Detail Information

Basic Information:


  VIRBase ID:  

HHID00005128

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.6002

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-190a-5p:           UTP23:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-190a-5p UTP23
miRBase
Accession/Entrez ID		 MIMAT0000458 84294
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - C8orf53

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-190a-5p
rs1018706777 chr15:62823984    A/G
rs1369926402 chr15:62823991    G/A
rs1555521311 chr15:62823990    G/C
rs755866868 chr15:62823986    A/G
rs766742872 chr15:62823990    GGTT/G
rs777464613 chr15:62823987    T/G
rs1228899174 chr15:62823974    T/A
rs1281303771 chr15:62823976    T/C
rs1350000299 chr15:62823972    G/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR UTP23
chr8:117804840(+) A-I      intronic
chr8:117800585(+) A-I      intronic
chr8:117800550(+) A-I      intronic
chr8:117781139(+) A-I      intronic
chr8:117825237(+) A-I      intronic
chr8:117800618(+) A-I      intronic
chr8:117809285(+) A-I      intronic
chr8:117792944(+) A-I      intronic
chr8:117780180(+) A-I      intronic
chr8:117800624(+) A-I      intronic
chr8:117788467(+) A-I      intronic
chr8:117851469(+) A-I      intronic
chr8:117794194(+) A-I      intronic
chr8:117839956(+) A-I      intronic
chr8:117838159(+) A-I      intronic
chr8:117794102(+) A-I      intronic
chr8:117839148(+) A-I      intronic
chr8:117842779(+) A-I      intronic
chr8:117800488(+) A-I      intronic
chr8:117780185(+) A-I      intronic
chr8:117825165(+) A-I      intronic
chr8:117803161(+) A-I      intronic
chr8:117826967(+) A-I      intronic
chr8:117781178(+) A-I      intronic
chr8:117800551(+) A-I      intronic
chr8:117800678(+) A-I      intronic
chr8:117788517(+) A-I      intronic
chr8:117799884(+) A-I      intronic
chr8:117787199(+) A-I      intronic
chr8:117788924(+) A-I      intronic
chr8:117782959(+) A-I      intronic
chr8:117804977(+) A-I      intronic
chr8:117800538(+) A-I      intronic
chr8:117794244(+) A-I      intronic
chr8:117850535(+) A-I      intronic
chr8:117800473(+) A-I      intronic
chr8:117804911(+) A-I      intronic
chr8:117794870(+) A-I      intronic
chr8:117782914(+) A-I      intronic
chr8:117839115(+) A-I      intronic
chr8:117839291(+) A-I      intronic
chr8:117788401(+) A-I      intronic
chr8:117794182(+) A-I      intronic
chr8:117794116(+) A-I      intronic
chr8:117851488(+) A-I      intronic
chr8:117839195(+) A-I      intronic
chr8:117794112(+) A-I      intronic
chr8:117793032(+) A-I      intronic
chr8:117794828(+) A-I      intronic
chr8:117825164(+) A-I      intronic
chr8:117780232(+) A-I      intronic
chr8:117792866(+) A-I      intronic
chr8:117850548(+) A-I      intronic
chr8:117794062(+) A-I      intronic
chr8:117799887(+) A-I      intronic
chr8:117845142(+) A-I      intronic
chr8:117800527(+) A-I      intronic
chr8:117793087(+) A-I      intronic
chr8:117800487(+) A-I      intronic
chr8:117794044(+) A-I      intronic
chr8:117800541(+) A-I      intronic
chr8:117780279(+) A-I      intronic
chr8:117792909(+) A-I      intronic
chr8:117794183(+) A-I      intronic
chr8:117794923(+) A-I      intronic
chr8:117823635(+) A-I      intronic
chr8:117806073(+) A-I      intronic
chr8:117805945(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED UTP23
chr8:117780185(+) A-G intron -    22484847
chr8:117784241(+) G-A intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase UTP23
chr8:117778759-117778760(+) m6A 5'UTR       24981863
chr8:117778862-117778863(+) m6A CDS//exon       24981863
chr8:117782393-117782394(+) m6A exon//intron       24981863
chr8:117783758-117783759(+) m6A CDS//exon//intron       24284625//24209618//24981863//27773535//22608085
chr8:117783773-117783774(+) m6A CDS//exon//intron       24284625//24209618//24981863//27773535//22608085
chr8:117783790-117783791(+) m6A CDS//exon//intron       24284625//24209618//24981863//27773535//22608085
chr8:117783858-117783859(+) m6A CDS//exon//intron       24284625//24209618//24981863//27773535//22608085
chr8:117783873-117783874(+) m6A CDS//exon//intron       24284625//24209618//24981863//27773535//22608085
chr8:117783890-117783891(+) m6A CDS//exon//intron       24284625//24209618//24981863//27773535//22608085
chr8:117783897-117783898(+) m6A CDS//exon//intron       24284625//24209618//24981863//27773535//22608085
chr8:117783977-117783978(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr8:117784028-117784029(+) m6A CDS//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr8:117784102-117784103(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr8:117784155-117784156(+) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr8:117784160-117784161(+) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr8:117784178-117784179(+) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr8:117784216-117784217(+) m6A 3'UTR//intron       24981863//22608085
chr8:117784245-117784246(+) m6A 3'UTR//intron       24981863//22608085
chr8:117798868-117798869(+) m6A 3'UTR//intron       22608085
chr8:117798912-117798913(+) m6A 3'UTR//intron       22608085
chr8:117861129-117861130(+) m6A 3'UTR//CDS       22608085
chr8:117861168-117861169(+) m6A 3'UTR//CDS       25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr8:117861190-117861191(+) m6A 3'UTR//CDS       25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr8:117861301-117861302(+) m6A 3'UTR       25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr8:117861376-117861377(+) m6A 3'UTR       27773535//27371828
chr8:117861387-117861388(+) m6A 3'UTR       27773535//27371828

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-190a-5p
Exosome Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Plasma     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901
Microvesicle Colon cancer cell line (LIM1863)|Mesenchymal stem cells|Urine     -
UTP23
Chromatin K562 cells     -
Cytosol K562 cells     -
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-190a-5p
Interactor2: UTP23

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence DIANA-microT//miRDB//Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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