KEGG pathways enriched for interacted genes |
pathway name | pathway description | target genes enrich in pathway | p-value |
|
hsa05012
|
Parkinson's disease |
UQCR10,ND3,COX2,NDUFA2,UBB,ATP5E, |
1.02E-1 |
hsa05016
|
Huntington's disease |
AP2B1,POLR2E,UQCR10,CLTC,COX2,NDUFA2,ATP5E, |
1.04E-1 |
hsa03010
|
Ribosome |
RPL36A,RPS26,RPL37A,RPS15,RPS6, |
1.23E-1 |
hsa00190
|
Oxidative phosphorylation |
UQCR10,ND3,COX2,NDUFA2,ATP5E, |
4.55E-1 |
hsa04260
|
Cardiac muscle contraction |
MYL2,UQCR10,COX2,ATP1A1, |
4.70E-1 |
|
hsa03022
|
Basal transcription factors |
GTF2H1,GTF2H2C,GTF2I, |
5.09E-1 |
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Gene ontology terms enriched for interacted genes |
GO terms | GO terms description | target genes enrich in GO term | p-value |
|
GO:0006412
|
translation |
RPL36A,MRPS33,RARS,EIF2C2,EIF5A,RPS26,UBB,RPL37A,RPS15,RPS6,RPL7L1, |
1.17E-4 |
GO:0006119
|
oxidative phosphorylation |
UQCR10,ND3,DLD,COX2,NDUFA2,ATP5E, |
6.53E-4 |
GO:0042773
|
ATP synthesis coupled electron transport |
UQCR10,ND3,DLD,COX2,NDUFA2, |
6.59E-4 |
GO:0042775
|
mitochondrial ATP synthesis coupled electron transport |
UQCR10,ND3,DLD,COX2,NDUFA2, |
6.59E-4 |
GO:0006414
|
translational elongation |
RPL36A,RPS26,UBB,RPL37A,RPS15,RPS6, |
7.49E-4 |
|
GO:0022904
|
respiratory electron transport chain |
UQCR10,ND3,DLD,COX2,NDUFA2, |
1.09E-2 |
GO:0006367
|
transcription initiation from RNA polymerase II promoter |
GTF2H1,POLR2E,MED12,GTF2H2C,GTF2I, |
1.37E-2 |
GO:0006352
|
transcription initiation |
GTF2H1,POLR2E,MED12,GTF2H2C,GTF2I, |
2.85E-2 |
GO:0006417
|
regulation of translation |
EIF2C2,PUM1,EIF5A,EIF2C1,TNRC6B,MTOR, |
2.89E-2 |
GO:0043086
|
negative regulation of catalytic activity |
DHCR24,ADCY9,RB1,UBB,DNAJA3,TRIB1,PSMA2,GNAL, |
3.53E-2 |
GO:0042127
|
regulation of cell proliferation |
FOSL2,CAPNS1,RB1,TRIB1,DNAJA3,FGFR3,SERPINE1,MTOR,DHCR24,IGF1R,CUL2,CUL3,EIF5A,SKI, |
3.63E-2 |
GO:0010608
|
posttranscriptional regulation of gene expression |
EIF2C2,PUM1,EIF5A,EIF2C1,DNAJA3,TNRC6B,MTOR, |
3.87E-2 |
GO:0006351
|
transcription, DNA-dependent |
GTF2H1,POLR2E,NFE2L1,MED12,NPM3,APEX1,GTF2H2C,GTF2I, |
4.71E-2 |
GO:0045333
|
cellular respiration |
UQCR10,ND3,DLD,COX2,NDUFA2, |
4.98E-2 |
GO:0032774
|
RNA biosynthetic process |
GTF2H1,POLR2E,NFE2L1,MED12,NPM3,APEX1,GTF2H2C,GTF2I, |
5.07E-2 |
GO:0006366
|
transcription from RNA polymerase II promoter |
GTF2H1,POLR2E,NFE2L1,MED12,APEX1,GTF2H2C,GTF2I, |
6.38E-2 |
GO:0065003
|
macromolecular complex assembly |
SNRNP200,IGF1R,TOMM22,GTF2H1,POLR2E,MED12,TUBG1,GTF2H2C,SKI,GTF2I,RPS15,SRSF10, |
7.36E-2 |
GO:0022900
|
electron transport chain |
UQCR10,ND3,DLD,COX2,NDUFA2, |
8.77E-2 |
GO:0044092
|
negative regulation of molecular function |
DHCR24,ADCY9,RB1,UBB,DNAJA3,TRIB1,PSMA2,GNAL, |
9.59E-2 |
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