Detail Information

Basic Information:


  VIRBase ID:  

HHID00006423

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-519e-3p:           ZSCAN30:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-519e-3p ZSCAN30
miRBase
Accession/Entrez ID		 MIMAT0002829 100101467
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - ZNF-WYM//ZNF397OS//ZNF917

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-519e-3p
rs1320260913 chr19:53680012    T/TA
rs748109530 chr19:53680008    G/A
rs756692397 chr19:53679994    T/C
rs762638742 chr19:53679970    CTTTCTGTTTGAAAGAAAACAAAGTGCCTCCTTTTAGAGTG/C
rs778834695 chr19:53679997    C/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR ZSCAN30
chr18:32843093(-) A-I      NonSyn:Stp->Trp
chr18:32835182(-) A-I      intronic
chr18:32837614(-) A-I      intronic
chr18:32836902(-) A-I      intronic
chr18:32839169(-) A-I      intronic
chr18:32839302(-) A-I      intronic
chr18:32839332(-) A-I      intronic
chr18:32839267(-) A-I      intronic
chr18:32839334(-) A-I      intronic
chr18:32838591(-) A-I      intronic
chr18:32837612(-) A-I      intronic
chr18:32839324(-) A-I      intronic
chr18:32839312(-) A-I      intronic
chr18:32836958(-) A-I      intronic
chr18:32837607(-) A-I      intronic
chr18:32836953(-) A-I      intronic
chr18:32835311(-) A-I      intronic
chr18:32836401(-) A-I      intronic
chr18:32836320(-) A-I      intronic
chr18:32836287(-) A-I      intronic
chr18:32843182(-) A-I      Syn:Pro->Pro
chr18:32839362(-) A-I      intronic
chr18:32836278(-) A-I      intronic
chr18:32836265(-) A-I      intronic
chr18:32839325(-) A-I      intronic
chr18:32839363(-) A-I      intronic
chr18:32835298(-) A-I      intronic
chr18:32835236(-) A-I      intronic
chr18:32835185(-) A-I      intronic
chr18:32835183(-) A-I      intronic
chr18:32843170(-) A-I      Syn:Ala->Ala
chr18:32835225(-) A-I      intronic
chr18:32839327(-) A-I      intronic
chr18:32839416(-) A-I      intronic
chr18:32839386(-) A-I      intronic
chr18:32839349(-) A-I      intronic
chr18:32839329(-) A-I      intronic
chr18:32839288(-) A-I      intronic
chr18:32839326(-) A-I      intronic
chr18:32839323(-) A-I      intronic
chr18:32839320(-) A-I      intronic
chr18:32839294(-) A-I      intronic
chr18:32839411(-) A-I      intronic
chr18:32839271(-) A-I      intronic
chr18:32839248(-) A-I      intronic
chr18:32839246(-) A-I      intronic
chr18:32839208(-) A-I      intronic
chr18:32839191(-) A-I      intronic
chr18:32836403(-) A-I      intronic
chr18:32836377(-) A-I      intronic
chr18:32836358(-) A-I      intronic
chr18:32836277(-) A-I      intronic
chr18:32836332(-) A-I      intronic
chr18:32847000(-) A-I      intronic
chr18:32847064(-) A-I      intronic
chr18:32852245(-) A-I      intronic
chr18:32846998(-) A-I      intronic
chr18:32846997(-) A-I      intronic
chr18:32843123(-) A-I      NonSyn:Lys->Arg
chr18:32843189(-) A-I      NonSyn:Tyr->Cys
chr18:32838649(-) A-I      intronic
chr18:32838579(-) A-I      intronic
chr18:32839253(-) A-I      intronic
chr18:32836967(-) A-I      intronic
chr18:32839333(-) A-I      intronic
chr18:32852582(-) A-I      intronic
chr18:32839338(-) A-I      intronic
chr18:32839417(-) A-I      intronic
chr18:32852456(-) A-I      intronic
chr18:32838686(-) A-I      intronic
chr18:32836413(-) A-I      intronic
chr18:32836853(-) A-I      intronic
chr18:32839316(-) A-I      intronic
chr18:32836279(-) A-I      intronic
chr18:32838774(-) A-I      intronic
chr18:32839331(-) A-I      intronic
chr18:32836866(-) A-I      intronic
chr18:32839402(-) A-I      intronic
chr18:32839403(-) A-I      intronic
chr18:32838629(-) A-I      intronic
chr18:32839228(-) A-I      intronic
chr18:32836442(-) A-I      intronic
chr18:32852408(-) A-I      intronic
chr18:32838734(-) A-I      intronic
chr18:32860158(-) A-I      intronic
chr18:32843089(-) A-I      intronic
chr18:32850634(-) A-I      intronic
chr18:32838593(-) A-I      intronic
chr18:32839180(-) A-I      intronic
chr18:32839232(-) A-I      intronic
chr18:32836319(-) A-I      intronic
chr18:32839245(-) A-I      intronic
chr18:32836509(-) A-I      intronic
chr18:32839223(-) A-I      intronic
chr18:32836361(-) A-I      intronic
chr18:32843122(-) A-I      Syn:Lys->Lys
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED ZSCAN30
chr18:32835180(-) A-I intron -    15258596
chr18:32835189(-) A-I intron -    15258596
chr18:32835190(-) A-I intron -    15258596
chr18:32835239(-) A-I intron -    15258596
chr18:32839296(-) A-I intron -    22327324
chr18:32839390(-) A-I intron -    22327324
chr18:32839403(-) A-I intron -    22327324
chr18:32843089(-) A-I intron -    22327324
chr18:32835092(-) A-G intron -    22484847
chr18:32835095(-) A-G intron -    22484847
chr18:32835190(-) A-G intron -    22484847
chr18:32835291(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ZSCAN30
chr18:32831585-32831586(-) m6A 3'UTR       27773535
chr18:32833159-32833160(-) m6A 3'UTR//exon       24981863//27773535//22608085
chr18:32833283-32833284(-) m6A 3'UTR//exon       24284625//24981863//27773535//22608085
chr18:32833321-32833322(-) m6A 3'UTR//exon       24284625//24981863//28052920//27773535//27371828//22575960//22608085
chr18:32833355-32833356(-) m6A 3'UTR//exon       24284625//24981863//28052920//27773535//27371828//22575960//22608085
chr18:32833430-32833431(-) m6A CDS//exon       24284625//25456834//24981863//27773535//27371828//22608085
chr18:32833469-32833470(-) m6A CDS//exon       24284625//24981863//27773535//27371828//22608085
chr18:32833581-32833582(-) m6A CDS//exon       24284625//24981863//27773535//22608085
chr18:32833608-32833609(-) m6A CDS//exon       24284625//24981863//27773535//22608085
chr18:32833833-32833834(-) m6A CDS//exon       24284625//25456834//24981863//27773535//22608085
chr18:32833860-32833861(-) m6A CDS//exon       24284625//25456834//24981863//27773535//27371828//22608085
chr18:32833870-32833871(-) m6A CDS//exon       24284625//25456834//24981863//27773535//27371828//22608085
chr18:32833917-32833918(-) m6A CDS//exon       24284625//25456834//24981863//28052920//27773535//27371828//22608085
chr18:32833944-32833945(-) m6A CDS//exon       24284625//25456834//24981863//28052920//27773535//27371828//22608085
chr18:32834091-32834092(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085
chr18:32834137-32834138(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085
chr18:32834164-32834165(-) m6A CDS//exon       24284625//25456834//24981863//27773535//27371828//27773536//22608085
chr18:32834200-32834201(-) m6A CDS//exon       24284625//25456834//24981863//27773535//27371828//27773536//22608085
chr18:32834243-32834244(-) m6A CDS//exon       24284625//25456834//24981863//27773535//27371828//27773536//22608085
chr18:32834256-32834257(-) m6A CDS//exon       24284625//25456834//24981863//27773535//27371828//27773536//22608085
chr18:32840618-32840619(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr18:32840631-32840632(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr18:32840637-32840638(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr18:32840643-32840644(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr18:32840670-32840671(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr18:32840689-32840690(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr18:32840695-32840696(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr18:32840774-32840775(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr18:32840791-32840792(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr18:32840898-32840899(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr18:32840942-32840943(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr18:32840949-32840950(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr18:32840962-32840963(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr18:32840969-32840970(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr18:32840980-32840981(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr18:32841015-32841016(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr18:32841021-32841022(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr18:32841043-32841044(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr18:32841091-32841092(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr18:32841102-32841103(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr18:32841135-32841136(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr18:32841160-32841161(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr18:32841169-32841170(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr18:32841177-32841178(-) m6A 3'UTR//intron       24981863//27773535
chr18:32841181-32841182(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr18:32841203-32841204(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr18:32841265-32841266(-) m6A 3'UTR//intron       24284625//27773535//22608085
chr18:32841284-32841285(-) m6A 3'UTR//intron       24284625//27773535//22608085
chr18:32841367-32841368(-) m6A 3'UTR//intron       27773535//22608085
chr18:32841458-32841459(-) m6A 3'UTR//intron       24981863//27773535
chr18:32841470-32841471(-) m6A 3'UTR//intron       24981863//27773535
chr18:32841476-32841477(-) m6A 3'UTR//intron       24981863//27773535
chr18:32841502-32841503(-) m6A 3'UTR//intron       24981863//27773535
chr18:32841509-32841510(-) m6A 3'UTR//intron       24981863//27773535
chr18:32841601-32841602(-) m6A 3'UTR//intron       27773535
chr18:32841617-32841618(-) m6A 3'UTR//intron       27773535
chr18:32841628-32841629(-) m6A 3'UTR//intron       27773535
chr18:32842350-32842351(-) m6A 3'UTR//intron       22608085
chr18:32842395-32842396(-) m6A 3'UTR//intron       24981863//22608085
chr18:32842421-32842422(-) m6A 3'UTR//intron       24981863//22608085
chr18:32842516-32842517(-) m6A 3'UTR//intron       25456834//24981863//27773535//22608085
chr18:32842526-32842527(-) m6A 3'UTR//intron       25456834//24981863//27773535//22608085
chr18:32842539-32842540(-) m6A 3'UTR//intron       24284625//25456834//24981863//27773535//27371828//22608085
chr18:32842583-32842584(-) m6A 3'UTR//intron       24284625//25456834//24981863//27773535//27371828//27773536//22608085
chr18:32842622-32842623(-) m6A 3'UTR//intron       24284625//25456834//24981863//27773535//27371828//27773536//22608085
chr18:32842686-32842687(-) m6A 3'UTR//intron       24284625//25456834//27371828//27773536//22608085
chr18:32842810-32842811(-) m6A 3'UTR//intron       27773535//22608085
chr18:32842825-32842826(-) m6A 3'UTR//intron       27773535//22608085
chr18:32842879-32842880(-) m6A 3'UTR//intron       27773535//22608085
chr18:32842937-32842938(-) m6A 3'UTR//intron       27773535
chr18:32842954-32842955(-) m6A 3'UTR//intron       22608085
chr18:32842996-32842997(-) m6A 3'UTR//intron       22608085
chr18:32843619-32843620(-) m6A 3'UTR//CDS//intron       27773536
chr18:32843929-32843930(-) m6A CDS//intron       27773535//27773536
chr18:32844197-32844198(-) m6A CDS//intron       24284625//25456834//24981863//27773535//27371828//22608085
chr18:32844215-32844216(-) m6A CDS//intron       24284625//25456834//24981863//27773535//27371828//22608085
chr18:32844221-32844222(-) m6A CDS//intron       24284625//25456834//24981863//27773535//27371828//22608085
chr18:32844262-32844263(-) m6A CDS//intron       24284625//25456834//24981863//27773535//27371828//22608085
chr18:32844271-32844272(-) m6A CDS//intron       24284625//25456834//24981863//27773535//27371828//22608085
chr18:32844331-32844332(-) m6A 5'UTR//intron       24284625//25456834//24981863//27773535//22608085
chr18:32863388-32863389(-) m6A intron       24981863//22608085
chr18:32863531-32863532(-) m6A intron       -
chr18:32863725-32863726(-) m6A intron       24284625//25456834//24981863//27773535//27371828//22608085
chr18:32863793-32863794(-) m6A intron       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr18:32863804-32863805(-) m6A intron       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr18:32863842-32863843(-) m6A intron       24284625//25456834//24981863//27773535//27371828//22608085
chr18:32863849-32863850(-) m6A intron       24284625//25456834//24981863//27773535//27371828//22608085
chr18:32863855-32863856(-) m6A intron       24284625//25456834//24981863//27773535//27371828//22608085
chr18:32864003-32864004(-) m6A intron       24284625//24209618//25456834//27371828//22608085
chr18:32864071-32864072(-) m6A intron       24284625//24209618//25456834//24981863//27371828//27773536//22608085
chr18:32864082-32864083(-) m6A intron       24284625//24209618//25456834//24981863//27371828//27773536//22608085
chr18:32864142-32864143(-) m6A intron       24284625//24209618//25456834//24981863//28052920//27371828//27773536//22608085
chr18:32864155-32864156(-) m6A intron       24284625//24209618//25456834//24981863//28052920//27371828//27773536//22608085
chr18:32864165-32864166(-) m6A intron       24284625//24209618//25456834//24981863//28052920//27371828//27773536//22608085
chr18:32864214-32864215(-) m6A intron       24284625//24209618//25456834//24981863//27371828//22608085
chr18:32864236-32864237(-) m6A intron       24284625//24209618//25456834//24981863//27371828//22608085
chr18:32864257-32864258(-) m6A intron       24284625//24209618//25456834//24981863//27371828//22608085
chr18:32864376-32864377(-) m6A intron       24284625//24209618//25456834//24981863//27371828//22608085
chr18:32864445-32864446(-) m6A intron       24284625//24209618//25456834//24981863//27371828//22608085
chr18:32864462-32864463(-) m6A intron       24284625//24209618//25456834//24981863//27371828//22608085
chr18:32864688-32864689(-) m6A intron       22608085
chr18:32864816-32864817(-) m6A intron       25456834//27371828//27773536//22608085
chr18:32864881-32864882(-) m6A intron       25456834//27371828//27773536//22608085
chr18:32864988-32864989(-) m6A intron       25456834
chr18:32865077-32865078(-) m6A intron       25456834

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-519e-3p
Exosome Brain tissue     23382797
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
ZSCAN30
Chromatin K562 cells     -
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus K562 cells     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function
ncDR hsa-miR-519e-3p
Iodine Green 9956454 Drug sensitive
2-(2,4-Difluorophenyl)-4,5,6,7-tetrafluoro-1H-isoindole-1,3(2H)-dione 9905583 Drug sensitive
Kahalalide F 9898671 Drug resistant
CID 9604911 9604911 Drug sensitive
Actinomycin X4357G methoxime 9573583 Drug sensitive
Indolo[2,1-b]quinazoline-6,12-dione 73549 Drug sensitive
Venenatine 73061 Drug sensitive
Redoxal 72571 Drug sensitive
Piperidinium pentamethylenedithiocarbamate 72508 Drug sensitive
4-(2-Naphthylamino)phenol 7141 Drug sensitive
Tolonium chloride 7083 Drug sensitive
Sulbentine 67686 Drug sensitive
Reactive Blue 2 656725 Drug sensitive
(2R,3R,4S,5R)-2-(6-Benzylsulfanylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol 6477178 Drug sensitive
Vicenistatin 6438888 Drug sensitive
Verrucarin A 6326658 Drug sensitive
Deferoxamine hydrochloride 62880 Drug sensitive
Cytarabine 6253 Drug sensitive
Bizelesin 60794 Drug sensitive
Tributyrin 6050 Drug sensitive
Triethylenemelamine 5799 Drug sensitive
Teclothiazide potassium 56841138 Drug sensitive
(3beta)-3-((4-O-beta-D Glucopyranosyl-beta-D-xylopyranosyl)oxy)-14-hydroxy-19-oxocarda-4,20(22)-dienolide 56840951 Drug sensitive
Caracemide 54747 Drug sensitive
7Z-Plakortide H 5472712 Drug sensitive
Artelasticin 5471311 Drug sensitive
Antineoplastic-690266 5469577 Drug sensitive
3-Deazauridine 54684286 Drug sensitive
3,19-(4-Acetamido)benzylidineandrographolide 54612901 Drug sensitive
Herveline O 5459269 Drug sensitive
Betuletol 5459196 Drug sensitive
Cuspidatin C 5459164 Drug sensitive
Thiram 5455 Drug sensitive
Piritrexim isethionate 54368 Drug sensitive
(E)-1-(2,5-Dihydroxyphenyl)ethene-2-isonitrile 5388136 Drug sensitive
(1E,4E)-1,5-Dipyridin-3-ylpenta-1,4-dien-3-one 5382674 Drug sensitive
Crassin, acetate 5355441 Drug sensitive
Rozex 5353923 Drug sensitive
MX2 hydrochloride 5351347 Drug sensitive
Dihydro-5-azacytidine 5351280 Drug sensitive
7-(3-Methoxyphenyl)-N-(pyridin-4-ylmethylideneamino)-5H-pyrrolo[3,2-d]pyrimidin-4-amine 53239944 Drug sensitive
Vorinostat 5311 Drug sensitive
Improsulfan hydrochloride 5284401 Drug sensitive
Kekule 499328 Drug sensitive
Pyrimethamine 4993 Drug sensitive
10-Hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12-dodecahydro-1H-picene-4a-carboxylic acid 495604 Drug sensitive
Propyl gallate 4947 Drug resistant
1,4-Benzoquinone 4650 Drug sensitive
Melphalan 460612 Drug sensitive
Aclarubicin 451415 Drug sensitive
Ossirene 451379 Drug sensitive
Mycophenolic acid 446541 Drug sensitive
1-(4-(Benzyloxy)phenyl)-3-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl)phenyl)urea 44587530 Drug sensitive
Isopinnatal 44558939 Drug sensitive
Iproplatin 44214 Drug sensitive
Di-n-octyl-secalonsaure A 430141 Drug sensitive
S-(Dimethylarsino)-3-mercapto-1,2-propyl dibenzoate 406481 Drug sensitive
Aminopyrimidine-CH3 406278 Drug sensitive
Mechlorethamine 4033 Drug sensitive
Artelastin 399488 Drug sensitive
Cbz-[Lys3]-Didemnin B 398464 Drug resistant
Loratadine 3957 Drug sensitive
2,5-Bis(aziridin-1-yl)-3-(hydroxymethyl)-6-methylcyclohexa-2,5-diene-1,4-dione 394347 Drug sensitive
Sjg-136 393111 Drug sensitive
Leflunomide 3899 Drug sensitive
beta-Lapachone 3885 Drug sensitive
Lapachol 3884 Drug sensitive
Benzo[1,2-b:5,4-b']dithiophene-4,8-dione, 2-acetyl- 388028 Drug sensitive
3-(4-Fluorophenyl)-3-(4-hydroxy-2-methylphenyl)-2-benzofuran-1(3H)-one 387973 Drug resistant
1,3-Diphenyl-6-((triphenylphosphoranylidene)amino)-2,4(1H,3H)-pyrimidinedione 387460 Drug sensitive
Acetic acid,4,7,10-tetraazacyclododecane-1,7-diyl]bis 387352 Drug sensitive
L-LYS-L-p-NO2Phe-L-Ala-L-p-NO2PheNH2 386384 Drug sensitive
Stereoisomer of NSC 674066-O 384359 Drug sensitive
3-(4-Fluorophenyl)-3-(4-acetoxy-2-methylphenyl)phthalide 383342 Drug resistant
1-Azido-2-phenyl-3-phenalenone 381891 Drug sensitive
2-Acetyl-1,2-dihydroellipticine 376328 Drug resistant
Sanguilutine pseudobase 371258 Drug sensitive
1,2-Dimethyl-phenothiazone 369387 Drug sensitive
4-Nitro-6-(trifluoromethyl)-2,1,3-benzoselenadiazole 362897 Drug sensitive
Aplidazole C . TFA 362402 Drug sensitive
Predorine 333830 Drug sensitive
Rocaglamide 331783 Drug sensitive
Pinafide 327045 Drug sensitive
2,3-Dimethoxy-5-naphthalen-2-ylsulfanylcyclohexa-2,5-diene-1,4-dione 314728 Drug sensitive
Cytosine, 1beta-D-arabinofuranosyl-N(sup 4)-stearoyl- 304673 Drug sensitive
Flurocitabine 3034016 Drug sensitive
P-Ara-C 282479 Drug sensitive
Dichloroallyl lawsone 277767 Drug sensitive
6-Bromotoyocamycin 270861 Drug sensitive
2'-Deoxy-5-(trifluoromethyl)uridine 253083 Drug sensitive
2-(7-Aminotriazolo[4,5-d]pyrimidin-3-yl)-5-(hydroxymethyl)oxolane-3,4-diol 251928 Drug sensitive
2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-N-[2-(methylamino)ethyl]-1H-imidazo[4,5-c]pyridine-7-carboxamide 25023715 Drug resistant
9H-Purine, 6-(o-chlorobenzylthio)-9-(2-chloroethyl)- 246231 Drug sensitive
9H-Purine, 6-(benzylthio)-9-(2-chloroethyl)- 246230 Drug sensitive
Antimycin A3 245869 Drug sensitive
Prumycin HCl 24197905 Drug resistant
Cinerubin A hcl 24196924 Drug sensitive
9H-Purine, 2-amino-6-(o-chlorobenzylthio)-9-propyl- 239486 Drug sensitive
Spongiaquinone 23424796 Drug resistant
[(1S,2Z,4R,8R,9R,11R,13S)-13-Acetyloxy-1-hydroxy-2,11-dimethyl-7-methylidene-6-oxo-5,14-dioxatricyclo[9.2.1.04,8]tetradec-2-en-9-yl] 2-methylpropanoate 23255746 Drug sensitive
Amsacrine 2179 Drug sensitive
Pirarubicin hydrochloride 20846247 Drug sensitive
7,8-Dihydroxyflavone 1880 Drug sensitive
Sudan II 18386 Drug sensitive
4-Chloro-5-phenoxy-3H-1,2-dithiole-3-thione 16766044 Drug sensitive
Azaribine 16574 Drug sensitive
(2Z,9E,13Z,15E)-4',11-Dihydroxy-2,4',9-trimethylspiro[3-aza-1(2,4)-thiazolacyclohexadecaphanene-6,3'-[1,2]dithiolane]-9,13,15-triene-4,5',12-trione 2'-oxide 154730760 Drug sensitive
Methyl (3'R)-3,4',9',10-tetrahydroxy-3'-[(2S,4R,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-7'-methoxy-5',8',9-trioxospiro[3,4-dihydropyrano[4,3-g]chromene-2,2'-3H-benzo[f][1]benzofuran]-7-carboxylate 137326876 Drug sensitive
C8, Carbonyl prodigiosine 135540857 Drug sensitive
5-[(E)-[Amino(methyl)amino]azo]-1H-imidazole-4-carboxamide 135493930 Drug sensitive
Cysteine, S-[(4-aminocarbonyl-1H-imidazol-5-yl)azo]- 135493928 Drug sensitive
Emofolin sodium 135475347 Drug sensitive
8-Azahypoxanthine 135410720 Drug sensitive
Raltitrexed 135400182 Drug sensitive
DTIC-Dome 135398738 Drug sensitive
(2S,4S,5R)-20-De(1-hydroxypropyl)-6-demethyl-2,6-diethyl-5-hydroxy-20-(1-hydroxybutyl)lysocellin 124081057 Drug sensitive
p-Toluquinone 11122 Drug sensitive
Gentian violet 11057 Drug sensitive
Withajardin C 102469053 Drug sensitive
(7S,9S)-7-[[(3As,4S,7aS)-1-[[(3aS,4S,7aS)-4-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-2,3a,4,6,7,7a-hexahydropyrano[4,3-d][1,3]oxazol-1-yl]methyl]-4-methyl-2,3a,4,6,7,7a-hexahydropyrano[4,3-d][1,3]oxazol-6-yl]oxy]-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione 101713728 Drug sensitive
(1S,2R,4R,6S,11R,12S,15R,18S,19R,20R,21S,23R,26R)-15-Hydroxy-11,18,21-trimethyl-5,17,24,28,29-pentaoxanonacyclo[17.9.1.11,20.02,12.04,6.06,11.015,19.018,23.021,26]triacont-8-ene-10,16,25,30-tetrone 101528280 Drug sensitive
Erigerol 101318126 Drug sensitive
[(1S,2S,4Z,8Z,12R,13S)-12-Hydroxy-4,8,12-trimethyl-16-methylidene-15-oxo-14-oxabicyclo[11.3.1]heptadeca-4,8-dien-2-yl] acetate 100921072 Drug sensitive
Tocladesine 100299 Drug sensitive
(1R,2E,6R,10E,11aS,13S,14aR)-6-(2-(benzyloxy)ethyl)-1,13-dihydroxy-6,7,8,9,12,13,14,14a-octahydro-1H-cyclopenta[f][1]oxacyclotridecin-4(11aH)-one - Drug resistant
2,3-dihydro-1,2-syn-3-[phenylseleno]brefeldin a - Drug resistant
9-methoxy-5-hydroxycamptothecin - Drug resistant
tp4ek - Drug resistant
(Z)-N-phenyl-3-(3,4,5-trimethoxystyryl)pyridin-2-amine - Drug sensitive
1,2-naphthoquinone, 3,7-dimethyl- - Drug sensitive
1h-benzimidazole, 5,5'-dithiobis[2-(trifluoromethyl)- (9ci) - Drug sensitive
2-[(3,4-dicloro)anilino]-3-phenyl-5,7-diamino quinoxaline - Drug sensitive
3',4',5'-trimethoxy-3-hydroxy flavone - Drug sensitive
4-(2-pyridinyl)-5h-1,2,3-dithiazole-5-thione - Drug sensitive
4-[3-(3,4-dihydro-1H-isoquinolin-2-yl)prop-1-en-2-yl]-N-pyrazin-2-ylbenzamide - Drug sensitive
4-quinazolone, 7-amino-3-(4-methoxyphenyl)-, hydrate - Drug sensitive
5.alpha.,25d-spirostan-3.beta.-ol glycoside - Drug sensitive
9h-quino[4,3,2-de][1,10]phenanthrolin-9-one, 5-methoxy- - Drug sensitive
acetamide, n-(2-mercaptoethyl)-, benzoate (6ci, 7ci) - Drug sensitive
b676297k277 3',4'-deoxypsorospermin 3',4'-chlorohydrin - Drug sensitive
benzo[1,2-c:4,5-c']dipyrrole-1,3,5,7(2h,6h)-tetraimine - Drug sensitive
benzofurazan, 4-nitro-7-(2-pyridinylthio)-, n-oxide - Drug sensitive
bersaldegenin 1,3,5-orthoacetate - Drug sensitive
cis-2-hydroxymethyl-4-(5'-bromocytosin-1'-yl)-1,3-dioxolane - Drug sensitive
furan-2(3h)-one, 5-(4-methylphenyl)-3,3-diphenyl- - Drug sensitive
isoflavone, 5,7-dihydroxy-4'-nitro- - Drug sensitive
mercury, tetrakis(acetato)(2,3,4,5-thiophenetetrayl)tetra- - Drug sensitive
n,n'-bis(oxydiethylene)thiocarbamoylsulfenamide - Drug sensitive
phenol, 4,4'-(5,5'-biisoxazole-3,3'-diyl)bis- - Drug sensitive
propan-1-one, 2,3-dichloro-1,3-bis(4-methylphenyl)- - Drug sensitive
propanedinitrile, [(3,5-dibromo-2-ethoxyphenyl)methylene]- - Drug sensitive
(Z)-3-((2-(4-(trifluoromethyl)phenyl)-3H-benzo[d]imidazol-5-yl)methylene)indolin-2-one - Drug sensitive
[bis(aminomethyl)diethylsilane]dichloroplatinum (ii) - Drug sensitive
7-propanoyltaxol - Drug sensitive
Aminopterin Derivative - Drug sensitive
Annamycin Liposomal - Drug sensitive
antineoplastic-d665839 - Drug sensitive
Camptothecin Derivative - Drug sensitive
Carboxyphthalatoplatinum - Drug sensitive
chlorobis(4-ethyltropolonato)bismuth(iii) - Drug sensitive
CI-921: amsacrine derivative - Drug sensitive
Indenoisoquinoline derivative - Drug sensitive
insulin-methotrexate conjugate - Drug sensitive
merophan - Drug sensitive
mitaplatin - Drug sensitive
n-myristoyl-(s)-phenylalaninal diethylcetal - Drug sensitive
organosulfur compound - Drug sensitive
trimethyl(phenylthio)stannane - Drug sensitive
Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-519e-3p
Alocrest 60780 Drug interaction    RC00005536
5-Fluorouracil 3385 Drug interaction    RC00005535
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00005534
Tamoxifen 2733526 Drug interaction    RC00005537

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-519e-3p
Interactor2: ZSCAN30

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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