Detail Information

Basic Information:


  VIRBase ID:  

HHID00003981

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-190a-5p:           AR:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-190a-5p AR
miRBase
Accession/Entrez ID		 MIMAT0000458 367
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - AIS//AR8//DHTR//HUMARA//HYSP1//KD//NR3C4//SBMA//SMAX1//TFM

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-190a-5p
rs1018706777 chr15:62823984    A/G
rs1369926402 chr15:62823991    G/A
rs1555521311 chr15:62823990    G/C
rs755866868 chr15:62823986    A/G
rs766742872 chr15:62823990    GGTT/G
rs777464613 chr15:62823987    T/G
rs1228899174 chr15:62823974    T/A
rs1281303771 chr15:62823976    T/C
rs1350000299 chr15:62823972    G/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR AR
chrX:66814064(+) A-I      intronic
chrX:66814056(+) A-I      intronic
chrX:66815549(+) A-I      intronic
chrX:66815552(+) A-I      intronic
chrX:66814670(+) A-I      intronic
chrX:66814660(+) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase AR
chrX:66764122-66764123(+) m6A 5'UTR       -
chrX:66764154-66764155(+) m6A 5'UTR       -
chrX:66764473-66764474(+) m6A 5'UTR       24284625
chrX:66764583-66764584(+) m6A 5'UTR       24284625//24981863
chrX:66764588-66764589(+) m6A 5'UTR       24284625//24981863
chrX:66764598-66764599(+) m6A 5'UTR       24284625//24981863
chrX:66764662-66764663(+) m6A 5'UTR//exon       24284625//24981863
chrX:66764746-66764747(+) m6A 5'UTR//exon       24284625//25456834//24981863
chrX:66764804-66764805(+) m6A 5'UTR//exon       24284625//25456834//24981863
chrX:66764920-66764921(+) m6A 5'UTR//exon       24284625//25456834//24981863
chrX:66765039-66765040(+) m6A 5'UTR//CDS//exon       24284625
chrX:66765094-66765095(+) m6A 5'UTR//CDS//exon       24284625
chrX:66765231-66765232(+) m6A 5'UTR//CDS//exon       24284625
chrX:66765326-66765327(+) m6A 5'UTR//CDS//exon       24284625
chrX:66765535-66765536(+) m6A 5'UTR//CDS//exon       24284625//24981863
chrX:66765655-66765656(+) m6A CDS//exon       24284625//24981863
chrX:66765770-66765771(+) m6A CDS//exon       24284625//24981863
chrX:66765999-66766000(+) m6A CDS//exon       24284625//24209618//25456834//24981863
chrX:66766007-66766008(+) m6A CDS//exon       24284625//24209618//25456834//24981863
chrX:66766106-66766107(+) m6A CDS//exon       24284625//24209618//25456834//24981863
chrX:66766159-66766160(+) m6A CDS//exon       24284625//24209618//25456834//24981863
chrX:66766168-66766169(+) m6A CDS//exon       24284625//24209618//25456834//24981863
chrX:66766216-66766217(+) m6A CDS//exon       25456834//24981863
chrX:66766250-66766251(+) m6A CDS//exon       25456834//24981863
chrX:66766315-66766316(+) m1A CDS//exon       26863196
chrX:66766331-66766332(+) m6A CDS//exon       25456834//24981863
chrX:66766586-66766587(+) m6A CDS//exon       24284625
chrX:66766597-66766598(+) m6A CDS//exon       24284625
chrX:66944117-66944118(+) m6A 3'UTR       24981863
chrX:66944136-66944137(+) m6A 3'UTR       24981863
chrX:66944141-66944142(+) m6A 3'UTR       24981863
chrX:66944160-66944161(+) m6A 3'UTR       24981863
chrX:66944564-66944565(+) m6A 3'UTR       24981863
chrX:66944625-66944626(+) m6A 3'UTR       24284625//24981863
chrX:66944633-66944634(+) m6A 3'UTR       24284625//24981863
chrX:66944656-66944657(+) m6A 3'UTR       24284625//24981863
chrX:66944824-66944825(+) m6A 3'UTR       24284625//24209618//25456834//24981863
chrX:66944843-66944844(+) m6A 3'UTR       24284625//24209618//25456834//24981863
chrX:66944880-66944881(+) m6A 3'UTR       24284625//25456834//24981863
chrX:66944903-66944904(+) m6A 3'UTR       24284625//25456834//24981863
chrX:66945145-66945146(+) m6A 3'UTR       24981863
chrX:66945296-66945297(+) m6A 3'UTR       24284625//24981863
chrX:66945333-66945334(+) m6A 3'UTR       24284625//24981863
chrX:66945340-66945341(+) m6A 3'UTR       24284625//24981863
chrX:66945406-66945407(+) m6A 3'UTR       24284625//24981863
chrX:66945417-66945418(+) m6A 3'UTR       24284625//24981863
chrX:66945468-66945469(+) m6A 3'UTR       24284625//24981863
chrX:66945587-66945588(+) m6A 3'UTR       24284625//24981863
chrX:66945596-66945597(+) m6A 3'UTR       24284625//24981863
chrX:66945608-66945609(+) m6A 3'UTR       24284625//24981863
chrX:66945667-66945668(+) m6A 3'UTR       24284625//24981863
chrX:66945686-66945687(+) m6A 3'UTR       24284625//24981863
chrX:66945825-66945826(+) m6A 3'UTR       24284625//24981863
chrX:66945969-66945970(+) m6A 3'UTR       24284625//24981863
chrX:66945977-66945978(+) m6A 3'UTR       24284625//24981863
chrX:66946005-66946006(+) m6A 3'UTR       24284625//24981863
chrX:66946034-66946035(+) m6A 3'UTR       24284625//24981863
chrX:66946047-66946048(+) m6A 3'UTR       24284625//24981863
chrX:66946084-66946085(+) m6A 3'UTR       24284625//24981863
chrX:66946464-66946465(+) m6A 3'UTR       24981863
chrX:66946527-66946528(+) m6A 3'UTR       24981863
chrX:66946659-66946660(+) m6A 3'UTR       24284625//24981863
chrX:66946701-66946702(+) m6A 3'UTR       24284625//24981863
chrX:66946714-66946715(+) m6A 3'UTR       24284625//24981863
chrX:66946770-66946771(+) m6A 3'UTR       24284625//25456834//24981863
chrX:66946781-66946782(+) m6A 3'UTR       24284625//25456834//24981863
chrX:66946871-66946872(+) m6A 3'UTR       24284625//24209618//25456834//24981863
chrX:66946890-66946891(+) m6A 3'UTR       24284625//24209618//25456834//24981863
chrX:66947094-66947095(+) m6A 3'UTR       24981863
chrX:66947971-66947972(+) m6A 3'UTR       24981863
chrX:66947983-66947984(+) m6A 3'UTR       24981863
chrX:66948681-66948682(+) m6A 3'UTR       24284625//25456834//24981863
chrX:66948711-66948712(+) m6A 3'UTR       24284625//25456834//24981863//26404942
chrX:66948736-66948737(+) m6A 3'UTR       24284625//25456834//24981863//26404942
chrX:66948746-66948747(+) m6A 3'UTR       24284625//25456834//24981863//26404942
chrX:66948778-66948779(+) m6A 3'UTR       24284625//25456834//24981863//26404942
chrX:66948829-66948830(+) m6A 3'UTR       24284625//25456834//24981863//26404942
chrX:66948852-66948853(+) m6A 3'UTR       24284625//25456834//24981863
chrX:66948907-66948908(+) m6A 3'UTR       24284625//25456834//24981863
chrX:66949893-66949894(+) m6A 3'UTR       24981863
chrX:66949916-66949917(+) m6A 3'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-190a-5p
Exosome Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Plasma     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901
Microvesicle Colon cancer cell line (LIM1863)|Mesenchymal stem cells|Urine     -
AR
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Plasma     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-190a-5p
Interactor2: AR

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence miRDB
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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