Basic Information:

  VIRBase ID:  

HHID00006449

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-519e-3p:  MIMAT0002829          FAM169B:  NR_171054     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-519e-3p	FAM169B
miRBase Accession/Entrez ID	MIMAT0002829	283777
Organism	Homo sapiens	Homo sapiens
Category	miRNA	pseudo
Alias	-	-

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-519e-3p	rs1320260913 chr19:53680012    T/TA rs748109530 chr19:53680008    G/A rs756692397 chr19:53679994    T/C rs762638742 chr19:53679970    CTTTCTGTTTGAAAGAAAACAAAGTGCCTCCTTTTAGAGTG/C rs778834695 chr19:53679997    C/T

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-519e-3p	Exosome Brain tissue     23382797 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
	FAM169B	Exosome Blood     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function
ncDR	hsa-miR-519e-3p	Iodine Green 9956454 Drug sensitive 2-(2,4-Difluorophenyl)-4,5,6,7-tetrafluoro-1H-isoindole-1,3(2H)-dione 9905583 Drug sensitive Kahalalide F 9898671 Drug resistant CID 9604911 9604911 Drug sensitive Actinomycin X4357G methoxime 9573583 Drug sensitive Indolo[2,1-b]quinazoline-6,12-dione 73549 Drug sensitive Venenatine 73061 Drug sensitive Redoxal 72571 Drug sensitive Piperidinium pentamethylenedithiocarbamate 72508 Drug sensitive 4-(2-Naphthylamino)phenol 7141 Drug sensitive Tolonium chloride 7083 Drug sensitive Sulbentine 67686 Drug sensitive Reactive Blue 2 656725 Drug sensitive (2R,3R,4S,5R)-2-(6-Benzylsulfanylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol 6477178 Drug sensitive Vicenistatin 6438888 Drug sensitive Verrucarin A 6326658 Drug sensitive Deferoxamine hydrochloride 62880 Drug sensitive Cytarabine 6253 Drug sensitive Bizelesin 60794 Drug sensitive Tributyrin 6050 Drug sensitive Triethylenemelamine 5799 Drug sensitive Teclothiazide potassium 56841138 Drug sensitive (3beta)-3-((4-O-beta-D Glucopyranosyl-beta-D-xylopyranosyl)oxy)-14-hydroxy-19-oxocarda-4,20(22)-dienolide 56840951 Drug sensitive Caracemide 54747 Drug sensitive 7Z-Plakortide H 5472712 Drug sensitive Artelasticin 5471311 Drug sensitive Antineoplastic-690266 5469577 Drug sensitive 3-Deazauridine 54684286 Drug sensitive 3,19-(4-Acetamido)benzylidineandrographolide 54612901 Drug sensitive Herveline O 5459269 Drug sensitive Betuletol 5459196 Drug sensitive Cuspidatin C 5459164 Drug sensitive Thiram 5455 Drug sensitive Piritrexim isethionate 54368 Drug sensitive (E)-1-(2,5-Dihydroxyphenyl)ethene-2-isonitrile 5388136 Drug sensitive (1E,4E)-1,5-Dipyridin-3-ylpenta-1,4-dien-3-one 5382674 Drug sensitive Crassin, acetate 5355441 Drug sensitive Rozex 5353923 Drug sensitive MX2 hydrochloride 5351347 Drug sensitive Dihydro-5-azacytidine 5351280 Drug sensitive 7-(3-Methoxyphenyl)-N-(pyridin-4-ylmethylideneamino)-5H-pyrrolo[3,2-d]pyrimidin-4-amine 53239944 Drug sensitive Vorinostat 5311 Drug sensitive Improsulfan hydrochloride 5284401 Drug sensitive Kekule 499328 Drug sensitive Pyrimethamine 4993 Drug sensitive 10-Hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12-dodecahydro-1H-picene-4a-carboxylic acid 495604 Drug sensitive Propyl gallate 4947 Drug resistant 1,4-Benzoquinone 4650 Drug sensitive Melphalan 460612 Drug sensitive Aclarubicin 451415 Drug sensitive Ossirene 451379 Drug sensitive Mycophenolic acid 446541 Drug sensitive 1-(4-(Benzyloxy)phenyl)-3-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl)phenyl)urea 44587530 Drug sensitive Isopinnatal 44558939 Drug sensitive Iproplatin 44214 Drug sensitive Di-n-octyl-secalonsaure A 430141 Drug sensitive S-(Dimethylarsino)-3-mercapto-1,2-propyl dibenzoate 406481 Drug sensitive Aminopyrimidine-CH3 406278 Drug sensitive Mechlorethamine 4033 Drug sensitive Artelastin 399488 Drug sensitive Cbz-[Lys3]-Didemnin B 398464 Drug resistant Loratadine 3957 Drug sensitive 2,5-Bis(aziridin-1-yl)-3-(hydroxymethyl)-6-methylcyclohexa-2,5-diene-1,4-dione 394347 Drug sensitive Sjg-136 393111 Drug sensitive Leflunomide 3899 Drug sensitive beta-Lapachone 3885 Drug sensitive Lapachol 3884 Drug sensitive Benzo[1,2-b:5,4-b']dithiophene-4,8-dione, 2-acetyl- 388028 Drug sensitive 3-(4-Fluorophenyl)-3-(4-hydroxy-2-methylphenyl)-2-benzofuran-1(3H)-one 387973 Drug resistant 1,3-Diphenyl-6-((triphenylphosphoranylidene)amino)-2,4(1H,3H)-pyrimidinedione 387460 Drug sensitive Acetic acid,4,7,10-tetraazacyclododecane-1,7-diyl]bis 387352 Drug sensitive L-LYS-L-p-NO2Phe-L-Ala-L-p-NO2PheNH2 386384 Drug sensitive Stereoisomer of NSC 674066-O 384359 Drug sensitive 3-(4-Fluorophenyl)-3-(4-acetoxy-2-methylphenyl)phthalide 383342 Drug resistant 1-Azido-2-phenyl-3-phenalenone 381891 Drug sensitive 2-Acetyl-1,2-dihydroellipticine 376328 Drug resistant Sanguilutine pseudobase 371258 Drug sensitive 1,2-Dimethyl-phenothiazone 369387 Drug sensitive 4-Nitro-6-(trifluoromethyl)-2,1,3-benzoselenadiazole 362897 Drug sensitive Aplidazole C . TFA 362402 Drug sensitive Predorine 333830 Drug sensitive Rocaglamide 331783 Drug sensitive Pinafide 327045 Drug sensitive 2,3-Dimethoxy-5-naphthalen-2-ylsulfanylcyclohexa-2,5-diene-1,4-dione 314728 Drug sensitive Cytosine, 1beta-D-arabinofuranosyl-N(sup 4)-stearoyl- 304673 Drug sensitive Flurocitabine 3034016 Drug sensitive P-Ara-C 282479 Drug sensitive Dichloroallyl lawsone 277767 Drug sensitive 6-Bromotoyocamycin 270861 Drug sensitive 2'-Deoxy-5-(trifluoromethyl)uridine 253083 Drug sensitive 2-(7-Aminotriazolo[4,5-d]pyrimidin-3-yl)-5-(hydroxymethyl)oxolane-3,4-diol 251928 Drug sensitive 2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-N-[2-(methylamino)ethyl]-1H-imidazo[4,5-c]pyridine-7-carboxamide 25023715 Drug resistant 9H-Purine, 6-(o-chlorobenzylthio)-9-(2-chloroethyl)- 246231 Drug sensitive 9H-Purine, 6-(benzylthio)-9-(2-chloroethyl)- 246230 Drug sensitive Antimycin A3 245869 Drug sensitive Prumycin HCl 24197905 Drug resistant Cinerubin A hcl 24196924 Drug sensitive 9H-Purine, 2-amino-6-(o-chlorobenzylthio)-9-propyl- 239486 Drug sensitive Spongiaquinone 23424796 Drug resistant [(1S,2Z,4R,8R,9R,11R,13S)-13-Acetyloxy-1-hydroxy-2,11-dimethyl-7-methylidene-6-oxo-5,14-dioxatricyclo[9.2.1.04,8]tetradec-2-en-9-yl] 2-methylpropanoate 23255746 Drug sensitive Amsacrine 2179 Drug sensitive Pirarubicin hydrochloride 20846247 Drug sensitive 7,8-Dihydroxyflavone 1880 Drug sensitive Sudan II 18386 Drug sensitive 4-Chloro-5-phenoxy-3H-1,2-dithiole-3-thione 16766044 Drug sensitive Azaribine 16574 Drug sensitive (2Z,9E,13Z,15E)-4',11-Dihydroxy-2,4',9-trimethylspiro[3-aza-1(2,4)-thiazolacyclohexadecaphanene-6,3'-[1,2]dithiolane]-9,13,15-triene-4,5',12-trione 2'-oxide 154730760 Drug sensitive Methyl (3'R)-3,4',9',10-tetrahydroxy-3'-[(2S,4R,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-7'-methoxy-5',8',9-trioxospiro[3,4-dihydropyrano[4,3-g]chromene-2,2'-3H-benzo[f][1]benzofuran]-7-carboxylate 137326876 Drug sensitive C8, Carbonyl prodigiosine 135540857 Drug sensitive 5-[(E)-[Amino(methyl)amino]azo]-1H-imidazole-4-carboxamide 135493930 Drug sensitive Cysteine, S-[(4-aminocarbonyl-1H-imidazol-5-yl)azo]- 135493928 Drug sensitive Emofolin sodium 135475347 Drug sensitive 8-Azahypoxanthine 135410720 Drug sensitive Raltitrexed 135400182 Drug sensitive DTIC-Dome 135398738 Drug sensitive (2S,4S,5R)-20-De(1-hydroxypropyl)-6-demethyl-2,6-diethyl-5-hydroxy-20-(1-hydroxybutyl)lysocellin 124081057 Drug sensitive p-Toluquinone 11122 Drug sensitive Gentian violet 11057 Drug sensitive Withajardin C 102469053 Drug sensitive (7S,9S)-7-[[(3As,4S,7aS)-1-[[(3aS,4S,7aS)-4-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-2,3a,4,6,7,7a-hexahydropyrano[4,3-d][1,3]oxazol-1-yl]methyl]-4-methyl-2,3a,4,6,7,7a-hexahydropyrano[4,3-d][1,3]oxazol-6-yl]oxy]-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione 101713728 Drug sensitive (1S,2R,4R,6S,11R,12S,15R,18S,19R,20R,21S,23R,26R)-15-Hydroxy-11,18,21-trimethyl-5,17,24,28,29-pentaoxanonacyclo[17.9.1.11,20.02,12.04,6.06,11.015,19.018,23.021,26]triacont-8-ene-10,16,25,30-tetrone 101528280 Drug sensitive Erigerol 101318126 Drug sensitive [(1S,2S,4Z,8Z,12R,13S)-12-Hydroxy-4,8,12-trimethyl-16-methylidene-15-oxo-14-oxabicyclo[11.3.1]heptadeca-4,8-dien-2-yl] acetate 100921072 Drug sensitive Tocladesine 100299 Drug sensitive (1R,2E,6R,10E,11aS,13S,14aR)-6-(2-(benzyloxy)ethyl)-1,13-dihydroxy-6,7,8,9,12,13,14,14a-octahydro-1H-cyclopenta[f][1]oxacyclotridecin-4(11aH)-one - Drug resistant 2,3-dihydro-1,2-syn-3-[phenylseleno]brefeldin a - Drug resistant 9-methoxy-5-hydroxycamptothecin - Drug resistant tp4ek - Drug resistant (Z)-N-phenyl-3-(3,4,5-trimethoxystyryl)pyridin-2-amine - Drug sensitive 1,2-naphthoquinone, 3,7-dimethyl- - Drug sensitive 1h-benzimidazole, 5,5'-dithiobis[2-(trifluoromethyl)- (9ci) - Drug sensitive 2-[(3,4-dicloro)anilino]-3-phenyl-5,7-diamino quinoxaline - Drug sensitive 3',4',5'-trimethoxy-3-hydroxy flavone - Drug sensitive 4-(2-pyridinyl)-5h-1,2,3-dithiazole-5-thione - Drug sensitive 4-[3-(3,4-dihydro-1H-isoquinolin-2-yl)prop-1-en-2-yl]-N-pyrazin-2-ylbenzamide - Drug sensitive 4-quinazolone, 7-amino-3-(4-methoxyphenyl)-, hydrate - Drug sensitive 5.alpha.,25d-spirostan-3.beta.-ol glycoside - Drug sensitive 9h-quino[4,3,2-de][1,10]phenanthrolin-9-one, 5-methoxy- - Drug sensitive acetamide, n-(2-mercaptoethyl)-, benzoate (6ci, 7ci) - Drug sensitive b676297k277 3',4'-deoxypsorospermin 3',4'-chlorohydrin - Drug sensitive benzo[1,2-c:4,5-c']dipyrrole-1,3,5,7(2h,6h)-tetraimine - Drug sensitive benzofurazan, 4-nitro-7-(2-pyridinylthio)-, n-oxide - Drug sensitive bersaldegenin 1,3,5-orthoacetate - Drug sensitive cis-2-hydroxymethyl-4-(5'-bromocytosin-1'-yl)-1,3-dioxolane - Drug sensitive furan-2(3h)-one, 5-(4-methylphenyl)-3,3-diphenyl- - Drug sensitive isoflavone, 5,7-dihydroxy-4'-nitro- - Drug sensitive mercury, tetrakis(acetato)(2,3,4,5-thiophenetetrayl)tetra- - Drug sensitive n,n'-bis(oxydiethylene)thiocarbamoylsulfenamide - Drug sensitive phenol, 4,4'-(5,5'-biisoxazole-3,3'-diyl)bis- - Drug sensitive propan-1-one, 2,3-dichloro-1,3-bis(4-methylphenyl)- - Drug sensitive propanedinitrile, [(3,5-dibromo-2-ethoxyphenyl)methylene]- - Drug sensitive (Z)-3-((2-(4-(trifluoromethyl)phenyl)-3H-benzo[d]imidazol-5-yl)methylene)indolin-2-one - Drug sensitive [bis(aminomethyl)diethylsilane]dichloroplatinum (ii) - Drug sensitive 7-propanoyltaxol - Drug sensitive Aminopterin Derivative - Drug sensitive Annamycin Liposomal - Drug sensitive antineoplastic-d665839 - Drug sensitive Camptothecin Derivative - Drug sensitive Carboxyphthalatoplatinum - Drug sensitive chlorobis(4-ethyltropolonato)bismuth(iii) - Drug sensitive CI-921: amsacrine derivative - Drug sensitive Indenoisoquinoline derivative - Drug sensitive insulin-methotrexate conjugate - Drug sensitive merophan - Drug sensitive mitaplatin - Drug sensitive n-myristoyl-(s)-phenylalaninal diethylcetal - Drug sensitive organosulfur compound - Drug sensitive trimethyl(phenylthio)stannane - Drug sensitive

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-519e-3p	Alocrest 60780 Drug interaction    RC00005536 5-Fluorouracil 3385 Drug interaction    RC00005535 cis-Diaminedichloroplatinum 2767 Drug interaction    RC00005534 Tamoxifen 2733526 Drug interaction    RC00005537

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	FAM169B	6-Amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide       9956222 Benzamide, N-[4-[2-ethyl-4-(3-methylphenyl)-5-thiazolyl]-2-pyridinyl]-       9952773 1,2-Ethanediamine, N-(1,8-dimethylimidazo(1,2-a)quinoxalin-4-yl)-, monohydrochloride       9926054 Tivozanib       9911830 Zibotentan       9910224 5-(4-Fluorophenyl)-2-ureidothiophene-3-carboxamide       9903786 PI-103       9884685 2-Methoxy-N-[(2E)-3-[4-[[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]phenyl]amino]-6-quinazolinyl]-2-propen-1-yl]acetamide       9874913 Osi-930       9868037 Casuarine       9859098 2-(4-(Benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-imidazol-5-yl)-6-methylpyridine       9858940 Midostaurin       9829523 9H-Purine, 9-butyl-6-(methylthio)-       96530 Naphtho[1,2-d]thiazol-2-amine       94880 Acetic acid, [(aminoiminomethyl)thio]-       81899 (E)-1-(2-Hydroxyphenyl)-3-((1R,4R)-5-(pyridin-2-yl)-2,5-diazabicyclo[2.2.1]heptan-2-yl)prop-2-en-1-one       78243717 4,4'-Dithiodimorpholine       7648 N-[(1S,4S,7R,11S,14S,17S,20R,24S)-2,4,12,15,17,25-Hexamethyl-3,6,10,13,16,19,23,26-octaoxo-11,24-di(propan-2-yl)-20-(quinoxaline-2-carbonylamino)-9,22-dioxa-28,29-dithia-2,5,12,15,18,25-hexazabicyclo[12.12.4]triacontan-7-yl]quinoxaline-2-carboxamide       72534 2-Methoxy-N-(3-Methyl-2-Oxo-1,2,3,4-Tetrahydroquinazolin-6-Yl)benzenesulfonamide       71271629 N-(3-Methylphenyl)-4-pyridin-4-yl-1,3-thiazol-2-amine       704473 (S)-N-Hydroxy-4-(3-methyl-2-phenylbutanamido)benzamide       6918848 Belinostat       6918638 Daporinad       6914657 N-(5-(4-Chloro-3-(N-(2-hydroxyethyl)sulfamoyl)phenyl)-4-methylthiazol-2-yl)acetamide       6852167 3-Hydroxy-3'-nitro-2-naphthanilide       67277 Asn-Gln-Trp-Ala-Val-Gly-(D)Phe-Leu-Met-NH2       6711308 AICA ribonucleotide       65110 Tanespimycin       6505803 Ispinesib mesylate       6450816 Axitinib       6450551 Hygrophylline       6449975 Pelitinib       6445562 Dacinostat       6445533 4-(N-Hydroxyacetamido)stilbene       6433723 Cytarabine       6253 Gemcitabine       60750 Mitomycin       5746 Dimethyloxalylglycine       560326 Austocystin D       5470400 Mito-tempol       54613387 Sulfoquinovoside       54607989 Iridogermanal       5458843 Cristatic acid       5458761 3-[[2-[2-[2-[[(2S,3R)-2-[[(3S,4R)-4-[[(2S,3R)-2-[[6-Amino-2-[(1S)-3-amino-1-[[(2S)-2,3-diamino-3-oxopropyl]amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[3-[4-carbamoyloxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxypentanoyl]amino]-3-hydroxybutanoyl]amino]-2-(5-amino-3,4-dihydroxy-6-methyloxan-2-yl)oxy-1-hydroxyethyl]-1,3-thiazol-4-yl]-1,3-thiazole-4-carbonyl]amino]propyl-dimethylsulfanium;chloride;trihydrochloride       5458649 Temozolomide       5394 Senecionine N-oxide       5380876 Bleomycin a2       5360373 Anthramycin methyl ether       5351221 N-[4-[(4-Ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide       53340664 Palbociclib       5330286 N-[4-[(4-Ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[(E)-2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-5-yl)ethenyl]-4-methylbenzamide       53302361 Bosutinib       5328940 Vinorelbine       5311497 Vorinostat       5311 Isotretinoin       5282379 Bis(2-hydroxy-1-naphthyl) disulfide       521106 Semustine       5198 6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide       5113032 Alsterpaullone       5005498 Tubastatin A       49850262 Alectinib       49806720 Shikonin       479503 2-[(4s)-6-(4-Chlorophenyl)-8-Methoxy-1-Methyl-4h-[1,2,4]triazolo[4,3-A][1,4]benzodiazepin-4-Yl]-N-Ethylacetamide       46943432 (S)-(+)-Tert-Butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate       46907787 3-(4-(4-(2-(3-((Dimethylamino)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)-1-ethyl-1H-pyrazol-3-yl)phenyl)-1,1-dimethylurea       46885626 Avagacestat       46883536 Hexyl diethylcarbamo(dithioperoxo)thioate       46700805 Cyclohexyl diethylcarbamo(dithioperoxo)thioate       46197114 N-(6,6-Dimethyl-5-(1-methylpiperidine-4-carbonyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)-3-methylbutanamide       46191454 N-(2,2,2-Trifluoroethyl)-N-{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}benzenesulfonamide       447912 Okadaic acid       446512 1-(6,7-Dimethoxyquinazolin-4-yl)-3-(pyridin-2-yl)-1H-1,2,4-triazol-5-amine       44551660 Refametinib       44182295 Pyrodelphinine       431677 Foretinib       42642645 Benzofurazan, 4-(4-methyl-1-piperazinyl)-7-nitro-, 3-oxide       42640 Janus Red B       407803 4-(3-Carboxy-quinoxalin-2-yl)-oxyphenylacetyl acid       405748 Funkiosid H       401296 Roserine       395426 4-Carbamoyl-1h-imidazol-5-yl thiocyanate       388844 Ethyl-diphenyl-(2-phenylethynyl)phosphanium;iodide       386463 2(3H)-Furanone, dihydro-3-(3,4,5-trimethoxybenzyl)-4-veratryl-, trans-       384878 2,6-Dibromo-4-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol       3796 Sporanox       3793 N-(2-(3,5-Dimethoxyphenyl)-1-methylethyl)acetamide       378442 2-Bromo-1,4,8-trimethoxy-6-methylnaphthalene       378441 3-Formyl-8,8-dimethylbicyclo[3.2.1]octan-2-one       376778 8-Hydroxybicyclo[3.3.1]non-6-en-3-one       376749 Nickel meso formyl etioporphyrin       367720 Etoposide       36462 1,2,4,5-Tetrazine, 3,6-bis(1-azetidinyl)-       362170 5-Fluorouracil       3385 Ehretinine       336435 Embelin       3218 Doxorubicin       31703 Cetalkonium chloride       31202 Elesclomol       300471 AT 116, benzylamine salt       282523 Tamoxifen       2733526 1-(1,3-Dithiolan-2-yl)-4-trityloxybutane-2,3-diol       265955 1-(2-Chloroethyl)-3-(2,6-dioxo-3-piperidyl)-1-nitrosourea       26328 [5-[2,4-Bis((3S)-3-methylmorpholin-4-yl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl]methanol       25262965 2-(4-Methyl-1,4-diazepan-1-yl)-N-((5-methylpyrazin-2-yl)methyl)-5-oxo-5H-benzo[4,5]thiazolo[3,2-a][1,8]naphthyridine-6-carboxamide       25257557 4-[3-Fluoro-5-(4-morpholinyl)phenyl]-N-[4-[3-(4-morpholinyl)-1,2,4-triazol-1-yl]phenyl]-2-pyrimidinamine       25222038 Omipalisib       25167777 Ruxolitinib       25126798 Cabozantinib       25102847 2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid       25022668 Navitoclax       24978538 Tert-Butyl (4-(3-((7-(hydroxyamino)-7-oxoheptyl)carbamoyl)isoxazol-5-yl)phenyl)carbamate       24951314 Quizartinib       24889392 Ponatinib       24826799 Vismodegib       24776445 4-(6,6-Dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)-2-((1r,4r)-4-hydroxycyclohexylamino)benzamide       24772860 Cudc-101       24756910 Arenaemycin E       24199350 Vincaleukoblastine       241903 Menisperine iodide       24189461 Olaparib       23725625 Sodium 4-(4-(2-hydroxynaphthalenylazo)phenylazo)benzenesulphonate       22907 Nutlin-3       216345 Lenalidomide       216326 Aplysinamisine-III       197606 5-Benzyloxybenzylbarbituric acid       192294 Pigment orange 5       18981 Pictilisib       17755052 Adiantifoline       167937 4-Methyl-3-(1-methyl-6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino)-N-(3-(trifluoromethyl)phenyl)benzamide       16747388 Gsk-690693       16725726 Fedratinib       16722836 Obatoclax mesylate       16681698 3-[(1-Methyl-3-indolyl)methylidene]-1H-pyrrolo[3,2-b]pyridin-2-one       16219401 N-(3-{[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl]oxy}phenyl)-4-[2-(morpholin-4-yl)ethoxy]benzamide       16095342 Tipifarnib       159324 Methdilazine       14677 1-(Tert-Butyl)-3-(2-((4-(diethylamino)butyl)amino)-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl)urea       1401 Astrazon Orange R       135747272 (Z)-3-((3-((Dimethylamino)methyl)phenylamino)(phenyl)methylene)-N,N-dimethyl-2-oxoindoline-6-carboxamide       135659062 Talazoparib       135565082 Luminespib       135539077 Pac-1       135421197 (5Z)-5-(Quinolin-6-ylmethylidene)-2-[(thiophen-2-ylmethyl)amino]-1,3-thiazol-4(5H)-one       135400873 Osi-027       135398516 Akt inhibitor VIII       135398501 Abiraterone       132971 Methotrexate       126941 Lestaurtinib       126565 Gefitinib       123631 Dactolisib       11977753 Veliparib       11960529 BAY 61-3606 dihydrochloride       11784504 N-[3-[[5-Bromo-4-[[2-(1H-imidazol-5-YL)ethyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide       11754511 PF-00562271 free base       11713159 Trametinib       11707110 4,4'-(6-(2-(Difluoromethyl)-1H-benzo[d]imidazol-1-yl)-1,3,5-triazine-2,4-diyl)dimorpholine       11647372 Idelalisib       11625818 5-(3-Methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine       11617559 Benzamide, 4-((1R)-1-aminoethyl)-N-1H-pyrrolo(2,3-b)pyridin-4-yl-, hydrochloride (1:1)       11507964 (S)-N-((S)-1-Cyclohexyl-2-oxo-2-((3aR,7aS)-6-phenethyloctahydro-1H-pyrrolo[2,3-c]pyridin-1-yl)ethyl)-2-(methylamino)propanamide       11503417 5-(2-Phenylpyrazolo[1,5-A]pyridin-3-YL)-1H-pyrazolo[3,4-C]pyridazin-3-amine       11493598 Linifanib       11485656 Bafetinib       11387605 N-(6-Fluoro-1H-indazol-5-yl)-6-methyl-2-oxo-4-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1H-pyridine-5-carboxamide       11373846 4-(2,6-Dichlorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamide       11338033 8-(4-Dibenzothienyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one       11327430 Pararosaniline hydrochloride       11292 Amuvatinib       11282283 3-(4-Amino-3-(3-chloro-4-fluorophenyl)thieno[3,2-c]pyridin-7-yl)benzenesulfonamide       11281930 Sepantronium bromide       11178236 (S)-5-(3-Fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide       11152667 7-Ethyl-10-hydroxycamptothecin       104842 VX-702       10341154 Afatinib       10184653 N-(3-{[5-Iodo-4-({3-[(Thiophen-2-Ylcarbonyl)amino]propyl}amino)pyrimidin-2-Yl]amino}phenyl)pyrrolidine-1-Carboxamide       10077147 Masitinib       10074640 PDK1 inhibitor AR-12       10027278 2-[(3,4-dimethoxy)anilino]-3-phenyl-5,7-diaminoquinoxaline       - Basic Fuchsin       - Bleomycin (50 uM)       - Cisplatin       - ent-9a,13-dihydroxy-16,17-epoxy-kauran-19-oic acid       - Genentech Cpd 10       - ICL1100013       - indolo[3,4-d]benzazepin-6(5h)-one, 9-cyano-7,12-dihydro-       - JW-7-24-1       - KIN001-244       - KIN001-260       - KIN001-266       - KIN001-270       - MPS-1-IN-1       - NPK76-II-72-1       - Nutlin-3a (-)       - oil red b       - protein toxin c 10 - mw approx. 6700       - QL-X-138       - QL-XI-92       - QL-XII-47       - SB52334       - THZ-2-102-1       - TL-1-85       - TL-2-105       - triacetyl 13,14,15-isocrambescidin 800 hydrochloride       - Vinorelbine       - VNLG/124       - WZ3105       - XMD13-2       - XMD14-99       - XMD15-27       - (z)3,4,5-trimethoxystilbene       -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-519e-3p
Interactor2: FAM169B

Evidence Support:

Weak-Evidence	RNA-Seq
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	31570108	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	ARPE-19 human RPE cells	Interactor2 expression	None
Description	Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).