Detail Information

Basic Information:


  VIRBase ID:  

HHID00006397

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-519e-3p:           SAMD12:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-519e-3p SAMD12
miRBase
Accession/Entrez ID		 MIMAT0002829 401474
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-519e-3p
rs1320260913 chr19:53680012    T/TA
rs748109530 chr19:53680008    G/A
rs756692397 chr19:53679994    T/C
rs762638742 chr19:53679970    CTTTCTGTTTGAAAGAAAACAAAGTGCCTCCTTTTAGAGTG/C
rs778834695 chr19:53679997    C/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SAMD12
chr8:119310610(-) A-I      intronic
chr8:119569063(-) A-I      intronic
chr8:119569095(-) A-I      intronic
chr8:119310540(-) A-I      intronic
chr8:119310530(-) A-I      intronic
chr8:119489501(-) A-I      intronic
chr8:119310502(-) A-I      intronic
chr8:119310490(-) A-I      intronic
chr8:119247578(-) A-I      intronic
chr8:119310450(-) A-I      intronic
chr8:119247573(-) A-I      intronic
chr8:119246906(-) A-I      intronic
chr8:119489500(-) A-I      intronic
chr8:119487431(-) A-I      intronic
chr8:119487426(-) A-I      intronic
chr8:119310377(-) A-I      intronic
chr8:119310358(-) A-I      intronic
chr8:119487396(-) A-I      intronic
chr8:119487311(-) A-I      intronic
chr8:119246757(-) A-I      intronic
chr8:119246781(-) A-I      intronic
chr8:119360448(-) A-I      intronic
chr8:119360418(-) A-I      intronic
chr8:119246786(-) A-I      intronic
chr8:119310327(-) A-I      intronic
chr8:119246868(-) A-I      intronic
chr8:119442850(-) A-I      intronic
chr8:119246887(-) A-I      intronic
chr8:119313091(-) A-I      intronic
chr8:119310285(-) A-I      intronic
chr8:119308374(-) A-I      intronic
chr8:119288093(-) A-I      intronic
chr8:119310286(-) A-I      intronic
chr8:119442794(-) A-I      intronic
chr8:119442775(-) A-I      intronic
chr8:119369671(-) A-I      intronic
chr8:119442766(-) A-I      intronic
chr8:119288946(-) A-I      intronic
chr8:119512999(-) A-I      intronic
chr8:119313081(-) A-I      intronic
chr8:119288947(-) A-I      intronic
chr8:119512828(-) A-I      intronic
chr8:119351412(-) A-I      intronic
chr8:119351436(-) A-I      intronic
chr8:119351444(-) A-I      intronic
chr8:119442717(-) A-I      intronic
chr8:119351486(-) A-I      intronic
chr8:119512429(-) A-I      intronic
chr8:119310657(-) A-I      intronic
chr8:119351555(-) A-I      intronic
chr8:119351563(-) A-I      intronic
chr8:119352864(-) A-I      intronic
chr8:119352925(-) A-I      intronic
chr8:119360775(-) A-I      intronic
chr8:119360795(-) A-I      intronic
chr8:119360821(-) A-I      intronic
chr8:119360870(-) A-I      intronic
chr8:119362174(-) A-I      intronic
chr8:119362243(-) A-I      intronic
chr8:119362256(-) A-I      intronic
chr8:119362267(-) A-I      intronic
chr8:119313092(-) A-I      intronic
chr8:119369650(-) A-I      intronic
chr8:119369609(-) A-I      intronic
chr8:119360460(-) A-I      intronic
chr8:119313098(-) A-I      intronic
chr8:119313107(-) A-I      intronic
chr8:119360454(-) A-I      intronic
chr8:119313145(-) A-I      intronic
chr8:119313222(-) A-I      intronic
chr8:119313223(-) A-I      intronic
chr8:119442091(-) A-I      intronic
chr8:119313276(-) A-I      intronic
chr8:119330754(-) A-I      intronic
chr8:119353792(-) A-I      intronic
chr8:119569593(-) A-I      intronic
chr8:119569602(-) A-I      intronic
chr8:119569605(-) A-I      intronic
chr8:119573946(-) A-I      intronic
chr8:119573949(-) A-I      intronic
chr8:119310643(-) A-I      intronic
chr8:119490126(-) A-I      intronic
chr8:119247698(-) A-I      intronic
chr8:119313039(-) A-I      intronic
chr8:119310639(-) A-I      intronic
chr8:119490063(-) A-I      intronic
chr8:119489509(-) A-I      intronic
chr8:119247677(-) A-I      intronic
chr8:119313036(-) A-I      intronic
chr8:119359375(-) A-I      intronic
chr8:119568947(-) A-I      intronic
chr8:119310637(-) A-I      intronic
chr8:119585502(-) A-I      intronic
chr8:119568959(-) A-I      intronic
chr8:119362245(-) A-I      intronic
chr8:119362163(-) A-I      intronic
chr8:119489508(-) A-I      intronic
chr8:119362132(-) A-I      intronic
chr8:119362123(-) A-I      intronic
chr8:119362108(-) A-I      intronic
chr8:119360467(-) A-I      intronic
chr8:119514059(-) A-I      intronic
chr8:119512420(-) A-I      intronic
chr8:119313074(-) A-I      intronic
chr8:119512403(-) A-I      intronic
chr8:119288945(-) A-I      intronic
chr8:119310650(-) A-I      intronic
chr8:119360444(-) A-I      intronic
chr8:119280970(-) A-I      intronic
chr8:119619679(-) A-I      intronic
chr8:119216947(-) A-I      intronic
chr8:119353000(-) A-I      intronic
chr8:119348073(-) A-I      intronic
chr8:119216917(-) A-I      intronic
chr8:119512386(-) A-I      intronic
chr8:119280897(-) A-I      intronic
chr8:119346991(-) A-I      intronic
chr8:119346868(-) A-I      intronic
chr8:119346867(-) A-I      intronic
chr8:119297069(-) A-I      intronic
chr8:119362284(-) A-I      intronic
chr8:119378895(-) A-I      intronic
chr8:119389423(-) A-I      intronic
chr8:119401771(-) A-I      intronic
chr8:119490142(-) A-I      intronic
chr8:119401830(-) A-I      intronic
chr8:119404389(-) A-I      intronic
chr8:119404423(-) A-I      intronic
chr8:119280819(-) A-I      intronic
chr8:119313046(-) A-I      intronic
chr8:119408008(-) A-I      intronic
chr8:119442070(-) A-I      intronic
chr8:119370327(-) A-I      intronic
chr8:119512950(-) A-I      intronic
chr8:119353006(-) A-I      intronic
chr8:119437680(-) A-I      intronic
chr8:119328529(-) A-I      intronic
chr8:119441953(-) A-I      intronic
chr8:119247547(-) A-I      intronic
chr8:119486899(-) A-I      intronic
chr8:119328517(-) A-I      intronic
chr8:119435297(-) A-I      intronic
chr8:119486898(-) A-I      intronic
chr8:119442893(-) A-I      intronic
chr8:119247629(-) A-I      intronic
chr8:119370378(-) A-I      intronic
chr8:119520305(-) A-I      intronic
chr8:119512933(-) A-I      intronic
chr8:119246783(-) A-I      intronic
chr8:119489593(-) A-I      intronic
chr8:119489594(-) A-I      intronic
chr8:119362272(-) A-I      intronic
chr8:119289032(-) A-I      intronic
chr8:119512800(-) A-I      intronic
chr8:119370298(-) A-I      intronic
chr8:119437732(-) A-I      intronic
chr8:119461836(-) A-I      intronic
chr8:119329111(-) A-I      intronic
chr8:119362285(-) A-I      intronic
chr8:119471370(-) A-I      intronic
chr8:119369614(-) A-I      intronic
chr8:119362255(-) A-I      intronic
chr8:119486370(-) A-I      intronic
chr8:119461465(-) A-I      intronic
chr8:119429458(-) A-I      intronic
chr8:119442827(-) A-I      intronic
chr8:119369653(-) A-I      intronic
chr8:119289139(-) A-I      intronic
chr8:119289049(-) A-I      intronic
chr8:119410526(-) A-I      intronic
chr8:119369677(-) A-I      intronic
chr8:119512857(-) A-I      intronic
chr8:119486821(-) A-I      intronic
chr8:119490132(-) A-I      intronic
chr8:119247676(-) A-I      intronic
chr8:119369745(-) A-I      intronic
chr8:119442119(-) A-I      intronic
chr8:119484362(-) A-I      intronic
chr8:119487286(-) A-I      intronic
chr8:119490018(-) A-I      intronic
chr8:119369633(-) A-I      intronic
chr8:119512455(-) A-I      intronic
chr8:119442858(-) A-I      intronic
chr8:119352868(-) A-I      intronic
chr8:119484404(-) A-I      intronic
chr8:119486757(-) A-I      intronic
chr8:119512554(-) A-I      intronic
chr8:119362164(-) A-I      intronic
chr8:119352994(-) A-I      intronic
chr8:119410307(-) A-I      intronic
chr8:119359321(-) A-I      intronic
chr8:119369568(-) A-I      intronic
chr8:119351401(-) A-I      intronic
chr8:119352945(-) A-I      intronic
chr8:119246855(-) A-I      intronic
chr8:119486338(-) A-I      intronic
chr8:119254249(-) A-I      intronic
chr8:119329166(-) A-I      intronic
chr8:119489365(-) A-I      intronic
chr8:119484378(-) A-I      intronic
chr8:119487243(-) A-I      intronic
chr8:119486907(-) A-I      intronic
chr8:119247632(-) A-I      intronic
chr8:119328539(-) A-I      intronic
chr8:119486905(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED SAMD12
chr8:119329168(-) A-I intron -    22327324
chr8:119461060(-) A-I intron -    21960545
chr8:119461083(-) A-I intron -    21960545
chr8:119569642(-) A-I intron -    21960545
chr8:119246714(-) A-G intron -    22484847
chr8:119246855(-) A-G intron -    22484847
chr8:119246936(-) A-G intron -    22484847
chr8:119246949(-) G-T intron -    22484847
chr8:119247629(-) A-G intron -    22484847
chr8:119247632(-) A-G intron -    22484847
chr8:119247676(-) A-G intron -    22484847
chr8:119289139(-) A-G intron -    22484847
chr8:119430811(-) T-C intron -    22484847
chr8:119435285(-) T-C intron -    22484847
chr8:119435297(-) A-G intron -    22484847
chr8:119441889(-) A-G intron -    22484847
chr8:119441950(-) A-G intron -    22484847
chr8:119442033(-) A-G intron -    22484847
chr8:119442119(-) A-G intron -    22484847
chr8:119442784(-) A-G intron -    22484847
chr8:119442827(-) A-G intron -    22484847
chr8:119442858(-) A-G intron -    22484847
chr8:119461465(-) A-G intron -    22484847
chr8:119486757(-) A-G intron -    22484847
chr8:119486907(-) A-G intron -    22484847
chr8:119487243(-) A-G intron -    22484847
chr8:119487260(-) A-G intron -    22484847
chr8:119487286(-) A-G intron -    22484847
chr8:119489594(-) A-G intron -    22484847
chr8:119490018(-) A-G intron -    22484847
chr8:119512554(-) A-G intron -    22484847
chr8:119512993(-) A-G intron -    22484847
chr8:119543170(-) A-T intron -    22484847
chr8:119310698(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SAMD12
chr8:119206129-119206130(-) m6A 3'UTR       27773535
chr8:119206147-119206148(-) m6A 3'UTR       27773535
chr8:119207104-119207105(-) m6A 3'UTR       24209618//27773535//22608085
chr8:119207184-119207185(-) m6A 3'UTR       24284625//24209618//27773535//22608085
chr8:119207202-119207203(-) m6A 3'UTR       24284625//24209618//27773535//22608085
chr8:119207257-119207258(-) m6A 3'UTR       24284625//24981863//27773535//22575960//22608085
chr8:119207280-119207281(-) m6A 3'UTR       24981863//27773535//22575960//22608085
chr8:119207303-119207304(-) m6A 3'UTR       24981863//27773535//22608085
chr8:119207393-119207394(-) m6A 3'UTR       24209618//24981863//27773535//22608085
chr8:119207471-119207472(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085
chr8:119207476-119207477(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085
chr8:119207499-119207500(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr8:119207509-119207510(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085
chr8:119207558-119207559(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085
chr8:119207588-119207589(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085
chr8:119207739-119207740(-) m6A 3'UTR       24209618//25456834//27773535//22608085
chr8:119207797-119207798(-) m6A 3'UTR       24209618//25456834//24981863//27773535//22608085
chr8:119207850-119207851(-) m6A 3'UTR       24209618//25456834//24981863//27773535//22608085
chr8:119207890-119207891(-) m6A 3'UTR       24209618//24981863//27773535//22608085
chr8:119207901-119207902(-) m6A 3'UTR       24209618//24981863//27773535//22608085
chr8:119207955-119207956(-) m6A 3'UTR       24209618//24981863//27773535//22608085
chr8:119207977-119207978(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085
chr8:119208133-119208134(-) m6A 3'UTR       24284625//24209618//22608085
chr8:119208156-119208157(-) m6A 3'UTR       24284625//24209618//22608085
chr8:119208193-119208194(-) m6A 3'UTR       24209618//22608085
chr8:119208212-119208213(-) m6A 3'UTR       -
chr8:119208269-119208270(-) m6A 3'UTR       24284625//25456834//27773536
chr8:119208494-119208495(-) m6A 3'UTR       27773535
chr8:119209228-119209229(-) m6A 3'UTR       -
chr8:119209300-119209301(-) m6A 3'UTR       27773535
chr8:119209705-119209706(-) m6A 3'UTR       24284625//27773535//22608085
chr8:119209839-119209840(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22608085
chr8:119209880-119209881(-) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085
chr8:119209904-119209905(-) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085
chr8:119209947-119209948(-) m6A 3'UTR       24209618//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-519e-3p
Exosome Brain tissue     23382797
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
SAMD12
Exosome Blood     -
Nucleus HeLa-S3 cells     -
Ribosome Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function
ncDR hsa-miR-519e-3p
Iodine Green 9956454 Drug sensitive
2-(2,4-Difluorophenyl)-4,5,6,7-tetrafluoro-1H-isoindole-1,3(2H)-dione 9905583 Drug sensitive
Kahalalide F 9898671 Drug resistant
CID 9604911 9604911 Drug sensitive
Actinomycin X4357G methoxime 9573583 Drug sensitive
Indolo[2,1-b]quinazoline-6,12-dione 73549 Drug sensitive
Venenatine 73061 Drug sensitive
Redoxal 72571 Drug sensitive
Piperidinium pentamethylenedithiocarbamate 72508 Drug sensitive
4-(2-Naphthylamino)phenol 7141 Drug sensitive
Tolonium chloride 7083 Drug sensitive
Sulbentine 67686 Drug sensitive
Reactive Blue 2 656725 Drug sensitive
(2R,3R,4S,5R)-2-(6-Benzylsulfanylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol 6477178 Drug sensitive
Vicenistatin 6438888 Drug sensitive
Verrucarin A 6326658 Drug sensitive
Deferoxamine hydrochloride 62880 Drug sensitive
Cytarabine 6253 Drug sensitive
Bizelesin 60794 Drug sensitive
Tributyrin 6050 Drug sensitive
Triethylenemelamine 5799 Drug sensitive
Teclothiazide potassium 56841138 Drug sensitive
(3beta)-3-((4-O-beta-D Glucopyranosyl-beta-D-xylopyranosyl)oxy)-14-hydroxy-19-oxocarda-4,20(22)-dienolide 56840951 Drug sensitive
Caracemide 54747 Drug sensitive
7Z-Plakortide H 5472712 Drug sensitive
Artelasticin 5471311 Drug sensitive
Antineoplastic-690266 5469577 Drug sensitive
3-Deazauridine 54684286 Drug sensitive
3,19-(4-Acetamido)benzylidineandrographolide 54612901 Drug sensitive
Herveline O 5459269 Drug sensitive
Betuletol 5459196 Drug sensitive
Cuspidatin C 5459164 Drug sensitive
Thiram 5455 Drug sensitive
Piritrexim isethionate 54368 Drug sensitive
(E)-1-(2,5-Dihydroxyphenyl)ethene-2-isonitrile 5388136 Drug sensitive
(1E,4E)-1,5-Dipyridin-3-ylpenta-1,4-dien-3-one 5382674 Drug sensitive
Crassin, acetate 5355441 Drug sensitive
Rozex 5353923 Drug sensitive
MX2 hydrochloride 5351347 Drug sensitive
Dihydro-5-azacytidine 5351280 Drug sensitive
7-(3-Methoxyphenyl)-N-(pyridin-4-ylmethylideneamino)-5H-pyrrolo[3,2-d]pyrimidin-4-amine 53239944 Drug sensitive
Vorinostat 5311 Drug sensitive
Improsulfan hydrochloride 5284401 Drug sensitive
Kekule 499328 Drug sensitive
Pyrimethamine 4993 Drug sensitive
10-Hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12-dodecahydro-1H-picene-4a-carboxylic acid 495604 Drug sensitive
Propyl gallate 4947 Drug resistant
1,4-Benzoquinone 4650 Drug sensitive
Melphalan 460612 Drug sensitive
Aclarubicin 451415 Drug sensitive
Ossirene 451379 Drug sensitive
Mycophenolic acid 446541 Drug sensitive
1-(4-(Benzyloxy)phenyl)-3-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl)phenyl)urea 44587530 Drug sensitive
Isopinnatal 44558939 Drug sensitive
Iproplatin 44214 Drug sensitive
Di-n-octyl-secalonsaure A 430141 Drug sensitive
S-(Dimethylarsino)-3-mercapto-1,2-propyl dibenzoate 406481 Drug sensitive
Aminopyrimidine-CH3 406278 Drug sensitive
Mechlorethamine 4033 Drug sensitive
Artelastin 399488 Drug sensitive
Cbz-[Lys3]-Didemnin B 398464 Drug resistant
Loratadine 3957 Drug sensitive
2,5-Bis(aziridin-1-yl)-3-(hydroxymethyl)-6-methylcyclohexa-2,5-diene-1,4-dione 394347 Drug sensitive
Sjg-136 393111 Drug sensitive
Leflunomide 3899 Drug sensitive
beta-Lapachone 3885 Drug sensitive
Lapachol 3884 Drug sensitive
Benzo[1,2-b:5,4-b']dithiophene-4,8-dione, 2-acetyl- 388028 Drug sensitive
3-(4-Fluorophenyl)-3-(4-hydroxy-2-methylphenyl)-2-benzofuran-1(3H)-one 387973 Drug resistant
1,3-Diphenyl-6-((triphenylphosphoranylidene)amino)-2,4(1H,3H)-pyrimidinedione 387460 Drug sensitive
Acetic acid,4,7,10-tetraazacyclododecane-1,7-diyl]bis 387352 Drug sensitive
L-LYS-L-p-NO2Phe-L-Ala-L-p-NO2PheNH2 386384 Drug sensitive
Stereoisomer of NSC 674066-O 384359 Drug sensitive
3-(4-Fluorophenyl)-3-(4-acetoxy-2-methylphenyl)phthalide 383342 Drug resistant
1-Azido-2-phenyl-3-phenalenone 381891 Drug sensitive
2-Acetyl-1,2-dihydroellipticine 376328 Drug resistant
Sanguilutine pseudobase 371258 Drug sensitive
1,2-Dimethyl-phenothiazone 369387 Drug sensitive
4-Nitro-6-(trifluoromethyl)-2,1,3-benzoselenadiazole 362897 Drug sensitive
Aplidazole C . TFA 362402 Drug sensitive
Predorine 333830 Drug sensitive
Rocaglamide 331783 Drug sensitive
Pinafide 327045 Drug sensitive
2,3-Dimethoxy-5-naphthalen-2-ylsulfanylcyclohexa-2,5-diene-1,4-dione 314728 Drug sensitive
Cytosine, 1beta-D-arabinofuranosyl-N(sup 4)-stearoyl- 304673 Drug sensitive
Flurocitabine 3034016 Drug sensitive
P-Ara-C 282479 Drug sensitive
Dichloroallyl lawsone 277767 Drug sensitive
6-Bromotoyocamycin 270861 Drug sensitive
2'-Deoxy-5-(trifluoromethyl)uridine 253083 Drug sensitive
2-(7-Aminotriazolo[4,5-d]pyrimidin-3-yl)-5-(hydroxymethyl)oxolane-3,4-diol 251928 Drug sensitive
2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-N-[2-(methylamino)ethyl]-1H-imidazo[4,5-c]pyridine-7-carboxamide 25023715 Drug resistant
9H-Purine, 6-(o-chlorobenzylthio)-9-(2-chloroethyl)- 246231 Drug sensitive
9H-Purine, 6-(benzylthio)-9-(2-chloroethyl)- 246230 Drug sensitive
Antimycin A3 245869 Drug sensitive
Prumycin HCl 24197905 Drug resistant
Cinerubin A hcl 24196924 Drug sensitive
9H-Purine, 2-amino-6-(o-chlorobenzylthio)-9-propyl- 239486 Drug sensitive
Spongiaquinone 23424796 Drug resistant
[(1S,2Z,4R,8R,9R,11R,13S)-13-Acetyloxy-1-hydroxy-2,11-dimethyl-7-methylidene-6-oxo-5,14-dioxatricyclo[9.2.1.04,8]tetradec-2-en-9-yl] 2-methylpropanoate 23255746 Drug sensitive
Amsacrine 2179 Drug sensitive
Pirarubicin hydrochloride 20846247 Drug sensitive
7,8-Dihydroxyflavone 1880 Drug sensitive
Sudan II 18386 Drug sensitive
4-Chloro-5-phenoxy-3H-1,2-dithiole-3-thione 16766044 Drug sensitive
Azaribine 16574 Drug sensitive
(2Z,9E,13Z,15E)-4',11-Dihydroxy-2,4',9-trimethylspiro[3-aza-1(2,4)-thiazolacyclohexadecaphanene-6,3'-[1,2]dithiolane]-9,13,15-triene-4,5',12-trione 2'-oxide 154730760 Drug sensitive
Methyl (3'R)-3,4',9',10-tetrahydroxy-3'-[(2S,4R,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-7'-methoxy-5',8',9-trioxospiro[3,4-dihydropyrano[4,3-g]chromene-2,2'-3H-benzo[f][1]benzofuran]-7-carboxylate 137326876 Drug sensitive
C8, Carbonyl prodigiosine 135540857 Drug sensitive
5-[(E)-[Amino(methyl)amino]azo]-1H-imidazole-4-carboxamide 135493930 Drug sensitive
Cysteine, S-[(4-aminocarbonyl-1H-imidazol-5-yl)azo]- 135493928 Drug sensitive
Emofolin sodium 135475347 Drug sensitive
8-Azahypoxanthine 135410720 Drug sensitive
Raltitrexed 135400182 Drug sensitive
DTIC-Dome 135398738 Drug sensitive
(2S,4S,5R)-20-De(1-hydroxypropyl)-6-demethyl-2,6-diethyl-5-hydroxy-20-(1-hydroxybutyl)lysocellin 124081057 Drug sensitive
p-Toluquinone 11122 Drug sensitive
Gentian violet 11057 Drug sensitive
Withajardin C 102469053 Drug sensitive
(7S,9S)-7-[[(3As,4S,7aS)-1-[[(3aS,4S,7aS)-4-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-2,3a,4,6,7,7a-hexahydropyrano[4,3-d][1,3]oxazol-1-yl]methyl]-4-methyl-2,3a,4,6,7,7a-hexahydropyrano[4,3-d][1,3]oxazol-6-yl]oxy]-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione 101713728 Drug sensitive
(1S,2R,4R,6S,11R,12S,15R,18S,19R,20R,21S,23R,26R)-15-Hydroxy-11,18,21-trimethyl-5,17,24,28,29-pentaoxanonacyclo[17.9.1.11,20.02,12.04,6.06,11.015,19.018,23.021,26]triacont-8-ene-10,16,25,30-tetrone 101528280 Drug sensitive
Erigerol 101318126 Drug sensitive
[(1S,2S,4Z,8Z,12R,13S)-12-Hydroxy-4,8,12-trimethyl-16-methylidene-15-oxo-14-oxabicyclo[11.3.1]heptadeca-4,8-dien-2-yl] acetate 100921072 Drug sensitive
Tocladesine 100299 Drug sensitive
(1R,2E,6R,10E,11aS,13S,14aR)-6-(2-(benzyloxy)ethyl)-1,13-dihydroxy-6,7,8,9,12,13,14,14a-octahydro-1H-cyclopenta[f][1]oxacyclotridecin-4(11aH)-one - Drug resistant
2,3-dihydro-1,2-syn-3-[phenylseleno]brefeldin a - Drug resistant
9-methoxy-5-hydroxycamptothecin - Drug resistant
tp4ek - Drug resistant
(Z)-N-phenyl-3-(3,4,5-trimethoxystyryl)pyridin-2-amine - Drug sensitive
1,2-naphthoquinone, 3,7-dimethyl- - Drug sensitive
1h-benzimidazole, 5,5'-dithiobis[2-(trifluoromethyl)- (9ci) - Drug sensitive
2-[(3,4-dicloro)anilino]-3-phenyl-5,7-diamino quinoxaline - Drug sensitive
3',4',5'-trimethoxy-3-hydroxy flavone - Drug sensitive
4-(2-pyridinyl)-5h-1,2,3-dithiazole-5-thione - Drug sensitive
4-[3-(3,4-dihydro-1H-isoquinolin-2-yl)prop-1-en-2-yl]-N-pyrazin-2-ylbenzamide - Drug sensitive
4-quinazolone, 7-amino-3-(4-methoxyphenyl)-, hydrate - Drug sensitive
5.alpha.,25d-spirostan-3.beta.-ol glycoside - Drug sensitive
9h-quino[4,3,2-de][1,10]phenanthrolin-9-one, 5-methoxy- - Drug sensitive
acetamide, n-(2-mercaptoethyl)-, benzoate (6ci, 7ci) - Drug sensitive
b676297k277 3',4'-deoxypsorospermin 3',4'-chlorohydrin - Drug sensitive
benzo[1,2-c:4,5-c']dipyrrole-1,3,5,7(2h,6h)-tetraimine - Drug sensitive
benzofurazan, 4-nitro-7-(2-pyridinylthio)-, n-oxide - Drug sensitive
bersaldegenin 1,3,5-orthoacetate - Drug sensitive
cis-2-hydroxymethyl-4-(5'-bromocytosin-1'-yl)-1,3-dioxolane - Drug sensitive
furan-2(3h)-one, 5-(4-methylphenyl)-3,3-diphenyl- - Drug sensitive
isoflavone, 5,7-dihydroxy-4'-nitro- - Drug sensitive
mercury, tetrakis(acetato)(2,3,4,5-thiophenetetrayl)tetra- - Drug sensitive
n,n'-bis(oxydiethylene)thiocarbamoylsulfenamide - Drug sensitive
phenol, 4,4'-(5,5'-biisoxazole-3,3'-diyl)bis- - Drug sensitive
propan-1-one, 2,3-dichloro-1,3-bis(4-methylphenyl)- - Drug sensitive
propanedinitrile, [(3,5-dibromo-2-ethoxyphenyl)methylene]- - Drug sensitive
(Z)-3-((2-(4-(trifluoromethyl)phenyl)-3H-benzo[d]imidazol-5-yl)methylene)indolin-2-one - Drug sensitive
[bis(aminomethyl)diethylsilane]dichloroplatinum (ii) - Drug sensitive
7-propanoyltaxol - Drug sensitive
Aminopterin Derivative - Drug sensitive
Annamycin Liposomal - Drug sensitive
antineoplastic-d665839 - Drug sensitive
Camptothecin Derivative - Drug sensitive
Carboxyphthalatoplatinum - Drug sensitive
chlorobis(4-ethyltropolonato)bismuth(iii) - Drug sensitive
CI-921: amsacrine derivative - Drug sensitive
Indenoisoquinoline derivative - Drug sensitive
insulin-methotrexate conjugate - Drug sensitive
merophan - Drug sensitive
mitaplatin - Drug sensitive
n-myristoyl-(s)-phenylalaninal diethylcetal - Drug sensitive
organosulfur compound - Drug sensitive
trimethyl(phenylthio)stannane - Drug sensitive
Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-519e-3p
Alocrest 60780 Drug interaction    RC00005536
5-Fluorouracil 3385 Drug interaction    RC00005535
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00005534
Tamoxifen 2733526 Drug interaction    RC00005537

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-519e-3p
Interactor2: SAMD12

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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