ncRNADetailInformation

Detail Information
Functional analysis

miRNA name

pre-miRNA

family

pre-miRNA Sequence

mature-miRNA

mature sequence

pre-miRNA description

miR-451

MI0001729	MIPF0000148	CUUGGGAAUGGCAAGGAAACCGUUACCAUUACUGAGUUUAGUAAUGGUAAUGGUUCUCUUGCUAUACCCAGA	MIMAT0001631 hsa-miR-451a	AAACCGUUACCAUUACUGAGUU
MI0017360	MIPF0000148	UGGGUAUAGCAAGAGAACCAUUACCAUUACUAAACUCAGUAAUGGUAACGGUUUCCUUGCCAUUCCCA	MIMAT0019840 hsa-miR-451b	UAGCAAGAGAACCAUUACCAUU
MI0001729	MIPF0000148	CUUGGGAAUGGCAAGGAAACCGUUACCAUUACUGAGUUUAGUAAUGGUAAUGGUUCUCUUGCUAUACCCAGA	MIMAT0001631 hsa-miR-451a	AAACCGUUACCAUUACUGAGUU
MI0017360	MIPF0000148	UGGGUAUAGCAAGAGAACCAUUACCAUUACUAAACUCAGUAAUGGUAACGGUUUCCUUGCCAUUCCCA	MIMAT0019840 hsa-miR-451b	UAGCAAGAGAACCAUUACCAUU
MI0017360	MIPF0000148	UGGGUAUAGCAAGAGAACCAUUACCAUUACUAAACUCAGUAAUGGUAACGGUUUCCUUGCCAUUCCCA	MIMAT0019840 hsa-miR-451b	UAGCAAGAGAACCAUUACCAUU
MI0001729	MIPF0000148	CUUGGGAAUGGCAAGGAAACCGUUACCAUUACUGAGUUUAGUAAUGGUAAUGGUUCUCUUGCUAUACCCAGA	MIMAT0001631 hsa-miR-451a	AAACCGUUACCAUUACUGAGUU
MI0001729	MIPF0000148	CUUGGGAAUGGCAAGGAAACCGUUACCAUUACUGAGUUUAGUAAUGGUAAUGGUUCUCUUGCUAUACCCAGA	MIMAT0001631 hsa-miR-451a	AAACCGUUACCAUUACUGAGUU
MI0017360	MIPF0000148	UGGGUAUAGCAAGAGAACCAUUACCAUUACUAAACUCAGUAAUGGUAACGGUUUCCUUGCCAUUCCCA	MIMAT0019840 hsa-miR-451b	UAGCAAGAGAACCAUUACCAUU
MI0001729	MIPF0000148	CUUGGGAAUGGCAAGGAAACCGUUACCAUUACUGAGUUUAGUAAUGGUAAUGGUUCUCUUGCUAUACCCAGA	MIMAT0001631 hsa-miR-451a	AAACCGUUACCAUUACUGAGUU
MI0017360	MIPF0000148	UGGGUAUAGCAAGAGAACCAUUACCAUUACUAAACUCAGUAAUGGUAACGGUUUCCUUGCCAUUCCCA	MIMAT0019840 hsa-miR-451b	UAGCAAGAGAACCAUUACCAUU
MI0017360	MIPF0000148	UGGGUAUAGCAAGAGAACCAUUACCAUUACUAAACUCAGUAAUGGUAACGGUUUCCUUGCCAUUCCCA	MIMAT0019840 hsa-miR-451b	UAGCAAGAGAACCAUUACCAUU
MI0001729	MIPF0000148	CUUGGGAAUGGCAAGGAAACCGUUACCAUUACUGAGUUUAGUAAUGGUAAUGGUUCUCUUGCUAUACCCAGA	MIMAT0001631 hsa-miR-451a	AAACCGUUACCAUUACUGAGUU
MI0001729	MIPF0000148	CUUGGGAAUGGCAAGGAAACCGUUACCAUUACUGAGUUUAGUAAUGGUAAUGGUUCUCUUGCUAUACCCAGA	MIMAT0001631 hsa-miR-451a	AAACCGUUACCAUUACUGAGUU
MI0017360	MIPF0000148	UGGGUAUAGCAAGAGAACCAUUACCAUUACUAAACUCAGUAAUGGUAACGGUUUCCUUGCCAUUCCCA	MIMAT0019840 hsa-miR-451b	UAGCAAGAGAACCAUUACCAUU
MI0017360	MIPF0000148	UGGGUAUAGCAAGAGAACCAUUACCAUUACUAAACUCAGUAAUGGUAACGGUUUCCUUGCCAUUCCCA	MIMAT0019840 hsa-miR-451b	UAGCAAGAGAACCAUUACCAUU
MI0001729	MIPF0000148	CUUGGGAAUGGCAAGGAAACCGUUACCAUUACUGAGUUUAGUAAUGGUAAUGGUUCUCUUGCUAUACCCAGA	MIMAT0001631 hsa-miR-451a	AAACCGUUACCAUUACUGAGUU
MI0001729	MIPF0000148	CUUGGGAAUGGCAAGGAAACCGUUACCAUUACUGAGUUUAGUAAUGGUAAUGGUUCUCUUGCUAUACCCAGA	MIMAT0001631 hsa-miR-451a	AAACCGUUACCAUUACUGAGUU
MI0017360	MIPF0000148	UGGGUAUAGCAAGAGAACCAUUACCAUUACUAAACUCAGUAAUGGUAACGGUUUCCUUGCCAUUCCCA	MIMAT0019840 hsa-miR-451b	UAGCAAGAGAACCAUUACCAUU
MI0017360	MIPF0000148	UGGGUAUAGCAAGAGAACCAUUACCAUUACUAAACUCAGUAAUGGUAACGGUUUCCUUGCCAUUCCCA	MIMAT0019840 hsa-miR-451b	UAGCAAGAGAACCAUUACCAUU
MI0001729	MIPF0000148	CUUGGGAAUGGCAAGGAAACCGUUACCAUUACUGAGUUUAGUAAUGGUAAUGGUUCUCUUGCUAUACCCAGA	MIMAT0001631 hsa-miR-451a	AAACCGUUACCAUUACUGAGUU
MI0001729	MIPF0000148	CUUGGGAAUGGCAAGGAAACCGUUACCAUUACUGAGUUUAGUAAUGGUAAUGGUUCUCUUGCUAUACCCAGA	MIMAT0001631 hsa-miR-451a	AAACCGUUACCAUUACUGAGUU
MI0017360	MIPF0000148	UGGGUAUAGCAAGAGAACCAUUACCAUUACUAAACUCAGUAAUGGUAACGGUUUCCUUGCCAUUCCCA	MIMAT0019840 hsa-miR-451b	UAGCAAGAGAACCAUUACCAUU
MI0001729	MIPF0000148	CUUGGGAAUGGCAAGGAAACCGUUACCAUUACUGAGUUUAGUAAUGGUAAUGGUUCUCUUGCUAUACCCAGA	MIMAT0001631 hsa-miR-451a	AAACCGUUACCAUUACUGAGUU
MI0017360	MIPF0000148	UGGGUAUAGCAAGAGAACCAUUACCAUUACUAAACUCAGUAAUGGUAACGGUUUCCUUGCCAUUCCCA	MIMAT0019840 hsa-miR-451b	UAGCAAGAGAACCAUUACCAUU
MI0017360	MIPF0000148	UGGGUAUAGCAAGAGAACCAUUACCAUUACUAAACUCAGUAAUGGUAACGGUUUCCUUGCCAUUCCCA	MIMAT0019840 hsa-miR-451b	UAGCAAGAGAACCAUUACCAUU
MI0001729	MIPF0000148	CUUGGGAAUGGCAAGGAAACCGUUACCAUUACUGAGUUUAGUAAUGGUAAUGGUUCUCUUGCUAUACCCAGA	MIMAT0001631 hsa-miR-451a	AAACCGUUACCAUUACUGAGUU
MI0017360	MIPF0000148	UGGGUAUAGCAAGAGAACCAUUACCAUUACUAAACUCAGUAAUGGUAACGGUUUCCUUGCCAUUCCCA	MIMAT0019840 hsa-miR-451b	UAGCAAGAGAACCAUUACCAUU
MI0001729	MIPF0000148	CUUGGGAAUGGCAAGGAAACCGUUACCAUUACUGAGUUUAGUAAUGGUAAUGGUUCUCUUGCUAUACCCAGA	MIMAT0001631 hsa-miR-451a	AAACCGUUACCAUUACUGAGUU
MI0001729	MIPF0000148	CUUGGGAAUGGCAAGGAAACCGUUACCAUUACUGAGUUUAGUAAUGGUAAUGGUUCUCUUGCUAUACCCAGA	MIMAT0001631 hsa-miR-451a	AAACCGUUACCAUUACUGAGUU
MI0017360	MIPF0000148	UGGGUAUAGCAAGAGAACCAUUACCAUUACUAAACUCAGUAAUGGUAACGGUUUCCUUGCCAUUCCCA	MIMAT0019840 hsa-miR-451b	UAGCAAGAGAACCAUUACCAUU
MI0001729	MIPF0000148	CUUGGGAAUGGCAAGGAAACCGUUACCAUUACUGAGUUUAGUAAUGGUAAUGGUUCUCUUGCUAUACCCAGA	MIMAT0001631 hsa-miR-451a	AAACCGUUACCAUUACUGAGUU
MI0017360	MIPF0000148	UGGGUAUAGCAAGAGAACCAUUACCAUUACUAAACUCAGUAAUGGUAACGGUUUCCUUGCCAUUCCCA	MIMAT0019840 hsa-miR-451b	UAGCAAGAGAACCAUUACCAUU
MI0001729	MIPF0000148	CUUGGGAAUGGCAAGGAAACCGUUACCAUUACUGAGUUUAGUAAUGGUAAUGGUUCUCUUGCUAUACCCAGA	MIMAT0001631 hsa-miR-451a	AAACCGUUACCAUUACUGAGUU
MI0017360	MIPF0000148	UGGGUAUAGCAAGAGAACCAUUACCAUUACUAAACUCAGUAAUGGUAACGGUUUCCUUGCCAUUCCCA	MIMAT0019840 hsa-miR-451b	UAGCAAGAGAACCAUUACCAUU
MI0001729	MIPF0000148	CUUGGGAAUGGCAAGGAAACCGUUACCAUUACUGAGUUUAGUAAUGGUAAUGGUUCUCUUGCUAUACCCAGA	MIMAT0001631 hsa-miR-451a	AAACCGUUACCAUUACUGAGUU
MI0017360	MIPF0000148	UGGGUAUAGCAAGAGAACCAUUACCAUUACUAAACUCAGUAAUGGUAACGGUUUCCUUGCCAUUCCCA	MIMAT0019840 hsa-miR-451b	UAGCAAGAGAACCAUUACCAUU
MI0001729	MIPF0000148	CUUGGGAAUGGCAAGGAAACCGUUACCAUUACUGAGUUUAGUAAUGGUAAUGGUUCUCUUGCUAUACCCAGA	MIMAT0001631 hsa-miR-451a	AAACCGUUACCAUUACUGAGUU
MI0017360	MIPF0000148	UGGGUAUAGCAAGAGAACCAUUACCAUUACUAAACUCAGUAAUGGUAACGGUUUCCUUGCCAUUCCCA	MIMAT0019840 hsa-miR-451b	UAGCAAGAGAACCAUUACCAUU
MI0001729	MIPF0000148	CUUGGGAAUGGCAAGGAAACCGUUACCAUUACUGAGUUUAGUAAUGGUAAUGGUUCUCUUGCUAUACCCAGA	MIMAT0001631 hsa-miR-451a	AAACCGUUACCAUUACUGAGUU
MI0017360	MIPF0000148	UGGGUAUAGCAAGAGAACCAUUACCAUUACUAAACUCAGUAAUGGUAACGGUUUCCUUGCCAUUCCCA	MIMAT0019840 hsa-miR-451b	UAGCAAGAGAACCAUUACCAUU
MI0001729	MIPF0000148	CUUGGGAAUGGCAAGGAAACCGUUACCAUUACUGAGUUUAGUAAUGGUAAUGGUUCUCUUGCUAUACCCAGA	MIMAT0001631 hsa-miR-451a	AAACCGUUACCAUUACUGAGUU
MI0017360	MIPF0000148	UGGGUAUAGCAAGAGAACCAUUACCAUUACUAAACUCAGUAAUGGUAACGGUUUCCUUGCCAUUCCCA	MIMAT0019840 hsa-miR-451b	UAGCAAGAGAACCAUUACCAUU
MI0001729	MIPF0000148	CUUGGGAAUGGCAAGGAAACCGUUACCAUUACUGAGUUUAGUAAUGGUAAUGGUUCUCUUGCUAUACCCAGA	MIMAT0001631 hsa-miR-451a	AAACCGUUACCAUUACUGAGUU
MI0017360	MIPF0000148	UGGGUAUAGCAAGAGAACCAUUACCAUUACUAAACUCAGUAAUGGUAACGGUUUCCUUGCCAUUCCCA	MIMAT0019840 hsa-miR-451b	UAGCAAGAGAACCAUUACCAUU
MI0017360	MIPF0000148	UGGGUAUAGCAAGAGAACCAUUACCAUUACUAAACUCAGUAAUGGUAACGGUUUCCUUGCCAUUCCCA	MIMAT0019840 hsa-miR-451b	UAGCAAGAGAACCAUUACCAUU
MI0001729	MIPF0000148	CUUGGGAAUGGCAAGGAAACCGUUACCAUUACUGAGUUUAGUAAUGGUAAUGGUUCUCUUGCUAUACCCAGA	MIMAT0001631 hsa-miR-451a	AAACCGUUACCAUUACUGAGUU
MI0017360	MIPF0000148	UGGGUAUAGCAAGAGAACCAUUACCAUUACUAAACUCAGUAAUGGUAACGGUUUCCUUGCCAUUCCCA	MIMAT0019840 hsa-miR-451b	UAGCAAGAGAACCAUUACCAUU
MI0001729	MIPF0000148	CUUGGGAAUGGCAAGGAAACCGUUACCAUUACUGAGUUUAGUAAUGGUAAUGGUUCUCUUGCUAUACCCAGA	MIMAT0001631 hsa-miR-451a	AAACCGUUACCAUUACUGAGUU
MI0001729	MIPF0000148	CUUGGGAAUGGCAAGGAAACCGUUACCAUUACUGAGUUUAGUAAUGGUAAUGGUUCUCUUGCUAUACCCAGA	MIMAT0001631 hsa-miR-451a	AAACCGUUACCAUUACUGAGUU
MI0017360	MIPF0000148	UGGGUAUAGCAAGAGAACCAUUACCAUUACUAAACUCAGUAAUGGUAACGGUUUCCUUGCCAUUCCCA	MIMAT0019840 hsa-miR-451b	UAGCAAGAGAACCAUUACCAUU
MI0017360	MIPF0000148	UGGGUAUAGCAAGAGAACCAUUACCAUUACUAAACUCAGUAAUGGUAACGGUUUCCUUGCCAUUCCCA	MIMAT0019840 hsa-miR-451b	UAGCAAGAGAACCAUUACCAUU
MI0001729	MIPF0000148	CUUGGGAAUGGCAAGGAAACCGUUACCAUUACUGAGUUUAGUAAUGGUAAUGGUUCUCUUGCUAUACCCAGA	MIMAT0001631 hsa-miR-451a	AAACCGUUACCAUUACUGAGUU
MI0017360	MIPF0000148	UGGGUAUAGCAAGAGAACCAUUACCAUUACUAAACUCAGUAAUGGUAACGGUUUCCUUGCCAUUCCCA	MIMAT0019840 hsa-miR-451b	UAGCAAGAGAACCAUUACCAUU
MI0001729	MIPF0000148	CUUGGGAAUGGCAAGGAAACCGUUACCAUUACUGAGUUUAGUAAUGGUAAUGGUUCUCUUGCUAUACCCAGA	MIMAT0001631 hsa-miR-451a	AAACCGUUACCAUUACUGAGUU

link to database

TargetScanS 6.2 | MicroCosm | microRNA.org | miRNAMap 2.0

Interacted genes from RAID,miRTarBase

AKT1,PIK3CA,PRKAA1,MYC,MMP2,ABCB1,CAB39,STK11,RAB14,TMED7,MMP9,RAB5A,BCL2,ARPP19,MIF
more » AKT1,PIK3CA,PRKAA1,MYC,MMP2,ABCB1,CAB39,STK11,RAB14,TMED7,MMP9,RAB5A,BCL2,ARPP19,MIF

KEGG pathways enriched for interacted genes

pathway name

pathway description

target genes enrich in pathway

p-value

hsa04150	mTOR signaling pathway	PIK3CA,CAB39,PRKAA1,STK11,AKT1,	6.49E-6
hsa05200	Pathways in cancer	PIK3CA,MMP2,BCL2,MMP9,AKT1,MYC,	9.05E-4
hsa05222	Small cell lung cancer	PIK3CA,BCL2,AKT1,MYC,	1.10E-2
hsa05210	Colorectal cancer	PIK3CA,BCL2,AKT1,MYC,	1.10E-2
hsa05219	Bladder cancer	MMP2,MMP9,MYC,	4.90E-2

hsa05213	Endometrial cancer	PIK3CA,AKT1,MYC,	7.44E-2
hsa05221	Acute myeloid leukemia	PIK3CA,AKT1,MYC,	9.20E-2
hsa04920	Adipocytokine signaling pathway	PRKAA1,STK11,AKT1,	1.21E-1
hsa05220	Chronic myeloid leukemia	PIK3CA,AKT1,MYC,	1.50E-1
hsa04210	Apoptosis	PIK3CA,BCL2,AKT1,	1.99E-1
hsa04012	ErbB signaling pathway	PIK3CA,AKT1,MYC,	1.99E-1
hsa05215	Prostate cancer	PIK3CA,BCL2,AKT1,	2.08E-1
hsa04620	Toll-like receptor signaling pathway	PIK3CA,TMED7,AKT1,	2.64E-1
hsa04670	Leukocyte transendothelial migration	PIK3CA,MMP2,MMP9,	3.52E-1
hsa04722	Neurotrophin signaling pathway	PIK3CA,BCL2,AKT1,	3.86E-1
hsa04910	Insulin signaling pathway	PIK3CA,PRKAA1,AKT1,	4.50E-1
hsa04630	Jak-STAT signaling pathway	PIK3CA,AKT1,MYC,	5.77E-1
hsa04510	Focal adhesion	PIK3CA,BCL2,AKT1,	9.11E-1

Gene ontology terms enriched for interacted genes

GO terms

GO terms description

target genes enrich in GO term

p-value

GO:0010565	regulation of cellular ketone metabolic process	CAB39,PRKAA1,ARPP19,STK11,AKT1,	3.73E-7
GO:0046320	regulation of fatty acid oxidation	CAB39,PRKAA1,STK11,AKT1,	3.55E-6
GO:0019217	regulation of fatty acid metabolic process	CAB39,PRKAA1,STK11,AKT1,	1.97E-5
GO:0019216	regulation of lipid metabolic process	CAB39,PRKAA1,STK11,AKT1,	2.33E-4
GO:0008633	activation of pro-apoptotic gene products	BCL2,AKT1,MYC,	2.61E-4

GO:0043066	negative regulation of apoptosis	MIF,PIK3CA,BCL2,AKT1,MYC,	5.00E-4
GO:0008637	apoptotic mitochondrial changes	BCL2,AKT1,MYC,	5.23E-4
GO:0043069	negative regulation of programmed cell death	MIF,PIK3CA,BCL2,AKT1,MYC,	5.27E-4
GO:0060548	negative regulation of cell death	MIF,PIK3CA,BCL2,AKT1,MYC,	5.33E-4
GO:0006006	glucose metabolic process	PIK3CA,PRKAA1,AKT1,MYC,	5.84E-4
GO:0019318	hexose metabolic process	PIK3CA,PRKAA1,AKT1,MYC,	1.12E-2
GO:0042981	regulation of apoptosis	MIF,PIK3CA,BCL2,MMP9,AKT1,MYC,	1.33E-2
GO:0006916	anti-apoptosis	PIK3CA,BCL2,AKT1,MYC,	1.38E-2
GO:0043067	regulation of programmed cell death	MIF,PIK3CA,BCL2,MMP9,AKT1,MYC,	1.39E-2
GO:0010941	regulation of cell death	MIF,PIK3CA,BCL2,MMP9,AKT1,MYC,	1.41E-2
GO:0005996	monosaccharide metabolic process	PIK3CA,PRKAA1,AKT1,MYC,	1.71E-2
GO:0040014	regulation of multicellular organism growth	PIK3CA,BCL2,AKT1,	2.02E-2
GO:0001501	skeletal system development	MMP2,BCL2,MMP9,MYC,	4.78E-2
GO:0006468	protein amino acid phosphorylation	PIK3CA,BCL2,PRKAA1,STK11,AKT1,	5.17E-2
GO:0007243	protein kinase cascade	PIK3CA,TMED7,PRKAA1,AKT1,	7.22E-2
GO:0007242	intracellular signaling cascade	PIK3CA,TMED7,PRKAA1,RAB5A,AKT1,RAB14,	9.30E-2
GO:0001666	response to hypoxia	MMP2,BCL2,PRKAA1,	9.39E-2
GO:0016310	phosphorylation	PIK3CA,BCL2,PRKAA1,STK11,AKT1,	9.80E-2
GO:0043491	protein kinase B signaling cascade	PIK3CA,AKT1,	9.93E-2
GO:0032880	regulation of protein localization	BCL2,AKT1,RAB14,	9.94E-2
GO:0007005	mitochondrion organization	BCL2,AKT1,MYC,	9.94E-2

KEGG pathways and Gene Ontology terms enriched for the interacted genes of ncRNA from RAID and miRTarBase.

disease name	related genes	p-value