Detail Information

Basic Information:


  VIRBase ID:  

HHID00000587

  Virus:  

Infectious bursal disease virus (IBDV)

  Host:  

Gallus gallus

  Confidence Score:  

0.8589

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      gga-miR-454-3p:           IFNW1:      

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Interactor Information:


Interactor1 Interactor2
Symbol gga-miR-454-3p IFNW1
miRBase
Accession/Entrez ID
MIMAT0007292 554219
Organism Gallus gallus Gallus gallus
Category miRNA mRNA
Alias - IFN-beta//IFN_B//IFNB

Interaction Network (The top 100 interactions):


Interactor1: gga-miR-454-3p
Interactor2: IFNW1

Evidence Support:


Strong-Evidence qRT-PCR
Weak-Evidence Deep sequencing
Support Database ViRBase

References:


PMID 29777734 Target region None
Source ViRBase Interactor1 expression Upregulation
Tissue or cell line DF-1 cells Interactor2 expression Upregulation
Description We found that overexpression of miR-454 enhanced the expressions of IFN-beta, IRF3 and NF-kappaB-p65 except IFN-alpha in cell response to IBDV infection or poly (I:C) stimulation (Fig. 3A-D).

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