ncRNADetailInformation

Detail Information
Functional analysis

miRNA name

pre-miRNA

family

pre-miRNA Sequence

mature-miRNA

mature sequence

pre-miRNA description

miR-30c

MI0000736	MIPF0000005	ACCAUGCUGUAGUGUGUGUAAACAUCCUACACUCUCAGCUGUGAGCUCAAGGUGGCUGGGAGAGGGUUGUUUACUCCUUCUGCCAUGGA	MIMAT0000244 hsa-miR-30c-5p	UGUAAACAUCCUACACUCUCAGC	miR-30c was cloned from mouse heart and brain tissues by Lagos-Quintana etal. . Two human hairpin precursor sequences are predicted based onhomology with the mouse sequences, on chromosomes 1 (MIR:MI0000736) and 6(MIR:MI0000254) . Expression of miR-30c was later validated in humanHL-60 leukemia cells .
MI0000254	MIPF0000005	AGAUACUGUAAACAUCCUACACUCUCAGCUGUGGAAAGUAAGAAAGCUGGGAGAAGGCUGUUUACUCUUUCU	MIMAT0004550 hsa-miR-30c-2-3p	CUGGGAGAAGGCUGUUUACUCU	miR-30c was cloned from mouse heart and brain tissues by Lagos-Quintana etal. . Two human hairpin precursor sequences are predicted based onhomology with the mouse sequences, on chromosomes 1 (MIR:MI0000736) and 6(MIR:MI0000254) . Expression of miR-30c was later independentlyverified in human HL-60 leukemia cells .
MI0000736	MIPF0000005	ACCAUGCUGUAGUGUGUGUAAACAUCCUACACUCUCAGCUGUGAGCUCAAGGUGGCUGGGAGAGGGUUGUUUACUCCUUCUGCCAUGGA	MIMAT0004674 hsa-miR-30c-1-3p	CUGGGAGAGGGUUGUUUACUCC	miR-30c was cloned from mouse heart and brain tissues by Lagos-Quintana etal. . Two human hairpin precursor sequences are predicted based onhomology with the mouse sequences, on chromosomes 1 (MIR:MI0000736) and 6(MIR:MI0000254) . Expression of miR-30c was later validated in humanHL-60 leukemia cells .
MI0000736	MIPF0000005	ACCAUGCUGUAGUGUGUGUAAACAUCCUACACUCUCAGCUGUGAGCUCAAGGUGGCUGGGAGAGGGUUGUUUACUCCUUCUGCCAUGGA	MIMAT0000244 hsa-miR-30c-5p	UGUAAACAUCCUACACUCUCAGC	miR-30c was cloned from mouse heart and brain tissues by Lagos-Quintana etal. . Two human hairpin precursor sequences are predicted based onhomology with the mouse sequences, on chromosomes 1 (MIR:MI0000736) and 6(MIR:MI0000254) . Expression of miR-30c was later validated in humanHL-60 leukemia cells .
MI0000254	MIPF0000005	AGAUACUGUAAACAUCCUACACUCUCAGCUGUGGAAAGUAAGAAAGCUGGGAGAAGGCUGUUUACUCUUUCU	MIMAT0004550 hsa-miR-30c-2-3p	CUGGGAGAAGGCUGUUUACUCU	miR-30c was cloned from mouse heart and brain tissues by Lagos-Quintana etal. . Two human hairpin precursor sequences are predicted based onhomology with the mouse sequences, on chromosomes 1 (MIR:MI0000736) and 6(MIR:MI0000254) . Expression of miR-30c was later independentlyverified in human HL-60 leukemia cells .
MI0000736	MIPF0000005	ACCAUGCUGUAGUGUGUGUAAACAUCCUACACUCUCAGCUGUGAGCUCAAGGUGGCUGGGAGAGGGUUGUUUACUCCUUCUGCCAUGGA	MIMAT0004674 hsa-miR-30c-1-3p	CUGGGAGAGGGUUGUUUACUCC	miR-30c was cloned from mouse heart and brain tissues by Lagos-Quintana etal. . Two human hairpin precursor sequences are predicted based onhomology with the mouse sequences, on chromosomes 1 (MIR:MI0000736) and 6(MIR:MI0000254) . Expression of miR-30c was later validated in humanHL-60 leukemia cells .
MI0000736	MIPF0000005	ACCAUGCUGUAGUGUGUGUAAACAUCCUACACUCUCAGCUGUGAGCUCAAGGUGGCUGGGAGAGGGUUGUUUACUCCUUCUGCCAUGGA	MIMAT0000244 hsa-miR-30c-5p	UGUAAACAUCCUACACUCUCAGC	miR-30c was cloned from mouse heart and brain tissues by Lagos-Quintana etal. . Two human hairpin precursor sequences are predicted based onhomology with the mouse sequences, on chromosomes 1 (MIR:MI0000736) and 6(MIR:MI0000254) . Expression of miR-30c was later validated in humanHL-60 leukemia cells .
MI0000254	MIPF0000005	AGAUACUGUAAACAUCCUACACUCUCAGCUGUGGAAAGUAAGAAAGCUGGGAGAAGGCUGUUUACUCUUUCU	MIMAT0004550 hsa-miR-30c-2-3p	CUGGGAGAAGGCUGUUUACUCU	miR-30c was cloned from mouse heart and brain tissues by Lagos-Quintana etal. . Two human hairpin precursor sequences are predicted based onhomology with the mouse sequences, on chromosomes 1 (MIR:MI0000736) and 6(MIR:MI0000254) . Expression of miR-30c was later independentlyverified in human HL-60 leukemia cells .
MI0000736	MIPF0000005	ACCAUGCUGUAGUGUGUGUAAACAUCCUACACUCUCAGCUGUGAGCUCAAGGUGGCUGGGAGAGGGUUGUUUACUCCUUCUGCCAUGGA	MIMAT0004674 hsa-miR-30c-1-3p	CUGGGAGAGGGUUGUUUACUCC	miR-30c was cloned from mouse heart and brain tissues by Lagos-Quintana etal. . Two human hairpin precursor sequences are predicted based onhomology with the mouse sequences, on chromosomes 1 (MIR:MI0000736) and 6(MIR:MI0000254) . Expression of miR-30c was later validated in humanHL-60 leukemia cells .
MI0000736	MIPF0000005	ACCAUGCUGUAGUGUGUGUAAACAUCCUACACUCUCAGCUGUGAGCUCAAGGUGGCUGGGAGAGGGUUGUUUACUCCUUCUGCCAUGGA	MIMAT0000244 hsa-miR-30c-5p	UGUAAACAUCCUACACUCUCAGC	miR-30c was cloned from mouse heart and brain tissues by Lagos-Quintana etal. . Two human hairpin precursor sequences are predicted based onhomology with the mouse sequences, on chromosomes 1 (MIR:MI0000736) and 6(MIR:MI0000254) . Expression of miR-30c was later validated in humanHL-60 leukemia cells .
MI0000254	MIPF0000005	AGAUACUGUAAACAUCCUACACUCUCAGCUGUGGAAAGUAAGAAAGCUGGGAGAAGGCUGUUUACUCUUUCU	MIMAT0004550 hsa-miR-30c-2-3p	CUGGGAGAAGGCUGUUUACUCU	miR-30c was cloned from mouse heart and brain tissues by Lagos-Quintana etal. . Two human hairpin precursor sequences are predicted based onhomology with the mouse sequences, on chromosomes 1 (MIR:MI0000736) and 6(MIR:MI0000254) . Expression of miR-30c was later independentlyverified in human HL-60 leukemia cells .
MI0000736	MIPF0000005	ACCAUGCUGUAGUGUGUGUAAACAUCCUACACUCUCAGCUGUGAGCUCAAGGUGGCUGGGAGAGGGUUGUUUACUCCUUCUGCCAUGGA	MIMAT0004674 hsa-miR-30c-1-3p	CUGGGAGAGGGUUGUUUACUCC	miR-30c was cloned from mouse heart and brain tissues by Lagos-Quintana etal. . Two human hairpin precursor sequences are predicted based onhomology with the mouse sequences, on chromosomes 1 (MIR:MI0000736) and 6(MIR:MI0000254) . Expression of miR-30c was later validated in humanHL-60 leukemia cells .
MI0000736	MIPF0000005	ACCAUGCUGUAGUGUGUGUAAACAUCCUACACUCUCAGCUGUGAGCUCAAGGUGGCUGGGAGAGGGUUGUUUACUCCUUCUGCCAUGGA	MIMAT0000244 hsa-miR-30c-5p	UGUAAACAUCCUACACUCUCAGC	miR-30c was cloned from mouse heart and brain tissues by Lagos-Quintana etal. . Two human hairpin precursor sequences are predicted based onhomology with the mouse sequences, on chromosomes 1 (MIR:MI0000736) and 6(MIR:MI0000254) . Expression of miR-30c was later validated in humanHL-60 leukemia cells .
MI0000736	MIPF0000005	ACCAUGCUGUAGUGUGUGUAAACAUCCUACACUCUCAGCUGUGAGCUCAAGGUGGCUGGGAGAGGGUUGUUUACUCCUUCUGCCAUGGA	MIMAT0000244 hsa-miR-30c-5p	UGUAAACAUCCUACACUCUCAGC	miR-30c was cloned from mouse heart and brain tissues by Lagos-Quintana etal. . Two human hairpin precursor sequences are predicted based onhomology with the mouse sequences, on chromosomes 1 (MIR:MI0000736) and 6(MIR:MI0000254) . Expression of miR-30c was later validated in humanHL-60 leukemia cells .
MI0000736	MIPF0000005	ACCAUGCUGUAGUGUGUGUAAACAUCCUACACUCUCAGCUGUGAGCUCAAGGUGGCUGGGAGAGGGUUGUUUACUCCUUCUGCCAUGGA	MIMAT0000244 hsa-miR-30c-5p	UGUAAACAUCCUACACUCUCAGC	miR-30c was cloned from mouse heart and brain tissues by Lagos-Quintana etal. . Two human hairpin precursor sequences are predicted based onhomology with the mouse sequences, on chromosomes 1 (MIR:MI0000736) and 6(MIR:MI0000254) . Expression of miR-30c was later validated in humanHL-60 leukemia cells .
MI0000736	MIPF0000005	ACCAUGCUGUAGUGUGUGUAAACAUCCUACACUCUCAGCUGUGAGCUCAAGGUGGCUGGGAGAGGGUUGUUUACUCCUUCUGCCAUGGA	MIMAT0000244 hsa-miR-30c-5p	UGUAAACAUCCUACACUCUCAGC	miR-30c was cloned from mouse heart and brain tissues by Lagos-Quintana etal. . Two human hairpin precursor sequences are predicted based onhomology with the mouse sequences, on chromosomes 1 (MIR:MI0000736) and 6(MIR:MI0000254) . Expression of miR-30c was later validated in humanHL-60 leukemia cells .
MI0000736	MIPF0000005	ACCAUGCUGUAGUGUGUGUAAACAUCCUACACUCUCAGCUGUGAGCUCAAGGUGGCUGGGAGAGGGUUGUUUACUCCUUCUGCCAUGGA	MIMAT0000244 hsa-miR-30c-5p	UGUAAACAUCCUACACUCUCAGC	miR-30c was cloned from mouse heart and brain tissues by Lagos-Quintana etal. . Two human hairpin precursor sequences are predicted based onhomology with the mouse sequences, on chromosomes 1 (MIR:MI0000736) and 6(MIR:MI0000254) . Expression of miR-30c was later validated in humanHL-60 leukemia cells .
MI0000736	MIPF0000005	ACCAUGCUGUAGUGUGUGUAAACAUCCUACACUCUCAGCUGUGAGCUCAAGGUGGCUGGGAGAGGGUUGUUUACUCCUUCUGCCAUGGA	MIMAT0000244 hsa-miR-30c-5p	UGUAAACAUCCUACACUCUCAGC	miR-30c was cloned from mouse heart and brain tissues by Lagos-Quintana etal. . Two human hairpin precursor sequences are predicted based onhomology with the mouse sequences, on chromosomes 1 (MIR:MI0000736) and 6(MIR:MI0000254) . Expression of miR-30c was later validated in humanHL-60 leukemia cells .

link to database

TargetScanS 6.2 | MicroCosm | microRNA.org | miRNAMap 2.0

Interacted genes from RAID,miRTarBase

LACTB2,CCDC117,HMBOX1,LIMA1,UXT,TNFSF10,PNKD,RPS27A,INPP5F,PARVG,KLHDC5,RPS3,SMAD1,MTCH2,CEP152
more » LACTB2,CCDC117,HMBOX1,LIMA1,UXT,TNFSF10,PNKD,RPS27A,INPP5F,PARVG,KLHDC5,RPS3,SMAD1,MTCH2,CEP152,AIFM1,CADPS2,SCN11A,EP300,STARD7,CDH1,MTA1,MGLL,MLL2,E2F3,DNAJB14,TGIF2,WDR5,EED,HUWE1,RAPGEFL1,ITGA4,LLPH,PPM1H,YTHDC2,NLE1,UBE2NL,RBM14,ITGB3,NFE2L1,MARCKSL1,REXO2,HUS1,DYRK1B,HPRT1,MTPAP,RUNX2,LYRM2,C1QBP,RBM3,CKAP4,CPSF7,BCCIP,TM9SF3,SEMA6A,BCL6,ZNF780B,VIM,PDAP1,SCD5,TMX3,ARF1,SEC63,MARK4,FAM134C,ARHGEF12,RAB18,HNRNPK,UBE2I,AGPAT5,TRA2B,SMARCE1,GAPVD1,CSNK1E,C16orf70,GZF1,BLMH,JUP,RNF34,GDI2,RPL39,MGEA5,KCTD3,NFYB,NDNL2,HMGN2,TMEM14E,TWF1,ARF3,HNRNPC,CBY1,HDAC4,DDOST,FTSJ1,TKT,HMG20A,PPIA,FEM1B,MED1,LIN28A,TIMP3,RPL32,DDB1,MTDH,CASC4,HNRNPU,ZNF829,PITPNB,PPP1R12A,NEDD9,UBXN1,UBE2O,TRA2A,ERLIN1,EIF2A,MGAT2,KLHL15,FDPS,SIAH2,ZNF506,HNRNPA2B1,ZNF687,SOCS1,TMEM120B,SMU1,POU2F1,SOCS3,ALDH5A1,IKZF4,ARHGEF6,PTBP3,HMGXB4,DIS3,TBL1XR1,STARD5,ND6,RPS12,DHX8,LONP2,MUC17,MATR3,TMCO3,PTAR1,SENP3,HSPA1A,ERI1,ZNF668,RNPS1,ECT2,PAM,MRPS16,ETS1,POM121,CTSC,APLN,GNB2L1,OTP,CFL2,EIF2S3,HMGA1,LIN9,PFN1,PIK3R2,HERC4,ESYT1,MED13,MRPL38,NUDT11,CHMP4C,UTP15,KRAS,VAC14,SHFM1,CSF1,ARCN1,MAP2K1,SLC7A2,B3GNT5,CSDE1,CPOX,OTUD7A,ZNF146,AP3S1,ARHGAP44,HSP90AA1,SNX2,BIRC5,SNRNP40,PRKAB2,KLC2,DLC1,RAC3,NONO,SERPINE1,IPO9,HSPH1,HSPA14,GTF3C3,PKM2,PLCB1,RASA1,ELOVL4,SUZ12,RAC1,C1orf55,HSPA4,ATG5,POLQ,MXI1,SLC25A12,RTN4,SDF2L1,EEF1A1,NEDD4,UQCRC1,RPL27A,TTC19,SLC25A38,CASP3,KREMEN1,SNAPC4,DPYSL2,RRM2,SOX4,TNRC6A,SRRT,CAPZA1,UBE3C,ABCE1,ABI2,ERLIN2,CNO,HNRPDL,CELSR3,CHD1,SLC39A1,SRPR,SLC39A8,CAMKV,EIF2C1,USP37,SUN2,HSPA1B,ARFGAP1,PRCP,CUL2,UBE2D2

KEGG pathways enriched for interacted genes

pathway name

pathway description

target genes enrich in pathway

p-value

hsa04120	Ubiquitin mediated proteolysis	HUWE1,HERC4,CUL2,UBE2D2,UBE2O,UBE2I,SOCS3,UBE2NL,SOCS1,NEDD4,UBE3C,DDB1,	1.58E-5
hsa04810	Regulation of actin cytoskeleton	ABI2,RAC3,ARHGEF6,MAP2K1,ARHGEF12,KRAS,ITGB3,CFL2,ITGA4,PPP1R12A,RAC1,PIK3R2,PFN1,	2.30E-4
hsa05211	Renal cell carcinoma	CUL2,EP300,MAP2K1,ETS1,KRAS,RAC1,PIK3R2,	1.08E-2
hsa05212	Pancreatic cancer	RAC3,ARHGEF6,MAP2K1,KRAS,RAC1,E2F3,PIK3R2,	1.25E-2
hsa05210	Colorectal cancer	RAC3,MAP2K1,BIRC5,KRAS,RAC1,CASP3,PIK3R2,	2.78E-2

hsa05200	Pathways in cancer	RAC3,EP300,MAP2K1,BIRC5,KRAS,JUP,CASP3,E2F3,CUL2,HSP90AA1,ETS1,RAC1,PIK3R2,CDH1,	3.14E-2
hsa03040	Spliceosome	HSPA1B,TRA2B,HNRNPC,HSPA1A,HNRNPU,SNRNP40,DHX8,HNRNPK,TRA2A,	5.14E-2
hsa04360	Axon guidance	DPYSL2,RAC3,SEMA6A,ARHGEF12,KRAS,RAC1,CFL2,RASA1,	5.85E-2
hsa03010	Ribosome	RPL39,RPL32,RPS12,RPS3,RPL27A,RPS27A,	1.53E-1
hsa05215	Prostate cancer	HSP90AA1,EP300,MAP2K1,KRAS,E2F3,PIK3R2,	1.68E-1
hsa04650	Natural killer cell mediated cytotoxicity	RAC3,MAP2K1,KRAS,TNFSF10,RAC1,CASP3,PIK3R2,	2.43E-1
hsa04720	Long-term potentiation	PLCB1,EP300,MAP2K1,PPP1R12A,KRAS,	2.73E-1
hsa05218	Melanoma	MAP2K1,KRAS,E2F3,PIK3R2,CDH1,	3.14E-1
hsa05219	Bladder cancer	MAP2K1,KRAS,E2F3,CDH1,	3.33E-1
hsa04662	B cell receptor signaling pathway	RAC3,MAP2K1,KRAS,RAC1,PIK3R2,	3.73E-1
hsa04370	VEGF signaling pathway	RAC3,MAP2K1,KRAS,RAC1,PIK3R2,	3.73E-1
hsa04664	Fc epsilon RI signaling pathway	RAC3,MAP2K1,KRAS,RAC1,PIK3R2,	4.22E-1
hsa04930	Type II diabetes mellitus	SOCS3,SOCS1,PKM2,PIK3R2,	4.44E-1
hsa04510	Focal adhesion	ITGA4,RAC3,MAP2K1,PPP1R12A,ITGB3,RAC1,PIK3R2,PARVG,	5.25E-1
hsa05213	Endometrial cancer	MAP2K1,KRAS,PIK3R2,CDH1,	5.70E-1
hsa05223	Non-small cell lung cancer	MAP2K1,KRAS,E2F3,PIK3R2,	6.25E-1
hsa04320	Dorso-ventral axis formation	MAP2K1,ETS1,KRAS,	6.59E-1
hsa05221	Acute myeloid leukemia	MAP2K1,KRAS,JUP,PIK3R2,	7.41E-1
hsa04666	Fc gamma R-mediated phagocytosis	MAP2K1,RAC1,CFL2,PIK3R2,MARCKSL1,	7.62E-1
hsa04910	Insulin signaling pathway	PRKAB2,MAP2K1,KRAS,SOCS3,SOCS1,PIK3R2,	7.74E-1
hsa05216	Thyroid cancer	MAP2K1,KRAS,CDH1,	8.55E-1
hsa05214	Glioma	MAP2K1,KRAS,E2F3,PIK3R2,	9.00E-1

Gene ontology terms enriched for interacted genes

GO terms

GO terms description

target genes enrich in GO term

p-value

GO:0044265	cellular macromolecule catabolic process	SENP3,UBE2I,SOCS1,NEDD4,USP37,LIN28A,KLHL15,ERLIN1,RNPS1,UBE2O,SOCS3,SIAH2,UBE3C,DDB1,FEM1B,HSPA1B,HERC4,UBXN1,HSPA1A,EIF2C1,TBL1XR1,RNF34,UBE2NL,ERLIN2,CASP3,RPS27A,HUWE1,ABCE1,CUL2,UBE2D2,AIFM1,OTUD7A,	8.39E-7
GO:0009057	macromolecule catabolic process	SENP3,UBE2I,SOCS1,NEDD4,USP37,LIN28A,KLHL15,ERLIN1,RNPS1,UBE2O,SOCS3,SIAH2,UBE3C,DDB1,FEM1B,HSPA1B,HERC4,UBXN1,HSPA1A,EIF2C1,TBL1XR1,RNF34,UBE2NL,ERLIN2,CASP3,RPS27A,HUWE1,ABCE1,CUL2,UBE2D2,MGEA5,AIFM1,OTUD7A,	1.30E-6
GO:0035195	gene silencing by miRNA	SRRT,EIF2C1,TNRC6A,RBM3,LIN28A,SMAD1,	4.56E-6
GO:0031047	gene silencing by RNA	SRRT,EIF2C1,TNRC6A,ERI1,RBM3,LIN28A,SMAD1,	1.01E-5
GO:0035194	posttranscriptional gene silencing by RNA	SRRT,EIF2C1,TNRC6A,RBM3,LIN28A,SMAD1,	1.42E-5

GO:0016441	posttranscriptional gene silencing	SRRT,EIF2C1,TNRC6A,RBM3,LIN28A,SMAD1,	1.42E-5
GO:0010605	negative regulation of macromolecule metabolic process	RUNX2,SRRT,SUZ12,ERI1,UBE2I,NEDD4,SOCS1,CBY1,RPS3,LIN28A,HUS1,MTDH,BCL6,ATG5,GZF1,TBL1XR1,EIF2C1,HDAC4,ITGB3,RPS27A,EED,TNRC6A,MGEA5,POU2F1,RBM3,TIMP3,SMARCE1,SMAD1,	2.65E-5
GO:0019941	modification-dependent protein catabolic process	SENP3,HERC4,UBXN1,TBL1XR1,RNF34,UBE2I,UBE2NL,SOCS1,NEDD4,ERLIN2,USP37,RPS27A,HUWE1,KLHL15,ERLIN1,CUL2,UBE2D2,UBE2O,SOCS3,SIAH2,OTUD7A,UBE3C,DDB1,FEM1B,	2.96E-5
GO:0043632	modification-dependent macromolecule catabolic process	SENP3,HERC4,UBXN1,TBL1XR1,RNF34,UBE2I,UBE2NL,SOCS1,NEDD4,ERLIN2,USP37,RPS27A,HUWE1,KLHL15,ERLIN1,CUL2,UBE2D2,UBE2O,SOCS3,SIAH2,OTUD7A,UBE3C,DDB1,FEM1B,	2.96E-5
GO:0006396	RNA processing	UTP15,CPSF7,SRRT,TRA2B,PTBP3,NONO,HNRPDL,MTPAP,ERI1,SNRNP40,LIN28A,RNPS1,HNRNPC,FTSJ1,HNRNPU,DIS3,DHX8,RBM3,HNRNPA2B1,HNRNPK,RBM14,TRA2A,SMAD1,	4.22E-5
GO:0051603	proteolysis involved in cellular protein catabolic process	SENP3,HERC4,UBXN1,TBL1XR1,RNF34,UBE2I,UBE2NL,SOCS1,NEDD4,ERLIN2,USP37,RPS27A,HUWE1,KLHL15,ERLIN1,CUL2,UBE2D2,UBE2O,SOCS3,SIAH2,OTUD7A,UBE3C,DDB1,FEM1B,	5.88E-5
GO:0044257	cellular protein catabolic process	SENP3,HERC4,UBXN1,TBL1XR1,RNF34,UBE2I,UBE2NL,SOCS1,NEDD4,ERLIN2,USP37,RPS27A,HUWE1,KLHL15,ERLIN1,CUL2,UBE2D2,UBE2O,SOCS3,SIAH2,OTUD7A,UBE3C,DDB1,FEM1B,	6.34E-5
GO:0030163	protein catabolic process	SENP3,HERC4,UBXN1,TBL1XR1,RNF34,UBE2I,UBE2NL,SOCS1,NEDD4,ERLIN2,USP37,RPS27A,HUWE1,KLHL15,ERLIN1,CUL2,UBE2D2,UBE2O,SOCS3,SIAH2,OTUD7A,UBE3C,DDB1,FEM1B,	1.01E-4
GO:0016458	gene silencing	SRRT,EIF2C1,TNRC6A,ERI1,RBM3,LIN28A,SMAD1,	2.21E-4
GO:0010629	negative regulation of gene expression	RUNX2,SRRT,SUZ12,TBL1XR1,EIF2C1,HDAC4,ERI1,UBE2I,NEDD4,CBY1,LIN28A,MTDH,EED,TNRC6A,POU2F1,RBM3,BCL6,SMARCE1,GZF1,SMAD1,	3.26E-4
GO:0010033	response to organic substance	LONP2,SRRT,EP300,CTSC,KRAS,SOCS1,LIN28A,HSP90AA1,SOCS3,AP3S1,HSPA1B,HPRT1,HSPH1,HSPA1A,MAP2K1,HDAC4,HSPA4,CASP3,DDOST,MGEA5,RBM3,TIMP3,RBM14,SMAD1,UQCRC1,CDH1,	3.46E-4
GO:0006511	ubiquitin-dependent protein catabolic process	UBXN1,TBL1XR1,UBE2NL,UBE2I,NEDD4,ERLIN2,USP37,RPS27A,ERLIN1,CUL2,UBE2D2,SIAH2,DDB1,	4.01E-4
GO:0051640	organelle localization	UXT,ARF1,SEMA6A,ARFGAP1,MAP2K1,BIRC5,ARCN1,SUN2,	5.64E-4
GO:0016071	mRNA metabolic process	HSPA1B,CPSF7,PTBP3,TRA2B,NONO,HSPA1A,EIF2C1,MTPAP,SNRNP40,RNPS1,HNRNPC,HNRNPU,DHX8,HNRNPA2B1,HNRNPK,RBM14,TRA2A,	6.68E-4
GO:0051656	establishment of organelle localization	UXT,ARF1,ARFGAP1,MAP2K1,BIRC5,ARCN1,SUN2,	6.92E-4
GO:0035196	gene silencing by miRNA, production of miRNAs	SRRT,RBM3,LIN28A,SMAD1,	7.31E-4
GO:0006508	proteolysis	LONP2,SENP3,CTSC,BLMH,UBE2I,SOCS1,NEDD4,USP37,KLHL15,ERLIN1,UBE2O,SOCS3,SIAH2,UBE3C,DDB1,FEM1B,HERC4,UBXN1,TBL1XR1,RNF34,UBE2NL,SHFM1,ERLIN2,CASP3,RPS27A,PRCP,HUWE1,CUL2,UBE2D2,OTUD7A,UQCRC1,	8.78E-4
GO:0031050	dsRNA fragmentation	SRRT,RBM3,LIN28A,SMAD1,	9.40E-4
GO:0043068	positive regulation of programmed cell death	ECT2,ARHGEF6,SOX4,ARHGEF12,TNFSF10,RPS3,DLC1,RPS27A,CASP3,CUL2,MARK4,ETS1,TIMP3,BCL6,AIFM1,RAC1,FEM1B,	1.19E-2
GO:0040029	regulation of gene expression, epigenetic	SRRT,EIF2C1,TNRC6A,RBM3,HMGA1,LIN28A,SMAD1,	1.23E-2
GO:0010942	positive regulation of cell death	ECT2,ARHGEF6,SOX4,ARHGEF12,TNFSF10,RPS3,DLC1,RPS27A,CASP3,CUL2,MARK4,ETS1,TIMP3,BCL6,AIFM1,RAC1,FEM1B,	1.25E-2
GO:0006917	induction of apoptosis	ECT2,ARHGEF6,ARHGEF12,TNFSF10,RPS3,RPS27A,CASP3,DLC1,CUL2,ETS1,TIMP3,AIFM1,RAC1,FEM1B,	1.48E-2
GO:0051252	regulation of RNA metabolic process	ZNF829,RUNX2,MED13,NFE2L1,RAB18,ZNF146,SUZ12,EP300,SOX4,OTP,HMG20A,UBE2I,NEDD4,CHD1,CBY1,LIN28A,MTDH,TGIF2,NFYB,DYRK1B,HNRNPU,HMGXB4,HMGN2,BCL6,GZF1,MAP2K1,TBL1XR1,HDAC4,NDNL2,HMGA1,E2F3,MLL2,MED1,RASA1,ZNF506,HMBOX1,MTA1,ZNF780B,ETS1,CSDE1,POU2F1,RBM14,SMARCE1,SMAD1,PFN1,	1.51E-2
GO:0006397	mRNA processing	CPSF7,PTBP3,TRA2B,NONO,MTPAP,SNRNP40,HNRNPC,RNPS1,HNRNPU,HNRNPA2B1,HNRNPK,DHX8,RBM14,TRA2A,	1.53E-2
GO:0012502	induction of programmed cell death	ECT2,ARHGEF6,ARHGEF12,TNFSF10,RPS3,RPS27A,CASP3,DLC1,CUL2,ETS1,TIMP3,AIFM1,RAC1,FEM1B,	1.53E-2
GO:0043067	regulation of programmed cell death	SOX4,ARHGEF6,BIRC5,KRAS,TNFSF10,RPS3,DLC1,MARK4,SOCS3,BCL6,ATG5,FEM1B,ECT2,HSPA1B,RTN4,HSPA1A,ARHGEF12,CASP3,RPS27A,RASA1,CUL2,ETS1,TIMP3,RAC1,AIFM1,CDH1,	1.80E-2
GO:0010941	regulation of cell death	SOX4,ARHGEF6,BIRC5,KRAS,TNFSF10,RPS3,DLC1,MARK4,SOCS3,BCL6,ATG5,FEM1B,ECT2,HSPA1B,RTN4,HSPA1A,ARHGEF12,CASP3,RPS27A,RASA1,CUL2,ETS1,TIMP3,RAC1,AIFM1,CDH1,	1.89E-2
GO:0051056	regulation of small GTPase mediated signal transduction	ECT2,GAPVD1,CSF1,ARHGEF6,ARFGAP1,MAP2K1,ARHGEF12,KRAS,BCL6,RAC1,DLC1,RASA1,	1.95E-2
GO:0016567	protein ubiquitination	HUWE1,SUZ12,UBE2D2,NEDD4,SIAH2,UBE3C,DDB1,RPS27A,	2.53E-2
GO:0000375	RNA splicing, via transesterification reactions	CPSF7,TRA2B,RNPS1,HNRNPC,HNRNPU,SNRNP40,HNRNPK,HNRNPA2B1,TRA2A,	2.67E-2
GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	CPSF7,TRA2B,RNPS1,HNRNPC,HNRNPU,SNRNP40,HNRNPK,HNRNPA2B1,TRA2A,	2.67E-2
GO:0000398	nuclear mRNA splicing, via spliceosome	CPSF7,TRA2B,RNPS1,HNRNPC,HNRNPU,SNRNP40,HNRNPK,HNRNPA2B1,TRA2A,	2.67E-2
GO:0043065	positive regulation of apoptosis	ECT2,ARHGEF6,SOX4,ARHGEF12,TNFSF10,RPS3,DLC1,RPS27A,CASP3,CUL2,ETS1,TIMP3,BCL6,AIFM1,RAC1,FEM1B,	2.94E-2
GO:0006355	regulation of transcription, DNA-dependent	ZNF829,RUNX2,MED13,NFE2L1,RAB18,ZNF146,SUZ12,SOX4,EP300,OTP,HMG20A,UBE2I,NEDD4,CHD1,CBY1,LIN28A,MTDH,TGIF2,NFYB,DYRK1B,HMGXB4,HMGN2,BCL6,GZF1,MAP2K1,TBL1XR1,HDAC4,NDNL2,HMGA1,E2F3,MLL2,MED1,ZNF506,HMBOX1,MTA1,ZNF780B,ETS1,CSDE1,POU2F1,RBM14,SMARCE1,SMAD1,PFN1,	3.11E-2
GO:0012501	programmed cell death	ECT2,RTN4,SEMA6A,EP300,ARHGEF6,BIRC5,ARHGEF12,KRAS,RNF34,TNFSF10,RPS3,DLC1,CASP3,RPS27A,PKM2,SIAH2,RAC1,AIFM1,ATG5,FEM1B,	3.12E-2
GO:0042981	regulation of apoptosis	SOX4,ARHGEF6,BIRC5,KRAS,TNFSF10,DLC1,RPS3,SOCS3,BCL6,ATG5,FEM1B,ECT2,HSPA1B,RTN4,HSPA1A,ARHGEF12,RPS27A,CASP3,RASA1,CUL2,ETS1,TIMP3,AIFM1,RAC1,CDH1,	3.38E-2
GO:0008219	cell death	ECT2,HPRT1,RTN4,SEMA6A,EP300,ARHGEF6,BIRC5,ARHGEF12,KRAS,RNF34,TNFSF10,RPS3,DLC1,CASP3,RPS27A,MGEA5,PKM2,SIAH2,RAC1,AIFM1,ATG5,FEM1B,	3.99E-2
GO:0016265	death	ECT2,HPRT1,RTN4,SEMA6A,EP300,ARHGEF6,BIRC5,ARHGEF12,KRAS,RNF34,TNFSF10,RPS3,DLC1,CASP3,RPS27A,MGEA5,PKM2,SIAH2,RAC1,AIFM1,ATG5,FEM1B,	4.32E-2
GO:0032446	protein modification by small protein conjugation	HUWE1,SUZ12,UBE2D2,NEDD4,SIAH2,UBE3C,DDB1,RPS27A,	4.51E-2
GO:0006414	translational elongation	RPL39,RPL32,RPS12,EEF1A1,RPS3,RPL27A,RPS27A,	4.86E-2
GO:0008380	RNA splicing	CPSF7,TRA2B,NONO,RNPS1,HNRNPC,HNRNPU,SNRNP40,DHX8,HNRNPK,HNRNPA2B1,RBM14,TRA2A,	4.86E-2
GO:0010558	negative regulation of macromolecule biosynthetic process	RUNX2,SUZ12,EIF2C1,TBL1XR1,HDAC4,ITGB3,UBE2I,NEDD4,CBY1,HUS1,MTDH,EED,TNRC6A,MGEA5,POU2F1,BCL6,SMARCE1,GZF1,	5.13E-2
GO:0051173	positive regulation of nitrogen compound metabolic process	RUNX2,HPRT1,MED13,EP300,SOX4,MAP2K1,TBL1XR1,HDAC4,HMGA1,E2F3,RPS27A,MED1,HSP90AA1,NFYB,DYRK1B,MGEA5,ETS1,POU2F1,RBM14,SMAD1,	5.49E-2
GO:0046578	regulation of Ras protein signal transduction	ECT2,CSF1,ARHGEF6,ARFGAP1,MAP2K1,ARHGEF12,KRAS,BCL6,RAC1,DLC1,	5.51E-2
GO:0006512	ubiquitin cycle	UBE2D2,SOCS3,SOCS1,USP37,	5.86E-2
GO:0006915	apoptosis	ECT2,RTN4,SEMA6A,EP300,ARHGEF6,BIRC5,ARHGEF12,KRAS,RNF34,TNFSF10,RPS3,DLC1,CASP3,RPS27A,SIAH2,RAC1,AIFM1,ATG5,FEM1B,	5.96E-2
GO:0043331	response to dsRNA	SRRT,RBM3,LIN28A,SMAD1,	6.59E-2
GO:0042493	response to drug	SCN11A,EP300,CPOX,BLMH,HDAC4,SOCS3,SOCS1,ATG5,SMAD1,CDH1,	6.64E-2
GO:0046907	intracellular transport	SRPR,LONP2,UXT,C16orf70,SEC63,MAP2K1,ARFGAP1,ARCN1,NEDD4,SLC25A12,ARF1,HSP90AA1,SNX2,MGEA5,KLC2,HMGXB4,BCL6,AP3S1,IPO9,CNO,	6.76E-2
GO:0008624	induction of apoptosis by extracellular signals	ECT2,ARHGEF6,ARHGEF12,TIMP3,RAC1,CASP3,RPS27A,	7.98E-2
GO:0009890	negative regulation of biosynthetic process	RUNX2,SUZ12,EIF2C1,TBL1XR1,HDAC4,ITGB3,UBE2I,NEDD4,CBY1,HUS1,MTDH,EED,TNRC6A,MGEA5,POU2F1,BCL6,SMARCE1,GZF1,	8.03E-2
GO:0051254	positive regulation of RNA metabolic process	RUNX2,MED13,EP300,SOX4,MAP2K1,TBL1XR1,HDAC4,HMGA1,E2F3,MED1,NFYB,ETS1,DYRK1B,POU2F1,RBM14,SMAD1,	8.22E-2
GO:0030036	actin cytoskeleton organization	ABI2,RAC3,CAPZA1,NEDD9,KRAS,BCL6,LIMA1,RAC1,PFN1,DLC1,	8.81E-2
GO:0048205	COPI coating of Golgi vesicle	ARF1,ARFGAP1,ARCN1,	9.94E-2
GO:0048200	Golgi transport vesicle coating	ARF1,ARFGAP1,ARCN1,	9.94E-2
GO:0048194	Golgi vesicle budding	ARF1,ARFGAP1,ARCN1,	9.94E-2

KEGG pathways and Gene Ontology terms enriched for the interacted genes of ncRNA from RAID and miRTarBase.

disease name	related genes	p-value