Basic Information:

  VIRBase ID:  

HHID00006349

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-519e-3p:  MIMAT0002829          RNF149:  NM_173647     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-519e-3p	RNF149
miRBase Accession/Entrez ID	MIMAT0002829	284996
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	DNAPTP2

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-519e-3p	rs1320260913 chr19:53680012    T/TA rs748109530 chr19:53680008    G/A rs756692397 chr19:53679994    T/C rs762638742 chr19:53679970    CTTTCTGTTTGAAAGAAAACAAAGTGCCTCCTTTTAGAGTG/C rs778834695 chr19:53679997    C/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	RNF149	chr2:101915612(-) A-I      intronic chr2:101903808(-) A-I      intronic chr2:101901535(-) A-I      intronic chr2:101911954(-) A-I      intronic chr2:101911939(-) A-I      intronic chr2:101904901(-) A-I      intronic chr2:101912014(-) A-I      intronic chr2:101912047(-) A-I      intronic chr2:101922488(-) A-I      intronic chr2:101920654(-) A-I      intronic chr2:101920796(-) A-I      intronic chr2:101897377(-) A-I      intronic chr2:101898141(-) A-I      intronic chr2:101900820(-) A-I      intronic chr2:101900836(-) A-I      intronic chr2:101900838(-) A-I      intronic chr2:101901476(-) A-I      intronic chr2:101903604(-) A-I      intronic chr2:101904893(-) A-I      intronic chr2:101904895(-) A-I      intronic chr2:101900934(-) A-I      intronic chr2:101904953(-) A-I      intronic chr2:101913921(-) A-I      intronic chr2:101913951(-) A-I      intronic chr2:101915394(-) A-I      intronic chr2:101915400(-) A-I      intronic chr2:101915408(-) A-I      intronic chr2:101917986(-) A-I      intronic chr2:101900807(-) A-I      intronic chr2:101907961(-) A-I      intronic chr2:101898095(-) A-I      intronic chr2:101893975(-) A-I      intronic chr2:101900816(-) A-I      intronic chr2:101900870(-) A-I      intronic chr2:101900949(-) A-I      intronic chr2:101893962(-) A-I      intronic chr2:101903662(-) A-I      intronic chr2:101903601(-) A-I      intronic chr2:101904931(-) A-I      intronic chr2:101901632(-) A-I      intronic chr2:101900996(-) A-I      intronic chr2:101907795(-) A-I      intronic chr2:101907884(-) A-I      intronic chr2:101908036(-) A-I      intronic chr2:101909039(-) A-I      intronic chr2:101893959(-) A-I      intronic chr2:101901029(-) A-I      intronic chr2:101901414(-) A-I      intronic chr2:101901442(-) A-I      intronic chr2:101901531(-) A-I      intronic chr2:101901537(-) A-I      intronic chr2:101906542(-) A-I      intronic chr2:101907737(-) A-I      intronic chr2:101909116(-) A-I      intronic chr2:101904828(-) A-I      intronic chr2:101909182(-) A-I      intronic chr2:101911868(-) A-I      intronic chr2:101911880(-) A-I      intronic chr2:101911917(-) A-I      intronic chr2:101911993(-) A-I      intronic chr2:101923854(-) A-I      intronic chr2:101923697(-) A-I      intronic chr2:101921473(-) A-I      intronic chr2:101921472(-) A-I      intronic chr2:101921414(-) A-I      intronic chr2:101921388(-) A-I      intronic chr2:101920772(-) A-I      intronic chr2:101920642(-) A-I      intronic chr2:101907790(-) A-I      intronic chr2:101912498(-) A-I      intronic chr2:101917903(-) A-I      intronic chr2:101913505(-) A-I      intronic chr2:101904584(-) A-I      intronic chr2:101904776(-) A-I      intronic chr2:101904824(-) A-I      intronic chr2:101919826(-) A-I      intronic chr2:101919816(-) A-I      intronic chr2:101919785(-) A-I      intronic chr2:101901563(-) A-I      intronic chr2:101901573(-) A-I      intronic chr2:101901592(-) A-I      intronic chr2:101919783(-) A-I      intronic chr2:101919782(-) A-I      intronic chr2:101919606(-) A-I      intronic chr2:101919443(-) A-I      intronic chr2:101919437(-) A-I      intronic chr2:101901597(-) A-I      intronic chr2:101896576(-) A-I      intronic chr2:101894896(-) A-I      intronic chr2:101919436(-) A-I      intronic chr2:101894734(-) A-I      intronic chr2:101894711(-) A-I      intronic chr2:101905947(-) A-I      intronic chr2:101905964(-) A-I      intronic chr2:101919409(-) A-I      intronic chr2:101919355(-) A-I      intronic chr2:101919302(-) A-I      intronic chr2:101901624(-) A-I      intronic chr2:101913436(-) A-I      intronic chr2:101918008(-) A-I      intronic chr2:101919428(-) A-I      intronic chr2:101897952(-) A-I      intronic chr2:101913533(-) A-I      intronic chr2:101913930(-) A-I      intronic chr2:101914824(-) A-I      intronic chr2:101906032(-) A-I      intronic chr2:101906067(-) A-I      intronic chr2:101906166(-) A-I      intronic chr2:101906199(-) A-I      intronic chr2:101906200(-) A-I      intronic chr2:101906211(-) A-I      intronic chr2:101906228(-) A-I      intronic chr2:101906293(-) A-I      intronic chr2:101906479(-) A-I      intronic chr2:101906530(-) A-I      intronic chr2:101917828(-) A-I      intronic chr2:101903752(-) A-I      intronic chr2:101915367(-) A-I      intronic chr2:101917016(-) A-I      intronic chr2:101912011(-) A-I      intronic chr2:101912015(-) A-I      intronic chr2:101912071(-) A-I      intronic chr2:101912085(-) A-I      intronic chr2:101912121(-) A-I      intronic chr2:101912370(-) A-I      intronic chr2:101896612(-) A-I      intronic chr2:101897372(-) A-I      intronic chr2:101897434(-) A-I      intronic chr2:101897439(-) A-I      intronic chr2:101903684(-) A-I      intronic chr2:101906045(-) A-I      intronic chr2:101923737(-) A-I      intronic chr2:101912001(-) A-I      intronic chr2:101914892(-) A-I      intronic chr2:101915446(-) A-I      intronic chr2:101907786(-) A-I      intronic chr2:101900899(-) A-I      intronic chr2:101914680(-) A-I      intronic chr2:101920821(-) A-I      intronic chr2:101912090(-) A-I      intronic chr2:101914691(-) A-I      intronic chr2:101920776(-) A-I      intronic chr2:101912494(-) A-I      intronic chr2:101917887(-) A-I      intronic chr2:101919875(-) A-I      intronic chr2:101912371(-) A-I      intronic chr2:101921441(-) A-I      intronic chr2:101911999(-) A-I      intronic chr2:101913911(-) A-I      intronic chr2:101903652(-) A-I      intronic chr2:101917951(-) A-I      intronic chr2:101903648(-) A-I      intronic chr2:101919238(-) A-I      intronic chr2:101921482(-) A-I      intronic chr2:101919293(-) A-I      intronic chr2:101900931(-) A-I      intronic chr2:101915495(-) A-I      intronic chr2:101901468(-) A-I      intronic chr2:101915497(-) A-I      intronic chr2:101917032(-) A-I      intronic chr2:101921496(-) A-I      intronic chr2:101900960(-) A-I      intronic chr2:101901446(-) A-I      intronic chr2:101919318(-) A-I      intronic chr2:101898259(-) A-I      intronic chr2:101919654(-) A-I      intronic chr2:101903702(-) A-I      intronic chr2:101906254(-) A-I      intronic chr2:101906459(-) A-I      intronic chr2:101897379(-) A-I      intronic chr2:101913555(-) A-I      intronic chr2:101903527(-) A-I      intronic chr2:101917858(-) A-I      intronic chr2:101919675(-) A-I      intronic chr2:101897451(-) A-I      intronic chr2:101914024(-) A-I      intronic chr2:101923674(-) A-I      intronic chr2:101897352(-) A-I      intronic chr2:101921431(-) A-I      intronic chr2:101923742(-) A-I      intronic chr2:101898123(-) A-I      intronic chr2:101901454(-) A-I      intronic chr2:101901530(-) A-I      intronic chr2:101915401(-) A-I      intronic chr2:101897490(-) A-I      intronic chr2:101913588(-) A-I      intronic chr2:101914811(-) A-I      intronic chr2:101901485(-) A-I      intronic chr2:101914787(-) A-I      intronic chr2:101912539(-) A-I      intronic chr2:101896510(-) A-I      intronic chr2:101914805(-) A-I      intronic chr2:101896591(-) A-I      intronic chr2:101893989(-) A-I      intronic chr2:101912380(-) A-I      intronic chr2:101921427(-) A-I      intronic chr2:101900824(-) A-I      intronic chr2:101900961(-) A-I      intronic chr2:101900885(-) A-I      intronic chr2:101919674(-) A-I      intronic chr2:101917856(-) A-I      intronic chr2:101917949(-) A-I      intronic chr2:101908024(-) A-I      intronic chr2:101900825(-) A-I      intronic chr2:101904489(-) A-I      intronic chr2:101907728(-) A-I      intronic chr2:101900799(-) A-I      intronic chr2:101897388(-) A-I      intronic chr2:101898032(-) A-I      intronic chr2:101917104(-) A-I      intronic chr2:101917110(-) A-I      intronic chr2:101919681(-) A-I      intronic chr2:101923717(-) A-I      intronic chr2:101921565(-) A-I      intronic chr2:101904960(-) A-I      intronic chr2:101914768(-) A-I      intronic chr2:101921375(-) A-I      intronic chr2:101894018(-) A-I      intronic chr2:101894702(-) A-I      intronic chr2:101901384(-) A-I      intronic chr2:101903721(-) A-I      intronic chr2:101914761(-) A-I      intronic chr2:101903672(-) A-I      intronic chr2:101906164(-) A-I      intronic chr2:101923868(-) A-I      intronic chr2:101903701(-) A-I      intronic chr2:101923922(-) A-I      intronic chr2:101900921(-) A-I      intronic chr2:101919725(-) A-I      intronic chr2:101893919(-) A-I      intronic chr2:101897449(-) A-I      intronic chr2:101894884(-) A-I      intronic chr2:101920747(-) A-I      intronic chr2:101904778(-) A-I      intronic chr2:101897329(-) A-I      intronic chr2:101898119(-) A-I      intronic chr2:101920735(-) A-I      intronic chr2:101896538(-) A-I      intronic chr2:101901480(-) A-I      intronic chr2:101901579(-) A-I      intronic chr2:101913979(-) A-I      intronic chr2:101920837(-) A-I      intronic chr2:101918018(-) A-I      intronic chr2:101900857(-) A-I      intronic chr2:101894009(-) A-I      intronic chr2:101917976(-) A-I      intronic chr2:101911870(-) A-I      intronic chr2:101912566(-) A-I      intronic chr2:101913973(-) A-I      intronic chr2:101914711(-) A-I      intronic chr2:101919792(-) A-I      intronic chr2:101893880(-) A-I      intronic chr2:101906055(-) A-I      intronic chr2:101896492(-) A-I      intronic chr2:101900894(-) A-I      intronic chr2:101893947(-) A-I      intronic chr2:101920711(-) A-I      intronic chr2:101919868(-) A-I      intronic chr2:101906637(-) A-I      intronic chr2:101914700(-) A-I      intronic chr2:101897340(-) A-I      intronic chr2:101907963(-) A-I      intronic chr2:101898162(-) A-I      intronic chr2:101898258(-) A-I      intronic chr2:101913559(-) A-I      intronic chr2:101906387(-) A-I      intronic chr2:101920857(-) A-I      intronic chr2:101893920(-) A-I      intronic chr2:101904772(-) A-I      intronic chr2:101900797(-) A-I      intronic chr2:101917112(-) A-I      intronic chr2:101900980(-) A-I      intronic chr2:101914690(-) A-I      intronic chr2:101897448(-) A-I      intronic chr2:101912497(-) A-I      intronic chr2:101914020(-) A-I      intronic chr2:101903780(-) A-I      intronic chr2:101906555(-) A-I      intronic chr2:101904820(-) A-I      intronic chr2:101920751(-) A-I      intronic chr2:101918041(-) A-I      intronic chr2:101896594(-) A-I      intronic chr2:101920693(-) A-I      intronic chr2:101918047(-) A-I      intronic chr2:101914096(-) A-I      intronic chr2:101903649(-) A-I      intronic chr2:101917915(-) A-I      intronic chr2:101920691(-) A-I      intronic chr2:101917057(-) A-I      intronic chr2:101912572(-) A-I      intronic chr2:101919286(-) A-I      intronic chr2:101918040(-) A-I      intronic chr2:101897401(-) A-I      intronic chr2:101893883(-) A-I      intronic chr2:101906462(-) A-I      intronic chr2:101900887(-) A-I      intronic chr2:101896586(-) A-I      intronic chr2:101900895(-) A-I      intronic chr2:101900798(-) A-I      intronic chr2:101908017(-) A-I      intronic chr2:101901578(-) A-I      intronic chr2:101917946(-) A-I      intronic chr2:101897374(-) A-I      intronic chr2:101901616(-) A-I      intronic chr2:101898054(-) A-I      intronic chr2:101906043(-) A-I      intronic chr2:101920815(-) A-I      intronic chr2:101912553(-) A-I      intronic chr2:101909226(-) A-I      intronic chr2:101905999(-) A-I      intronic chr2:101904565(-) A-I      intronic chr2:101901481(-) A-I      intronic chr2:101914040(-) A-I      intronic chr2:101913983(-) A-I      intronic chr2:101894123(-) A-I      intronic chr2:101917106(-) A-I      intronic chr2:101919359(-) A-I      intronic chr2:101901037(-) A-I      intronic chr2:101919612(-) A-I      intronic chr2:101903616(-) A-I      intronic chr2:101907751(-) A-I      intronic chr2:101912060(-) A-I      intronic chr2:101913887(-) A-I      intronic chr2:101923840(-) A-I      intronic chr2:101903539(-) A-I      intronic chr2:101893988(-) A-I      intronic chr2:101923658(-) A-I      intronic chr2:101914087(-) A-I      intronic chr2:101914778(-) A-I      intronic chr2:101903749(-) A-I      intronic chr2:101898127(-) A-I      intronic chr2:101923702(-) A-I      intronic chr2:101919650(-) A-I      intronic chr2:101903640(-) A-I      intronic chr2:101900876(-) A-I      intronic chr2:101896581(-) A-I      intronic chr2:101904919(-) A-I      intronic chr2:101919683(-) A-I      intronic chr2:101906085(-) A-I      intronic chr2:101896511(-) A-I      intronic chr2:101901633(-) A-I      intronic chr2:101920734(-) A-I      intronic chr2:101904870(-) A-I      intronic chr2:101923930(-) A-I      intronic chr2:101919390(-) A-I      intronic chr2:101914846(-) A-I      intronic chr2:101906520(-) A-I      intronic chr2:101903538(-) A-I      intronic chr2:101912342(-) A-I      intronic chr2:101906001(-) A-I      intronic chr2:101919356(-) A-I      intronic chr2:101901639(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	RNF149	chr2:101901037(-) A-I intron -    15545495 chr2:101896581(-) A-I intron -    21960545   //22327324 chr2:101897379(-) A-I intron -    22327324 chr2:101897490(-) A-I intron -    21960545   //22327324 chr2:101900960(-) A-I intron -    22327324 chr2:101919320(-) A-I intron -    22327324 chr2:101920852(-) A-I intron -    22327324 chr2:101923702(-) A-I intron -    22327324 chr2:101894150(-) A-I intron -    21960545 chr2:101898119(-) A-I intron -    21960545 chr2:101900899(-) A-I intron -    21960545 chr2:101900931(-) A-I intron -    21960545 chr2:101901035(-) A-I intron -    21960545 chr2:101901639(-) A-I intron -    21960545 chr2:101904919(-) A-I intron -    21960545 chr2:101911939(-) A-I intron -    21960545 chr2:101912539(-) A-I intron -    21960545 chr2:101912546(-) A-I intron -    21960545 chr2:101912566(-) A-I intron -    21960545 chr2:101913983(-) A-I intron -    21960545 chr2:101914087(-) A-I intron -    21960545 chr2:101914101(-) A-I intron -    21960545 chr2:101914763(-) A-I intron -    21960545 chr2:101915612(-) A-I intron -    21960545 chr2:101917030(-) A-I intron -    21960545 chr2:101917049(-) A-I intron -    21960545 chr2:101919356(-) A-I intron -    21960545 chr2:101919716(-) A-I intron -    21960545 chr2:101919725(-) A-I intron -    21960545 chr2:101919875(-) A-I intron -    21960545 chr2:101921441(-) A-I intron -    21960545 chr2:101921560(-) A-I intron -    21960545 chr2:101921565(-) A-I intron -    21960545 chr2:101893883(-) A-G intron -    22484847 chr2:101893920(-) A-G intron -    22484847 chr2:101893989(-) A-G intron -    22484847 chr2:101894009(-) A-G intron -    22484847 chr2:101896555(-) A-G intron -    22484847 chr2:101896581(-) A-G intron -    22484847 chr2:101896586(-) A-G intron -    22484847 chr2:101897379(-) A-G intron -    22484847 chr2:101897444(-) A-G intron -    22484847 chr2:101897448(-) A-G intron -    22484847 chr2:101897490(-) A-G intron -    22484847 chr2:101898029(-) A-G intron -    22484847 chr2:101898032(-) A-G intron -    22484847 chr2:101898054(-) A-G intron -    22484847 chr2:101898101(-) A-G intron -    22484847 chr2:101898119(-) A-G intron -    22484847 chr2:101898162(-) A-G intron -    22484847 chr2:101898258(-) A-G intron -    22484847 chr2:101900797(-) A-G intron -    22484847 chr2:101900798(-) A-G intron -    22484847 chr2:101900824(-) A-G intron -    22484847 chr2:101900839(-) A-G intron -    22484847 chr2:101900876(-) A-G intron -    22484847 chr2:101900887(-) A-G intron -    22484847 chr2:101900894(-) A-G intron -    22484847 chr2:101900921(-) A-G intron -    22484847 chr2:101900931(-) A-G intron -    22484847 chr2:101900935(-) A-G intron -    22484847 chr2:101900960(-) A-G intron -    22484847 chr2:101900961(-) A-G intron -    22484847 chr2:101901035(-) A-G intron -    22484847 chr2:101901454(-) A-G intron -    22484847 chr2:101901553(-) A-G intron -    22484847 chr2:101901579(-) A-G intron -    22484847 chr2:101901610(-) A-G intron -    22484847 chr2:101901620(-) A-G intron -    22484847 chr2:101901639(-) A-G intron -    22484847 chr2:101903701(-) A-G intron -    22484847 chr2:101903702(-) A-G intron -    22484847 chr2:101903724(-) A-G intron -    22484847 chr2:101903749(-) A-G intron -    22484847 chr2:101904820(-) A-G intron -    22484847 chr2:101904851(-) A-G intron -    22484847 chr2:101904870(-) A-G intron -    22484847 chr2:101904879(-) G-A intron -    22484847 chr2:101904882(-) A-G intron -    22484847 chr2:101904919(-) A-G intron -    22484847 chr2:101904923(-) G-C intron -    22484847 chr2:101906084(-) A-G intron -    22484847 chr2:101906085(-) A-G intron -    22484847 chr2:101906254(-) A-G intron -    22484847 chr2:101906520(-) A-G intron -    22484847 chr2:101911999(-) A-G intron -    22484847 chr2:101912380(-) A-G intron -    22484847 chr2:101912497(-) A-G intron -    22484847 chr2:101912539(-) A-G intron -    22484847 chr2:101912546(-) A-G intron -    22484847 chr2:101912553(-) A-G intron -    22484847 chr2:101912566(-) A-G intron -    22484847 chr2:101913547(-) A-G intron -    22484847 chr2:101913555(-) A-G intron -    22484847 chr2:101913559(-) A-G intron -    22484847 chr2:101913588(-) A-G intron -    22484847 chr2:101913887(-) A-G intron -    22484847 chr2:101913939(-) A-G intron -    22484847 chr2:101913943(-) A-G intron -    22484847 chr2:101913973(-) A-G intron -    22484847 chr2:101913983(-) A-G intron -    22484847 chr2:101914020(-) A-G intron -    22484847 chr2:101914040(-) A-G intron -    22484847 chr2:101914048(-) A-G intron -    22484847 chr2:101914096(-) A-G intron -    22484847 chr2:101914690(-) A-G intron -    22484847 chr2:101914691(-) A-G intron -    22484847 chr2:101914711(-) A-G intron -    22484847 chr2:101914763(-) A-G intron -    22484847 chr2:101914778(-) A-G intron -    22484847 chr2:101914787(-) A-G intron -    22484847 chr2:101914805(-) A-G intron -    22484847 chr2:101914811(-) A-G intron -    22484847 chr2:101914846(-) A-G intron -    22484847 chr2:101914881(-) A-G intron -    22484847 chr2:101914892(-) A-G intron -    22484847 chr2:101915495(-) A-G intron -    22484847 chr2:101917104(-) A-G intron -    22484847 chr2:101917106(-) A-G intron -    22484847 chr2:101917110(-) A-G intron -    22484847 chr2:101918047(-) A-G intron -    22484847 chr2:101919286(-) A-G intron -    22484847 chr2:101919318(-) A-G intron -    22484847 chr2:101919320(-) A-G intron -    22484847 chr2:101919356(-) A-G intron -    22484847 chr2:101919390(-) A-G intron -    22484847 chr2:101919398(-) A-G intron -    22484847 chr2:101919612(-) A-G intron -    22484847 chr2:101919650(-) A-G intron -    22484847 chr2:101919674(-) A-G intron -    22484847 chr2:101919675(-) A-G intron -    22484847 chr2:101919681(-) A-G intron -    22484847 chr2:101919716(-) A-G intron -    22484847 chr2:101919725(-) A-G intron -    22484847 chr2:101919875(-) A-G intron -    22484847 chr2:101920691(-) A-G intron -    22484847 chr2:101920692(-) A-G intron -    22484847 chr2:101920734(-) A-G intron -    22484847 chr2:101920737(-) A-G intron -    22484847 chr2:101920747(-) A-G intron -    22484847 chr2:101920751(-) A-G intron -    22484847 chr2:101920776(-) A-G intron -    22484847 chr2:101920852(-) A-G intron -    22484847 chr2:101921376(-) A-G intron -    22484847 chr2:101921431(-) A-G intron -    22484847 chr2:101921485(-) A-G intron -    22484847 chr2:101921565(-) A-G intron -    22484847 chr2:101923674(-) A-G intron -    22484847 chr2:101923702(-) A-G intron -    22484847 chr2:101923737(-) A-G intron -    22484847 chr2:101923742(-) A-G intron -    22484847 chr2:101923768(-) A-G intron -    22484847 chr2:101923782(-) A-G intron -    22484847 chr2:101923868(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	RNF149	chr2:101887801-101887802(-) m6A 3'UTR//exon       27773535 chr2:101887829-101887830(-) m6A 3'UTR//exon       27773535 chr2:101887891-101887892(-) m6A 3'UTR//exon       27773535 chr2:101887974-101887975(-) m6A 3'UTR//exon       24981863//27773535 chr2:101888128-101888129(-) m6A 3'UTR//exon       24284625//27773535 chr2:101888173-101888174(-) m6A 3'UTR//exon       24284625//27773535 chr2:101889316-101889317(-) m6A exon//intron       27773535 chr2:101889340-101889341(-) m6A exon//intron       27773535 chr2:101889416-101889417(-) m6A intron       26404942 chr2:101889458-101889459(-) Y intron       26075521 chr2:101889605-101889606(-) m6A 3'UTR       27773535 chr2:101889630-101889631(-) m6A 3'UTR       27773535 chr2:101893372-101893373(-) m6A 3'UTR//intron       26404942 chr2:101893416-101893417(-) m6A 3'UTR//intron       26404942 chr2:101893446-101893447(-) m6A 3'UTR//intron       26404942 chr2:101893458-101893459(-) m6A 3'UTR//intron       26404942 chr2:101893475-101893476(-) m6A 3'UTR//intron       26404942 chr2:101893529-101893530(-) m6A 3'UTR//intron       26404942 chr2:101893554-101893555(-) m6A 3'UTR//intron       24981863//26404942 chr2:101893647-101893648(-) m6A 3'UTR//intron       24981863//26404942//22608085 chr2:101893655-101893656(-) m6A 3'UTR//intron       24981863//26404942//22608085 chr2:101893711-101893712(-) m6A CDS//intron       24981863//26404942//27773535 chr2:101897984-101897985(-) m6A exon//intron       24981863//27773535 chr2:101911640-101911641(-) m6A CDS       24209618 chr2:101924616-101924617(-) m6A CDS       24209618//22575960 chr2:101924685-101924686(-) m6A CDS       24209618//27371828//27773536//22575960 chr2:101924793-101924794(-) m6A CDS       24209618//27371828//27773536//22575960 chr2:101924899-101924900(-) m6A CDS       24209618//27773536//22575960 chr2:101924907-101924908(-) m6A CDS       24209618//27773536//22575960 chr2:101924922-101924923(-) m6A CDS       24209618//27773536//22575960

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-519e-3p	Exosome Brain tissue     23382797 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
	RNF149	Chromatin K562 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Insoluble cytoplasm HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells     - Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function
ncDR	hsa-miR-519e-3p	Iodine Green 9956454 Drug sensitive 2-(2,4-Difluorophenyl)-4,5,6,7-tetrafluoro-1H-isoindole-1,3(2H)-dione 9905583 Drug sensitive Kahalalide F 9898671 Drug resistant CID 9604911 9604911 Drug sensitive Actinomycin X4357G methoxime 9573583 Drug sensitive Indolo[2,1-b]quinazoline-6,12-dione 73549 Drug sensitive Venenatine 73061 Drug sensitive Redoxal 72571 Drug sensitive Piperidinium pentamethylenedithiocarbamate 72508 Drug sensitive 4-(2-Naphthylamino)phenol 7141 Drug sensitive Tolonium chloride 7083 Drug sensitive Sulbentine 67686 Drug sensitive Reactive Blue 2 656725 Drug sensitive (2R,3R,4S,5R)-2-(6-Benzylsulfanylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol 6477178 Drug sensitive Vicenistatin 6438888 Drug sensitive Verrucarin A 6326658 Drug sensitive Deferoxamine hydrochloride 62880 Drug sensitive Cytarabine 6253 Drug sensitive Bizelesin 60794 Drug sensitive Tributyrin 6050 Drug sensitive Triethylenemelamine 5799 Drug sensitive Teclothiazide potassium 56841138 Drug sensitive (3beta)-3-((4-O-beta-D Glucopyranosyl-beta-D-xylopyranosyl)oxy)-14-hydroxy-19-oxocarda-4,20(22)-dienolide 56840951 Drug sensitive Caracemide 54747 Drug sensitive 7Z-Plakortide H 5472712 Drug sensitive Artelasticin 5471311 Drug sensitive Antineoplastic-690266 5469577 Drug sensitive 3-Deazauridine 54684286 Drug sensitive 3,19-(4-Acetamido)benzylidineandrographolide 54612901 Drug sensitive Herveline O 5459269 Drug sensitive Betuletol 5459196 Drug sensitive Cuspidatin C 5459164 Drug sensitive Thiram 5455 Drug sensitive Piritrexim isethionate 54368 Drug sensitive (E)-1-(2,5-Dihydroxyphenyl)ethene-2-isonitrile 5388136 Drug sensitive (1E,4E)-1,5-Dipyridin-3-ylpenta-1,4-dien-3-one 5382674 Drug sensitive Crassin, acetate 5355441 Drug sensitive Rozex 5353923 Drug sensitive MX2 hydrochloride 5351347 Drug sensitive Dihydro-5-azacytidine 5351280 Drug sensitive 7-(3-Methoxyphenyl)-N-(pyridin-4-ylmethylideneamino)-5H-pyrrolo[3,2-d]pyrimidin-4-amine 53239944 Drug sensitive Vorinostat 5311 Drug sensitive Improsulfan hydrochloride 5284401 Drug sensitive Kekule 499328 Drug sensitive Pyrimethamine 4993 Drug sensitive 10-Hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12-dodecahydro-1H-picene-4a-carboxylic acid 495604 Drug sensitive Propyl gallate 4947 Drug resistant 1,4-Benzoquinone 4650 Drug sensitive Melphalan 460612 Drug sensitive Aclarubicin 451415 Drug sensitive Ossirene 451379 Drug sensitive Mycophenolic acid 446541 Drug sensitive 1-(4-(Benzyloxy)phenyl)-3-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl)phenyl)urea 44587530 Drug sensitive Isopinnatal 44558939 Drug sensitive Iproplatin 44214 Drug sensitive Di-n-octyl-secalonsaure A 430141 Drug sensitive S-(Dimethylarsino)-3-mercapto-1,2-propyl dibenzoate 406481 Drug sensitive Aminopyrimidine-CH3 406278 Drug sensitive Mechlorethamine 4033 Drug sensitive Artelastin 399488 Drug sensitive Cbz-[Lys3]-Didemnin B 398464 Drug resistant Loratadine 3957 Drug sensitive 2,5-Bis(aziridin-1-yl)-3-(hydroxymethyl)-6-methylcyclohexa-2,5-diene-1,4-dione 394347 Drug sensitive Sjg-136 393111 Drug sensitive Leflunomide 3899 Drug sensitive beta-Lapachone 3885 Drug sensitive Lapachol 3884 Drug sensitive Benzo[1,2-b:5,4-b']dithiophene-4,8-dione, 2-acetyl- 388028 Drug sensitive 3-(4-Fluorophenyl)-3-(4-hydroxy-2-methylphenyl)-2-benzofuran-1(3H)-one 387973 Drug resistant 1,3-Diphenyl-6-((triphenylphosphoranylidene)amino)-2,4(1H,3H)-pyrimidinedione 387460 Drug sensitive Acetic acid,4,7,10-tetraazacyclododecane-1,7-diyl]bis 387352 Drug sensitive L-LYS-L-p-NO2Phe-L-Ala-L-p-NO2PheNH2 386384 Drug sensitive Stereoisomer of NSC 674066-O 384359 Drug sensitive 3-(4-Fluorophenyl)-3-(4-acetoxy-2-methylphenyl)phthalide 383342 Drug resistant 1-Azido-2-phenyl-3-phenalenone 381891 Drug sensitive 2-Acetyl-1,2-dihydroellipticine 376328 Drug resistant Sanguilutine pseudobase 371258 Drug sensitive 1,2-Dimethyl-phenothiazone 369387 Drug sensitive 4-Nitro-6-(trifluoromethyl)-2,1,3-benzoselenadiazole 362897 Drug sensitive Aplidazole C . TFA 362402 Drug sensitive Predorine 333830 Drug sensitive Rocaglamide 331783 Drug sensitive Pinafide 327045 Drug sensitive 2,3-Dimethoxy-5-naphthalen-2-ylsulfanylcyclohexa-2,5-diene-1,4-dione 314728 Drug sensitive Cytosine, 1beta-D-arabinofuranosyl-N(sup 4)-stearoyl- 304673 Drug sensitive Flurocitabine 3034016 Drug sensitive P-Ara-C 282479 Drug sensitive Dichloroallyl lawsone 277767 Drug sensitive 6-Bromotoyocamycin 270861 Drug sensitive 2'-Deoxy-5-(trifluoromethyl)uridine 253083 Drug sensitive 2-(7-Aminotriazolo[4,5-d]pyrimidin-3-yl)-5-(hydroxymethyl)oxolane-3,4-diol 251928 Drug sensitive 2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-N-[2-(methylamino)ethyl]-1H-imidazo[4,5-c]pyridine-7-carboxamide 25023715 Drug resistant 9H-Purine, 6-(o-chlorobenzylthio)-9-(2-chloroethyl)- 246231 Drug sensitive 9H-Purine, 6-(benzylthio)-9-(2-chloroethyl)- 246230 Drug sensitive Antimycin A3 245869 Drug sensitive Prumycin HCl 24197905 Drug resistant Cinerubin A hcl 24196924 Drug sensitive 9H-Purine, 2-amino-6-(o-chlorobenzylthio)-9-propyl- 239486 Drug sensitive Spongiaquinone 23424796 Drug resistant [(1S,2Z,4R,8R,9R,11R,13S)-13-Acetyloxy-1-hydroxy-2,11-dimethyl-7-methylidene-6-oxo-5,14-dioxatricyclo[9.2.1.04,8]tetradec-2-en-9-yl] 2-methylpropanoate 23255746 Drug sensitive Amsacrine 2179 Drug sensitive Pirarubicin hydrochloride 20846247 Drug sensitive 7,8-Dihydroxyflavone 1880 Drug sensitive Sudan II 18386 Drug sensitive 4-Chloro-5-phenoxy-3H-1,2-dithiole-3-thione 16766044 Drug sensitive Azaribine 16574 Drug sensitive (2Z,9E,13Z,15E)-4',11-Dihydroxy-2,4',9-trimethylspiro[3-aza-1(2,4)-thiazolacyclohexadecaphanene-6,3'-[1,2]dithiolane]-9,13,15-triene-4,5',12-trione 2'-oxide 154730760 Drug sensitive Methyl (3'R)-3,4',9',10-tetrahydroxy-3'-[(2S,4R,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-7'-methoxy-5',8',9-trioxospiro[3,4-dihydropyrano[4,3-g]chromene-2,2'-3H-benzo[f][1]benzofuran]-7-carboxylate 137326876 Drug sensitive C8, Carbonyl prodigiosine 135540857 Drug sensitive 5-[(E)-[Amino(methyl)amino]azo]-1H-imidazole-4-carboxamide 135493930 Drug sensitive Cysteine, S-[(4-aminocarbonyl-1H-imidazol-5-yl)azo]- 135493928 Drug sensitive Emofolin sodium 135475347 Drug sensitive 8-Azahypoxanthine 135410720 Drug sensitive Raltitrexed 135400182 Drug sensitive DTIC-Dome 135398738 Drug sensitive (2S,4S,5R)-20-De(1-hydroxypropyl)-6-demethyl-2,6-diethyl-5-hydroxy-20-(1-hydroxybutyl)lysocellin 124081057 Drug sensitive p-Toluquinone 11122 Drug sensitive Gentian violet 11057 Drug sensitive Withajardin C 102469053 Drug sensitive (7S,9S)-7-[[(3As,4S,7aS)-1-[[(3aS,4S,7aS)-4-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-2,3a,4,6,7,7a-hexahydropyrano[4,3-d][1,3]oxazol-1-yl]methyl]-4-methyl-2,3a,4,6,7,7a-hexahydropyrano[4,3-d][1,3]oxazol-6-yl]oxy]-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione 101713728 Drug sensitive (1S,2R,4R,6S,11R,12S,15R,18S,19R,20R,21S,23R,26R)-15-Hydroxy-11,18,21-trimethyl-5,17,24,28,29-pentaoxanonacyclo[17.9.1.11,20.02,12.04,6.06,11.015,19.018,23.021,26]triacont-8-ene-10,16,25,30-tetrone 101528280 Drug sensitive Erigerol 101318126 Drug sensitive [(1S,2S,4Z,8Z,12R,13S)-12-Hydroxy-4,8,12-trimethyl-16-methylidene-15-oxo-14-oxabicyclo[11.3.1]heptadeca-4,8-dien-2-yl] acetate 100921072 Drug sensitive Tocladesine 100299 Drug sensitive (1R,2E,6R,10E,11aS,13S,14aR)-6-(2-(benzyloxy)ethyl)-1,13-dihydroxy-6,7,8,9,12,13,14,14a-octahydro-1H-cyclopenta[f][1]oxacyclotridecin-4(11aH)-one - Drug resistant 2,3-dihydro-1,2-syn-3-[phenylseleno]brefeldin a - Drug resistant 9-methoxy-5-hydroxycamptothecin - Drug resistant tp4ek - Drug resistant (Z)-N-phenyl-3-(3,4,5-trimethoxystyryl)pyridin-2-amine - Drug sensitive 1,2-naphthoquinone, 3,7-dimethyl- - Drug sensitive 1h-benzimidazole, 5,5'-dithiobis[2-(trifluoromethyl)- (9ci) - Drug sensitive 2-[(3,4-dicloro)anilino]-3-phenyl-5,7-diamino quinoxaline - Drug sensitive 3',4',5'-trimethoxy-3-hydroxy flavone - Drug sensitive 4-(2-pyridinyl)-5h-1,2,3-dithiazole-5-thione - Drug sensitive 4-[3-(3,4-dihydro-1H-isoquinolin-2-yl)prop-1-en-2-yl]-N-pyrazin-2-ylbenzamide - Drug sensitive 4-quinazolone, 7-amino-3-(4-methoxyphenyl)-, hydrate - Drug sensitive 5.alpha.,25d-spirostan-3.beta.-ol glycoside - Drug sensitive 9h-quino[4,3,2-de][1,10]phenanthrolin-9-one, 5-methoxy- - Drug sensitive acetamide, n-(2-mercaptoethyl)-, benzoate (6ci, 7ci) - Drug sensitive b676297k277 3',4'-deoxypsorospermin 3',4'-chlorohydrin - Drug sensitive benzo[1,2-c:4,5-c']dipyrrole-1,3,5,7(2h,6h)-tetraimine - Drug sensitive benzofurazan, 4-nitro-7-(2-pyridinylthio)-, n-oxide - Drug sensitive bersaldegenin 1,3,5-orthoacetate - Drug sensitive cis-2-hydroxymethyl-4-(5'-bromocytosin-1'-yl)-1,3-dioxolane - Drug sensitive furan-2(3h)-one, 5-(4-methylphenyl)-3,3-diphenyl- - Drug sensitive isoflavone, 5,7-dihydroxy-4'-nitro- - Drug sensitive mercury, tetrakis(acetato)(2,3,4,5-thiophenetetrayl)tetra- - Drug sensitive n,n'-bis(oxydiethylene)thiocarbamoylsulfenamide - Drug sensitive phenol, 4,4'-(5,5'-biisoxazole-3,3'-diyl)bis- - Drug sensitive propan-1-one, 2,3-dichloro-1,3-bis(4-methylphenyl)- - Drug sensitive propanedinitrile, [(3,5-dibromo-2-ethoxyphenyl)methylene]- - Drug sensitive (Z)-3-((2-(4-(trifluoromethyl)phenyl)-3H-benzo[d]imidazol-5-yl)methylene)indolin-2-one - Drug sensitive [bis(aminomethyl)diethylsilane]dichloroplatinum (ii) - Drug sensitive 7-propanoyltaxol - Drug sensitive Aminopterin Derivative - Drug sensitive Annamycin Liposomal - Drug sensitive antineoplastic-d665839 - Drug sensitive Camptothecin Derivative - Drug sensitive Carboxyphthalatoplatinum - Drug sensitive chlorobis(4-ethyltropolonato)bismuth(iii) - Drug sensitive CI-921: amsacrine derivative - Drug sensitive Indenoisoquinoline derivative - Drug sensitive insulin-methotrexate conjugate - Drug sensitive merophan - Drug sensitive mitaplatin - Drug sensitive n-myristoyl-(s)-phenylalaninal diethylcetal - Drug sensitive organosulfur compound - Drug sensitive trimethyl(phenylthio)stannane - Drug sensitive

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-519e-3p	Alocrest 60780 Drug interaction    RC00005536 5-Fluorouracil 3385 Drug interaction    RC00005535 cis-Diaminedichloroplatinum 2767 Drug interaction    RC00005534 Tamoxifen 2733526 Drug interaction    RC00005537

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-519e-3p
Interactor2: RNF149

Evidence Support:

Weak-Evidence	RNA-Seq
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	31570108	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	ARPE-19 human RPE cells	Interactor2 expression	None
Description	Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).