Detail Information

Basic Information:


  VIRBase ID:  

HHID00005408

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.6002

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-190a-5p:           KCTD1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-190a-5p KCTD1
miRBase
Accession/Entrez ID		 MIMAT0000458 284252
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - C18orf5

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-190a-5p
rs1018706777 chr15:62823984    A/G
rs1369926402 chr15:62823991    G/A
rs1555521311 chr15:62823990    G/C
rs755866868 chr15:62823986    A/G
rs766742872 chr15:62823990    GGTT/G
rs777464613 chr15:62823987    T/G
rs1228899174 chr15:62823974    T/A
rs1281303771 chr15:62823976    T/C
rs1350000299 chr15:62823972    G/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR KCTD1
chr18:24179324(-) A-I      intronic
chr18:24179327(-) A-I      intronic
chr18:24179333(-) A-I      intronic
chr18:24179347(-) A-I      intronic
chr18:24179281(-) A-I      intronic
chr18:24179309(-) A-I      intronic
chr18:24179318(-) A-I      intronic
chr18:24097499(-) A-I      intronic
chr18:24098363(-) A-I      intronic
chr18:24092244(-) A-I      intronic
chr18:24097497(-) A-I      intronic
chr18:24097473(-) A-I      intronic
chr18:24097464(-) A-I      intronic
chr18:24113578(-) A-I      intronic
chr18:24094386(-) A-I      intronic
chr18:24094299(-) A-I      intronic
chr18:24094296(-) A-I      intronic
chr18:24094260(-) A-I      intronic
chr18:24092821(-) A-I      intronic
chr18:24098479(-) A-I      intronic
chr18:24092183(-) A-I      intronic
chr18:24049850(-) A-I      intronic
chr18:24049869(-) A-I      intronic
chr18:24070894(-) A-I      intronic
chr18:24070896(-) A-I      intronic
chr18:24084442(-) A-I      intronic
chr18:24085978(-) A-I      intronic
chr18:24086125(-) A-I      intronic
chr18:24111238(-) A-I      intronic
chr18:24191459(-) A-I      intronic
chr18:24113743(-) A-I      intronic
chr18:24092788(-) A-I      intronic
chr18:24161494(-) A-I      intronic
chr18:24098495(-) A-I      intronic
chr18:24092782(-) A-I      intronic
chr18:24191362(-) A-I      intronic
chr18:24201069(-) A-I      intronic
chr18:24092719(-) A-I      intronic
chr18:24092245(-) A-I      intronic
chr18:24098400(-) A-I      intronic
chr18:24177835(-) A-I      intronic
chr18:24097376(-) A-I      intronic
chr18:24094483(-) A-I      intronic
chr18:24043202(-) A-I      intronic
chr18:24092700(-) A-I      intronic
chr18:24086072(-) A-I      intronic
chr18:24086045(-) A-I      intronic
chr18:24191452(-) A-I      intronic
chr18:24118128(-) A-I      intronic
chr18:24206598(-) A-I      intronic
chr18:24177755(-) A-I      intronic
chr18:24087543(-) A-I      intronic
chr18:24177633(-) A-I      intronic
chr18:24144729(-) A-I      intronic
chr18:24085945(-) A-I      intronic
chr18:24170145(-) A-I      intronic
chr18:24043616(-) A-I      intronic
chr18:24147453(-) A-I      intronic
chr18:24133162(-) A-I      intronic
chr18:24085947(-) A-I      intronic
chr18:24177769(-) A-I      intronic
chr18:24148396(-) A-I      intronic
chr18:24084481(-) A-I      intronic
chr18:24103532(-) A-I      intronic
chr18:24043199(-) A-I      intronic
chr18:24150648(-) A-I      intronic
chr18:24092178(-) A-I      intronic
chr18:24094462(-) A-I      intronic
chr18:24045290(-) A-I      intronic
chr18:24177864(-) A-I      intronic
chr18:24092876(-) A-I      intronic
chr18:24092845(-) A-I      intronic
chr18:24162113(-) A-I      intronic
chr18:24144609(-) A-I      intronic
chr18:24092893(-) A-I      intronic
chr18:24043335(-) A-I      intronic
chr18:24092823(-) A-I      intronic
chr18:24092862(-) A-I      intronic
chr18:24087539(-) A-I      intronic
chr18:24087394(-) A-I      intronic
chr18:24111206(-) A-I      intronic
chr18:24196622(-) A-I      intronic
chr18:24094345(-) A-I      intronic
chr18:24210574(-) A-I      intronic
chr18:24087410(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED KCTD1
chr18:24085722(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase KCTD1
chr18:24034954-24034955(-) m6A 3'UTR       27773535
chr18:24035011-24035012(-) Y 3'UTR       26075521
chr18:24035065-24035066(-) m6A 3'UTR       27773535
chr18:24035083-24035084(-) m6A 3'UTR       27773535
chr18:24035542-24035543(-) m6A 3'UTR       24284625//24981863//27773535//22608085
chr18:24035565-24035566(-) m6A 3'UTR       24284625//25456834//24981863//27773535//22575960//22608085
chr18:24035586-24035587(-) m6A 3'UTR       24284625//25456834//24981863//27773535//22575960//22608085
chr18:24035617-24035618(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr18:24035624-24035625(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr18:24035643-24035644(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr18:24035654-24035655(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr18:24035676-24035677(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr18:24035701-24035702(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr18:24035710-24035711(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr18:24035766-24035767(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr18:24035803-24035804(-) m6A CDS//exon       24284625//25456834//24981863//22575960//22608085
chr18:24056845-24056846(-) m6A exon//intron       27773535
chr18:24081155-24081156(-) m6A CDS       24284625//24981863//27773535
chr18:24081190-24081191(-) m6A CDS       24284625//24981863//27773535//22608085
chr18:24126784-24126785(-) m6A 5'UTR//intron       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr18:24126838-24126839(-) m6A 5'UTR//intron       24284625//24209618//25456834//24981863//27371828//22575960//22608085
chr18:24126944-24126945(-) m6A 5'UTR//intron       24284625//24209618//25456834//24981863//22608085
chr18:24126965-24126966(-) m6A 5'UTR//intron       24284625//24209618//25456834//24981863//22608085
chr18:24127161-24127162(-) m6A intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//27773536//22575960//22608085
chr18:24127214-24127215(-) m6A intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//27773536//22575960//22608085
chr18:24127232-24127233(-) m6A intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//27773536//22575960//22608085
chr18:24127268-24127269(-) m6A intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//27773536//22575960//22608085
chr18:24127379-24127380(-) m6A intron       24284625//25456834//24981863//27371828//22575960//22608085
chr18:24127505-24127506(-) m6A intron       24284625//25456834//24981863//27371828//22575960//22608085
chr18:24127526-24127527(-) m6A intron       24284625//25456834//24981863//27371828//22608085
chr18:24127742-24127743(-) m6A intron       24284625//27371828//22608085
chr18:24127901-24127902(-) m6A intron       24284625//25456834//24981863//27371828//22575960//22608085
chr18:24127908-24127909(-) m6A intron       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085
chr18:24127916-24127917(-) m6A intron       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085
chr18:24127988-24127989(-) m6A intron       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085
chr18:24128033-24128034(-) m6A intron       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085
chr18:24128123-24128124(-) m6A intron       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085
chr18:24128174-24128175(-) m6A intron       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085
chr18:24128201-24128202(-) m6A intron       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085
chr18:24128420-24128421(-) m6A intron       25456834//24981863//27371828//22575960//22608085
chr18:24128474-24128475(-) m6A intron       24284625//25456834//24981863//27371828//22575960//22608085
chr18:24128919-24128920(-) m6A 5'UTR//intron       24284625//25456834//24981863
chr18:24129373-24129374(-) m6A 5'UTR//intron       24981863
chr18:24129384-24129385(-) m6A 5'UTR//intron       24981863
chr18:24129394-24129395(-) m6A 5'UTR//intron       24981863
chr18:24129698-24129699(-) m6A 5'UTR//intron       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-190a-5p
Exosome Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Plasma     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901
Microvesicle Colon cancer cell line (LIM1863)|Mesenchymal stem cells|Urine     -
KCTD1
Exosome Blood     -
Nucleus HCC cell line (HepG2)|HeLa-S3 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-190a-5p
Interactor2: KCTD1

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence DIANA-microT//miRDB//Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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