924 Drug sensitive
9H-Purine, 2-amino-6-(o-chlorobenzylthio)-9-propyl- 239486 Drug sensitive
Spongiaquinone 23424796 Drug resistant
[(1S,2Z,4R,8R,9R,11R,13S)-13-Acetyloxy-1-hydroxy-2,11-dimethyl-7-methylidene-6-oxo-5,14-dioxatricyclo[9.2.1.04,8]tetradec-2-en-9-yl] 2-methylpropanoate 23255746 Drug sensitive
Amsacrine 2179 Drug sensitive
Pirarubicin hydrochloride 20846247 Drug sensitive
7,8-Dihydroxyflavone 1880 Drug sensitive
Sudan II 18386 Drug sensitive
4-Chloro-5-phenoxy-3H-1,2-dithiole-3-thione 16766044 Drug sensitive
Azaribine 16574 Drug sensitive
(2Z,9E,13Z,15E)-4',11-Dihydroxy-2,4',9-trimethylspiro[3-aza-1(2,4)-thiazolacyclohexadecaphanene-6,3'-[1,2]dithiolane]-9,13,15-triene-4,5',12-trione 2'-oxide 154730760 Drug sensitive
Methyl (3'R)-3,4',9',10-tetrahydroxy-3'-[(2S,4R,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-7'-methoxy-5',8',9-trioxospiro[3,4-dihydropyrano[4,3-g]chromene-2,2'-3H-benzo[f][1]benzofuran]-7-carboxylate 137326876 Drug sensitive
C8, Carbonyl prodigiosine 135540857 Drug sensitive
5-[(E)-[Amino(methyl)amino]azo]-1H-imidazole-4-carboxamide 135493930 Drug sensitive
Cysteine, S-[(4-aminocarbonyl-1H-imidazol-5-yl)azo]- 135493928 Drug sensitive
Emofolin sodium 135475347 Drug sensitive
8-Azahypoxanthine 135410720 Drug sensitive
Raltitrexed 135400182 Drug sensitive
DTIC-Dome 135398738 Drug sensitive
(2S,4S,5R)-20-De(1-hydroxypropyl)-6-demethyl-2,6-diethyl-5-hydroxy-20-(1-hydroxybutyl)lysocellin 124081057 Drug sensitive
p-Toluquinone 11122 Drug sensitive
Gentian violet 11057 Drug sensitive
Withajardin C 102469053 Drug sensitive
(7S,9S)-7-[[(3As,4S,7aS)-1-[[(3aS,4S,7aS)-4-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-2,3a,4,6,7,7a-hexahydropyrano[4,3-d][1,3]oxazol-1-yl]methyl]-4-methyl-2,3a,4,6,7,7a-hexahydropyrano[4,3-d][1,3]oxazol-6-yl]oxy]-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione 101713728 Drug sensitive
(1S,2R,4R,6S,11R,12S,15R,18S,19R,20R,21S,23R,26R)-15-Hydroxy-11,18,21-trimethyl-5,17,24,28,29-pentaoxanonacyclo[17.9.1.11,20.02,12.04,6.06,11.015,19.018,23.021,26]triacont-8-ene-10,16,25,30-tetrone 101528280 Drug sensitive
Erigerol 101318126 Drug sensitive
[(1S,2S,4Z,8Z,12R,13S)-12-Hydroxy-4,8,12-trimethyl-16-methylidene-15-oxo-14-oxabicyclo[11.3.1]heptadeca-4,8-dien-2-yl] acetate 100921072 Drug sensitive
Tocladesine 100299 Drug sensitive
(1R,2E,6R,10E,11aS,13S,14aR)-6-(2-(benzyloxy)ethyl)-1,13-dihydroxy-6,7,8,9,12,13,14,14a-octahydro-1H-cyclopenta[f][1]oxacyclotridecin-4(11aH)-one - Drug resistant
2,3-dihydro-1,2-syn-3-[phenylseleno]brefeldin a - Drug resistant
9-methoxy-5-hydroxycamptothecin - Drug resistant
tp4ek - Drug resistant
(Z)-N-phenyl-3-(3,4,5-trimethoxystyryl)pyridin-2-amine - Drug sensitive
1,2-naphthoquinone, 3,7-dimethyl- - Drug sensitive
1h-benzimidazole, 5,5'-dithiobis[2-(trifluoromethyl)- (9ci) - Drug sensitive
2-[(3,4-dicloro)anilino]-3-phenyl-5,7-diamino quinoxaline - Drug sensitive
3',4',5'-trimethoxy-3-hydroxy flavone - Drug sensitive
4-(2-pyridinyl)-5h-1,2,3-dithiazole-5-thione - Drug sensitive
4-[3-(3,4-dihydro-1H-isoquinolin-2-yl)prop-1-en-2-yl]-N-pyrazin-2-ylbenzamide - Drug sensitive
4-quinazolone, 7-amino-3-(4-methoxyphenyl)-, hydrate - Drug sensitive
5.alpha.,25d-spirostan-3.beta.-ol glycoside - Drug sensitive
9h-quino[4,3,2-de][1,10]phenanthrolin-9-one, 5-methoxy- - Drug sensitive
acetamide, n-(2-mercaptoethyl)-, benzoate (6ci, 7ci) - Drug sensitive
b676297k277 3',4'-deoxypsorospermin 3',4'-chlorohydrin - Drug sensitive
benzo[1,2-c:4,5-c']dipyrrole-1,3,5,7(2h,6h)-tetraimine - Drug sensitive
benzofurazan, 4-nitro-7-(2-pyridinylthio)-, n-oxide - Drug sensitive
bersaldegenin 1,3,5-orthoacetate - Drug sensitive
cis-2-hydroxymethyl-4-(5'-bromocytosin-1'-yl)-1,3-dioxolane - Drug sensitive
furan-2(3h)-one, 5-(4-methylphenyl)-3,3-diphenyl- - Drug sensitive
isoflavone, 5,7-dihydroxy-4'-nitro- - Drug sensitive
mercury, tetrakis(acetato)(2,3,4,5-thiophenetetrayl)tetra- - Drug sensitive
n,n'-bis(oxydiethylene)thiocarbamoylsulfenamide - Drug sensitive
phenol, 4,4'-(5,5'-biisoxazole-3,3'-diyl)bis- - Drug sensitive
propan-1-one, 2,3-dichloro-1,3-bis(4-methylphenyl)- - Drug sensitive
propanedinitrile, [(3,5-dibromo-2-ethoxyphenyl)methylene]- - Drug sensitive
(Z)-3-((2-(4-(trifluoromethyl)phenyl)-3H-benzo[d]imidazol-5-yl)methylene)indolin-2-one - Drug sensitive
[bis(aminomethyl)diethylsilane]dichloroplatinum (ii) - Drug sensitive
7-propanoyltaxol - Drug sensitive
Aminopterin Derivative - Drug sensitive
Annamycin Liposomal - Drug sensitive
antineoplastic-d665839 - Drug sensitive
Camptothecin Derivative - Drug sensitive
Carboxyphthalatoplatinum - Drug sensitive
chlorobis(4-ethyltropolonato)bismuth(iii) - Drug sensitive
CI-921: amsacrine derivative - Drug sensitive
Indenoisoquinoline derivative - Drug sensitive
insulin-methotrexate conjugate - Drug sensitive
merophan - Drug sensitive
mitaplatin - Drug sensitive
n-myristoyl-(s)-phenylalaninal diethylcetal - Drug sensitive
organosulfur compound - Drug sensitive
trimethyl(phenylthio)stannane - Drug sensitive
Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-519e-3p
Alocrest 60780 Drug interaction    RC00005536
5-Fluorouracil 3385 Drug interaction    RC00005535
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00005534
Tamoxifen 2733526 Drug interaction    RC00005537
Resource Symbol Drug Name PubChem ID
RNAactDrug ZNF286B
6-Amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide       9956222
Benzamide, N-[4-[2-ethyl-4-(3-methylphenyl)-5-thiazolyl]-2-pyridinyl]-       9952773
1,2-Ethanediamine, N-(1,8-dimethylimidazo(1,2-a)quinoxalin-4-yl)-, monohydrochloride       9926054
Tivozanib       9911830
5-(4-Fluorophenyl)-2-ureidothiophene-3-carboxamide       9903786
PI-103       9884685
Osi-930       9868037
N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide       9826528
9H-Purine, 6-(ethylthio)-9-beta-D-ribofuranosyl-(8CI)(9CI)       95846
6-Benzylthioinosine       95263
(3Ar,4R,6E,10E,11aR)-6-methyl-3-methylidene-4-[(E)-3-methylpent-2-enoyl]oxy-2-oxo-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-10-carboxylic acid       92276668
Benzethonium chloride       8478
3-Amino-7-(dimethylamino)-5-phenylphenazinium chloride       75442
Cyclopentenyl cytosine       72828
5-Methyl-1,10-phenanthroline       72791
Nonactin       72519
N-(3-Methylphenyl)-4-pyridin-4-yl-1,3-thiazol-2-amine       704473
(S)-N-Hydroxy-4-(3-methyl-2-phenylbutanamido)benzamide       6918848
Belinostat       6918638
Temsirolimus       6918289
N-(5-(4-Chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide       6852167
3-Hydroxy-3'-nitro-2-naphthanilide       67277
Antineoplastic-631448       6711565
AICA ribonucleotide       65110
Tanespimycin       6505803
Ispinesib mesylate       6450816
Pelitinib       6445562
4-(N-Hydroxyacetamido)stilbene       6433723
Imiquimod       57469
4-(2,4-Dinitrophenyl)sulfanyl-1-methyl-2-nitrobenzene       57359203
Phyllanthastatin 1       5477587
Mito-tempol       54613387
Curromycin A.B mixture       54608021
Aspergillic acid, dehydrodeoxy-       54600217
(10R,13R,16R,19S)-16-Butan-2-yl-3-(3-chloro-2-hydroxypropyl)-10,11,14-trimethyl-13-propan-2-yl-4-oxa-1,8,11,14,17-pentazabicyclo[17.3.0]docosane-2,5,9,12,15,18-hexone       5459202
2-Methylolivacinium acetate       5458752
Rubremetinium chloride       5351504
N-[4-[(4-Ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide       53340664
Desoximetasone       5311067
Vorinostat       5311
Isotretinoin       5282379
Alsterpaullone       5005498
Tubastatin A       49850262
Alectinib       49806720
2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one       4713
2-[(4s)-6-(4-Chlorophenyl)-8-Methoxy-1-Methyl-4h-[1,2,4]triazolo[4,3-A][1,4]benzodiazepin-4-Yl]-N-Ethylacetamide       46943432
3-(4-(4-(2-(3-((Dimethylamino)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)-1-ethyl-1H-pyrazol-3-yl)phenyl)-1,1-dimethylurea       46885626
N-(6,6-Dimethyl-5-(1-methylpiperidine-4-carbonyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)-3-methylbutanamide       46191454
N-(2,2,2-Trifluoroethyl)-N-{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}benzenesulfonamide       447912
1-(6,7-Dimethoxyquinazolin-4-yl)-3-(pyridin-2-yl)-1H-1,2,4-triazol-5-amine       44551660
1-Benzyl-3-hexadecyl-2-methylimidazolium chloride       44219704
Refametinib       44182295
Foretinib       42642645
Amethopterin       4112
Janus Red B       407803
6-Methoxy-2-(4-hydroxyphenyl)benzothiazole       404997
1-(2-(Hydroxymethyl)-1,3-dioxolan-4-yl)cytosine       381525
Sporanox       3793
2-Chloro-3-(3-(N-morpholino)propylamino)-naphthazarine       379081
1,5,9,13,17-Pentathiacycloeicosane       373845
Arabinosyl cytosine palmitate       35731
Illudin M       344199
5-Fluorouracil       3385
Cetalkonium chloride       31202
AT 116, benzylamine salt       282523
[1]Benzothieno[3,2-h]isoquinoline       278923
Flavacol       278143
[5-[2,4-Bis((3S)-3-methylmorpholin-4-yl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl]methanol       25262965
2-(4-Methyl-1,4-diazepan-1-yl)-N-((5-methylpyrazin-2-yl)methyl)-5-oxo-5H-benzo[4,5]thiazolo[3,2-a][1,8]naphthyridine-6-carboxamide       25257557
Cabozantinib       25102847
Navitoclax       24978538
Tert-Butyl (4-(3-((7-(hydroxyamino)-7-oxoheptyl)carbamoyl)isoxazol-5-yl)phenyl)carbamate       24951314
Quizartinib       24889392
Ponatinib       24826799
10-(6'-Ubiquinolyl)decyltriphenylphosphonium       24783759
4-(6,6-Dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)-2-((1r,4r)-4-hydroxycyclohexylamino)benzamide       24772860
Arylidene-4-chloro       24202977
(2-Methoxy-9,10-dihydrophenanthren-3-yl)methyl-dimethyl-(phenylsulfanylmethyl)azanium;bromide       24200489
Arenaemycin E       24199350
N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide       24180719
Tricinolone acetophenonide       235856
2,7-Naphthalenedisulfonic acid, 3-hydroxy-4-(phenylazo)-, disodium salt       22142
6-Chloro-2-methoxy-9-[(5-piperidinopentyl)amino]acridine       219600
Nutlin-3       216345
8-Amino-5-methyl-6-phenylphenanthridin-5-ium bromide       21144180
Kinetin riboside       20345
8-Chloro-cyclicamp       17856967
Enzastaurin       176167
4-Methyl-3-(1-methyl-6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino)-N-(3-(trifluoromethyl)phenyl)benzamide       16747388
Gsk-690693       16725726
5-Chloro-2[(E)-2-(4-nitrophenyl)vinyl]-1H-benzimidazole       15373173
Docetaxel       148124
Homidium bromide       14710
Astrazon Orange R       135747272
(Z)-3-((3-((Dimethylamino)methyl)phenylamino)(phenyl)methylene)-N,N-dimethyl-2-oxoindoline-6-carboxamide       135659062
(E)-5-(2-(4-(2-(Dimethylamino)ethoxy)phenyl)-5-(pyridin-4-yl)-1H-imidazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime       135421339
Pac-1       135421197
Osi-027       135398516
Akt inhibitor VIII       135398501
Abiraterone       132971
Methotrexate       126941
Berberine chloride       12456
Dactolisib       11977753
N-[3-[[5-Bromo-4-[[2-(1H-imidazol-5-YL)ethyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide       11754511
Trametinib       11707110
Megestrol acetate       11683
4,4'-(6-(2-(Difluoromethyl)-1H-benzo[d]imidazol-1-yl)-1,3,5-triazine-2,4-diyl)dimorpholine       11647372
4-[2-(2-Chloro-4-fluoroanilino)-5-methyl-4-pyrimidinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-1H-pyrrole-2-carboxamide       11634725
Idelalisib       11625818
5-(3-Methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine       11617559
5-(2-Phenylpyrazolo[1,5-A]pyridin-3-YL)-1H-pyrazolo[3,4-C]pyridazin-3-amine       11493598
Linifanib       11485656
N-(6-Fluoro-1H-indazol-5-yl)-6-methyl-2-oxo-4-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1H-pyridine-5-carboxamide       11373846
Pararosaniline hydrochloride       11292
1-Phenyl-5-(4-(trifluoromethyl)phenyl)-1H-imidazole       11162021
Setoglaucine       107404
[(4-Methylphenyl)methyl](triphenyl)arsanium bromide       10672721
Dequalinium chloride       10649
Podofilox       10607
VX-702       10341154
2'-Deoxy-2'-fluorocytidine       101507
Selumetinib       10127622
Masitinib       10074640
1,4-benzenediamine (9ci), n-butyl-n'-phenyl-       -
1,4-dimethoxy-7-azaisoindole[2,1-a]quinoxalin-6(5h)-one       -
(2r,5r)-2-palmitoylamido-(3e)-octadecen-1,5-diol)       -
5,6-ethylenediquino[3,2-b       -
8-aniline-3,7-dimethyl-2,6-octadiene-s-l-cysteine       -
.alpha.-sarcin       -
Aminopterin Derivative       -
Basic Fuchsin       -
benzamide, n-(2,3-dimethylphenyl)-2-hydroxy-3-nitro- (9ci)       -
Bleomycin (50 uM)       -
Denileukin Diftitox Ontak       -
;(E)-2-methyl-10-(3,4,5-trimethoxybenzylidene)-5-(3,4,5-...       -
Genentech Cpd 10       -
g-tpp       -
JW-7-24-1       -
KIN001-236       -
KIN001-244       -
KIN001-260       -
KIN001-266       -
MPS-1-IN-1       -
naphtho[2,1-b]quinolizinium, 5-chloro-7-methyl- perchlorate       -
NPK76-II-72-1       -
nsc 701656 incorporated in micelles, 0.73% (w/w) of drug.       -
pararosaniline pamoate       -
progesterone, 11.beta.,17-dihydroxy-6.alpha.-methyl-       -
propanedinitrile, [(3,5-dibromo-2-ethoxyphenyl)methylene]-       -
protein toxin c 10 - mw approx. 6700       -
QL-X-138       -
QL-XI-92       -
QL-XII-47       -
riboprine(usan)       -
SB52334       -
sphinxolide c       -
THZ-2-102-1       -
TL-1-85       -
TL-2-105       -
triacetyl 13,14,15-isocrambescidin 800 hydrochloride       -
XMD13-2       -
XMD14-99       -
;(Z)-5-Chloro-2-(1-methyl-5-nitroimidazole-2-ylmethylene...       -
;(Z)-6-Chloro-2-(1-methyl-4-nitroimidazole-5-ylmethylene...       -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-519e-3p
Interactor2: ZNF286B

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

Starting a new search, please wait ...