| Interacted genes from RAID,miRTarBase |
MMP7,SOX2,IRS1,IGFBP2,VEGFA,HOXA9,ADAM9,PITPNC1,TOM1,E2F1,RBMX,SPRED1,TWF1,PGR,VCAM1
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MMP7,SOX2,IRS1,IGFBP2,VEGFA,HOXA9,ADAM9,PITPNC1,TOM1,E2F1,RBMX,SPRED1,TWF1,PGR,VCAM1,CCNE2,CSGALNACT1,TEK,CRK,MERTK,PIK3R2,KRAS,SLC45A3,RGS3,DNMT1,PLK2,PTPN7,EGFL7,TWF2,CXCL12
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| KEGG pathways enriched for interacted genes |
| pathway name | pathway description | target genes enrich in pathway | p-value |
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hsa05211
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Renal cell carcinoma |
CRK,VEGFA,KRAS,PIK3R2, |
1.23E-2 |
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hsa05212
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Pancreatic cancer |
E2F1,VEGFA,KRAS,PIK3R2, |
1.33E-2 |
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hsa05220
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Chronic myeloid leukemia |
CRK,E2F1,KRAS,PIK3R2, |
1.50E-2 |
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hsa05215
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Prostate cancer |
CCNE2,E2F1,KRAS,PIK3R2, |
2.46E-2 |
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hsa05200
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Pathways in cancer |
CRK,CCNE2,E2F1,VEGFA,KRAS,PIK3R2, |
2.61E-2 |
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hsa04722
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Neurotrophin signaling pathway |
CRK,IRS1,KRAS,PIK3R2, |
6.28E-2 |
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hsa04960
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Aldosterone-regulated sodium reabsorption |
IRS1,KRAS,PIK3R2, |
7.08E-2 |
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hsa05219
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Bladder cancer |
E2F1,VEGFA,KRAS, |
7.42E-2 |
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hsa04910
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Insulin signaling pathway |
CRK,IRS1,KRAS,PIK3R2, |
7.95E-2 |
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hsa05223
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Non-small cell lung cancer |
E2F1,KRAS,PIK3R2, |
1.20E-1 |
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hsa05214
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Glioma |
E2F1,KRAS,PIK3R2, |
1.62E-1 |
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hsa04062
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Chemokine signaling pathway |
CRK,CXCL12,KRAS,PIK3R2, |
1.92E-1 |
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hsa05218
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Melanoma |
E2F1,KRAS,PIK3R2, |
2.03E-1 |
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hsa04370
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VEGF signaling pathway |
VEGFA,KRAS,PIK3R2, |
2.25E-1 |
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hsa05222
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Small cell lung cancer |
CCNE2,E2F1,PIK3R2, |
2.78E-1 |
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hsa04914
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Progesterone-mediated oocyte maturation |
PGR,KRAS,PIK3R2, |
2.90E-1 |
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hsa04012
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ErbB signaling pathway |
CRK,KRAS,PIK3R2, |
2.97E-1 |
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hsa04670
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Leukocyte transendothelial migration |
VCAM1,CXCL12,PIK3R2, |
5.18E-1 |
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hsa04360
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Axon guidance |
CXCL12,RGS3,KRAS, |
6.07E-1 |
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| Gene ontology terms enriched for interacted genes |
| GO terms | GO terms description | target genes enrich in GO term | p-value |
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GO:0030334
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regulation of cell migration |
EGFL7,CXCL12,VEGFA,TEK,IRS1,ADAM9, |
2.67E-5 |
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GO:0040012
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regulation of locomotion |
EGFL7,CXCL12,VEGFA,TEK,IRS1,ADAM9, |
4.92E-5 |
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GO:0051270
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regulation of cell motion |
EGFL7,CXCL12,VEGFA,TEK,IRS1,ADAM9, |
5.04E-5 |
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GO:0043549
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regulation of kinase activity |
CCNE2,RGS3,IRS1,KRAS,ADAM9,SPRED1, |
8.76E-4 |
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GO:0030335
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positive regulation of cell migration |
CXCL12,VEGFA,IRS1,ADAM9, |
8.88E-4 |
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GO:0051338
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regulation of transferase activity |
CCNE2,RGS3,IRS1,KRAS,ADAM9,SPRED1, |
1.05E-2 |
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GO:0042127
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regulation of cell proliferation |
SOX2,VCAM1,PGR,VEGFA,TEK,MMP7,IRS1,KRAS, |
1.10E-2 |
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GO:0040017
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positive regulation of locomotion |
CXCL12,VEGFA,IRS1,ADAM9, |
1.17E-2 |
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GO:0051272
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positive regulation of cell motion |
CXCL12,VEGFA,IRS1,ADAM9, |
1.17E-2 |
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GO:0042325
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regulation of phosphorylation |
CCNE2,RGS3,IRS1,KRAS,ADAM9,SPRED1, |
2.84E-2 |
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GO:0048732
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gland development |
SOX2,PGR,HOXA9,IRS1, |
2.93E-2 |
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GO:0051174
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regulation of phosphorus metabolic process |
CCNE2,RGS3,IRS1,KRAS,ADAM9,SPRED1, |
3.37E-2 |
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GO:0019220
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regulation of phosphate metabolic process |
CCNE2,RGS3,IRS1,KRAS,ADAM9,SPRED1, |
3.37E-2 |
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GO:0009967
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positive regulation of signal transduction |
SOX2,PLK2,VEGFA,IRS1,KRAS, |
3.42E-2 |
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GO:0010647
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positive regulation of cell communication |
SOX2,PLK2,VEGFA,IRS1,KRAS, |
5.04E-2 |
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GO:0045859
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regulation of protein kinase activity |
CCNE2,RGS3,KRAS,ADAM9,SPRED1, |
5.96E-2 |
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GO:0030879
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mammary gland development |
PGR,HOXA9,IRS1, |
7.99E-2 |
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KEGG pathways and Gene Ontology terms enriched for the interacted genes of ncRNA from RAID and miRTarBase.
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