ncRNADetailInformation

Detail Information
Functional analysis

miRNA name

pre-miRNA

family

pre-miRNA Sequence

mature-miRNA

mature sequence

pre-miRNA description

miR-15b

MI0000438	MIPF0000006	UUGAGGCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGAAAUUCAU	MIMAT0000417 hsa-miR-15b-5p	UAGCAGCACAUCAUGGUUUACA	This miRNA sequence was predicted based on homology to a verified miRNAfrom mouse . Michael et al. subsequently verified expression ofmiR-15b in human .
MI0000438	MIPF0000006	UUGAGGCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGAAAUUCAU	MIMAT0004586 hsa-miR-15b-3p	CGAAUCAUUAUUUGCUGCUCUA	This miRNA sequence was predicted based on homology to a verified miRNAfrom mouse . Michael et al. subsequently verified expression ofmiR-15b in human .
MI0000438	MIPF0000006	UUGAGGCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGAAAUUCAU	MIMAT0000417 hsa-miR-15b-5p	UAGCAGCACAUCAUGGUUUACA	This miRNA sequence was predicted based on homology to a verified miRNAfrom mouse . Michael et al. subsequently verified expression ofmiR-15b in human .
MI0000438	MIPF0000006	UUGAGGCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGAAAUUCAU	MIMAT0004586 hsa-miR-15b-3p	CGAAUCAUUAUUUGCUGCUCUA	This miRNA sequence was predicted based on homology to a verified miRNAfrom mouse . Michael et al. subsequently verified expression ofmiR-15b in human .
MI0000438	MIPF0000006	UUGAGGCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGAAAUUCAU	MIMAT0000417 hsa-miR-15b-5p	UAGCAGCACAUCAUGGUUUACA	This miRNA sequence was predicted based on homology to a verified miRNAfrom mouse . Michael et al. subsequently verified expression ofmiR-15b in human .
MI0000438	MIPF0000006	UUGAGGCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGAAAUUCAU	MIMAT0004586 hsa-miR-15b-3p	CGAAUCAUUAUUUGCUGCUCUA	This miRNA sequence was predicted based on homology to a verified miRNAfrom mouse . Michael et al. subsequently verified expression ofmiR-15b in human .
MI0000438	MIPF0000006	UUGAGGCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGAAAUUCAU	MIMAT0000417 hsa-miR-15b-5p	UAGCAGCACAUCAUGGUUUACA	This miRNA sequence was predicted based on homology to a verified miRNAfrom mouse . Michael et al. subsequently verified expression ofmiR-15b in human .
MI0000438	MIPF0000006	UUGAGGCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGAAAUUCAU	MIMAT0004586 hsa-miR-15b-3p	CGAAUCAUUAUUUGCUGCUCUA	This miRNA sequence was predicted based on homology to a verified miRNAfrom mouse . Michael et al. subsequently verified expression ofmiR-15b in human .
MI0000438	MIPF0000006	UUGAGGCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGAAAUUCAU	MIMAT0000417 hsa-miR-15b-5p	UAGCAGCACAUCAUGGUUUACA	This miRNA sequence was predicted based on homology to a verified miRNAfrom mouse . Michael et al. subsequently verified expression ofmiR-15b in human .
MI0000438	MIPF0000006	UUGAGGCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGAAAUUCAU	MIMAT0000417 hsa-miR-15b-5p	UAGCAGCACAUCAUGGUUUACA	This miRNA sequence was predicted based on homology to a verified miRNAfrom mouse . Michael et al. subsequently verified expression ofmiR-15b in human .
MI0000438	MIPF0000006	UUGAGGCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGAAAUUCAU	MIMAT0000417 hsa-miR-15b-5p	UAGCAGCACAUCAUGGUUUACA	This miRNA sequence was predicted based on homology to a verified miRNAfrom mouse . Michael et al. subsequently verified expression ofmiR-15b in human .
MI0000438	MIPF0000006	UUGAGGCCUUAAAGUACUGUAGCAGCACAUCAUGGUUUACAUGCUACAGUCAAGAUGCGAAUCAUUAUUUGCUGCUCUAGAAAUUUAAGGAAAUUCAU	MIMAT0000417 hsa-miR-15b-5p	UAGCAGCACAUCAUGGUUUACA	This miRNA sequence was predicted based on homology to a verified miRNAfrom mouse . Michael et al. subsequently verified expression ofmiR-15b in human .

link to database

TargetScanS 6.2 | MicroCosm | microRNA.org | miRNAMap 2.0

Interacted genes from RAID,miRTarBase

RECK,TGOLN2,ITGA6,DHX37,TNPO3,FOXK1,BEX1,EIF2AK2,WAC,MLL2,HSP90AB1,UBE3B,EIF4A1,FBXO30,RND2
more » RECK,TGOLN2,ITGA6,DHX37,TNPO3,FOXK1,BEX1,EIF2AK2,WAC,MLL2,HSP90AB1,UBE3B,EIF4A1,FBXO30,RND2,NUP210,CDK4,VEGFA,PSMD7,ARID2,FGF5,TARDBP,IFNG,APRT,TTC1,BTAF1,RPLP0,SLC1A5,AGPAT5,LSM14A,B4GALT1,NAB1,TRAPPC1,TMC7,FADD,DDX5,PURA,PPIL1,MLL3,CYBA,ATP6V0E1,BRAT1,RBM27,ZNRF1,RAE1,UACA,NUP160,SYNJ1,HSPA8,STT3B,SERBP1,PTAR1,ETNK1,CCND1,ATP2A2,AP2M1,HNRNPM,QRICH1,FAM115C,PIK3C2B,PPTC7,SEPT2,PGD,VPS35,MTMR6,NUP214,C1orf43,C20orf29,CD44,ECHS1,RPS3A,NDFIP1,MYCBP2,ZNF217,RNF149,PRPS1,XKR9,QARS,MAP2K4,LIN28B,ZCCHC14,JAK1,MPP1,PRDX3,HNRNPH3,BCL2L2,BCL2,VOPP1,VPS13A,RLIM,TPD52,TAB2,MRPS11,PHLDB3,NAA30,NPM1,CCNE1,RPS3,AIG1,AMMECR1L,SFT2D1,CLCN6,DHX30,SLC39A14,SMAD7,MPHOSPH9,TM9SF3,PPT1,MLLT4,FAM214A,PPP1CC,AP4S1,TMCO7,HNRNPK,RPS6,DNAJC5,PXMP2,MESDC2,KIAA1530,IFNGR2,IFIH1,FANCC,THRA,VDAC2,INADL,PLSCR4,TSPAN3,CKAP5,SUPT3H,GNL3L,MCPH1,HIST2H3A,POU2F1,MAPK1,EIF5B,CRK,TMEM63B,STXBP1,PTPRF,MDH1,C6orf168,COIL,SF3B3,TXLNA,LZTR1,CHEK1,PPIL2,DENR,CPOX,CHMP7,ZFAND5,BAMBI,RAB1B,TERF2,SCCPDH,URB2,AIFM2,MARCKS,TMEM43,PTBP1,TCP1,PPP1CB,EEF1A1,TBRG4,RPL27A,LRRC41,CHPF,CYP51A1,NRIP1,RANBP10,EDC4,DSG2,C5orf15

KEGG pathways enriched for interacted genes

pathway name

pathway description

target genes enrich in pathway

p-value

hsa05200	Pathways in cancer	CRK,CCND1,BCL2,FADD,VEGFA,CDK4,JAK1,HSP90AB1,FGF5,CCNE1,ITGA6,MAPK1,	2.96E-2
hsa05212	Pancreatic cancer	CCND1,VEGFA,CDK4,JAK1,MAPK1,	1.37E-1
hsa04510	Focal adhesion	CRK,CCND1,BCL2,VEGFA,PPP1CC,PPP1CB,ITGA6,MAPK1,	1.46E-1
hsa05219	Bladder cancer	CCND1,VEGFA,CDK4,MAPK1,	1.67E-1
hsa05222	Small cell lung cancer	CCND1,BCL2,CDK4,CCNE1,ITGA6,	2.29E-1

Gene ontology terms enriched for interacted genes

GO terms

GO terms description

target genes enrich in GO term

p-value

GO:0006412	translation	EIF4A1,DENR,MRPS11,RPS3A,EEF1A1,QARS,EIF5B,EIF2AK2,RPS3,RPS6,RPL27A,RPLP0,	5.10E-4
GO:0051329	interphase of mitotic cell cycle	CCND1,BCL2,PPP1CB,CHEK1,TBRG4,CDK4,CCNE1,	5.94E-4
GO:0051325	interphase	CCND1,BCL2,PPP1CB,CHEK1,TBRG4,CDK4,CCNE1,	6.92E-4
GO:0042981	regulation of apoptosis	IFIH1,UACA,BCL2,BCL2L2,NPM1,PTPRF,B4GALT1,RPS3A,PPT1,CD44,RPS3,IFNG,FADD,VEGFA,PRDX3,DNAJC5,RPS6,AIFM2,MAPK1,	1.14E-2
GO:0000278	mitotic cell cycle	CCND1,BCL2,TARDBP,MPHOSPH9,PPP1CB,CHEK1,TBRG4,CDK4,SEPT2,PSMD7,CCNE1,CKAP5,	1.27E-2

GO:0043067	regulation of programmed cell death	IFIH1,UACA,BCL2,BCL2L2,NPM1,PTPRF,B4GALT1,RPS3A,PPT1,CD44,RPS3,IFNG,FADD,VEGFA,PRDX3,DNAJC5,RPS6,AIFM2,MAPK1,	1.28E-2
GO:0010941	regulation of cell death	IFIH1,UACA,BCL2,BCL2L2,NPM1,PTPRF,B4GALT1,RPS3A,PPT1,CD44,RPS3,IFNG,FADD,VEGFA,PRDX3,DNAJC5,RPS6,AIFM2,MAPK1,	1.33E-2
GO:0000082	G1/S transition of mitotic cell cycle	CCND1,BCL2,PPP1CB,CDK4,CCNE1,	2.39E-2
GO:0046907	intracellular transport	NUP214,VPS35,BCL2,NPM1,CHMP7,HSPA8,C6orf168,NUP160,ATP2A2,IFNG,VPS13A,AP4S1,TRAPPC1,RAE1,AP2M1,MAPK1,	2.49E-2
GO:0050658	RNA transport	NUP214,NUP210,NPM1,NUP160,CKAP5,RAE1,	2.93E-2
GO:0051236	establishment of RNA localization	NUP214,NUP210,NPM1,NUP160,CKAP5,RAE1,	2.93E-2
GO:0050657	nucleic acid transport	NUP214,NUP210,NPM1,NUP160,CKAP5,RAE1,	2.93E-2
GO:0008284	positive regulation of cell proliferation	PURA,CCND1,IFNG,BCL2,VEGFA,PRDX3,NPM1,PPP1CB,B4GALT1,TBRG4,CDK4,MAPK1,	3.06E-2
GO:0006403	RNA localization	NUP214,NUP210,NPM1,NUP160,CKAP5,RAE1,	3.34E-2
GO:0006414	translational elongation	RPS3A,EEF1A1,RPS3,RPS6,RPL27A,RPLP0,	3.49E-2
GO:0043065	positive regulation of apoptosis	IFNG,BCL2,UACA,FADD,PTPRF,B4GALT1,RPS3A,CD44,RPS3,RPS6,AIFM2,MAPK1,	4.07E-2
GO:0015031	protein transport	STXBP1,NUP214,VPS35,TNPO3,NUP210,NPM1,CHMP7,PPT1,C6orf168,NUP160,IFNG,RAB1B,SFT2D1,VPS13A,AP4S1,AP2M1,MAPK1,	4.09E-2
GO:0007548	sex differentiation	CCND1,BCL2,BCL2L2,VEGFA,B4GALT1,CCNE1,NRIP1,	4.19E-2
GO:0043068	positive regulation of programmed cell death	IFNG,BCL2,UACA,FADD,PTPRF,B4GALT1,RPS3A,CD44,RPS3,RPS6,AIFM2,MAPK1,	4.29E-2
GO:0010942	positive regulation of cell death	IFNG,BCL2,UACA,FADD,PTPRF,B4GALT1,RPS3A,CD44,RPS3,RPS6,AIFM2,MAPK1,	4.44E-2
GO:0051789	response to protein stimulus	CCND1,IFNG,BCL2,HSPA8,HSP90AB1,EIF2AK2,	4.47E-2
GO:0045184	establishment of protein localization	STXBP1,NUP214,VPS35,TNPO3,NUP210,NPM1,CHMP7,PPT1,C6orf168,NUP160,IFNG,RAB1B,SFT2D1,VPS13A,AP4S1,AP2M1,MAPK1,	4.47E-2
GO:0022402	cell cycle process	CCND1,BCL2,NPM1,CHEK1,TBRG4,SEPT2,CDK4,PSMD7,IFNG,TARDBP,MPHOSPH9,PPP1CB,CKAP5,CCNE1,	4.52E-2
GO:0033554	cellular response to stress	CCND1,TERF2,UACA,BCL2,CHEK1,EIF2AK2,RPS3,MAP2K4,IFNG,PRDX3,MRPS11,PPP1CB,FANCC,MAPK1,	4.58E-2
GO:0007049	cell cycle	CCND1,TERF2,BCL2,NPM1,CHEK1,TBRG4,SEPT2,CDK4,PSMD7,IFNG,TARDBP,PPP1CC,MPHOSPH9,PPP1CB,CCNE1,CKAP5,MAPK1,	4.88E-2
GO:0006984	ER-nuclear signaling pathway	CCND1,IFNG,EIF2AK2,ATP2A2,	5.14E-2
GO:0008406	gonad development	CCND1,BCL2,BCL2L2,VEGFA,CCNE1,NRIP1,	5.42E-2
GO:0010608	posttranscriptional regulation of gene expression	BCL2,VEGFA,SERBP1,LIN28B,CDK4,EIF5B,SMAD7,MAPK1,	5.44E-2
GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	TERF2,NPM1,NRIP1,RPS3,FOXK1,PURA,NAB1,THRA,POU2F1,NDFIP1,SMAD7,RLIM,BTAF1,	5.47E-2
GO:0015931	nucleobase, nucleoside, nucleotide and nucleic acid transport	NUP214,NUP210,NPM1,NUP160,CKAP5,RAE1,	5.62E-2
GO:0006986	response to unfolded protein	CCND1,IFNG,HSPA8,HSP90AB1,EIF2AK2,	5.64E-2
GO:0032844	regulation of homeostatic process	IFNG,TERF2,BCL2,VEGFA,CD44,SMAD7,	5.84E-2
GO:0051172	negative regulation of nitrogen compound metabolic process	TERF2,NPM1,NRIP1,RPS3,FOXK1,PURA,NAB1,THRA,POU2F1,NDFIP1,SMAD7,RLIM,BTAF1,	6.08E-2
GO:0010605	negative regulation of macromolecule metabolic process	TERF2,NPM1,LIN28B,PSMD7,HSP90AB1,RPS3,NRIP1,FOXK1,PURA,NAB1,THRA,POU2F1,NDFIP1,SMAD7,RLIM,BTAF1,	6.91E-2
GO:0008104	protein localization	STXBP1,NUP214,VPS35,NUP210,TNPO3,TERF2,NPM1,CHMP7,PPT1,C6orf168,NUP160,IFNG,RAB1B,SFT2D1,VPS13A,AP4S1,AP2M1,MAPK1,	7.24E-2
GO:0033135	regulation of peptidyl-serine phosphorylation	IFNG,BCL2,SMAD7,	8.43E-2
GO:0048608	reproductive structure development	CCND1,BCL2,BCL2L2,VEGFA,CCNE1,NRIP1,	8.83E-2
GO:0006457	protein folding	TTC1,DNAJC5,PPIL2,HSPA8,TCP1,HSP90AB1,PPIL1,	8.93E-2
GO:0022403	cell cycle phase	CCND1,BCL2,TARDBP,MPHOSPH9,PPP1CB,CHEK1,TBRG4,CDK4,SEPT2,CCNE1,CKAP5,	8.97E-2
GO:0045137	development of primary sexual characteristics	CCND1,BCL2,BCL2L2,VEGFA,CCNE1,NRIP1,	9.12E-2
GO:0032270	positive regulation of cellular protein metabolic process	CCND1,IFNG,BCL2,CDK4,PSMD7,NDFIP1,SMAD7,MAPK1,	9.19E-2

KEGG pathways and Gene Ontology terms enriched for the interacted genes of ncRNA from RAID and miRTarBase.

disease name	related genes	p-value