ncRNADetailInformation

Detail Information
Functional analysis

miRNA name

pre-miRNA

family

pre-miRNA Sequence

mature-miRNA

mature sequence

pre-miRNA description

let-7e

MI0000066	MIPF0000002	CCCGGGCUGAGGUAGGAGGUUGUAUAGUUGAGGAGGACACCCAAGGAGAUCACUAUACGGCCUCCUAGCUUUCCCCAGG	MIMAT0000066 hsa-let-7e-5p	UGAGGUAGGAGGUUGUAUAGUU	The mature sequence shown here represents the most commonly cloned formfrom large-scale cloning studies .
MI0000066	MIPF0000002	CCCGGGCUGAGGUAGGAGGUUGUAUAGUUGAGGAGGACACCCAAGGAGAUCACUAUACGGCCUCCUAGCUUUCCCCAGG	MIMAT0004485 hsa-let-7e-3p	CUAUACGGCCUCCUAGCUUUCC	The mature sequence shown here represents the most commonly cloned formfrom large-scale cloning studies .
MI0000066	MIPF0000002	CCCGGGCUGAGGUAGGAGGUUGUAUAGUUGAGGAGGACACCCAAGGAGAUCACUAUACGGCCUCCUAGCUUUCCCCAGG	MIMAT0000066 hsa-let-7e-5p	UGAGGUAGGAGGUUGUAUAGUU	The mature sequence shown here represents the most commonly cloned formfrom large-scale cloning studies .
MI0000066	MIPF0000002	CCCGGGCUGAGGUAGGAGGUUGUAUAGUUGAGGAGGACACCCAAGGAGAUCACUAUACGGCCUCCUAGCUUUCCCCAGG	MIMAT0000066 hsa-let-7e-5p	UGAGGUAGGAGGUUGUAUAGUU	The mature sequence shown here represents the most commonly cloned formfrom large-scale cloning studies .
MI0000066	MIPF0000002	CCCGGGCUGAGGUAGGAGGUUGUAUAGUUGAGGAGGACACCCAAGGAGAUCACUAUACGGCCUCCUAGCUUUCCCCAGG	MIMAT0000066 hsa-let-7e-5p	UGAGGUAGGAGGUUGUAUAGUU	The mature sequence shown here represents the most commonly cloned formfrom large-scale cloning studies .

link to database

TargetScanS 6.2 | MicroCosm | microRNA.org | miRNAMap 2.0

Interacted genes from RAID,miRTarBase

FAM160B1,CREBBP,LSR,TUBA1B,PYCR1,ND3,MTCH2,C12orf49,SGSM3,PET112,STARD7,RCOR3,KATNB1,SEMA4B,HMGA2
more » FAM160B1,CREBBP,LSR,TUBA1B,PYCR1,ND3,MTCH2,C12orf49,SGSM3,PET112,STARD7,RCOR3,KATNB1,SEMA4B,HMGA2,PSD3,POLR3D,CCDC113,EIF4A1,IRS4,NCBP1,SPN,UROC1,RBM8A,ENSA,NCKIPSD,AEBP2,PRAMEF13,OR7D2,SUB1,IRGQ,MYCN,PIGS,APPL1,ZNF652,PAPD4,RPLP2,ANKRD40,PSMA6,MARCH5,PDP2,HIF1AN,CELF2,NRSN2,DAAM1,RPL10,CDC5L,ZNF256,CCDC97,WDR48,SLCO4A1,BRI3,HNRNPC,LRRC8A,PIGP,MACF1,SMAP2,C9orf86,PAX3,IVD,COX16,HIST2H2BF,JAZF1,CARM1,DTNB,SSB,PPP1R2,SCD,COL6A1,JMJD1C,SUGP2,KIAA0355,FDPS,CDKAL1,CTSA,TRPV1,ZNF805,C12orf62,SPTBN1,GNG5,GPM6B,UGGT1,COX1,STAT3,AMPD2,DCAF6,SCMH1,TERF1,PHF23,LMNA,FOXD4L6,SERBP1,COX3,PRRC2A,UHRF1BP1,MATR3,RUNX1T1,RPS27,ALG13,TTLL12,NUDT8,MTMR14,AGMAT,BTRC,COX10,ARHGAP19,PHKA1,CHD9,LHFPL2,SPATA13,UTP15,PGD,SPAG9,ARCN1,RSL1D1,POLD1,CTC1,YWHAQ,ND2,COPG,SETD1A,TNFAIP1,HIPK1,CENPP,ZNF284,SPCS3,CWC15,OTUB1,DZIP1,MKI67,NDST1,WDR4,VPS13D,EIF4EBP2,IGF2BP3,USE1,FAS,CABLES1,SUZ12,CHD7,DHX57,DCBLD2,PDCD11,C14orf43,OTUD5,PRPF8,CDCA3,PMPCA,WDFY3,PTK2,OCLN,PHF3,NF1,COPS8,CLTC,ATXN2L,PIGN,SLC12A4,GMPS,C15orf17,RBBP4,PPP2R1A,PSME4,RPN2,HNRNPUL1,SLC2A11,LMLN,EIF2C1,UBE2H,CCNG1,DIAPH1,RBM4,CLDN4,RNF26,GTF2I,RHBDD2,RNMT,ZNF673,PFAS,KIAA0100,MS4A10,CBX5,CYP2B6,C19orf48,EIF3J,NUDT15,DSP,PSMD2,RPL12,ATP6,GLUL,RBM14,SRSF2,ZNF451,RMND5A,VGLL4,DCAF8,MTFR1,RRAGC,SKA2,NUP155,CA5B,SALL1,EIF2C2,VARS,WDR67,SEC23IP,LUZP1,PA2G4,TRRAP,CNBP,SREBF1,ARID1A,SQLE,YWHAG,DGCR8,NCLN,NME4,NDUFA3,ZFP62,TIMP3,SVIL,NDUFS5,ND4,GPS1,ND1,TDRD7,BAZ1B,HLA-C,WNT1,BAHCC1,ZNF770,SCYL1,MYO9B,PPIG,CDH18,XIAP,PCBP2,SUPT4H1,CRK,HMGB1,MRPS2,EN2,ZNF167,VAMP2,TUBB4B,STAM,PES1,IRS2,SMC1A,CCDC106,NICN1,UBN2,RPA1,HS6ST2,UBAP2L,KATNAL1,NT5DC2,TNFRSF1A,NAA60,RPRD2,RACGAP1,IGF1R,TCF4,GTPBP8,SKIV2L,RPSA,NCKAP5L,RANBP2,UBE2V2,SPCS2,RAI2,BSDC1,TMEM107,YWHAE,ZFAND5,WBSCR16,BMP2K,MSMO1,QSOX1,ZFP3,SERF2,ND5,ZNF236,NOLC1,PPP1R10,SHANK1,RDX,PACS2,RPL27A,LRRC41,SLCO3A1,RAP1A,THADA,ARNT2,C11orf91,TIMM50,DYRK2,DHX15,COPS6,CCRN4L,MED13L,SLC38A2,GTF3C1,PLCXD1,USP37,MPL

KEGG pathways enriched for interacted genes

pathway name

pathway description

target genes enrich in pathway

p-value

hsa00190	Oxidative phosphorylation	COX10,ND4,ATP6,ND2,ND3,ND1,NDUFA3,COX1,ND5,NDUFS5,COX3,	1.85E-2
hsa05012	Parkinson's disease	ND4,ATP6,ND2,ND3,ND1,NDUFA3,COX1,ND5,NDUFS5,COX3,	6.18E-2
hsa03040	Spliceosome	RBM8A,CDC5L,DHX15,HNRNPC,NCBP1,PRPF8,CWC15,SRSF2,	1.87E-1
hsa04114	Oocyte meiosis	SMC1A,IGF1R,YWHAQ,PPP2R1A,BTRC,YWHAG,YWHAE,	3.11E-1
hsa03010	Ribosome	RPL12,RPLP2,RPL10,RPS27,RPSA,RPL27A,	3.93E-1

Gene ontology terms enriched for interacted genes

GO terms

GO terms description

target genes enrich in GO term

p-value

GO:0006396	RNA processing	SMC1A,CDC5L,EIF2C2,NOLC1,PES1,HNRNPUL1,PPIG,DHX15,PPP2R1A,CELF2,RRAGC,UTP15,RBM8A,RSL1D1,NCBP1,PCBP2,RNMT,PDCD11,PA2G4,PAPD4,HNRNPC,DGCR8,PRPF8,RBM4,SUGP2,WDR4,RBM14,CWC15,SSB,SRSF2,	5.37E-7
GO:0042773	ATP synthesis coupled electron transport	COX10,ND4,ATP6,ND2,ND3,ND1,NDUFA3,COX1,ND5,NDUFS5,COX3,	5.88E-7
GO:0042775	mitochondrial ATP synthesis coupled electron transport	COX10,ND4,ATP6,ND2,ND3,ND1,NDUFA3,COX1,ND5,NDUFS5,COX3,	5.88E-7
GO:0022904	respiratory electron transport chain	COX10,ND4,ATP6,ND2,ND3,ND1,NDUFA3,COX1,ND5,NDUFS5,COX3,	1.89E-6
GO:0045333	cellular respiration	COX10,ND4,ATP6,ND2,ND3,KIAA0100,ND1,NDUFA3,COX1,ND5,NDUFS5,COX3,	8.96E-6

GO:0015980	energy derivation by oxidation of organic compounds	COX10,PHKA1,ND5,NDUFS5,ATP6,ND4,ND2,KIAA0100,ND3,PPP1R2,ND1,NDUFA3,COX1,COX3,	1.05E-5
GO:0022900	electron transport chain	COX10,ND4,ATP6,ND2,ND3,ND1,NDUFA3,COX1,TXNRD1,ND5,NDUFS5,COX3,	3.72E-5
GO:0016071	mRNA metabolic process	SMC1A,RBM8A,CDC5L,EIF2C2,SERBP1,EIF2C1,NCBP1,PCBP2,RNMT,HNRNPUL1,PAPD4,DHX15,HNRNPC,PRPF8,RBM4,SUGP2,RBM14,CWC15,SSB,SRSF2,CELF2,	3.77E-5
GO:0006119	oxidative phosphorylation	COX10,ND4,ATP6,ND2,ND3,ND1,NDUFA3,COX1,ND5,NDUFS5,COX3,	6.37E-5
GO:0006120	mitochondrial electron transport, NADH to ubiquinone	ND4,ND2,ND3,ND1,NDUFA3,ND5,NDUFS5,	9.42E-5
GO:0006325	chromatin organization	SUZ12,TERF1,RBBP4,HMGB1,HMGA2,AEBP2,SUPT4H1,SETD1A,CHD9,CBX5,CARM1,HIST2H2BF,CREBBP,ARID1A,RBM4,BAZ1B,TRRAP,RBM14,JMJD1C,CHD7,	1.58E-4
GO:0008380	RNA splicing	SMC1A,RRAGC,RBM8A,CDC5L,NCBP1,PCBP2,HNRNPUL1,PPIG,DHX15,HNRNPC,PPP2R1A,PRPF8,RBM4,SUGP2,RBM14,CWC15,SRSF2,	1.84E-4
GO:0006397	mRNA processing	SMC1A,RBM8A,CDC5L,EIF2C2,NCBP1,PCBP2,RNMT,HNRNPUL1,PAPD4,DHX15,HNRNPC,PRPF8,RBM4,SUGP2,RBM14,CWC15,SRSF2,CELF2,	2.18E-4
GO:0016568	chromatin modification	SUZ12,TERF1,RBBP4,AEBP2,SETD1A,SUPT4H1,CHD9,CARM1,CREBBP,ARID1A,RBM4,BAZ1B,TRRAP,RBM14,JMJD1C,CHD7,	4.23E-4
GO:0051276	chromosome organization	SMC1A,SUZ12,TERF1,RBBP4,HMGB1,HMGA2,AEBP2,SUPT4H1,SETD1A,CHD9,CBX5,CARM1,HIST2H2BF,CREBBP,RPA1,ARID1A,RBM4,BAZ1B,TRRAP,RBM14,JMJD1C,CHD7,	4.56E-4
GO:0006091	generation of precursor metabolites and energy	COX10,PHKA1,RUNX1T1,TXNRD1,ND5,NDUFS5,ND4,ATP6,ND2,KIAA0100,ND3,PPP1R2,ND1,NDUFA3,COX1,COX3,	1.54E-2
GO:0006350	transcription	ZNF167,CDC5L,EIF2C2,STAT3,SUZ12,ZNF652,SUPT4H1,ZFP3,ZNF284,PHF3,CREBBP,SUB1,ZNF451,TCF4,RRAGC,PAX3,HIPK1,SALL1,RCOR3,RBBP4,EIF2C1,AEBP2,SETD1A,ARNT2,PA2G4,VGLL4,ZFP62,RBM4,TRRAP,RBM14,CNBP,ZNF256,RUNX1T1,ZNF236,POLR3D,HMGA2,JAZF1,ZNF805,HNRNPUL1,SCMH1,GTF3C1,PPP1R10,SCYL1,ARID1A,HIF1AN,JMJD1C,MED13L,C14orf43,CHD9,CARM1,CCRN4L,SREBF1,ZNF770,BAZ1B,GTF2I,CHD7,FOXD4L6,	1.89E-2
GO:0006412	translation	RPL12,RPLP2,RSL1D1,RPL10,EIF2C2,RPS27,VARS,MRPS2,RPL27A,PET112,IGF2BP3,EIF4A1,EIF3J,EIF4EBP2,RPSA,	2.57E-2
GO:0006123	mitochondrial electron transport, cytochrome c to oxygen	COX10,ATP6,COX1,COX3,	3.07E-2
GO:0055114	oxidation reduction	IVD,COX10,SQLE,QSOX1,ND5,TXNRD1,NDUFS5,ND4,ATP6,PYCR1,MSMO1,SCD,ND2,KIAA0100,ND3,ND1,NDUFA3,COX1,CYP2B6,JMJD1C,HIF1AN,COX3,PGD,	5.36E-2
GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	SMC1A,RBM8A,HNRNPC,NCBP1,PRPF8,PCBP2,HNRNPUL1,CWC15,SRSF2,	6.26E-2
GO:0000398	nuclear mRNA splicing, via spliceosome	SMC1A,RBM8A,HNRNPC,NCBP1,PRPF8,PCBP2,HNRNPUL1,CWC15,SRSF2,	6.26E-2
GO:0000375	RNA splicing, via transesterification reactions	SMC1A,RBM8A,HNRNPC,NCBP1,PRPF8,PCBP2,HNRNPUL1,CWC15,SRSF2,	6.26E-2
GO:0022402	cell cycle process	SMC1A,SGSM3,PSMD2,TERF1,POLD1,RACGAP1,BTRC,HMGA2,NOLC1,PES1,PA2G4,PSMA6,MACF1,SKA2,MKI67,CDCA3,RPA1,KATNB1,CCNG1,LMLN,	6.27E-2
GO:0007049	cell cycle	SMC1A,SGSM3,CDC5L,RACGAP1,APPL1,BTRC,HMGA2,PES1,NOLC1,SKA2,GPS1,CDCA3,RPA1,KATNB1,PSMD2,TERF1,POLD1,RBBP4,PA2G4,PSMA6,MACF1,CABLES1,MKI67,CCNG1,LMLN,	6.30E-2
GO:0006886	intracellular protein transport	YWHAQ,SPTBN1,STAM,ARCN1,SEC23IP,COPG,RANBP2,MACF1,CTSA,PPP1R10,CLTC,KATNB1,YWHAG,YWHAE,NCKIPSD,	7.52E-2
GO:0048285	organelle fission	COX10,SMC1A,SKA2,TERF1,CDCA3,KATNB1,HMGA2,CCNG1,LMLN,NOLC1,PES1,	8.25E-2
GO:0006414	translational elongation	RPL12,RPLP2,RPL10,RPS27,VARS,RPSA,RPL27A,	9.51E-2

KEGG pathways and Gene Ontology terms enriched for the interacted genes of ncRNA from RAID and miRTarBase.

disease name	related genes	p-value