Detail Information

Basic Information:


  VIRBase ID:  

HHID00005329

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.6002

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-190a-5p:           TXLNB:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-190a-5p TXLNB
miRBase
Accession/Entrez ID		 MIMAT0000458 167838
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - C6orf198//dJ522B19.2//LST001//MDP77

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-190a-5p
rs1018706777 chr15:62823984    A/G
rs1369926402 chr15:62823991    G/A
rs1555521311 chr15:62823990    G/C
rs755866868 chr15:62823986    A/G
rs766742872 chr15:62823990    GGTT/G
rs777464613 chr15:62823987    T/G
rs1228899174 chr15:62823974    T/A
rs1281303771 chr15:62823976    T/C
rs1350000299 chr15:62823972    G/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR TXLNB
chr6:139589204(-) A-I      intronic
chr6:139589171(-) A-I      intronic
chr6:139589201(-) A-I      intronic
chr6:139589176(-) A-I      intronic
chr6:139589170(-) A-I      intronic
chr6:139581230(-) A-I      intronic
chr6:139581289(-) A-I      intronic
chr6:139594014(-) A-I      intronic
chr6:139594726(-) A-I      intronic
chr6:139568506(-) A-I      intronic
chr6:139574077(-) A-I      intronic
chr6:139576979(-) A-I      intronic
chr6:139594889(-) A-I      intronic
chr6:139577470(-) A-I      intronic
chr6:139577527(-) A-I      intronic
chr6:139577534(-) A-I      intronic
chr6:139577668(-) A-I      intronic
chr6:139577740(-) A-I      intronic
chr6:139577756(-) A-I      intronic
chr6:139594890(-) A-I      intronic
chr6:139605602(-) A-I      intronic
chr6:139605605(-) A-I      intronic
chr6:139567964(-) A-I      intronic
chr6:139581101(-) A-I      intronic
chr6:139567965(-) A-I      intronic
chr6:139567951(-) A-I      intronic
chr6:139567968(-) A-I      intronic
chr6:139567969(-) A-I      intronic
chr6:139571377(-) A-I      intronic
chr6:139568327(-) A-I      intronic
chr6:139568342(-) A-I      intronic
chr6:139569430(-) A-I      intronic
chr6:139571284(-) A-I      intronic
chr6:139569439(-) A-I      intronic
chr6:139577559(-) A-I      intronic
chr6:139577563(-) A-I      intronic
chr6:139581188(-) A-I      intronic
chr6:139581180(-) A-I      intronic
chr6:139590110(-) A-I      intronic
chr6:139568461(-) A-I      intronic
chr6:139568482(-) A-I      intronic
chr6:139581351(-) A-I      intronic
chr6:139567013(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED TXLNB
chr6:139568461(-) A-G intron -    22484847
chr6:139577559(-) A-G intron -    22484847
chr6:139581180(-) A-G intron -    22484847
chr6:139581203(-) A-G intron -    22484847
chr6:139581250(-) A-G intron -    22484847
chr6:139581351(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase TXLNB
chr6:139564150-139564151(-) m6A CDS       27773535
chr6:139564225-139564226(-) m6A CDS       27773535
chr6:139564358-139564359(-) m6A CDS       27773535//22608085
chr6:139564392-139564393(-) m6A CDS       27773535//22608085
chr6:139565744-139565745(-) m6A CDS       -
chr6:139565765-139565766(-) m6A CDS       -
chr6:139568957-139568958(-) m6A CDS       27773535
chr6:139568968-139568969(-) m6A CDS       27773535
chr6:139581544-139581545(-) m6A CDS       27773535
chr6:139581553-139581554(-) m6A CDS       27773535
chr6:139581566-139581567(-) m6A CDS       27773535
chr6:139583773-139583774(-) m6A CDS       27773535
chr6:139583830-139583831(-) m6A CDS       27773535
chr6:139591600-139591601(-) m6A CDS       -
chr6:139591610-139591611(-) m6A CDS       -
chr6:139609700-139609701(-) m6A CDS       27773535
chr6:139609723-139609724(-) m6A CDS       27773535//22608085
chr6:139609734-139609735(-) m6A CDS       27773535//22608085
chr6:139609842-139609843(-) m6A CDS       -
chr6:139610015-139610016(-) m6A CDS       27773535

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-190a-5p
Exosome Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Plasma     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901
Microvesicle Colon cancer cell line (LIM1863)|Mesenchymal stem cells|Urine     -
TXLNB
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-190a-5p
Interactor2: TXLNB

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence DIANA-microT//miRDB//Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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