Basic Information:

  VIRBase ID:  

HHID00004603

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-190a-5p:  MIMAT0000458          FUT9:  NM_006581     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-190a-5p	FUT9
miRBase Accession/Entrez ID	MIMAT0000458	10690
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	Fuc-TIX

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-190a-5p	rs1018706777 chr15:62823984    A/G rs1369926402 chr15:62823991    G/A rs1555521311 chr15:62823990    G/C rs755866868 chr15:62823986    A/G rs766742872 chr15:62823990    GGTT/G rs777464613 chr15:62823987    T/G rs1228899174 chr15:62823974    T/A rs1281303771 chr15:62823976    T/C rs1350000299 chr15:62823972    G/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	FUT9	chr6:96606883(+) A-I      intronic chr6:96606884(+) A-I      intronic chr6:96606885(+) A-I      intronic chr6:96606895(+) A-I      intronic chr6:96606845(+) A-I      intronic chr6:96606856(+) A-I      intronic chr6:96606858(+) A-I      intronic chr6:96606898(+) A-I      intronic chr6:96607021(+) A-I      intronic chr6:96607045(+) A-I      intronic chr6:96607048(+) A-I      intronic chr6:96607049(+) A-I      intronic chr6:96607079(+) A-I      intronic chr6:96607085(+) A-I      intronic chr6:96607086(+) A-I      intronic chr6:96607053(+) A-I      intronic chr6:96613118(+) A-I      intronic chr6:96561525(+) A-I      intronic chr6:96613727(+) A-I      intronic chr6:96613672(+) A-I      intronic chr6:96613631(+) A-I      intronic chr6:96521227(+) A-I      intronic chr6:96570881(+) A-I      intronic chr6:96572157(+) A-I      intronic chr6:96593818(+) A-I      intronic chr6:96612274(+) A-I      intronic chr6:96526487(+) A-I      intronic chr6:96613543(+) A-I      intronic chr6:96521178(+) A-I      intronic chr6:96517689(+) A-I      intronic chr6:96570734(+) A-I      intronic chr6:96613745(+) A-I      intronic chr6:96549594(+) A-I      intronic chr6:96613152(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	FUT9	chr6:96651123-96651124(+) m6A CDS       24981863 chr6:96651185-96651186(+) m6A CDS       24981863//22575960 chr6:96651202-96651203(+) m6A CDS       24981863//22575960 chr6:96651220-96651221(+) m6A CDS       24981863//22575960 chr6:96651256-96651257(+) m6A CDS       24981863//22575960 chr6:96651317-96651318(+) m6A CDS       24981863//22575960 chr6:96651365-96651366(+) m6A CDS       24981863//22575960 chr6:96651620-96651621(+) m6A CDS       24981863 chr6:96651843-96651844(+) m6A CDS       24981863//22608085 chr6:96651857-96651858(+) m6A CDS       24981863//22608085 chr6:96651953-96651954(+) m6A CDS       24981863//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-190a-5p	Exosome Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901 Exosome Brain tissue     23382797 Exosome Plasma     23663360 Exosome Plasma     24683445 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901 Microvesicle Colon cancer cell line (LIM1863)|Mesenchymal stem cells|Urine     -
	FUT9	Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-190a-5p
Interactor2: FUT9

Evidence Support:

Weak-Evidence	RNA-Seq
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	31570108	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	ARPE-19 human RPE cells	Interactor2 expression	None
Description	Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).