Detail Information

Basic Information:


  VIRBase ID:  

HHID00005458

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-190a-5p:           C16orf87:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-190a-5p C16orf87
miRBase
Accession/Entrez ID		 MIMAT0000458 388272
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-190a-5p
rs1018706777 chr15:62823984    A/G
rs1369926402 chr15:62823991    G/A
rs1555521311 chr15:62823990    G/C
rs755866868 chr15:62823986    A/G
rs766742872 chr15:62823990    GGTT/G
rs777464613 chr15:62823987    T/G
rs1228899174 chr15:62823974    T/A
rs1281303771 chr15:62823976    T/C
rs1350000299 chr15:62823972    G/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR C16orf87
chr16:46853778(-) A-I      intronic
chr16:46843197(-) A-I      intronic
chr16:46845271(-) A-I      intronic
chr16:46845289(-) A-I      intronic
chr16:46852061(-) A-I      intronic
chr16:46841150(-) A-I      intronic
chr16:46853724(-) A-I      intronic
chr16:46841260(-) A-I      intronic
chr16:46853223(-) A-I      intronic
chr16:46840275(-) A-I      intronic
chr16:46841184(-) A-I      intronic
chr16:46840350(-) A-I      intronic
chr16:46853248(-) A-I      intronic
chr16:46853770(-) A-I      intronic
chr16:46840200(-) A-I      intronic
chr16:46840376(-) A-I      intronic
chr16:46851340(-) A-I      intronic
chr16:46840438(-) A-I      intronic
chr16:46853300(-) A-I      intronic
chr16:46841315(-) A-I      intronic
chr16:46853799(-) A-I      intronic
chr16:46840399(-) A-I      intronic
chr16:46841185(-) A-I      intronic
chr16:46840443(-) A-I      intronic
chr16:46840351(-) A-I      intronic
chr16:46853277(-) A-I      intronic
chr16:46861985(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase C16orf87
chr16:46835794-46835795(-) m6A 3'UTR       27773535
chr16:46835959-46835960(-) m6A 3'UTR       27773535
chr16:46835973-46835974(-) m6A 3'UTR       27773535
chr16:46836339-46836340(-) m6A 3'UTR       27773535
chr16:46836533-46836534(-) m6A 3'UTR       24981863//27773535//22608085
chr16:46836598-46836599(-) m6A 3'UTR       24284625//24209618//24981863//28052920//27773535//22608085
chr16:46836689-46836690(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr16:46836795-46836796(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr16:46836805-46836806(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr16:46836838-46836839(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr16:46836875-46836876(-) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr16:46836977-46836978(-) m6A 3'UTR//CDS//exon       24284625//24981863//27773535//22608085
chr16:46841940-46841941(-) m6A CDS//intron       24981863//27773535//22608085
chr16:46842002-46842003(-) m6A CDS//intron       24981863//27773535//22608085
chr16:46842022-46842023(-) m6A CDS//intron       24981863//27773535//22608085
chr16:46842035-46842036(-) m6A CDS//intron       24981863//27773535//22608085
chr16:46843530-46843531(-) m6A CDS//exon//intron       24981863//27773535//22608085
chr16:46843554-46843555(-) m6A CDS//exon//intron       24284625//24981863//27773535//22608085
chr16:46843612-46843613(-) m6A CDS//exon//intron       24284625//24981863//27773535//22608085
chr16:46843667-46843668(-) m6A CDS//exon//intron       24284625//24981863//27773535//22608085
chr16:46843693-46843694(-) m6A CDS//exon//intron       24284625//24981863//27773535//22608085
chr16:46858325-46858326(-) m6A CDS//exon       24981863//27773535//22608085
chr16:46858340-46858341(-) m6A CDS//exon       24981863//27773535
chr16:46864588-46864589(-) m6A exon//intron       27773535
chr16:46865143-46865144(-) m6A 5'UTR       24981863//27371828

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-190a-5p
Exosome Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Plasma     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901
Microvesicle Colon cancer cell line (LIM1863)|Mesenchymal stem cells|Urine     -
C16orf87
Chromatin K562 cells     -
Exosome Blood     -
Membrane HCC cell line (HepG2)     -
Nucleoplasm K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-190a-5p
Interactor2: C16orf87

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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