Basic Information:

  VIRBase ID:  

HHID00000258

  Virus:  

Porcine reproductive and respiratory syndrome virus (PRRSV)

  Host:  

Sus scrofa

  Confidence Score:  

0.9612

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      ssc-miR-30c-3p:  MIMAT0022922          IFNAR2:  NM_001204775     

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Interactor Information:

	Interactor1	Interactor2
Symbol	ssc-miR-30c-3p	IFNAR2
miRBase Accession/Entrez ID	MIMAT0022922	100533555
Organism	Sus scrofa	Sus scrofa
Category	miRNA	mRNA
Alias	-	-

Interaction Network (The top 100 interactions):

Interactor1: ssc-miR-30c-3p
Interactor2: IFNAR2

Evidence Support:

Strong-Evidence	Luciferase reporter assay//qRT-PCR//Western blot
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	30382935	Target region	3'UTR
Source	ViRBase	Interactor1 expression	Upregulation
Tissue or cell line	Porcine alveolar macrophages	Interactor2 expression	Downregulation
Description	As shown in Fig. 2a, the level of IFNAR2 mRNA was converted when the miR-30c inhibitor was transfected.