Basic Information:

  VIRBase ID:  

HHID00000584

  Virus:  

Infectious bursal disease virus (IBDV)

  Host:  

Gallus gallus

  Confidence Score:  

0.8589

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      gga-miR-454-3p:  MIMAT0007292          NFKB1:  NM_205134     

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Interactor Information:

	Interactor1	Interactor2
Symbol	gga-miR-454-3p	NFKB1
miRBase Accession/Entrez ID	MIMAT0007292	396033
Organism	Gallus gallus	Gallus gallus
Category	miRNA	mRNA
Alias	-	NF-KB1

Interaction Network (The top 100 interactions):

Interactor1: gga-miR-454-3p
Interactor2: NFKB1

Evidence Support:

Strong-Evidence	qRT-PCR
Weak-Evidence	Deep sequencing
Support Database	ViRBase

References:

PMID	29777734	Target region	None
Source	ViRBase	Interactor1 expression	Upregulation
Tissue or cell line	DF-1 cells	Interactor2 expression	Upregulation
Description	We found that overexpression of miR-454 enhanced the expressions of IFN-beta, IRF3 and NF-kappaB-p65 except IFN-alpha in cell response to IBDV infection or poly (I:C) stimulation (Fig. 3A-D).