| KEGG pathways enriched for interacted genes |
| pathway name | pathway description | target genes enrich in pathway | p-value |
|
|
hsa04140
|
Regulation of autophagy |
BECN1,ATG5, |
2.72E-1 |
|
hsa05214
|
Glioma |
PTEN,CDKN1A, |
4.86E-1 |
|
hsa04115
|
p53 signaling pathway |
PTEN,CDKN1A, |
5.24E-1 |
|
hsa05218
|
Melanoma |
PTEN,CDKN1A, |
5.47E-1 |
|
hsa05215
|
Prostate cancer |
PTEN,CDKN1A, |
6.82E-1 |
|
|
|
|
| Gene ontology terms enriched for interacted genes |
| GO terms | GO terms description | target genes enrich in GO term | p-value |
|
|
GO:0006914
|
autophagy |
ATG10,ATG16L1,BECN1,ATG5, |
1.69E-6 |
|
GO:0009991
|
response to extracellular stimulus |
PTEN,ATG16L1,BECN1,CDKN1A,ATG5, |
8.04E-6 |
|
GO:0031668
|
cellular response to extracellular stimulus |
ATG16L1,BECN1,CDKN1A,ATG5, |
8.31E-6 |
|
GO:0000045
|
autophagic vacuole formation |
ATG16L1,BECN1,ATG5, |
2.58E-5 |
|
GO:0016236
|
macroautophagy |
ATG16L1,BECN1,ATG5, |
3.56E-5 |
|
|
|
GO:0009267
|
cellular response to starvation |
ATG16L1,BECN1,ATG5, |
1.93E-4 |
|
GO:0031667
|
response to nutrient levels |
PTEN,ATG16L1,BECN1,ATG5, |
2.39E-4 |
|
GO:0007033
|
vacuole organization |
ATG16L1,BECN1,ATG5, |
3.02E-4 |
|
GO:0033554
|
cellular response to stress |
ATG10,ATG16L1,BECN1,CDKN1A,ATG5, |
3.22E-4 |
|
GO:0042594
|
response to starvation |
ATG16L1,BECN1,ATG5, |
3.34E-4 |
|
GO:0031669
|
cellular response to nutrient levels |
ATG16L1,BECN1,ATG5, |
3.66E-4 |
|
GO:0043066
|
negative regulation of apoptosis |
PTEN,BECN1,CDKN1A,ATG5, |
1.32E-2 |
|
GO:0043069
|
negative regulation of programmed cell death |
PTEN,BECN1,CDKN1A,ATG5, |
1.38E-2 |
|
GO:0060548
|
negative regulation of cell death |
PTEN,BECN1,CDKN1A,ATG5, |
1.39E-2 |
|
GO:0046685
|
response to arsenic |
PTEN,CDKN1A, |
6.63E-2 |
|
GO:0010608
|
posttranscriptional regulation of gene expression |
PTEN,DICER1,ELAVL1, |
8.10E-2 |
|
GO:0048514
|
blood vessel morphogenesis |
PTEN,DICER1,ATG5, |
8.10E-2 |
|
GO:0042493
|
response to drug |
PTEN,CDKN1A,ATG5, |
8.48E-2 |
|
|
|
|
|
|
|