Detail Information

Basic Information:


  VIRBase ID:  

HHID00005250

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.6002

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-190a-5p:           AMER1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-190a-5p AMER1
miRBase
Accession/Entrez ID		 MIMAT0000458 139285
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - FAM123B//OSCS//WTX

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-190a-5p
rs1018706777 chr15:62823984    A/G
rs1369926402 chr15:62823991    G/A
rs1555521311 chr15:62823990    G/C
rs755866868 chr15:62823986    A/G
rs766742872 chr15:62823990    GGTT/G
rs777464613 chr15:62823987    T/G
rs1228899174 chr15:62823974    T/A
rs1281303771 chr15:62823976    T/C
rs1350000299 chr15:62823972    G/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR AMER1
chrX:63421897(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase AMER1
chrX:63405143-63405144(-) m6A 3'UTR       24284625
chrX:63405249-63405250(-) m6A 3'UTR       24284625
chrX:63407465-63407466(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chrX:63407510-63407511(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chrX:63407563-63407564(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//22608085
chrX:63407595-63407596(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22608085
chrX:63407808-63407809(-) m6A 3'UTR//intron       24284625//25456834//24981863//22608085
chrX:63407814-63407815(-) m6A 3'UTR//intron       24284625//25456834
chrX:63407887-63407888(-) m6A 3'UTR//intron       -
chrX:63408474-63408475(-) m6A 3'UTR//intron       24284625
chrX:63408754-63408755(-) m6A 3'UTR//intron       -
chrX:63409254-63409255(-) m6A 3'UTR//intron       -
chrX:63409295-63409296(-) m6A 3'UTR//intron       -
chrX:63409342-63409343(-) m6A 3'UTR//intron       24981863
chrX:63409734-63409735(-) m6A 3'UTR//intron       24284625
chrX:63409771-63409772(-) m6A CDS//intron       24284625
chrX:63410224-63410225(-) m6A CDS//intron       24284625//24209618//24981863//27773535
chrX:63410313-63410314(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27371828//22608085
chrX:63410338-63410339(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27371828//22608085
chrX:63410465-63410466(-) m6A CDS//intron       24284625//25456834//24981863//27371828//22575960//22608085
chrX:63410544-63410545(-) m6A CDS//intron       24284625//22608085
chrX:63410622-63410623(-) m6A CDS//intron       24284625//24209618
chrX:63410770-63410771(-) m6A CDS//intron       24284625//24981863//27371828//22608085
chrX:63410824-63410825(-) m6A CDS       24284625//24981863//27371828//27773536//22608085
chrX:63410974-63410975(-) m6A CDS       -
chrX:63411044-63411045(-) m6A CDS       24284625//24981863
chrX:63411076-63411077(-) m6A CDS       24284625//24209618//24981863//22608085
chrX:63411085-63411086(-) m6A CDS       24284625//24209618//24981863//22608085
chrX:63411149-63411150(-) m6A CDS       24284625//24209618//25456834//24981863//22608085
chrX:63411239-63411240(-) m6A CDS       24284625//24209618//25456834//24981863//27371828//22608085
chrX:63411254-63411255(-) m6A CDS       24284625//24209618//25456834//24981863//27371828//22608085
chrX:63411293-63411294(-) m6A CDS       24284625//24209618//24981863//27371828//22608085
chrX:63411468-63411469(-) m6A CDS       24284625
chrX:63411500-63411501(-) m6A CDS       24284625//24981863//22608085
chrX:63411544-63411545(-) m6A CDS       24284625//24981863//22608085
chrX:63411616-63411617(-) m6A CDS       24284625//24209618//24981863//22608085
chrX:63411673-63411674(-) m6A CDS       24284625//24209618//24981863//22608085
chrX:63411810-63411811(-) m6A CDS       24284625//22575960//22608085
chrX:63411901-63411902(-) m6A CDS       24284625//24981863//27773535//22608085
chrX:63411932-63411933(-) m6A CDS       24284625//24981863//27773535//22608085
chrX:63411961-63411962(-) m1A CDS       26863196
chrX:63411985-63411986(-) m1A CDS       26863196
chrX:63412009-63412010(-) m1A CDS       26863196
chrX:63412018-63412019(-) m1A CDS       26863196
chrX:63412100-63412101(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chrX:63412111-63412112(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chrX:63412141-63412142(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chrX:63412153-63412154(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chrX:63412159-63412160(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chrX:63412164-63412165(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chrX:63412246-63412247(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chrX:63412270-63412271(-) m6A CDS       24284625//24981863//27773535//22608085
chrX:63412301-63412302(-) m6A CDS       24284625//24981863//27773535//22608085
chrX:63412386-63412387(-) m6A CDS       24284625//24981863//27773535
chrX:63412434-63412435(-) m6A CDS       24284625//27371828
chrX:63412508-63412509(-) m6A CDS       24284625//27371828
chrX:63412733-63412734(-) m6A CDS       22608085
chrX:63412751-63412752(-) m6A CDS       24284625//22608085
chrX:63412826-63412827(-) m6A CDS       24284625//24209618//25456834//22608085
chrX:63412883-63412884(-) m6A CDS       24284625//24209618//25456834//24981863//22608085
chrX:63412992-63412993(-) m6A CDS       24284625//25456834//24981863//27371828//22608085
chrX:63413003-63413004(-) m6A CDS       24284625//25456834//24981863//27371828//22608085
chrX:63413049-63413050(-) m6A CDS       24284625//24981863//27371828//22608085
chrX:63413074-63413075(-) m6A CDS       24284625//24981863//27371828//22608085
chrX:63413100-63413101(-) m6A CDS       24284625//24981863//27371828//22608085
chrX:63413159-63413160(-) m6A CDS       24284625//27773535
chrX:63425463-63425464(-) m6A 5'UTR       27371828
chrX:63425481-63425482(-) m6A 5'UTR       27371828

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-190a-5p
Exosome Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Plasma     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901
Microvesicle Colon cancer cell line (LIM1863)|Mesenchymal stem cells|Urine     -
AMER1
Exosome Blood     -
Nucleus HeLa-S3 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-190a-5p
Interactor2: AMER1

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence DIANA-microT//miRDB//Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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