Basic Information:
VIRBase ID: HHID00000587
Virus: Infectious bursal disease virus (IBDV)
Host: Gallus gallus
Confidence Score: 0.8589
Interaction Type: Host-Host interaction
Predicted Binding:
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Interactor Information:
Interactor1
Interactor2
Symbol
gga-miR-454-3p
IFNW1
miRBase Accession/Entrez ID
MIMAT0007292
554219
Organism
Gallus gallus
Gallus gallus
Category
miRNA
mRNA
Alias
-
IFN-beta//IFN_B//IFNB
Interaction Network (The top 100 interactions) :
Interactor1: gga-miR-454-3p
Interactor2: IFNW1
Evidence Support:
Strong-Evidence
qRT-PCR
Weak-Evidence
Deep sequencing
Support Database
ViRBase
References:
PMID
29777734
Target region
None
Source
ViRBase
Interactor1 expression
Upregulation
Tissue or cell line
DF-1 cells
Interactor2 expression
Upregulation
Description
We found that overexpression of miR-454 enhanced the expressions of IFN-beta, IRF3 and NF-kappaB-p65 except IFN-alpha in cell response to IBDV infection or poly (I:C) stimulation (Fig. 3A-D).