ncRNADetailInformation

Detail Information
Functional analysis

miRNA name

pre-miRNA

family

pre-miRNA Sequence

mature-miRNA

mature sequence

pre-miRNA description

miR-92a

MI0000094	MIPF0000013	UCAUCCCUGGGUGGGGAUUUGUUGCAUUACUUGUGUUCUAUAUAAAGUAUUGCACUUGUCCCGGCCUGUGGAAGA	MIMAT0000092 hsa-miR-92a-3p	UAUUGCACUUGUCCCGGCCUGU	Human miR-92a (previously named miR-92 here) has two predicted hairpinprecursor sequences: mir-92a-1 (MIR:MI0000093) on chromosome 13 (namedmir-92-13 in ) and mir-92a-2 (MIR:MI0000094) on chromosome X (namedmir-92-X in ). miR-92a has also been cloned from mouse embryonic stemcells and is predicted to be expressed from two closely relatedprecursor hairpins (MIR:MI0000719 and MIR:MI0000580). The mature sequenceshown here represents the most commonly cloned form from large-scalecloning studies .
MI0000093	MIPF0000013	CUUUCUACACAGGUUGGGAUCGGUUGCAAUGCUGUGUUUCUGUAUGGUAUUGCACUUGUCCCGGCCUGUUGAGUUUGG	MIMAT0004507 hsa-miR-92a-1-5p	AGGUUGGGAUCGGUUGCAAUGCU	Human miR-92a (previously named miR-92 here) has two predicted hairpinprecursor sequences: mir-92a-1 (MIR:MI0000093) on chromosome 13 (namedmir-92-13 in ) and mir-92a-2 (MIR:MI0000094) on chromosome X (namedmir-92-X in ). miR-92a has also been cloned from mouse embryonic stemcells and is predicted to be expressed from two closely relatedprecursor hairpins (MIR:MI0000719 and MIR:MI0000580). The mature sequenceshown here represents the most commonly cloned form from large-scalecloning studies .
MI0000094	MIPF0000013	UCAUCCCUGGGUGGGGAUUUGUUGCAUUACUUGUGUUCUAUAUAAAGUAUUGCACUUGUCCCGGCCUGUGGAAGA	MIMAT0004508 hsa-miR-92a-2-5p	GGGUGGGGAUUUGUUGCAUUAC	Human miR-92a (previously named miR-92 here) has two predicted hairpinprecursor sequences: mir-92a-1 (MIR:MI0000093) on chromosome 13 (namedmir-92-13 in ) and mir-92a-2 (MIR:MI0000094) on chromosome X (namedmir-92-X in ). miR-92a has also been cloned from mouse embryonic stemcells and is predicted to be expressed from two closely relatedprecursor hairpins (MIR:MI0000719 and MIR:MI0000580). The mature sequenceshown here represents the most commonly cloned form from large-scalecloning studies .
MI0000094	MIPF0000013	UCAUCCCUGGGUGGGGAUUUGUUGCAUUACUUGUGUUCUAUAUAAAGUAUUGCACUUGUCCCGGCCUGUGGAAGA	MIMAT0000092 hsa-miR-92a-3p	UAUUGCACUUGUCCCGGCCUGU	Human miR-92a (previously named miR-92 here) has two predicted hairpinprecursor sequences: mir-92a-1 (MIR:MI0000093) on chromosome 13 (namedmir-92-13 in ) and mir-92a-2 (MIR:MI0000094) on chromosome X (namedmir-92-X in ). miR-92a has also been cloned from mouse embryonic stemcells and is predicted to be expressed from two closely relatedprecursor hairpins (MIR:MI0000719 and MIR:MI0000580). The mature sequenceshown here represents the most commonly cloned form from large-scalecloning studies .
MI0000093	MIPF0000013	CUUUCUACACAGGUUGGGAUCGGUUGCAAUGCUGUGUUUCUGUAUGGUAUUGCACUUGUCCCGGCCUGUUGAGUUUGG	MIMAT0004507 hsa-miR-92a-1-5p	AGGUUGGGAUCGGUUGCAAUGCU	Human miR-92a (previously named miR-92 here) has two predicted hairpinprecursor sequences: mir-92a-1 (MIR:MI0000093) on chromosome 13 (namedmir-92-13 in ) and mir-92a-2 (MIR:MI0000094) on chromosome X (namedmir-92-X in ). miR-92a has also been cloned from mouse embryonic stemcells and is predicted to be expressed from two closely relatedprecursor hairpins (MIR:MI0000719 and MIR:MI0000580). The mature sequenceshown here represents the most commonly cloned form from large-scalecloning studies .
MI0000094	MIPF0000013	UCAUCCCUGGGUGGGGAUUUGUUGCAUUACUUGUGUUCUAUAUAAAGUAUUGCACUUGUCCCGGCCUGUGGAAGA	MIMAT0004508 hsa-miR-92a-2-5p	GGGUGGGGAUUUGUUGCAUUAC	Human miR-92a (previously named miR-92 here) has two predicted hairpinprecursor sequences: mir-92a-1 (MIR:MI0000093) on chromosome 13 (namedmir-92-13 in ) and mir-92a-2 (MIR:MI0000094) on chromosome X (namedmir-92-X in ). miR-92a has also been cloned from mouse embryonic stemcells and is predicted to be expressed from two closely relatedprecursor hairpins (MIR:MI0000719 and MIR:MI0000580). The mature sequenceshown here represents the most commonly cloned form from large-scalecloning studies .
MI0000094	MIPF0000013	UCAUCCCUGGGUGGGGAUUUGUUGCAUUACUUGUGUUCUAUAUAAAGUAUUGCACUUGUCCCGGCCUGUGGAAGA	MIMAT0000092 hsa-miR-92a-3p	UAUUGCACUUGUCCCGGCCUGU	Human miR-92a (previously named miR-92 here) has two predicted hairpinprecursor sequences: mir-92a-1 (MIR:MI0000093) on chromosome 13 (namedmir-92-13 in ) and mir-92a-2 (MIR:MI0000094) on chromosome X (namedmir-92-X in ). miR-92a has also been cloned from mouse embryonic stemcells and is predicted to be expressed from two closely relatedprecursor hairpins (MIR:MI0000719 and MIR:MI0000580). The mature sequenceshown here represents the most commonly cloned form from large-scalecloning studies .
MI0000094	MIPF0000013	UCAUCCCUGGGUGGGGAUUUGUUGCAUUACUUGUGUUCUAUAUAAAGUAUUGCACUUGUCCCGGCCUGUGGAAGA	MIMAT0000092 hsa-miR-92a-3p	UAUUGCACUUGUCCCGGCCUGU	Human miR-92a (previously named miR-92 here) has two predicted hairpinprecursor sequences: mir-92a-1 (MIR:MI0000093) on chromosome 13 (namedmir-92-13 in ) and mir-92a-2 (MIR:MI0000094) on chromosome X (namedmir-92-X in ). miR-92a has also been cloned from mouse embryonic stemcells and is predicted to be expressed from two closely relatedprecursor hairpins (MIR:MI0000719 and MIR:MI0000580). The mature sequenceshown here represents the most commonly cloned form from large-scalecloning studies .

link to database

TargetScanS 6.2 | MicroCosm | microRNA.org | miRNAMap 2.0

Interacted genes from RAID,miRTarBase

FUK,DCAF16,CNOT1,AARS2,IFT172,NPM1,DHX8,SLC6A8,SNX9,SYNJ1,CMTM6,WDR6,CCNE1,TOM1L1,SKI
more » FUK,DCAF16,CNOT1,AARS2,IFT172,NPM1,DHX8,SLC6A8,SNX9,SYNJ1,CMTM6,WDR6,CCNE1,TOM1L1,SKI,WEE1,NEK6,SREBF2,RAD23B,PDS5B,DNM2,TMED9,PCBP2,ACACA,BAK1,CCDC57,GABPA,TGFA,HSPA8,HNRNPF,GABARAPL2,ELAC2,SHISA5,DIDO1,SELRC1,CD2BP2,USP9X,SLC7A1,PLCG1,ZFYVE20,C17orf51,AXIN1,TRAF3IP1,OGT,HDAC1,GSK3B,RIOK1,HIST2H2AA3,OAZ1,SLC25A33,ANXA11,MEF2C,CARS,TFAM,PSMB1,HMGB1,MRPL9,CLSPN,KIAA0100,KAT2B,NTHL1,FAM189B,KHDRBS1,CRTC3,POP4,SLC4A2,HIST1H1E,MYO1C,DDRGK1,RSPRY1,SELENBP1,CHN1,CD59,DDX56,SMC3,KIAA1671,UFSP2,EFTUD2,MAPK9,C22orf28,NEK2,PRR12,CKB,MYLIP,KLHL11,UCHL1,RPS23,HMGCR,GTF3C2,IER3IP1,CDC25A,STAG1,KIF20A,TMF1,C14orf135,TEX10,PSMC3,PPP4C,GTPBP4,RPS10,MYBL2,FASN,USP10,ARID4B,SRSF5,CBFA2T2,MPG,PSMA4,PFKM,DCP2,NCDN,DYNC1H1,TSR1,SCARB2,DYRK1A,CCDC86,PDLIM1,RAD51,PLA2G4F,TRAP1,G3BP2,CDK9,SLAIN1,ARPC2,CBX5,STK25,EPHA7,MRPL3,MLF2,EP300,TPRN,ABCA3,TUBB4B,STARD7,FKBP8,MYH9,C12orf57,BID,CSPG5,MAFG,E4F1,CCND1,EPB41L3,ZNF420,CDH1,TBCEL,XYLT2,NCAPH,ZCCHC2,NSFL1C,TAX1BP3,MYL6,MAVS,RRP9,BAG6,DHX30,KIAA1549,CPSF6,MYH2,SHOC2,MLL2,GAPDH,POLR2L,HSP90AB1,RNPS1,NDUFA7,DDX17,NRXN3,HEATR6,XPO1,ACAT2,TTC32,CEP85,SIPA1L1,SMC1A,RPLP1,RCN3,MAU2,PDXK,HOGA1,BRCC3,LRRC27,C11orf57,PITRM1,METTL2B,ANKS1A,TUBB,MCM3,THUMPD1,USP13,TAOK2,HSP90B1,NKX3-1,QTRT1,CD276,IPO5,UBAC2,SF3A3,RAB36,CBS,JMJD6,WDR37,ATP5B,C4orf43,PKN1,GSTP1,PSMF1,MBNL1,PDIA4,GOLM1,RPA2,CXCL16,PSMD2,ERH,RCC2,HMGCS1,IRAK1,PHF13,IQSEC1,GEMIN6,KANSL2,UBB,MYO6,ME2,FBXL19,HNRNPM,PSMB6,ENOPH1,PDE4DIP,RBBP7,EIF4B,BCL9,ZC3H18,NXN,RASA3,TUBA1C,ATP11A,DDX39A,MTMR14,SF3B3,ALKBH4,RARS,LDLRAP1,POLE,CCDC6,EIF2S3,HERC1,PITX1,ZNF551,DTWD2,MSL3,ZNF276,DEDD2,CYBRD1,FAM160B2,FAF1,BTRC,TPT1,CDKN3,CCNI,C9orf64,IPO7,BTBD7,CC2D2A,WDR83OS,DENND5A,EPHA4,SURF6,ASS1,NLE1,HNRPLL,SCAF8,NUDCD3,ABL2,RAB8A,NUP210,SHC3,P4HB,DCAF12,PFN1,ETV6,TXLNA,NOC2L,UBAP2L,ETFA,WIPF2,HIST1H2AB,ENO1,POTEG,MRPL32,CCAR1,CDC37,PLK1,PCGF5,CYP7A1,EXOSC6,R3HDM4,SLC3A2,RBX1,MBLAC2,HADHA,HELQ,ATG16L1,CBX6,NFE2L1,EZR,FLNA,MCCD1,NAPRT1,TTC5,CDK1,PLEKHB1,RHEB,OPTN,BFAR,SYNPR,ZNF622,TET2,INSIG1,TONSL,TECPR2,DNAJC21,ACTB,KPNA2,ALMS1,C10orf46,TMUB1,HSD17B10,SMAD7,FNDC3B,CHCHD2,CSTF2T,ASAH1,CHEK1,COX4I1,DHRS3,ARID1B,SSX2IP,MYO5C,RNF40,DAZAP1,MLX,IGF1R,DDX6,IRGQ,TUT1,PTS,LRP6,MAML1,OCIAD2,PIGS,KPNA6,MKRN2,SIN3B,ILF2,NTPCR,ABHD2,USP31,LAMC1,CISD1,TESK1,TLE3,CHST9,BCS1L,PRR14L,RNH1,MAPK1IP1L,EIF2AK1,PKDCC,UBE4B,SUPT5H,ESR2,EIF4G2,NSMAF,ZNF174,RXRB,ATXN7,FAM135A,SLC2A6,ZMYND8,RUVBL2,ATP5A1,PTP4A2,ARCN1,NADK,ORC6,KCTD7,NDUFA5,SUCLG1,COL4A2,GHITM,DYNLL1,C10orf114,PPP2R2A,KCTD5,ACTR1A,RPAIN,PFDN6,RPL11,METTL16,CSDE1,CAD,MDM2,UBR1,RNF2,ZNF776,AHCYL1,SPTLC1,F8A3,GANAB,CTC1,DNAJB12,KDM3B,SEC24A,HCFC1,RPL29,TCEB2,C1orf96,CDC20,SERTAD3,FRAT2,YWHAQ,KCNC1,NUP155,NHSL1,CA5B,VANGL2,LXN,GLOD4,SUGP1,MLLT4,MRPL2,RANBP2,RAVER1,APOLD1,ATP1A1,LMBR1L,DHX16,APOBEC3C,PSMD3,PTK7,SACM1L,EFNA5,EIF3B,RPL22,FAU,SREK1IP1,SMAD4,COPG,ZNF507,HS3ST3A1,RPS8,RPL3,IK,MINK1,GOLIM4,BMPR2,SCD5,PDAP1,CTSB,CDC42SE1,BSG,VARS,ARF1,JAG2,GGA2,SCYL2,POGZ,TUBGCP2,PPP1CC,H1FX,GATAD2A,EIF6,CEP97,CUL5,RPS28,TMEM161A,GCHFR,IL17RA,ESD,KPNB1,TUBB3,PPAN,HES1,MTHFSD,SCML2,FAM203A,BTAF1,TNFRSF10B,TUFM,STMN3,ITGA5,RANGAP1,HIPK1,PCMTD1,RHOT2,POLR3A,DDX23,RPS3A,DDAH1,PPARD,CDKN2AIPNL,LMNB2,HIST1H2AE,RPS15A,BBX,HIPK3,RNF123,PDCD6IP,TRAPPC11,FAM129B,KLC2,LDLR,GATA3,SIN3A,CCNB1,PRKCA,SLC20A1,MYEF2,FHOD1,PARK7,LPIN1,SARS2,KIFC1,TYMP,PA2G4,AGPAT5,CD2AP,PPP1R3G,PSMA7,AP2B1,SUCLG2,TRAPPC2,CCT7,TFG,FKBP4,TGFBRAP1,U2AF2,ACADS,NHP2L1,EARS2,ERGIC1,SETD1B,KLHL3,SART3,GNG7,CUX1,MKI67,EIF2C4,AURKB,CBFB,SAP30BP,ELF4,POR,PLCXD2,CLNS1A,NDST1,DOT1L,KDSR,MAP3K4,KIF18B,BRD2,C1orf114,RPS14,LRIG1,MAP4,DHTKD1,TMEM66,BTF3,BRF1,TANC2,GATA5,BLMH,NMD3,B4GALT2,DHRS7B,TBC1D9B,LIMD1,PPIB,RECQL,KLF2,HSPH1,MAPRE1,CELSR1,TMEM55B,HLA-E,HIP1R,ANKH,DHCR24,RRM1,SNF8,FAM136A,NOTCH2,TTC7B,TGFBR2,NPLOC4,RPL13A,THBS1,PTPLAD2,MCOLN2,FKBP1A,RNF121,DOPEY2,EMD,EIF3I,RPL39,TP63,PRELID1,FAM116A,CHCHD5,PSMG3,BCL2L11,TNRC18,UBE2R2,TERF2,HIST1H2AM,ZNF84,WDR1,PYGL,RPS24,WHSC1,DCTD,ARID1A,NPC2,PKM2,KANSL3,EHBP1,NFIB,TWISTNB,NDUFB10,PBX2,RASA1,STX3,PLEKHH3,HSPBP1,SPEN,WDR19,ACLY,VCPIP1,PURB,EIF2B2,TCOF1,PPP6R2,ZC3HAV1,SCLY,CDV3,SLC2A4,AMOTL1,YIPF5,RASAL2,IQGAP1,URB2,GPR89A,PEBP1,HIST1H2AH,GBP4,SLC25A44,NAB1,RORA,FLNB,IGSF1,RABGAP1,HIST1H4C,KLHL36,COL4A1,TALDO1,PRRC2B,SAP30,ANKLE2,ATP13A1,PTBP1,NARF,MED16,ITPR3,XPOT,TRIM28,EIF3K,OSBPL2,ZNF282,EGLN2,SAFB,DNAJA3,TSPAN18,ZNF703,FTSJ1,DENND4B,MDN1,TNPO1,MYO1D,PRPF8,MECP2,OTUD6A,FAM168B,TKT,ARL2,RCAN1,IKBKAP,GDPD5,MCM7,EEF1A1,EFNB1,RAB11A,ABHD15,TMCC3,EBP,C20orf20,RNF128,PRC1,TTC37,UPF2,CSDA,TMEM160,FLYWCH1,ZWINT,PXN,KAT2A,PTPN13,WDR18,CAPRIN1,RPL8,MACF1,SMAP2,CRTC2,NUCB1,HIST1H2AC,ORC5,AMMECR1,LY6G5B,ERAP1,ATM,KHSRP,DDX5,DUSP11,RPL24,CERS1,SLC25A38,CPEB2,MTFP1,FAM83G,TRMT61A,IPO4,CXorf56,LARP1,STK4,NAA25,LTBP1,SEC14L1,GPX3,TMEM184B,HDGF,EIF3C,HMGXB3,UGDH,ALKBH5,SLC25A3,PPIL1,KIF2C,ADAMTS1,ATP5J,AHCYL2,AIDA,RIC8A,SRPRB,ZFYVE16,TCHP,GOT2,DLX6,FYCO1,NFKB1,GOLGA3,NDUFV3,ZBTB22,CTTN,RBM10,COX18,CARM1,ELOF1,C5orf44,LARS,RPS25,TFPI,MINA,LSM7,OGFR,FAM69B,PTGFRN,CHAF1A,NBR1,DMXL1,ERGIC2,CLTC,IARS2,ATXN2L,GAK,COPS6,TRAF4,PABPN1,POLRMT,FBXO45,PANK2,RPS15,AK2,TLN1,CYP4V2,RPL15,SCD,LRRC37A2,SLC12A4,QSOX2,SRRT,NUP205,KPTN,DTL,EEF2,CES2,FAM20C,MFSD1,ISM2,FNIP1,MKNK2,ZNF629,KDELR1,ALDH9A1,POLR2I,CTLA4,ZNF503,ELOVL6,MYO19,CRBN,TUSC2,PDIK1L,RPL7A,PHACTR4,FKBPL,CBR1,MYBBP1A,RCC1,KLHL15,BAHCC1,TUBB2B,AAGAB,PITPNA,C6orf108,PFDN2,TBL1X,SNRNP70,GBAS,SETDB1,CREB3L2,C9orf7,CORO7,GNPNAT1,NT5DC3,COL18A1,RPS5,PHF12,SNRPE,TLR10,TPD52L3,WNT5A,HNRNPA2B1,ZNF687,KHNYN,CAMTA2,UNC13B,PPP2R1A,CD3EAP,POLI,CBX2,PPP6C,STEAP3,CLIC1,CHTOP,FAM3A,AUP1,CYB5R3,KIAA1468,GTF3C1,SRPR,TPM3,RBM27,VBP1,METTL2A,EDC4,ATXN1,NCL,GLO1,RPL18A,TTLL7,EIF3G,MAP3K6,C1orf174,ADRM1,ZFHX4,PON2,KPNA3,KIF1A,SURF4,C22orf29,HIST1H3D,WASL,ATAD3A,ARHGDIA,SRF,HEATR1,SCARB1,ARPP19,CAMKV,TRIP12,TTL,SHPRH,EIF2C1,CIT,AP3D1,CHCHD10,WDR26,POMGNT1,MRPS11,IRF2BPL,HBB,CKMT1B,CTNNBL1,EPHB2,COX1,BCL9L,RRBP1,RPL27,YIF1B,KANK2,PSMD11,SHMT2,CLDND1,RABGGTB,ZNF785,STAT3,KDM6B,FGF2,SV2A,RFFL,UBE2H,FAM58A,MARS,PWP2,FAM73B,MEN1,NDRG3,CDK11A,DIAPH1,MAP1B,HSPA1B,MFN2,HAUS1,ARHGEF25,SERINC1,NACC2,OSBPL8,ZFYVE26,HOXA5,C5orf42,ARRB1,GARNL3

KEGG pathways enriched for interacted genes

pathway name

pathway description

target genes enrich in pathway

p-value

hsa03010	Ribosome	RPL22,RPL39,RPL3,RPL11,RPL8,RPL13A,RPL18A,RPL7A,RPS10,RPL27,RPS3A,RPL24,RPS25,RPL29,RPS15,RPLP1,RPS28,RPS24,RPS23,RPS8,RPS15A,FAU,RPL15,RPS5,	4.78E-9
hsa04110	Cell cycle	ORC6,CCND1,SMC1A,YWHAQ,MCM3,MCM7,EP300,CHEK1,GSK3B,MDM2,WEE1,CDK1,ORC5,CDC25A,SMC3,STAG1,PLK1,CDC20,ATM,HDAC1,RBX1,SMAD4,CCNB1,CCNE1,	5.43E-6
hsa05130	Pathogenic Escherichia coli infection	CTTN,YWHAQ,WASL,PRKCA,TUBB2B,TUBB4B,EZR,TUBB3,TUBB,TUBA1C,ACTB,NCL,ARPC2,CDH1,	6.41E-5
hsa05200	Pathways in cancer	TFG,STAT3,CCDC6,PRKCA,EP300,GSK3B,WNT5A,NKX3-1,IGF1R,GSTP1,STK4,FGF2,RAD51,RBX1,TGFBR2,TCEB2,HSP90B1,CCND1,MAPK9,COL4A1,TRAF4,BID,TGFA,COL4A2,RXRB,MDM2,HSP90AB1,PPARD,PLCG1,AXIN1,LAMC1,HDAC1,SMAD4,NFKB1,EGLN2,CCNE1,TPM3,CDH1,	8.05E-4
hsa03040	Spliceosome	HSPA1B,HNRNPM,EFTUD2,SNRPE,SRSF5,SNRNP70,HSPA8,SF3B3,LSM7,PPIL1,DHX16,U2AF2,SF3A3,DDX5,PRPF8,CTNNBL1,DHX8,DDX23,NHP2L1,	1.46E-2

hsa04115	p53 signaling pathway	CCND1,STEAP3,BID,TNFRSF10B,ATM,CHEK1,SHISA5,MDM2,CCNB1,CCNE1,THBS1,CDK1,	4.62E-2
hsa00970	Aminoacyl-tRNA biosynthesis	AARS2,RARS,SARS2,IARS2,LARS,VARS,CARS,EARS2,MARS,	4.74E-2
hsa03050	Proteasome	PSMD11,PSMF1,PSMA7,PSMB1,PSMD2,PSMD3,PSMC3,PSMA4,PSMB6,	1.10E-1
hsa05215	Prostate cancer	CCND1,CREB3L2,TGFA,EP300,GSK3B,MDM2,HSP90AB1,NKX3-1,IGF1R,GSTP1,NFKB1,HSP90B1,CCNE1,	1.36E-1
hsa00450	Selenoamino acid metabolism	AHCYL1,METTL2B,CBS,AHCYL2,MARS,SCLY,	2.57E-1
hsa04114	Oocyte meiosis	SMC1A,YWHAQ,ITPR3,BTRC,CDK1,IGF1R,SMC3,PPP2R1A,PPP1CC,CDC20,PLK1,RBX1,CCNB1,CCNE1,	2.89E-1
hsa04520	Adherens junction	IGF1R,MLLT4,SSX2IP,WASL,IQGAP1,EP300,SMAD4,TGFBR2,ACTB,LY6G5B,CDH1,	2.95E-1
hsa04330	Notch signaling pathway	JAG2,NOTCH2,KAT2B,EP300,HES1,HDAC1,MAML1,KAT2A,	3.34E-1
hsa05216	Thyroid cancer	CCND1,TFG,CCDC6,RXRB,TPM3,CDH1,	3.95E-1
hsa04310	Wnt signaling pathway	CCND1,MAPK9,LRP6,PRKCA,EP300,GSK3B,BTRC,VANGL2,PPARD,WNT5A,PPP2R1A,AXIN1,TBL1X,RBX1,SMAD4,FRAT2,LY6G5B,	4.07E-1
hsa00640	Propanoate metabolism	ALDH9A1,SUCLG1,HADHA,SUCLG2,ACACA,ACAT2,	5.70E-1
hsa00310	Lysine degradation	SETDB1,ALDH9A1,HADHA,SETD1B,WHSC1,DOT1L,ACAT2,	6.80E-1
hsa03018	RNA degradation	CNOT1,DDX6,DCP2,ENO1,TTC37,EDC4,LSM7,EXOSC6,	8.05E-1
hsa05016	Huntington's disease	CREB3L2,ATP5B,SIN3A,NDUFB10,NDUFA5,EP300,POLR2I,NDUFA7,COX4I1,NDUFV3,ATP5A1,ATP5J,AP2B1,CLTC,HDAC1,TFAM,COX1,POLR2L,	8.62E-1

Gene ontology terms enriched for interacted genes

GO terms

GO terms description

target genes enrich in GO term

p-value

GO:0006414	translational elongation	RPL22,RPL3,RPL18A,EEF2,RPS10,RPS3A,EEF1A1,RPS14,RPS15,RPS15A,FAU,RPL15,RPL39,RPL11,RPL8,RPL13A,RPL7A,TUFM,RPL27,VARS,RPL24,RPS25,RPL29,UBB,RPLP1,RPS28,RPS24,RPS23,RPS8,RPS5,	1.18E-13
GO:0006412	translation	RPL3,RARS,EEF2,MRPL3,RPS10,RPS14,RPS15,RPS15A,EIF3I,FAU,EIF3K,EIF4B,MRPL32,TUFM,IARS2,RPL27,LARS,VARS,RPL24,RPL29,EIF6,UBB,CARS,EIF4G2,MRPL9,RPS5,RPL22,RPL18A,MRPL2,RPS3A,EEF1A1,RRBP1,SARS2,BRF1,MRPS11,EIF2B2,RPL15,AARS2,RPL39,RPL11,RPL8,RPL13A,RPL7A,EIF2S3,EIF3C,EIF3B,RPS25,EIF3G,RPLP1,RPS28,RPS24,RPS8,RPS23,EARS2,MARS,	1.01E-12
GO:0000278	mitotic cell cycle	PPP6C,RCC1,PSMA4,CDK1,PSMF1,TUBB3,KHDRBS1,PSMD2,PSMD3,CUL5,MDM2,PSMC3,RPL24,UBB,PSMB6,PSMA7,PSMB1,AURKB,KIF2C,NEK2,CD2AP,PRC1,SMC1A,PSMD11,RCC2,ZWINT,NCAPH,TUBB2B,BTRC,MAPRE1,DNM2,CDKN3,RNF2,VCPIP1,SMC3,STAG1,PLK1,USP9X,CCND1,KPNA2,POLE,E4F1,KIFC1,CHEK1,WEE1,DYNC1H1,CIT,CDC25A,CDC20,TUBB,MAU2,PDS5B,CCNB1,HAUS1,NEK6,CCNE1,CDK11A,	8.69E-12
GO:0007049	cell cycle	GAK,CLSPN,CCAR1,SUPT5H,NOTCH2,PPP6C,RCC1,MFN2,PSMA4,CDK1,PSMF1,TUBB3,RAD51,KHDRBS1,HCFC1,JAG2,PSMD2,PSMD3,CUL5,PSMC3,WDR6,MDM2,RPL24,UBB,PSMB6,PA2G4,TET2,EIF4G2,PSMA7,DHCR24,AURKB,PSMB1,KIF2C,PPP1CC,ATM,NEK2,MEN1,CD2AP,ARL2,PRC1,TUSC2,PSMD11,RCC2,SMC1A,RABGAP1,ZWINT,EP300,TUBB2B,NCAPH,GSK3B,BTRC,MAPRE1,DNM2,CDKN3,PDCD6IP,RNF2,VCPIP1,SMC3,STAG1,PLK1,USP9X,CCND1,MCM3,TERF2,CHAF1A,KAT2B,MCM7,NPM1,KPNA2,POLE,E4F1,KIFC1,CHEK1,WEE1,DYNC1H1,CIT,MACF1,ERH,STEAP3,CDC25A,MYH9,MKI67,CDC20,MAU2,TUBB,PDS5B,HAUS1,CCNB1,NEK6,CCNE1,THBS1,CDK11A,	9.64E-12
GO:0022402	cell cycle process	NOTCH2,PPP6C,RCC1,PSMA4,MFN2,CDK1,PSMF1,TUBB3,RAD51,KHDRBS1,PSMD2,PSMD3,CUL5,PSMC3,WDR6,MDM2,RPL24,UBB,PSMB6,PA2G4,EIF4G2,DHCR24,PSMA7,AURKB,PSMB1,KIF2C,NEK2,ATM,MEN1,CD2AP,PRC1,SMC1A,RCC2,PSMD11,ZWINT,NCAPH,TUBB2B,GSK3B,BTRC,MAPRE1,DNM2,CDKN3,VCPIP1,SMC3,STAG1,PLK1,USP9X,CCND1,KAT2B,NPM1,KPNA2,POLE,E4F1,KIFC1,CHEK1,WEE1,DYNC1H1,CIT,MACF1,CDC25A,MYH9,MKI67,CDC20,TUBB,MAU2,PDS5B,HAUS1,CCNB1,NEK6,CCNE1,CDK11A,THBS1,	1.04E-10

GO:0065003	macromolecular complex assembly	GCHFR,POLR2I,RPS14,FKBP4,RPS15,HIST1H1E,TUBB4B,IGF1R,DIAPH1,TUBB3,HIST1H2AE,HIST1H4C,TFAM,RAD51,SKI,H1FX,TCEB2,MBNL1,POLR2L,WASL,ITPR3,ATG16L1,TP63,MDM2,SF3B3,RPL24,EIF6,IPO4,NUP205,PFDN6,PEBP1,HIST1H3D,LAMC1,CD2AP,SMAD4,ARL2,ADRM1,IPO7,SNRPE,XPO1,IKBKAP,TUBB2B,NACC2,FLNA,RRM1,IPO5,TSR1,TNPO1,HSD17B10,PFKM,CDK9,SHPRH,MDN1,SF3A3,PPP2R1A,GPX3,BRF1,TUBA1C,COX18,IRAK1,PXN,TUBGCP2,CHAF1A,KPNB1,GEMIN6,NPM1,KPNA3,SRSF5,MED16,FKBP1A,HIST1H2AH,UNC13B,HIST2H2AA3,TUBB,HIST1H2AM,HIST1H2AB,HIST1H2AC,BCS1L,CLNS1A,DDX23,CDH1,	3.29E-10
GO:0043933	macromolecular complex subunit organization	GCHFR,POLR2I,RPS14,SCARB1,RPS15,FKBP4,HIST1H1E,TUBB4B,IGF1R,DIAPH1,TUBB3,HIST1H2AE,HIST1H4C,TFAM,RAD51,SKI,H1FX,TCEB2,MBNL1,POLR2L,WASL,ITPR3,ATG16L1,TP63,MDM2,SF3B3,RPL24,EIF6,IPO4,NUP205,PFDN6,PEBP1,KIF2C,HIST1H3D,LAMC1,CD2AP,SMAD4,ARL2,ADRM1,IPO7,SNRPE,IKBKAP,XPO1,TUBB2B,NACC2,FLNA,RRM1,IPO5,TSR1,TNPO1,HSD17B10,PFKM,CDK9,SHPRH,MDN1,SF3A3,PPP2R1A,GPX3,BRF1,TUBA1C,ARID1A,COX18,IRAK1,PXN,TUBGCP2,CHAF1A,KPNB1,GEMIN6,NPM1,KPNA3,SRSF5,MED16,FKBP1A,HIST1H2AH,UNC13B,HIST2H2AA3,TUBB,HIST1H2AM,HIST1H2AB,HIST1H2AC,BCS1L,CLNS1A,DDX23,CDH1,	5.76E-10
GO:0034622	cellular macromolecular complex assembly	RPS14,RPS15,FKBP4,HIST1H1E,TUBB4B,DIAPH1,TUBB3,HIST1H2AE,TFAM,HIST1H4C,H1FX,MBNL1,RPL24,EIF6,NUP205,IPO4,PFDN6,HIST1H3D,SMAD4,ARL2,ADRM1,IPO7,SNRPE,XPO1,TUBB2B,FLNA,IPO5,TNPO1,TSR1,SHPRH,SF3A3,TUBA1C,COX18,PXN,CHAF1A,KPNB1,GEMIN6,NPM1,SRSF5,FKBP1A,HIST1H2AH,UNC13B,TUBB,HIST2H2AA3,HIST1H2AM,HIST1H2AB,HIST1H2AC,CLNS1A,BCS1L,DDX23,	9.69E-10
GO:0034621	cellular macromolecular complex subunit organization	RPS14,RPS15,FKBP4,HIST1H1E,TUBB4B,TUBB3,DIAPH1,HIST1H2AE,TFAM,HIST1H4C,H1FX,MBNL1,WASL,RPL24,EIF6,NUP205,IPO4,PFDN6,KIF2C,HIST1H3D,SMAD4,ARL2,ADRM1,IPO7,SNRPE,XPO1,TUBB2B,FLNA,IPO5,TSR1,TNPO1,SHPRH,SF3A3,COX18,ARID1A,TUBA1C,PXN,CHAF1A,KPNB1,GEMIN6,NPM1,SRSF5,FKBP1A,HIST1H2AH,UNC13B,TUBB,HIST2H2AA3,HIST1H2AM,HIST1H2AB,HIST1H2AC,CLNS1A,BCS1L,DDX23,	1.85E-9
GO:0006396	RNA processing	CPSF6,PPAN,CCAR1,EFTUD2,HNRPLL,POLR2I,KHSRP,ELAC2,RPS14,RPS15,RNPS1,KHDRBS1,MBNL1,POLR2L,HEATR1,JMJD6,ATXN1,SF3B3,PA2G4,DHX16,U2AF2,DEDD2,QTRT1,DDX5,FTSJ1,HNRNPF,DHX8,HNRNPA2B1,TRMT61A,SREK1IP1,SMC1A,CD2BP2,SRRT,SNRPE,PABPN1,DDX17,EXOSC6,LSM7,HSD17B10,RBM10,SF3A3,PPP2R1A,POP4,DUSP11,NHP2L1,DDX56,HNRNPM,RPL11,GEMIN6,SNRNP70,SCAF8,SRSF5,DDX39A,SART3,PCBP2,PPIL1,PTBP1,RPS28,RRP9,RPS24,SUGP1,CSTF2T,PRPF8,CLNS1A,DDX23,	1.59E-8
GO:0046907	intracellular transport	TAOK2,MFN2,RPS15,WDR19,CUX1,FGF2,SNX9,BAK1,OPTN,RHOT2,TRAPPC2,SRPR,RAB8A,BID,CDC37,ATXN1,ARCN1,GOLGA3,IPO4,NUP205,ARRB1,NPC2,AP2B1,UCHL1,ARF1,RFFL,MYO6,KIF1A,KLC2,GGA2,DOPEY2,YWHAQ,IPO7,XPO1,UPF2,ERGIC2,GSK3B,FLNA,STX3,PABPN1,HSPA8,IPO5,AP3D1,DNM2,ERGIC1,TNPO1,KPNA6,CSPG5,RAB11A,MLX,KDELR1,MYL6,RPAIN,GABARAPL2,TOM1L1,NUP155,SEC24A,MYBBP1A,ZFYVE20,RPL11,KPNB1,NPM1,KPNA3,KPNA2,DDX39A,RANBP2,COPG,MYH2,MACF1,MYH9,CLTC,ZFYVE16,XPOT,	2.99E-8
GO:0016071	mRNA metabolic process	CPSF6,CCAR1,EFTUD2,KHSRP,POLR2I,HNRPLL,RNPS1,KHDRBS1,MBNL1,POLR2L,HSPA1B,JMJD6,EIF2C1,SF3B3,DHX16,U2AF2,DDX5,HNRNPF,RNH1,DHX8,HNRNPA2B1,SREK1IP1,SMC1A,CD2BP2,SNRPE,UPF2,PABPN1,LSM7,RBM10,SF3A3,BRF1,POP4,NHP2L1,HNRNPM,GEMIN6,SRSF5,SNRNP70,SCAF8,DDX39A,DCP2,PCBP2,EIF2C4,PPIL1,PTBP1,SUGP1,CSTF2T,PRPF8,CLNS1A,DDX23,	4.70E-8
GO:0000398	nuclear mRNA splicing, via spliceosome	SMC1A,CD2BP2,CCAR1,SNRPE,EFTUD2,POLR2I,PABPN1,LSM7,SF3A3,RNPS1,MBNL1,POLR2L,NHP2L1,HNRNPM,GEMIN6,SRSF5,SNRNP70,DDX39A,PCBP2,SF3B3,PTBP1,SUGP1,U2AF2,HNRNPF,PRPF8,HNRNPA2B1,CLNS1A,DDX23,	9.93E-8
GO:0000375	RNA splicing, via transesterification reactions	SMC1A,CD2BP2,CCAR1,SNRPE,EFTUD2,POLR2I,PABPN1,LSM7,SF3A3,RNPS1,MBNL1,POLR2L,NHP2L1,HNRNPM,GEMIN6,SRSF5,SNRNP70,DDX39A,PCBP2,SF3B3,PTBP1,SUGP1,U2AF2,HNRNPF,PRPF8,HNRNPA2B1,CLNS1A,DDX23,	9.93E-8
GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	SMC1A,CD2BP2,CCAR1,SNRPE,EFTUD2,POLR2I,PABPN1,LSM7,SF3A3,RNPS1,MBNL1,POLR2L,NHP2L1,HNRNPM,GEMIN6,SRSF5,SNRNP70,DDX39A,PCBP2,SF3B3,PTBP1,SUGP1,U2AF2,HNRNPF,PRPF8,HNRNPA2B1,CLNS1A,DDX23,	9.93E-8
GO:0070271	protein complex biogenesis	GCHFR,POLR2I,FKBP4,TUBB4B,IGF1R,TUBB3,DIAPH1,TFAM,RAD51,SKI,TCEB2,POLR2L,WASL,ITPR3,ATG16L1,TP63,MDM2,SF3B3,IPO4,NUP205,PFDN6,PEBP1,LAMC1,CD2AP,SMAD4,ARL2,ADRM1,IPO7,XPO1,IKBKAP,TUBB2B,NACC2,RRM1,FLNA,IPO5,TNPO1,HSD17B10,PFKM,CDK9,MDN1,PPP2R1A,BRF1,GPX3,COX18,TUBA1C,IRAK1,PXN,TUBGCP2,CHAF1A,KPNB1,KPNA3,NPM1,FKBP1A,MED16,UNC13B,TUBB,BCS1L,CDH1,	3.41E-7
GO:0006461	protein complex assembly	GCHFR,POLR2I,FKBP4,TUBB4B,IGF1R,TUBB3,DIAPH1,TFAM,RAD51,SKI,TCEB2,POLR2L,WASL,ITPR3,ATG16L1,TP63,MDM2,SF3B3,IPO4,NUP205,PFDN6,PEBP1,LAMC1,CD2AP,SMAD4,ARL2,ADRM1,IPO7,XPO1,IKBKAP,TUBB2B,NACC2,RRM1,FLNA,IPO5,TNPO1,HSD17B10,PFKM,CDK9,MDN1,PPP2R1A,BRF1,GPX3,COX18,TUBA1C,IRAK1,PXN,TUBGCP2,CHAF1A,KPNB1,KPNA3,NPM1,FKBP1A,MED16,UNC13B,TUBB,BCS1L,CDH1,	3.41E-7
GO:0006397	mRNA processing	SMC1A,CPSF6,CCAR1,CD2BP2,EFTUD2,SNRPE,HNRPLL,POLR2I,KHSRP,PABPN1,LSM7,RBM10,SF3A3,RNPS1,POP4,KHDRBS1,MBNL1,NHP2L1,POLR2L,HNRNPM,JMJD6,GEMIN6,SNRNP70,SCAF8,SRSF5,DDX39A,PCBP2,SF3B3,PPIL1,PTBP1,DHX16,SUGP1,U2AF2,CSTF2T,DDX5,HNRNPF,PRPF8,DHX8,HNRNPA2B1,CLNS1A,SREK1IP1,DDX23,	6.88E-7
GO:0031398	positive regulation of protein ubiquitination	PSMD11,PSMD2,PSMD3,BTRC,PSMC3,UBB,DNAJA3,PSMA4,PSMB6,CDK1,PSMA7,PSMF1,PSMB1,FKBP1A,AXIN1,CDC20,PLK1,CCNB1,SMAD7,	7.26E-7
GO:0010605	negative regulation of macromolecule metabolic process	MEF2C,CSDA,MECP2,STAT3,SUPT5H,RNF128,HES1,HMGB1,PRKCA,CBX2,RPS14,PSMA4,CD276,CUX1,PSMF1,CBX5,SIN3B,FGF2,KDM6B,SKI,TRIM28,BAK1,KHDRBS1,BTAF1,GATAD2A,PSMD2,PSMD3,EIF2C1,ATXN1,TP63,PSMC3,MDM2,UBB,PSMB6,PA2G4,PEBP1,PSMA7,PSMB1,DEDD2,MEN1,SMAD4,ENO1,NFKB1,RBBP7,PSMD11,YWHAQ,SRRT,SIN3A,NACC2,FLNA,MLX,SPEN,RNF2,PPP2R1A,TBL1X,ZNF174,SAP30,SMAD7,GABPA,TERF2,NPM1,EIF2C4,HSP90AB1,PPARD,PHF12,GTPBP4,FKBP1A,PURB,CBFA2T2,EIF2AK1,CDC20,NAB1,HDAC1,THBS1,	1.10E-6
GO:0022403	cell cycle phase	RCC1,PPP6C,CDK1,TUBB3,RAD51,KHDRBS1,CUL5,MDM2,RPL24,AURKB,KIF2C,NEK2,ATM,CD2AP,PRC1,SMC1A,RCC2,ZWINT,NCAPH,TUBB2B,MAPRE1,DNM2,CDKN3,VCPIP1,SMC3,STAG1,PLK1,USP9X,CCND1,POLE,KPNA2,CHEK1,KIFC1,E4F1,WEE1,CIT,DYNC1H1,CDC25A,MKI67,MYH9,CDC20,TUBB,MAU2,CCNB1,HAUS1,PDS5B,CCNE1,NEK6,CDK11A,	1.37E-6
GO:0008380	RNA splicing	SMC1A,CCAR1,PPAN,CD2BP2,EFTUD2,SNRPE,POLR2I,KHSRP,PABPN1,LSM7,RBM10,SF3A3,RNPS1,PPP2R1A,MBNL1,POLR2L,NHP2L1,HNRNPM,JMJD6,GEMIN6,SNRNP70,SRSF5,DDX39A,PCBP2,SF3B3,PPIL1,PTBP1,DHX16,SUGP1,U2AF2,DDX5,HNRNPF,PRPF8,DHX8,HNRNPA2B1,CLNS1A,SREK1IP1,DDX23,	1.49E-6
GO:0031396	regulation of protein ubiquitination	PSMD11,PSMD2,PSMD3,BTRC,PSMC3,UBB,DNAJA3,PSMA4,PSMB6,CDK1,GTPBP4,PSMA7,PSMF1,PSMB1,FKBP1A,AXIN1,PLK1,CDC20,CCNB1,SMAD7,	2.48E-6
GO:0044265	cellular macromolecule catabolic process	BRCC3,MPG,RNF128,HERC1,PSMA4,CDK1,PSMF1,KLHL15,RNF123,USP10,RNPS1,UBR1,RAD23B,USP13,KLHL36,RPA2,TCEB2,HSPA1B,PSMD2,PSMD3,EIF2C1,CUL5,PSMC3,MDM2,UBB,FBXL19,PSMB6,PSMA7,UBE2R2,PSMB1,UCHL1,DEDD2,RFFL,ATM,CD2AP,UFSP2,RNH1,NFKB1,PSMD11,UPF2,BTRC,ERAP1,UBE2H,SHPRH,LDLR,RNF2,VCPIP1,UBE4B,C10orf46,TBL1X,USP9X,TOM1L1,RBX1,TRIP12,NPLOC4,HSP90B1,KLHL3,AUP1,RNF40,DTL,E4F1,MYLIP,DCP2,EIF2C4,RANBP2,NTHL1,FBXO45,MYH9,CDC20,CCNB1,FAF1,USP31,	2.75E-6
GO:0022613	ribonucleoprotein complex biogenesis	SNRPE,TSR1,EXOSC6,RPS14,RPS15,SF3A3,POP4,MBNL1,MINA,NHP2L1,DDX56,HEATR1,RPL11,GEMIN6,RPL7A,NPM1,SRSF5,SURF6,RPL24,EIF6,PA2G4,RPS28,RRP9,RPS24,GTPBP4,FTSJ1,CLNS1A,DDX23,	2.76E-6
GO:0009057	macromolecule catabolic process	BRCC3,MPG,RNF128,HERC1,PSMA4,CDK1,PSMF1,KLHL15,RNF123,RNPS1,USP10,UBR1,RAD23B,USP13,KLHL36,RPA2,TCEB2,HSPA1B,PSMD2,PSMD3,EIF2C1,CUL5,PSMC3,MDM2,UBB,FBXL19,PSMB6,DHCR24,PSMA7,UBE2R2,PSMB1,UCHL1,DEDD2,AXIN1,RFFL,PYGL,ATM,CD2AP,UFSP2,RNH1,NFKB1,PSMD11,UPF2,BTRC,ERAP1,UBE2H,SHPRH,LDLR,RNF2,VCPIP1,UBE4B,C10orf46,TBL1X,USP9X,RBX1,TOM1L1,TRIP12,NPLOC4,HSP90B1,KLHL3,AUP1,RNF40,DTL,E4F1,MYLIP,DCP2,EIF2C4,RANBP2,NTHL1,FBXO45,FKBP1A,MYH9,CDC20,CCNB1,FAF1,USP31,	2.97E-6
GO:0000087	M phase of mitotic cell cycle	SMC1A,RCC2,ZWINT,TUBB2B,NCAPH,RCC1,MAPRE1,CDK1,TUBB3,VCPIP1,SMC3,STAG1,PLK1,USP9X,E4F1,KIFC1,WEE1,RPL24,CIT,AURKB,KIF2C,CDC25A,CDC20,NEK2,MAU2,TUBB,CD2AP,PDS5B,CCNB1,HAUS1,NEK6,CDK11A,	2.97E-6
GO:0006511	ubiquitin-dependent protein catabolic process	PSMD11,BTRC,UBE2H,PSMA4,CDK1,PSMF1,USP10,C10orf46,UBE4B,TBL1X,UBR1,RAD23B,USP9X,USP13,TOM1L1,NPLOC4,HSP90B1,RNF40,PSMD2,PSMD3,CUL5,MDM2,PSMC3,UBB,PSMB6,PSMA7,PSMB1,UCHL1,CDC20,CD2AP,CCNB1,FAF1,USP31,	5.52E-6
GO:0007067	mitosis	SMC1A,RCC2,ZWINT,TUBB2B,NCAPH,RCC1,MAPRE1,CDK1,TUBB3,VCPIP1,SMC3,STAG1,PLK1,USP9X,E4F1,KIFC1,WEE1,CIT,AURKB,KIF2C,CDC25A,CDC20,NEK2,MAU2,TUBB,CD2AP,PDS5B,CCNB1,HAUS1,NEK6,CDK11A,	5.80E-6
GO:0000280	nuclear division	SMC1A,RCC2,ZWINT,TUBB2B,NCAPH,RCC1,MAPRE1,CDK1,TUBB3,VCPIP1,SMC3,STAG1,PLK1,USP9X,E4F1,KIFC1,WEE1,CIT,AURKB,KIF2C,CDC25A,CDC20,NEK2,MAU2,TUBB,CD2AP,PDS5B,CCNB1,HAUS1,NEK6,CDK11A,	5.80E-6
GO:0006325	chromatin organization	BRCC3,SUPT5H,HMGB1,EP300,CBX2,RUVBL2,C20orf20,KAT2A,HIST1H1E,SHPRH,CBX5,MSL3,RNF2,HIST1H2AE,CBX6,ATXN7,HIST1H4C,ARID1A,KDM6B,H1FX,RNF40,ARID1B,TERF2,CHAF1A,JMJD6,KAT2B,NPM1,SETD1B,ARID4B,SAFB,WHSC1,DOT1L,MLL2,SETDB1,CARM1,HIST1H3D,HIST1H2AH,HIST2H2AA3,HDAC1,MEN1,SMARCD2,HIST1H2AM,KDM3B,HIST1H2AB,HIST1H2AC,RBBP7,	7.96E-6
GO:0000279	M phase	RCC2,SMC1A,ZWINT,TUBB2B,NCAPH,RCC1,MAPRE1,CDK1,TUBB3,VCPIP1,SMC3,STAG1,PLK1,USP9X,RAD51,KPNA2,CHEK1,E4F1,KIFC1,WEE1,RPL24,DYNC1H1,CIT,AURKB,KIF2C,CDC25A,MKI67,MYH9,NEK2,CDC20,ATM,MAU2,TUBB,CD2AP,PDS5B,CCNB1,HAUS1,PRC1,NEK6,CDK11A,	8.01E-6
GO:0051276	chromosome organization	BRCC3,SUPT5H,HMGB1,CBX2,RUVBL2,KAT2A,HIST1H1E,CBX5,HIST1H2AE,ATXN7,CBX6,HIST1H4C,KDM6B,H1FX,ARID1B,JMJD6,SETD1B,SAFB,DOT1L,SETDB1,HIST1H3D,NEK2,SMARCD2,MEN1,RBBP7,SMC1A,ZWINT,NCAPH,EP300,C20orf20,SHPRH,MSL3,RNF2,SMC3,ARID1A,RNF40,TERF2,CHAF1A,KAT2B,NPM1,KIFC1,ARID4B,WHSC1,MLL2,CARM1,HIST1H2AH,HIST2H2AA3,HDAC1,MAU2,HIST1H2AM,KDM3B,PDS5B,HIST1H2AB,HIST1H2AC,	1.10E-5
GO:0043623	cellular protein complex assembly	IPO7,XPO1,TUBB2B,FLNA,IPO5,TNPO1,FKBP4,TUBB4B,DIAPH1,TUBB3,TFAM,TUBA1C,COX18,PXN,KPNB1,NUP205,IPO4,PFDN6,FKBP1A,UNC13B,TUBB,SMAD4,ARL2,ADRM1,BCS1L,	1.21E-5
GO:0048285	organelle fission	SMC1A,RCC2,ZWINT,TUBB2B,NCAPH,RCC1,MAPRE1,CDK1,TUBB3,VCPIP1,SMC3,STAG1,PLK1,USP9X,E4F1,KIFC1,WEE1,CIT,AURKB,KIF2C,CDC25A,CDC20,NEK2,MAU2,TUBB,CD2AP,PDS5B,CCNB1,HAUS1,NEK6,CDK11A,	1.29E-5
GO:0010498	proteasomal protein catabolic process	PSMD11,PSMD2,PSMD3,PSMC3,UBB,PSMB6,PSMA4,CDK1,PSMA7,PSMF1,PSMB1,TBL1X,CDC20,RAD23B,CD2AP,CCNB1,NPLOC4,FAF1,HSP90B1,	1.33E-5
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	PSMD11,PSMD2,PSMD3,PSMC3,UBB,PSMB6,PSMA4,CDK1,PSMA7,PSMF1,PSMB1,TBL1X,CDC20,RAD23B,CD2AP,CCNB1,NPLOC4,FAF1,HSP90B1,	1.33E-5
GO:0042254	ribosome biogenesis	DDX56,HEATR1,RPL11,NPM1,RPL7A,SURF6,RPL24,TSR1,EXOSC6,RPS14,EIF6,RPS15,PA2G4,RPS28,RRP9,GTPBP4,RPS24,FTSJ1,POP4,MINA,NHP2L1,	1.41E-5
GO:0006913	nucleocytoplasmic transport	IPO7,MYBBP1A,KPNB1,XPO1,KPNA3,NPM1,UPF2,KPNA2,GSK3B,DDX39A,ATXN1,PABPN1,IPO5,TNPO1,KPNA6,RPS15,NUP205,IPO4,RANBP2,MLX,FGF2,RPAIN,XPOT,NUP155,	1.98E-5
GO:0051437	positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	PSMD11,PSMD2,PSMD3,BTRC,PSMC3,UBB,PSMA4,PSMB6,CDK1,PSMA7,PSMF1,PSMB1,CDC20,PLK1,CCNB1,	2.00E-5
GO:0051438	regulation of ubiquitin-protein ligase activity	PSMD11,PSMD2,PSMD3,BTRC,PSMC3,UBB,PSMA4,PSMB6,CDK1,PSMA7,PSMF1,PSMB1,CDC20,PLK1,CCNB1,SMAD7,	2.41E-5
GO:0051169	nuclear transport	IPO7,MYBBP1A,KPNB1,XPO1,KPNA3,NPM1,UPF2,KPNA2,GSK3B,DDX39A,ATXN1,PABPN1,IPO5,TNPO1,KPNA6,RPS15,NUP205,IPO4,RANBP2,MLX,FGF2,RPAIN,XPOT,NUP155,	2.44E-5
GO:0032268	regulation of cellular protein metabolic process	CPEB2,PRKCA,PSMA4,CDK1,PSMF1,FGF2,EIF3K,EIF4B,PKN1,BAK1,PSMD2,PSMD3,EIF2C1,MDM2,PSMC3,UBB,PSMB6,PA2G4,MAP3K6,PEBP1,EIF4G2,PSMA7,PSMB1,AXIN1,MEN1,CBS,SMAD4,NFKB1,RPS5,PSMD11,EP300,BTRC,DNAJA3,MKNK2,PPP2R1A,PLK1,EIF2B2,HIPK3,SMAD7,CCND1,BMPR2,EIF3B,EIF2C4,HSP90AB1,GTPBP4,FKBP1A,EIF2AK1,CDC20,CCNB1,THBS1,	2.57E-5
GO:0051443	positive regulation of ubiquitin-protein ligase activity	PSMD11,PSMD2,PSMD3,BTRC,PSMC3,UBB,PSMA4,PSMB6,CDK1,PSMA7,PSMF1,PSMB1,CDC20,PLK1,CCNB1,	2.83E-5
GO:0051253	negative regulation of RNA metabolic process	MEF2C,YWHAQ,CSDA,SIN3A,MECP2,STAT3,SUPT5H,HES1,HMGB1,CBX2,RPS14,MLX,CUX1,SIN3B,CBX5,RNF2,SPEN,FGF2,TBL1X,KDM6B,SKI,ZNF174,TRIM28,SAP30,SMAD7,GATAD2A,GABPA,NPM1,TP63,MDM2,PPARD,PA2G4,PHF12,PURB,CBFA2T2,HDAC1,MEN1,SMAD4,ENO1,NFKB1,RBBP7,	3.22E-5
GO:0051439	regulation of ubiquitin-protein ligase activity during mitotic cell cycle	PSMD11,PSMD2,PSMD3,BTRC,PSMC3,UBB,PSMA4,PSMB6,CDK1,PSMA7,PSMF1,PSMB1,CDC20,PLK1,CCNB1,	3.34E-5
GO:0051603	proteolysis involved in cellular protein catabolic process	BRCC3,RNF128,HERC1,PSMA4,CDK1,PSMF1,RNF123,KLHL15,USP10,RAD23B,UBR1,USP13,KLHL36,TCEB2,PSMD2,PSMD3,CUL5,PSMC3,MDM2,FBXL19,UBB,PSMB6,PSMA7,PSMB1,UBE2R2,UCHL1,RFFL,CD2AP,UFSP2,NFKB1,PSMD11,BTRC,ERAP1,UBE2H,SHPRH,RNF2,VCPIP1,UBE4B,C10orf46,TBL1X,USP9X,TOM1L1,RBX1,TRIP12,NPLOC4,KLHL3,HSP90B1,AUP1,RNF40,DTL,E4F1,MYLIP,RANBP2,FBXO45,MYH9,CDC20,CCNB1,FAF1,USP31,	3.48E-5
GO:0051340	regulation of ligase activity	PSMD11,PSMD2,PSMD3,BTRC,PSMC3,UBB,PSMA4,PSMB6,CDK1,PSMA7,PSMF1,PSMB1,CDC20,PLK1,CCNB1,SMAD7,	3.84E-5
GO:0044257	cellular protein catabolic process	BRCC3,RNF128,HERC1,PSMA4,CDK1,PSMF1,RNF123,KLHL15,USP10,RAD23B,UBR1,USP13,KLHL36,TCEB2,PSMD2,PSMD3,CUL5,PSMC3,MDM2,FBXL19,UBB,PSMB6,PSMA7,PSMB1,UBE2R2,UCHL1,RFFL,CD2AP,UFSP2,NFKB1,PSMD11,BTRC,ERAP1,UBE2H,SHPRH,RNF2,VCPIP1,UBE4B,C10orf46,TBL1X,USP9X,TOM1L1,RBX1,TRIP12,NPLOC4,KLHL3,HSP90B1,AUP1,RNF40,DTL,E4F1,MYLIP,RANBP2,FBXO45,MYH9,CDC20,CCNB1,FAF1,USP31,	3.94E-5
GO:0051351	positive regulation of ligase activity	PSMD11,PSMD2,PSMD3,BTRC,PSMC3,UBB,PSMA4,PSMB6,CDK1,PSMA7,PSMF1,PSMB1,CDC20,PLK1,CCNB1,	4.62E-5
GO:0051248	negative regulation of protein metabolic process	PSMD11,PRKCA,FLNA,PSMA4,PSMF1,PPP2R1A,BAK1,SMAD7,PSMD2,PSMD3,EIF2C1,PSMC3,EIF2C4,UBB,HSP90AB1,PSMB6,PEBP1,GTPBP4,PSMA7,PSMB1,FKBP1A,EIF2AK1,CDC20,MEN1,NFKB1,THBS1,	4.78E-5
GO:0045892	negative regulation of transcription, DNA-dependent	MEF2C,YWHAQ,CSDA,SIN3A,MECP2,STAT3,SUPT5H,HES1,HMGB1,CBX2,RPS14,MLX,CUX1,SIN3B,CBX5,RNF2,SPEN,FGF2,TBL1X,KDM6B,SKI,ZNF174,TRIM28,SAP30,SMAD7,GATAD2A,GABPA,TP63,MDM2,PPARD,PA2G4,PHF12,PURB,CBFA2T2,HDAC1,MEN1,SMAD4,ENO1,NFKB1,RBBP7,	4.89E-5
GO:0030163	protein catabolic process	BRCC3,RNF128,HERC1,PSMA4,CDK1,PSMF1,RNF123,KLHL15,USP10,RAD23B,UBR1,USP13,KLHL36,TCEB2,PSMD2,PSMD3,CUL5,PSMC3,MDM2,FBXL19,UBB,PSMB6,PSMA7,PSMB1,UBE2R2,UCHL1,AXIN1,RFFL,CD2AP,UFSP2,NFKB1,PSMD11,BTRC,ERAP1,UBE2H,SHPRH,RNF2,VCPIP1,UBE4B,C10orf46,TBL1X,USP9X,TOM1L1,RBX1,TRIP12,NPLOC4,KLHL3,HSP90B1,AUP1,RNF40,DTL,E4F1,MYLIP,RANBP2,FBXO45,MYH9,CDC20,CCNB1,FAF1,USP31,	5.08E-5
GO:0034613	cellular protein localization	YWHAQ,IPO7,XPO1,TAOK2,GSK3B,FLNA,STX3,AP3D1,IPO5,TNPO1,KPNA6,MFN2,WDR19,RAB11A,KDELR1,RPAIN,FGF2,TOM1L1,COX18,SNX9,OPTN,SEC24A,SRPR,TERF2,RPL11,KPNB1,BID,NPM1,KPNA3,KPNA2,CDC37,ARCN1,IPO4,NUP205,RANBP2,COPG,MACF1,AP2B1,AURKB,RFFL,ZFYVE16,CLTC,MYO6,GGA2,	6.04E-5
GO:0009890	negative regulation of biosynthetic process	MEF2C,CSDA,GCHFR,STAT3,MECP2,SUPT5H,HES1,PRKCA,HMGB1,CBX2,RNF128,RPS14,CD276,CUX1,SIN3B,CBX5,FGF2,KDM6B,SKI,TRIM28,KHDRBS1,BTAF1,GATAD2A,EIF2C1,ATXN1,TP63,MDM2,ATP1A1,PA2G4,DEDD2,MEN1,SMAD4,ENO1,NFKB1,RBBP7,YWHAQ,SIN3A,NACC2,MLX,RNF2,SPEN,TBL1X,ZNF174,SAP30,SMAD7,GABPA,TERF2,EIF2C4,PPARD,PHF12,GTPBP4,PURB,CBFA2T2,EIF2AK1,HDAC1,NAB1,	6.52E-5
GO:0043632	modification-dependent macromolecule catabolic process	BRCC3,RNF128,HERC1,PSMA4,CDK1,PSMF1,RNF123,KLHL15,USP10,RAD23B,UBR1,USP13,KLHL36,TCEB2,PSMD2,PSMD3,CUL5,PSMC3,MDM2,FBXL19,UBB,PSMB6,PSMA7,PSMB1,UBE2R2,UCHL1,RFFL,CD2AP,UFSP2,PSMD11,BTRC,UBE2H,SHPRH,RNF2,VCPIP1,UBE4B,C10orf46,TBL1X,USP9X,TOM1L1,RBX1,TRIP12,NPLOC4,KLHL3,HSP90B1,AUP1,RNF40,DTL,E4F1,MYLIP,RANBP2,FBXO45,CDC20,CCNB1,FAF1,USP31,	6.94E-5
GO:0019941	modification-dependent protein catabolic process	BRCC3,RNF128,HERC1,PSMA4,CDK1,PSMF1,RNF123,KLHL15,USP10,RAD23B,UBR1,USP13,KLHL36,TCEB2,PSMD2,PSMD3,CUL5,PSMC3,MDM2,FBXL19,UBB,PSMB6,PSMA7,PSMB1,UBE2R2,UCHL1,RFFL,CD2AP,UFSP2,PSMD11,BTRC,UBE2H,SHPRH,RNF2,VCPIP1,UBE4B,C10orf46,TBL1X,USP9X,TOM1L1,RBX1,TRIP12,NPLOC4,KLHL3,HSP90B1,AUP1,RNF40,DTL,E4F1,MYLIP,RANBP2,FBXO45,CDC20,CCNB1,FAF1,USP31,	6.94E-5
GO:0010558	negative regulation of macromolecule biosynthetic process	MEF2C,CSDA,STAT3,MECP2,SUPT5H,HES1,PRKCA,HMGB1,CBX2,RNF128,RPS14,CD276,CUX1,SIN3B,CBX5,FGF2,KDM6B,SKI,TRIM28,KHDRBS1,BTAF1,GATAD2A,EIF2C1,ATXN1,TP63,MDM2,PA2G4,DEDD2,MEN1,SMAD4,ENO1,NFKB1,RBBP7,YWHAQ,SIN3A,NACC2,MLX,RNF2,SPEN,TBL1X,ZNF174,SAP30,SMAD7,GABPA,TERF2,EIF2C4,PPARD,PHF12,GTPBP4,PURB,CBFA2T2,EIF2AK1,HDAC1,NAB1,	7.00E-5
GO:0032269	negative regulation of cellular protein metabolic process	PSMD11,PRKCA,PSMA4,PSMF1,PPP2R1A,BAK1,SMAD7,PSMD2,PSMD3,EIF2C1,PSMC3,UBB,HSP90AB1,EIF2C4,PSMB6,PEBP1,GTPBP4,PSMA7,PSMB1,FKBP1A,EIF2AK1,CDC20,MEN1,NFKB1,THBS1,	7.03E-5
GO:0031327	negative regulation of cellular biosynthetic process	MEF2C,CSDA,STAT3,MECP2,SUPT5H,HES1,PRKCA,HMGB1,CBX2,RNF128,RPS14,CD276,CUX1,SIN3B,CBX5,FGF2,KDM6B,SKI,TRIM28,KHDRBS1,BTAF1,GATAD2A,EIF2C1,ATXN1,TP63,ATP1A1,MDM2,PA2G4,DEDD2,MEN1,SMAD4,ENO1,NFKB1,RBBP7,YWHAQ,SIN3A,NACC2,MLX,RNF2,SPEN,TBL1X,ZNF174,SAP30,SMAD7,GABPA,TERF2,EIF2C4,PPARD,PHF12,GTPBP4,PURB,CBFA2T2,EIF2AK1,HDAC1,NAB1,	7.15E-5
GO:0070727	cellular macromolecule localization	YWHAQ,IPO7,XPO1,TAOK2,GSK3B,FLNA,STX3,AP3D1,IPO5,TNPO1,KPNA6,MFN2,WDR19,RAB11A,KDELR1,RPAIN,FGF2,TOM1L1,COX18,SNX9,OPTN,SEC24A,SRPR,TERF2,RPL11,KPNB1,BID,NPM1,KPNA3,KPNA2,CDC37,ARCN1,IPO4,NUP205,RANBP2,COPG,MACF1,AP2B1,AURKB,RFFL,ZFYVE16,CLTC,MYO6,GGA2,	7.17E-5
GO:0007017	microtubule-based process	SMC1A,ZWINT,TUBB2B,RCC1,DYNLL1,TTL,TUBB4B,TUBB3,SMC3,TUBA1C,KIF20A,MAP1B,RHOT2,KIF18B,TUBGCP2,STMN3,NPM1,KPNA2,KIFC1,PPP4C,DYNC1H1,MACF1,UCHL1,KIF2C,MYH9,NEK2,TUBB,KIF1A,HAUS1,KLC2,PRC1,	8.72E-5
GO:0042255	ribosome assembly	NPM1,RPL24,EIF6,TSR1,RPS14,RPS15,	1.09E-4
GO:0031400	negative regulation of protein modification process	PSMD11,PSMD2,PSMD3,PRKCA,PSMC3,UBB,PSMA4,PSMB6,PEBP1,GTPBP4,PSMA7,PSMF1,PSMB1,FKBP1A,PPP2R1A,CDC20,MEN1,BAK1,SMAD7,	1.10E-4
GO:0051301	cell division	SMC1A,RCC2,ZWINT,NCAPH,RCC1,MAPRE1,ANXA11,CDK1,PDCD6IP,SMC3,STAG1,PLK1,USP9X,CCND1,E4F1,KIFC1,WEE1,CIT,RASA1,AURKB,CDC25A,MYH9,PPP1CC,CDC20,NEK2,MAU2,CD2AP,PDS5B,HAUS1,CCNB1,PRC1,CCNE1,NEK6,CDK11A,	1.23E-4
GO:0031401	positive regulation of protein modification process	PSMD11,PRKCA,BTRC,DNAJA3,PSMA4,CDK1,PSMF1,FGF2,PLK1,SMAD7,BMPR2,CCND1,PSMD2,PSMD3,PSMC3,UBB,PSMB6,PSMA7,FKBP1A,PSMB1,AXIN1,CDC20,MEN1,SMAD4,CCNB1,	1.29E-4
GO:0006886	intracellular protein transport	YWHAQ,IPO7,XPO1,TAOK2,GSK3B,STX3,AP3D1,IPO5,TNPO1,KPNA6,MFN2,WDR19,RAB11A,KDELR1,FGF2,RPAIN,TOM1L1,SNX9,OPTN,SEC24A,SRPR,RPL11,KPNB1,BID,NPM1,KPNA3,KPNA2,CDC37,ARCN1,IPO4,NUP205,RANBP2,COPG,MACF1,AP2B1,RFFL,ZFYVE16,CLTC,MYO6,GGA2,	1.42E-4
GO:0016481	negative regulation of transcription	MEF2C,YWHAQ,CSDA,SIN3A,MECP2,STAT3,SUPT5H,HES1,HMGB1,CBX2,NACC2,RPS14,MLX,CUX1,SIN3B,CBX5,RNF2,SPEN,FGF2,TBL1X,KDM6B,SKI,ZNF174,TRIM28,SAP30,KHDRBS1,SMAD7,GATAD2A,BTAF1,GABPA,ATXN1,TP63,MDM2,PPARD,PA2G4,PHF12,PURB,DEDD2,CBFA2T2,NAB1,HDAC1,MEN1,SMAD4,ENO1,NFKB1,RBBP7,	1.86E-4
GO:0000059	protein import into nucleus, docking	IPO7,KPNB1,XPO1,IPO5,TNPO1,IPO4,NUP205,	2.23E-4
GO:0010629	negative regulation of gene expression	MEF2C,CSDA,STAT3,MECP2,SUPT5H,HES1,HMGB1,CBX2,RPS14,CUX1,SIN3B,CBX5,FGF2,KDM6B,SKI,TRIM28,KHDRBS1,BTAF1,GATAD2A,EIF2C1,ATXN1,TP63,MDM2,PA2G4,DEDD2,MEN1,SMAD4,ENO1,NFKB1,RBBP7,YWHAQ,SIN3A,SRRT,NACC2,MLX,RNF2,SPEN,TBL1X,ZNF174,SAP30,SMAD7,GABPA,EIF2C4,PPARD,PHF12,PURB,CBFA2T2,HDAC1,NAB1,	2.30E-4
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	PSMD11,PSMD2,PSMD3,PSMC3,UBB,PSMA4,PSMB6,CDK1,PSMA7,PSMF1,PSMB1,CDC20,CCNB1,	2.32E-4
GO:0051247	positive regulation of protein metabolic process	PSMD11,PRKCA,EP300,BTRC,DNAJA3,PSMA4,CDK1,PSMF1,FGF2,PLK1,SMAD7,BMPR2,CCND1,PSMD2,PSMD3,MDM2,PSMC3,UBB,PSMB6,PSMA7,FKBP1A,PSMB1,AXIN1,CDC20,MEN1,SMAD4,CCNB1,EGLN2,THBS1,	2.41E-4
GO:0031399	regulation of protein modification process	PSMD11,PRKCA,BTRC,DNAJA3,PSMA4,CDK1,PSMF1,FGF2,PPP2R1A,PLK1,PKN1,BAK1,HIPK3,SMAD7,BMPR2,CCND1,PSMD2,PSMD3,PSMC3,UBB,PSMB6,MAP3K6,PEBP1,GTPBP4,PSMA7,FKBP1A,PSMB1,AXIN1,CDC20,MEN1,CBS,SMAD4,CCNB1,	2.73E-4
GO:0032270	positive regulation of cellular protein metabolic process	PSMD11,PRKCA,EP300,BTRC,DNAJA3,PSMA4,CDK1,PSMF1,FGF2,PLK1,SMAD7,BMPR2,CCND1,PSMD2,PSMD3,MDM2,PSMC3,UBB,PSMB6,PSMA7,FKBP1A,PSMB1,AXIN1,CDC20,MEN1,SMAD4,CCNB1,THBS1,	2.81E-4
GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	MEF2C,CSDA,STAT3,MECP2,SUPT5H,HES1,HMGB1,CBX2,RPS14,CUX1,SIN3B,CBX5,FGF2,KDM6B,SKI,TRIM28,KHDRBS1,BTAF1,GATAD2A,ATXN1,TP63,MDM2,PA2G4,DEDD2,MEN1,SMAD4,ENO1,NFKB1,RBBP7,YWHAQ,SIN3A,NACC2,MLX,RNF2,SPEN,TBL1X,ZNF174,SAP30,SMAD7,TERF2,GABPA,NPM1,PPARD,PHF12,GTPBP4,PURB,CBFA2T2,HDAC1,NAB1,	3.31E-4
GO:0022618	ribonucleoprotein complex assembly	SNRPE,GEMIN6,NPM1,SRSF5,RPL24,EIF6,RPS14,TSR1,RPS15,SF3A3,CLNS1A,DDX23,MBNL1,	4.14E-4
GO:0051172	negative regulation of nitrogen compound metabolic process	MEF2C,CSDA,STAT3,MECP2,SUPT5H,HES1,HMGB1,CBX2,RPS14,CUX1,SIN3B,CBX5,FGF2,KDM6B,SKI,TRIM28,KHDRBS1,BTAF1,GATAD2A,ATXN1,TP63,MDM2,PA2G4,DEDD2,MEN1,SMAD4,ENO1,NFKB1,RBBP7,YWHAQ,SIN3A,NACC2,MLX,RNF2,SPEN,TBL1X,ZNF174,SAP30,SMAD7,TERF2,GABPA,NPM1,PPARD,PHF12,GTPBP4,PURB,CBFA2T2,HDAC1,NAB1,	4.51E-4
GO:0042326	negative regulation of phosphorylation	FKBP1A,PRKCA,PPP2R1A,ATXN7,MEN1,ATXN1,BAK1,SMAD7,PEBP1,DYNLL1,	7.58E-4
GO:0006413	translational initiation	EIF3I,EIF3K,BRF1,EIF2S3,EIF3C,EIF2B2,EIF3B,RPS3A,EIF3G,RPS5,	7.58E-4
GO:0031397	negative regulation of protein ubiquitination	PSMD11,PSMD2,PSMD3,PSMC3,UBB,PSMA4,PSMB6,GTPBP4,PSMA7,PSMF1,PSMB1,CDC20,SMAD7,	7.97E-4
GO:0008104	protein localization	TONSL,PDIA4,TAOK2,MFN2,WDR19,FGF2,SNX9,OPTN,SRPR,NUP210,RAB8A,BID,AAGAB,ATG16L1,CDC37,ARCN1,VANGL2,IPO4,NUP205,DHCR24,AURKB,AP2B1,ARF1,RFFL,MYO6,RAB36,GGA2,DOPEY2,YWHAQ,IPO7,G3BP2,XPO1,GSK3B,FLNA,NMD3,FLNB,STX3,AP3D1,IPO5,TNPO1,KPNA6,MYO1C,RAB11A,RRBP1,PDCD6IP,KDELR1,RPAIN,YIPF5,GABARAPL2,TOM1L1,COX18,SELENBP1,KIF20A,HSP90B1,SEC24A,NUP155,SNF8,ZFYVE20,TERF2,RPL11,KPNB1,NPM1,KPNA3,KPNA2,RANBP2,COPG,EZR,MACF1,MYH9,CLTC,ZFYVE16,TLN1,FAF1,	8.03E-4
GO:0006260	DNA replication	ORC6,CLSPN,MCM3,TERF2,POLI,CHAF1A,MCM7,HMGB1,POLE,CHEK1,RRM1,E4F1,DNAJA3,TYMP,RPAIN,CDC25A,ORC5,TFAM,RAD51,NFIB,RPA2,RBBP7,DTL,	1.00E-2
GO:0006605	protein targeting	YWHAQ,IPO7,XPO1,TAOK2,GSK3B,IPO5,TNPO1,MFN2,KPNA6,RPAIN,FGF2,OPTN,SRPR,RPL11,KPNB1,BID,KPNA3,CDC37,KPNA2,NUP205,IPO4,RANBP2,MACF1,ZFYVE16,MYO6,	1.02E-2
GO:0051352	negative regulation of ligase activity	PSMD11,PSMF1,PSMA7,PSMB1,PSMD2,PSMD3,CDC20,PSMC3,UBB,PSMA4,PSMB6,SMAD7,	1.17E-2
GO:0051444	negative regulation of ubiquitin-protein ligase activity	PSMD11,PSMF1,PSMA7,PSMB1,PSMD2,PSMD3,CDC20,PSMC3,UBB,PSMA4,PSMB6,SMAD7,	1.17E-2
GO:0034660	ncRNA metabolic process	RARS,ELAC2,EXOSC6,RPS14,RPS15,HSD17B10,SARS2,POP4,DDX56,AARS2,HEATR1,RPL11,IARS2,LARS,VARS,CARS,PA2G4,RPS28,RPS24,RRP9,DEDD2,QTRT1,FTSJ1,TRMT61A,EARS2,MARS,	1.19E-2
GO:0010563	negative regulation of phosphorus metabolic process	FKBP1A,PRKCA,PPP2R1A,ATXN7,MEN1,ATXN1,BAK1,SMAD7,PEBP1,DYNLL1,	1.23E-2
GO:0045936	negative regulation of phosphate metabolic process	FKBP1A,PRKCA,PPP2R1A,ATXN7,MEN1,ATXN1,BAK1,SMAD7,PEBP1,DYNLL1,	1.23E-2
GO:0016568	chromatin modification	BRCC3,SUPT5H,CBX2,EP300,RUVBL2,C20orf20,KAT2A,MSL3,RNF2,CBX6,ATXN7,KDM6B,ARID1A,RNF40,ARID1B,TERF2,JMJD6,KAT2B,SETD1B,WHSC1,DOT1L,MLL2,SETDB1,CARM1,HDAC1,MEN1,SMARCD2,KDM3B,RBBP7,	1.61E-2
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	MEF2C,CSDA,SIN3A,STAT3,MECP2,SUPT5H,CBX2,HMGB1,HES1,RPS14,CUX1,RNF2,TBL1X,KDM6B,SKI,ZNF174,SAP30,TRIM28,SMAD7,GABPA,TP63,MDM2,PPARD,HDAC1,MEN1,ENO1,NFKB1,RBBP7,	2.13E-2
GO:0010604	positive regulation of macromolecule metabolic process	MEF2C,SREBF2,SRF,BRCC3,STAT3,SUPT5H,HNRPLL,HES1,PRKCA,PSMA4,CDK1,CD276,PSMF1,IGF1R,FGF2,ATXN7,RAD51,TRIM28,MAML1,ARID1B,MAPK9,RORA,PSMD2,PSMD3,RXRB,ATXN1,TP63,PSMC3,MDM2,UBB,PSMB6,PSMA7,PSMB1,AXIN1,DDX5,MYO6,MEN1,SMAD4,CAMTA2,SERTAD3,NFKB1,EGLN2,PSMD11,PBX2,CBFB,ILF2,EP300,KLF2,BTRC,DNAJA3,TBL1X,BRF1,PLK1,ARID1A,NFIB,IRAK1,GATA5,SMAD7,CCND1,BMPR2,TERF2,ESR2,FKBP1A,CDC20,HDAC1,CCNB1,CCNE1,THBS1,ELF4,	2.33E-2
GO:0042274	ribosomal small subunit biogenesis	RPS24,NPM1,RPS14,RPS15,RPS28,	2.37E-2
GO:0048193	Golgi vesicle transport	DOPEY2,RAB8A,ERGIC2,ARCN1,DNM2,HSPA8,GOLGA3,ERGIC1,COPG,CUX1,ARRB1,ARF1,CLTC,GABARAPL2,OPTN,TRAPPC2,SEC24A,	2.74E-2
GO:0006916	anti-apoptosis	MEF2C,HSPA1B,NOTCH2,NPM1,HMGB1,GSK3B,TP63,ESR2,UBB,GLO1,CDK1,IGF1R,DHCR24,GSTP1,TPT1,ARHGDIA,HDAC1,BFAR,NFKB1,IRAK1,HSP90B1,HIPK3,THBS1,	2.84E-2
GO:0050658	RNA transport	NUP210,G3BP2,XPO1,KHSRP,NPM1,UPF2,DDX39A,PABPN1,MYO1C,NUP205,RANBP2,HNRNPA2B1,XPOT,NUP155,	2.95E-2
GO:0050657	nucleic acid transport	NUP210,G3BP2,XPO1,KHSRP,NPM1,UPF2,DDX39A,PABPN1,MYO1C,NUP205,RANBP2,HNRNPA2B1,XPOT,NUP155,	2.95E-2
GO:0051236	establishment of RNA localization	NUP210,G3BP2,XPO1,KHSRP,NPM1,UPF2,DDX39A,PABPN1,MYO1C,NUP205,RANBP2,HNRNPA2B1,XPOT,NUP155,	2.95E-2
GO:0006606	protein import into nucleus	IPO7,KPNB1,XPO1,KPNA3,KPNA2,IPO5,TNPO1,KPNA6,IPO4,NUP205,RANBP2,RPAIN,FGF2,	3.00E-2
GO:0051436	negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle	PSMD11,PSMF1,PSMA7,PSMB1,PSMD2,PSMD3,CDC20,PSMC3,UBB,PSMA4,PSMB6,	3.18E-2
GO:0007051	spindle organization	SMC1A,ZWINT,SMC3,MYH9,TUBB,RCC1,HAUS1,PRC1,DYNC1H1,	3.23E-2
GO:0033365	protein localization in organelle	SRPR,IPO7,BID,KPNB1,XPO1,KPNA3,KPNA2,IPO5,TNPO1,MFN2,KPNA6,IPO4,NUP205,RANBP2,MACF1,RPAIN,FGF2,OPTN,	3.40E-2
GO:0051170	nuclear import	IPO7,KPNB1,XPO1,KPNA3,KPNA2,IPO5,TNPO1,KPNA6,IPO4,NUP205,RANBP2,RPAIN,FGF2,	3.64E-2
GO:0000226	microtubule cytoskeleton organization	SMC1A,ZWINT,TUBGCP2,STMN3,NPM1,RCC1,PPP4C,DYNC1H1,TTL,MACF1,KIF2C,SMC3,MYH9,NEK2,TUBB,HAUS1,PRC1,MAP1B,	3.65E-2
GO:0006418	tRNA aminoacylation for protein translation	AARS2,RARS,SARS2,IARS2,LARS,VARS,CARS,EARS2,MARS,	3.72E-2
GO:0043038	amino acid activation	AARS2,RARS,SARS2,IARS2,LARS,VARS,CARS,EARS2,MARS,	3.72E-2
GO:0043039	tRNA aminoacylation	AARS2,RARS,SARS2,IARS2,LARS,VARS,CARS,EARS2,MARS,	3.72E-2
GO:0045184	establishment of protein localization	PDIA4,TAOK2,MFN2,WDR19,FGF2,SNX9,OPTN,SRPR,NUP210,RAB8A,BID,AAGAB,ATG16L1,CDC37,ARCN1,IPO4,NUP205,AP2B1,ARF1,RFFL,MYO6,RAB36,GGA2,DOPEY2,YWHAQ,IPO7,XPO1,GSK3B,FLNA,NMD3,STX3,AP3D1,IPO5,TNPO1,KPNA6,MYO1C,RAB11A,RRBP1,PDCD6IP,KDELR1,RPAIN,YIPF5,GABARAPL2,TOM1L1,SELENBP1,KIF20A,HSP90B1,NUP155,SEC24A,SNF8,ZFYVE20,RPL11,KPNB1,KPNA3,NPM1,KPNA2,RANBP2,COPG,MACF1,MYH9,CLTC,ZFYVE16,	3.85E-2
GO:0006403	RNA localization	NUP210,G3BP2,XPO1,KHSRP,NPM1,UPF2,DDX39A,PABPN1,MYO1C,NUP205,RANBP2,HNRNPA2B1,XPOT,NUP155,	3.86E-2
GO:0043484	regulation of RNA splicing	JMJD6,HNRPLL,NPM1,HNRNPF,SNRNP70,MBNL1,	4.22E-2
GO:0007018	microtubule-based movement	KIF18B,TUBB2B,KIFC1,DYNC1H1,TUBB4B,MACF1,UCHL1,TUBB3,KIF2C,TUBB,KIF1A,TUBA1C,KIF20A,KLC2,RHOT2,	4.31E-2
GO:0006607	NLS-bearing substrate import into nucleus	KPNB1,KPNA3,KPNA2,IPO5,KPNA6,	4.69E-2
GO:0015031	protein transport	PDIA4,TAOK2,MFN2,WDR19,FGF2,SNX9,OPTN,SRPR,NUP210,RAB8A,BID,AAGAB,ATG16L1,CDC37,ARCN1,NUP205,IPO4,AP2B1,ARF1,RFFL,MYO6,RAB36,GGA2,DOPEY2,YWHAQ,IPO7,XPO1,GSK3B,NMD3,STX3,AP3D1,IPO5,TNPO1,KPNA6,MYO1C,RAB11A,RRBP1,PDCD6IP,KDELR1,RPAIN,YIPF5,GABARAPL2,TOM1L1,SELENBP1,KIF20A,HSP90B1,NUP155,SEC24A,SNF8,ZFYVE20,RPL11,KPNB1,KPNA3,NPM1,KPNA2,RANBP2,COPG,MACF1,MYH9,CLTC,ZFYVE16,	4.71E-2
GO:0051329	interphase of mitotic cell cycle	CCND1,KPNA2,POLE,CHEK1,CUL5,RCC1,PPP6C,MDM2,DNM2,CDKN3,CDC25A,CCNB1,CCNE1,KHDRBS1,	4.98E-2
GO:0006333	chromatin assembly or disassembly	CHAF1A,NPM1,CBX2,ARID4B,HIST1H1E,SHPRH,CBX5,MSL3,HIST1H3D,HIST1H2AE,HIST1H2AH,CBX6,HIST1H4C,HIST2H2AA3,HIST1H2AM,HIST1H2AB,HIST1H2AC,H1FX,	5.03E-2
GO:0006457	protein folding	FKBPL,RUVBL2,PPIB,FKBP8,HSPA8,DNAJA3,HSP90AB1,FKBP4,PPIL1,PFDN6,HSPBP1,PFDN2,RANBP2,FKBP1A,VBP1,DNAJB12,CCT7,TRAP1,HSP90B1,DNAJC21,	5.04E-2
GO:0034504	protein localization in nucleus	IPO7,KPNB1,XPO1,KPNA3,KPNA2,IPO5,TNPO1,KPNA6,IPO4,NUP205,RANBP2,RPAIN,FGF2,	6.24E-2
GO:0051325	interphase	CCND1,KPNA2,POLE,CHEK1,CUL5,RCC1,PPP6C,MDM2,DNM2,CDKN3,CDC25A,CCNB1,CCNE1,KHDRBS1,	6.36E-2
GO:0043009	chordate embryonic development	PTK7,SRF,CSDA,BTF3,EP300,HES1,IFT172,FKBP8,MFN2,KAT2A,NLE1,NKX3-1,MAFG,NDST1,RIC8A,TGFBR2,BCL2L11,MBNL1,HOXA5,GABPA,TERF2,PSMC3,VANGL2,MLL2,PLCG1,MYH9,ATM,MEN1,CELSR1,PFN1,CDH1,	6.66E-2
GO:0032507	maintenance of protein location in cell	EZR,TONSL,KDELR1,G3BP2,TLN1,FLNA,FLNB,FAF1,	7.24E-2
GO:0016072	rRNA metabolic process	DDX56,HEATR1,RPL11,RPS14,EXOSC6,RPS15,PA2G4,RPS28,RPS24,RRP9,DEDD2,FTSJ1,POP4,	7.38E-2
GO:0009792	embryonic development ending in birth or egg hatching	PTK7,SRF,CSDA,BTF3,EP300,HES1,IFT172,FKBP8,MFN2,KAT2A,NLE1,NKX3-1,MAFG,NDST1,RIC8A,TGFBR2,BCL2L11,MBNL1,HOXA5,GABPA,TERF2,PSMC3,VANGL2,MLL2,PLCG1,MYH9,ATM,MEN1,CELSR1,PFN1,CDH1,	7.56E-2
GO:0006351	transcription, DNA-dependent	BTF3,NFE2L1,GATA3,CBFB,SUPT5H,POLR2I,CDK9,KAT2A,GTF3C1,MSL3,GTF3C2,BRF1,TFAM,TCOF1,TCEB2,POLRMT,HCFC1,POLR2L,BMPR2,GABPA,TMF1,CD3EAP,SCAF8,MED16,POLR3A,MYEF2,NFKB1,ADRM1,	7.56E-2
GO:0001933	negative regulation of protein amino acid phosphorylation	FKBP1A,PRKCA,PPP2R1A,MEN1,BAK1,SMAD7,PEBP1,	7.96E-2
GO:0042176	regulation of protein catabolic process	PSMD2,PSMD3,XPO1,FLNA,MDM2,FAF1,HSP90AB1,EGLN2,SMAD7,	8.00E-2
GO:0030705	cytoskeleton-dependent intracellular transport	MYH2,MACF1,UCHL1,MYL6,MYH9,MYO6,KIF1A,KLC2,RHOT2,	8.00E-2
GO:0007052	mitotic spindle organization	SMC1A,SMC3,RCC1,PRC1,DYNC1H1,	8.20E-2
GO:0032774	RNA biosynthetic process	BTF3,NFE2L1,GATA3,CBFB,SUPT5H,POLR2I,CDK9,KAT2A,GTF3C1,MSL3,GTF3C2,BRF1,TFAM,TCOF1,TCEB2,POLRMT,HCFC1,POLR2L,BMPR2,GABPA,TMF1,CD3EAP,SCAF8,MED16,POLR3A,MYEF2,NFKB1,ADRM1,	8.99E-2
GO:0042257	ribosomal subunit assembly	RPL24,RPS14,RPS15,	9.10E-2

KEGG pathways and Gene Ontology terms enriched for the interacted genes of ncRNA from RAID and miRTarBase.

disease name	related genes	p-value